All Relations between Ataxia and cerebellum

Publication Sentence Publish Date Extraction Date Species
Takehiro Takahashi, Milan Stoiljkovic, Eric Song, Xiao-Bing Gao, Yuki Yasumoto, Eriko Kudo, Fernando Carvalho, Yong Kong, Annsea Park, Marya Shanabrough, Klara Szigeti-Buck, Zhong-Wu Liu, Ashley Kristant, Yalan Zhang, Parker Sulkowski, Peter M Glazer, Leonard K Kaczmarek, Tamas L Horvath, Akiko Iwasak. LINE-1 activation in the cerebellum drives ataxia. Neuron. 2022-09-07. PMID:36070749. we demonstrated that l1 activation in the cerebellum led to purkinje cell dysfunctions and degeneration and was sufficient to cause ataxia. 2022-09-07 2023-08-14 mouse
Pallavi Asthana, Gajendra Kumar, Lukasz M Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K Wszolek, Chi Him Eddie M. Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression. NPJ Regenerative medicine. vol 7. issue 1. 2022-09-06. PMID:36064798. here, we demonstrated disrupted cerebellar circuitry and poor motor recovery in ataxia mice after pni. 2022-09-06 2023-08-14 mouse
Pallavi Asthana, Gajendra Kumar, Lukasz M Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K Wszolek, Chi Him Eddie M. Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression. NPJ Regenerative medicine. vol 7. issue 1. 2022-09-06. PMID:36064798. by restoring cerebellar circuitry through dcn stimulation, and reversal of neurotransmitter imbalance using baclofen, ataxia mice achieve full motor recovery after pni. 2022-09-06 2023-08-14 mouse
Albert Stezin, Pramod Kumar Pa. Treatable Ataxias: How to Find the Needle in the Haystack? Journal of movement disorders. 2022-09-06. PMID:36065614. treatable ataxias with immune-mediated etiologies include gluten ataxia, anti-glutamic acid decarboxylase antibody-associated ataxia, steroid-responsive encephalopathy associated with autoimmune thyroiditis, miller-fisher syndrome, multiple sclerosis, and paraneoplastic cerebellar degeneration. 2022-09-06 2023-08-14 Not clear
Albert Stezin, Pramod Kumar Pa. Treatable Ataxias: How to Find the Needle in the Haystack? Journal of movement disorders. 2022-09-06. PMID:36065614. infective and parainfectious causes of cerebellar ataxias include acute cerebellitis, postinfectious ataxia, whipple's disease, meningoencephalitis, and progressive multifocal leukoencephalopathy. 2022-09-06 2023-08-14 Not clear
Akira Takekoshi, Akio Kimura, Nobuaki Yoshikura, Isamu Yamakawa, Makoto Urushitani, Katsuya Nakamura, Kunihiro Yoshida, Takayoshi Shimohat. Clinical Features and Neuroimaging Findings of Neuropil Antibody-Positive Idiopathic Sporadic Ataxia of Unknown Etiology. Cerebellum (London, England). 2022-09-03. PMID:36057079. using tissue-based immunofluorescence assays (tbas), we examined antibodies against the cerebellum in serum samples from 67 patients who met the isa diagnostic criteria, including 30 patients with multiple system atrophy with predominant cerebellar features (msa-c) and 20 patients with hereditary ataxia (ha), and 18 healthy control subjects. 2022-09-03 2023-08-14 human
Gengyin Guo, Jianfeng Zhuang, Keke Zhang, Zhizhen Zhou, Yanjun Wang, Zhen Zhan. Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System in Children: Case Reports and Literature Review. Frontiers in surgery. vol 9. 2022-08-29. PMID:36034392. symptoms at presentation included increased intracranial pressure and cerebellar symptoms such as headache, altered gait, and ataxia. 2022-08-29 2023-08-14 Not clear
Yusra Mansour, Alyson Burchell, Randy Kulesz. Abnormal vestibular brainstem structure and function in an animal model of autism spectrum disorder. Brain research. 2022-08-19. PMID:35985362. we have recently shown that animals exposed to vpa in utero have fewer neurons in their auditory brainstem, reduced axonal projections to the auditory midbrain and thalamus, reduced expression of the calcium binding protein calbindin (cb) in the brainstem and cerebellum, smaller and occasionally ectopic cerebellar purkinje cells and ataxia on several motor tasks. 2022-08-19 2023-08-14 human
Kimberly Luttik, Leon Tejwani, Hyoungseok Ju, Terri Driessen, Cleo J L M Smeets, Chandrakanth Reddy Edamakanti, Aryaan Khan, Joy Yun, Puneet Opal, Janghoo Li. Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 34. 2022-08-15. PMID:35969780. spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including purkinje cells (pcs) in the cerebellum. 2022-08-15 2023-08-14 mouse
Jeremy D Schmahman. Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome-Implications and Future Directions. Cerebellum (London, England). 2022-08-10. PMID:35948744. it opened new avenues of investigation into higher order deficits that accompany the ataxias and other cerebellar diseases, as well as the contribution of cerebellar dysfunction to neuropsychiatric and neurocognitive disorders. 2022-08-10 2023-08-14 Not clear
