| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Catelan, B Santini, F Sala, A Felett. Cerebellar mutism syndrome: the importance of preoperative language assessment. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2022-03-26. PMID:35338372. |
children undergoing surgical removal of tumors in the posterior cranial fossa can encounter a varied and complex constellation of neurological symptoms, called cerebellar mutism, defined as a disturbance in the planning and programming of motor language with preserved understanding, behavioral disorders such as inattention, visual-spatial disorganization, personality change, as well as ataxia and dysmetria. |
2022-03-26 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Kazuhiko Yamaguchi, Jerome Honnorat, Mario Mant. The Clinical Concept of LTDpathy: Is Dysregulated LTD Responsible for Prodromal Cerebellar Symptoms? Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326260. |
recent progress in ataxiology has identified dysregulation of pf-pc ltd in the pathophysiology of certain types of immune-mediated cerebellar ataxias (imcas). |
2022-03-25 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Kazuhiko Yamaguchi, Jerome Honnorat, Mario Mant. The Clinical Concept of LTDpathy: Is Dysregulated LTD Responsible for Prodromal Cerebellar Symptoms? Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326260. |
auto-antibodies towards voltage-gated ca channel (vgcc), metabotropic glutamate receptor type 1 (mglur1), and glutamate receptor delta (glur delta) induce dysfunction of pf-pc ltd, resulting in the development of cerebellar ataxias (cas). |
2022-03-25 |
2023-08-13 |
Not clear |
| Md Sorwer Alam Parvez, Gen Ohtsuk. Acute Cerebellar Inflammation and Related Ataxia: Mechanisms and Pathophysiology. Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326323. |
acute cerebellar inflammation and related ataxia: mechanisms and pathophysiology. |
2022-03-25 |
2023-08-13 |
Not clear |
| Marie Beaudin, Mario Manto, Jeremy D Schmahmann, Massimo Pandolfo, Nicolas Dupr. Recessive cerebellar and afferent ataxias - clinical challenges and future directions. Nature reviews. Neurology. 2022-03-25. PMID:35332317. |
recessive cerebellar and afferent ataxias - clinical challenges and future directions. |
2022-03-25 |
2023-08-13 |
Not clear |
| Marie Beaudin, Mario Manto, Jeremy D Schmahmann, Massimo Pandolfo, Nicolas Dupr. Recessive cerebellar and afferent ataxias - clinical challenges and future directions. Nature reviews. Neurology. 2022-03-25. PMID:35332317. |
cerebellar and afferent ataxias present with a characteristic gait disorder that reflects cerebellar motor dysfunction and sensory loss. |
2022-03-25 |
2023-08-13 |
Not clear |
| Dinkar Kulshreshtha, Jacky Ganguly, Mandar Jo. Expanding the Clinical Spectrum of RFC1 Gene Mutations. Journal of movement disorders. 2022-03-21. PMID:35306791. |
biallelic intronic repeat expansion in the replication factor complex unit 1 (rfc1) gene has recently been described as a cause of late onset ataxia with degeneration of the cerebellum, sensory pathways and the vestibular apparatus. |
2022-03-21 |
2023-08-13 |
Not clear |
| Deepa S Rajan, Sukhleen Kour, Tyler R Fortuna, Margot A Cousin, Sarah S Barnett, Zhiyv Niu, Dusica Babovic-Vuksanovic, Eric W Klee, Brian Kirmse, Micheil Innes, Siri Lynne Rydning, Kaja K Selmer, Magnus Dehli Vigeland, Anne Kjersti Erichsen, Andrea H Nemeth, Francisca Millan, Catherine DeVile, Katherine Fawcett, Adrien Legendre, David Sims, Ricardo Parolin Schnekenberg, Lydie Burglen, Sandra Mercier, Somayeh Bakhtiari, Encarnacion Martinez-Salas, Kristen Wigby, Jerica Lenberg, Jennifer R Friedman, Michael C Kruer, Udai Bhan Pande. Autosomal Recessive Cerebellar Atrophy and Spastic Ataxia in Patients With Pathogenic Biallelic Variants in Frontiers in cell and developmental biology. vol 10. 2022-03-17. PMID:35295849. |
autosomal recessive cerebellar atrophy and spastic ataxia in patients with pathogenic biallelic variants in the hereditary ataxias are a heterogenous group of disorders with an increasing number of causative genes being described. |
2022-03-17 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. |
2022-03-16 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
surprisingly, little is known about iron content in the cerebellar nuclei and its possible contribution to pathology in cerebellar ataxias, with the only exception of friedreich's ataxia. |
2022-03-16 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