Jeremy D Schmahman. Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome-Implications and Future Directions. Cerebellum (London, England). 2022-08-10. PMID:35948744. this new appreciation of the cerebellar incorporation into circuits that subserve cognition and emotion enables deeper understanding and improved care of our patients with cerebellar ataxias and novel cerebellar-based approaches to therapy in neuropsychiatry. 2022-08-10 2023-08-14 Not clear
Vincent Francis, Walaa Alshafie, Rahul Kumar, Martine Girard, Bernard Brais, Peter S McPherso. The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics. The Journal of biological chemistry. 2022-08-06. PMID:35933016. autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs) is a fatal brain disorder featuring cerebellar neurodegeneration leading to spasticity and ataxia. 2022-08-06 2023-08-14 Not clear
Ilaria Balbo, Francesca Montarolo, Federica Genovese, Filippo Tempia, Eriola Hoxh. Effects of the administration of Elovl5-dependent fatty acids on a spino-cerebellar ataxia 38 mouse model. Behavioral and brain functions : BBF. vol 18. issue 1. 2022-08-06. PMID:35933444. spinocerebellar ataxia 38 (sca38) is a rare autosomal neurological disorder characterized by ataxia and cerebellar atrophy. 2022-08-06 2023-08-14 mouse
Yui Tada, Kodai Kume, Soma Noguchi, Tomoko Sekiya, Kazuto Nishinaka, Hiroshi Ishiguchi, Jinsoo Koh, Seiji Emori, Yoshiaki Nakayama, Takashi Kurashige, Yuishin Izumi, Hidefumi Ito, Norio Sakai, Hideshi Kawakam. Comparison of two families with and without ataxia harboring novel variants in PRKCG. Journal of human genetics. 2022-06-27. PMID:35760954. patients in family 1 presented with only cerebellar atrophy without ataxia; however, patients in family 2 exhibited cerebellar ataxia, dystonia, and more severe cerebellar atrophy than those in family 1. 2022-06-27 2023-08-14 Not clear
Sze Yuen Lew, Michael Weng Lok Phang, Pit Shan Chong, Jaydeep Roy, Chi Him Poon, Wing Shan Yu, Lee Wei Lim, Kah Hui Won. Discovery of Therapeutics Targeting Oxidative Stress in Autosomal Recessive Cerebellar Ataxia: A Systematic Review. Pharmaceuticals (Basel, Switzerland). vol 15. issue 6. 2022-06-24. PMID:35745683. autosomal recessive cerebellar ataxias (arcas) are a heterogeneous group of rare neurodegenerative inherited disorders. 2022-06-24 2023-08-14 Not clear
Bettina L Serrallach, Gunes Orman, Eugen Boltshauser, Annette Hackenberg, Nilesh K Desai, Stephen F Kralik, Thierry A G M Huisma. Neuroimaging in cerebellar ataxia in childhood: A review. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2022-06-24. PMID:35749078. ataxia is one of the most common pediatric movement disorders and can be caused by a large number of congenital and acquired diseases affecting the cerebellum or the vestibular or sensory system. 2022-06-24 2023-08-14 Not clear
Hung-Chieh Chen, Li-Hua Lee, Jiing-Feng Lirng, Bing-Wen Soon. Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732792. we found that patients with msa-c tend to have a higher prevalence of pontine hcbs, worse scale for the assessment and rating of ataxia scores, lower cerebellar n-acetyl aspartate (naa)/creatinine (cr), and choline (cho)/cr, compared to patients with sca at corresponding disease stages. 2022-06-22 2023-08-14 Not clear
Arthur Cesário de Holanda, Eduardo Maranhão, Luísa Van Der Linden Ferreira Silva, Marcos Eugenio Ramalho Bezerra, Eduardo Sousa de Mel. Dengue fever presenting as acute cerebellar ataxia: Case report and literature review. Journal of neurovirology. 2022-06-09. PMID:35678983. among the seven other cases in which the relationship between dengue virus and ataxia was reported, only in one cerebellar presentation occurred as early. 2022-06-09 2023-08-14 Not clear
Allison Hilger, Caitlin Cloud, Taylor Fahe. Speech Impairment in Cerebellar Ataxia Affects Naturalness More Than Intelligibility. Cerebellum (London, England). 2022-06-07. PMID:35670895. the disruption of these cerebellar mechanisms has unique implications for how intelligibility and naturalness are affected in ataxia. 2022-06-07 2023-08-14 human
Kristin Mayoral-Palarz, Andreia Neves-Carvalho, Sara Duarte-Silva, Daniela Monteiro-Fernandes, Patrícia Maciel, Kamran Khodakha. Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3. Disease models & mechanisms. 2022-06-06. PMID:35660856. a feature of many cerebellar ataxias is aberrant cerebellar output that contributes to motor dysfunction. 2022-06-06 2023-08-14 mouse