seventy-nine patients with spinocerebellar ataxias of types 1, 2, 3 and 6; 15 patients with friedreich's ataxia; 18 patients with multiple system atrophy, cerebellar type and 111 healthy controls were also included. |
2022-03-16 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
the findings show that alterations in susceptibility revealed by quantitative susceptibility mapping are common in the dentate nuclei in different types of cerebellar ataxias. |
2022-03-16 |
2023-08-13 |
Not clear |
| Li Xu, Zichen Sun, Zhiyao Xing, Yutong Liu, Hongting Zhao, Zhongmin Tang, Yu Luo, Shuangying Hao, Kuanyu L. Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation. Journal of nanobiotechnology. vol 20. issue 1. 2022-03-10. PMID:35264205. |
abnormal iron metabolism, mitochondrial dysfunction and the derived oxidative damage are the main pathogeneses of friedrich's ataxia (frda), a single-gene inherited recessive neurodegenerative disease characterized by progressive cerebellar and sensory ataxia. |
2022-03-10 |
2023-08-13 |
mouse |
| Yu Jia, Mingyu Li, Dawei Li, Mengyao Zhang, Huifang Wang, Lidong Jiao, Zhaoyang Huang, Jing Ye, Aihua Liu, Yuping Wan. Immune-Mediated Cerebellar Ataxia Associated With Neuronal Surface Antibodies. Frontiers in immunology. vol 13. 2022-03-07. PMID:35250990. |
immune-mediated cerebellar ataxias (imcas) are common in paraneoplastic cerebellar degeneration (pcd) but rarely occur in patients with neuronal surface antibodies (nsabs). |
2022-03-07 |
2023-08-13 |
Not clear |
| Yu Jia, Mingyu Li, Dawei Li, Mengyao Zhang, Huifang Wang, Lidong Jiao, Zhaoyang Huang, Jing Ye, Aihua Liu, Yuping Wan. Immune-Mediated Cerebellar Ataxia Associated With Neuronal Surface Antibodies. Frontiers in immunology. vol 13. 2022-03-07. PMID:35250990. |
although cerebellar ataxias (cas) associated with anti-nmdar and anti-caspr2 have been reported in a few cases, they have never been studied systematically. |
2022-03-07 |
2023-08-13 |
Not clear |
| Hsin Fen Chien, Marise Bueno Zonta, Janini Chen, Giovana Diaferia, Celiana Figueiredo Viana, Hélio Afonso Ghizoni Teive, José Luiz Pedroso, Orlando Graziani Povoas Barsottin. Rehabilitation in patients with cerebellar ataxias. Arquivos de neuro-psiquiatria. 2022-03-03. PMID:35239817. |
rehabilitation in patients with cerebellar ataxias. |
2022-03-03 |
2023-08-13 |
Not clear |
| Hsin Fen Chien, Marise Bueno Zonta, Janini Chen, Giovana Diaferia, Celiana Figueiredo Viana, Hélio Afonso Ghizoni Teive, José Luiz Pedroso, Orlando Graziani Povoas Barsottin. Rehabilitation in patients with cerebellar ataxias. Arquivos de neuro-psiquiatria. 2022-03-03. PMID:35239817. |
cerebellar ataxias comprise a heterogeneous group of diseases characterized by motor and non-motor symptoms, which can be acquired, degenerative, or have a genetic cause, such as spinocerebellar ataxias (sca). |
2022-03-03 |
2023-08-13 |
Not clear |
| Hsin Fen Chien, Marise Bueno Zonta, Janini Chen, Giovana Diaferia, Celiana Figueiredo Viana, Hélio Afonso Ghizoni Teive, José Luiz Pedroso, Orlando Graziani Povoas Barsottin. Rehabilitation in patients with cerebellar ataxias. Arquivos de neuro-psiquiatria. 2022-03-03. PMID:35239817. |
usually, the genetic and neurodegenerative forms of cerebellar ataxias present a progressive and inevitable worsening of the clinical picture so that rehabilitation treatment is fundamental. |
2022-03-03 |
2023-08-13 |
Not clear |
| Xiang Chen, Tong Chen, Chen Dong, Huiyao Chen, Xinran Dong, Lin Yang, Liyuan Hu, Huijun Wang, Bingbing Wu, Ye Yao, Yu Xiong, Man Xiong, Yifeng Lin, Wenhao Zho. Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia and psychiatric behavior in mice. Journal of genetics and genomics = Yi chuan xue bao. 2022-03-01. PMID:35231638. |
deletion of chd8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia and psychiatric behavior in mice. |
2022-03-01 |
2023-08-13 |
mouse |
| H Brent Clar. The Neuropathology of Autoimmune Ataxias. Brain sciences. vol 12. issue 2. 2022-02-25. PMID:35204019. |
such factors as rapid rate of clinical progression, presence of known autoantibodies or the presence of a malignant neoplasm or other autoimmune disease processes need to be considered, particularly in cases where inflammatory changes are minimal or absent and the pathology is largely confined to the cerebellum and its connections, where the disease can mimic hereditary or other sporadic ataxias. |
2022-02-25 |
2023-08-13 |
Not clear |