| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mario Mascalchi, Alessandra Vell. Neuroimaging Applications in Chronic Ataxias. International review of neurobiology. vol 143. 2019-05-21. PMID:30473193. |
mri has a predominant diagnostic role in the single patient, based on the visual detection of three patterns of atrophy, namely, spinal atrophy, cortical cerebellar atrophy and olivopontocerebellar atrophy, which correlate with the aetiologies of inherited or sporadic ataxia. |
2019-05-21 |
2023-08-13 |
Not clear |
| Mario Mascalchi, Alessandra Vell. Neuroimaging Applications in Chronic Ataxias. International review of neurobiology. vol 143. 2019-05-21. PMID:30473193. |
in fact spinal atrophy is observed in friedreich ataxia, cortical cerebellar atrophy in ataxia telangectasia, gluten ataxia and sporadic adult onset ataxia and olivopontocerebellar atrophy in multiple system atrophy cerebellar type. |
2019-05-21 |
2023-08-13 |
Not clear |
| Mario Mascalchi, Alessandra Vell. Neuroimaging Applications in Chronic Ataxias. International review of neurobiology. vol 143. 2019-05-21. PMID:30473193. |
semiquantitative or quantitative mri, spect and pet data describing structural, microstructural and functional changes of the cerebellum, brainstem, and spinal cord have been widely applied to investigate physiopathological changes in patients with chronic ataxias. |
2019-05-21 |
2023-08-13 |
Not clear |
| Polina A Egorova, Alexandra V Gavrilova, Ilya B Bezprozvann. In Vivo Analysis of the Climbing Fiber-Purkinje Cell Circuit in SCA2-58Q Transgenic Mouse Model. Cerebellum (London, England). vol 17. issue 5. 2019-05-20. PMID:29876801. |
cerebellar purkinje cells (pcs) and cerebellar pathways are primarily affected in many autosomal dominant cerebellar ataxias. |
2019-05-20 |
2023-08-13 |
mouse |
| Ce Kang, Christina Liang, Kate E Ahmad, Yufan Gu, Sue-Faye Siow, James G Colebatch, Scott Whyte, Karl Ng, Philip D Cremer, Alastair J Corbett, Ryan L Davis, Tony Roscioli, Mark J Cowley, Jin-Sung Park, Carolyn M Sue, Kishore R Kuma. High Degree of Genetic Heterogeneity for Hereditary Cerebellar Ataxias in Australia. Cerebellum (London, England). vol 18. issue 1. 2019-05-20. PMID:30078120. |
high degree of genetic heterogeneity for hereditary cerebellar ataxias in australia. |
2019-05-20 |
2023-08-13 |
Not clear |
| Ce Kang, Christina Liang, Kate E Ahmad, Yufan Gu, Sue-Faye Siow, James G Colebatch, Scott Whyte, Karl Ng, Philip D Cremer, Alastair J Corbett, Ryan L Davis, Tony Roscioli, Mark J Cowley, Jin-Sung Park, Carolyn M Sue, Kishore R Kuma. High Degree of Genetic Heterogeneity for Hereditary Cerebellar Ataxias in Australia. Cerebellum (London, England). vol 18. issue 1. 2019-05-20. PMID:30078120. |
genetic testing strategies such as next-generation sequencing (ngs) panels and whole genome sequencing (wgs) can be applied to the hereditary cerebellar ataxias (hcas), but their exact role in the diagnostic pathway is unclear. |
2019-05-20 |
2023-08-13 |
Not clear |
| Elizabeth Berry-Kravis, Jamie Chin, Anne Hoffmann, Amy Winston, Robin Stoner, Lisa LaGorio, Katherine Friedmann, Mariana Hernandez, Daniel S Ory, Forbes D Porter, Joan A O'Keef. Long-Term Treatment of Niemann-Pick Type C1 Disease With Intrathecal 2-Hydroxypropyl-β-Cyclodextrin. Pediatric neurology. vol 80. 2019-05-10. PMID:29429782. |
intrathecal 2-hydoxypropyl-β-cyclodextrin has been found to mobilize cholesterol, extend life, reduce cerebellar pathology, and delay onset of ataxia in the mouse and cat models of niemann-pick disease, type c1, a clinically variable progressive and ultimately fatal neurodegenerative storage disorder characterized by endolysosomal accumulation of unesterified cholesterol. |
2019-05-10 |
2023-08-13 |
mouse |
| Kazunori Nanri, Nobuaki Yoshikura, Akio Kimura, Sayaka Nakayama, Takayuki Otomo, Takayoshi Shimohata, Hiroo Terashi, Tatsuya Sato, Junji Yamad. [Cerebellar Ataxia and Autoantibodies]. Brain and nerve = Shinkei kenkyu no shinpo. vol 70. issue 4. 2019-05-10. PMID:29632285. |
immune-mediated cerebellar ataxias include gluten ataxia, gad antibody-associated cerebellar ataxia, hashimoto's encephalopathy, and paraneoplastic cerebellar degeneration. |
2019-05-10 |
2023-08-13 |
Not clear |
| Andrea Cortese, Roberto Simone, Roisin Sullivan, Jana Vandrovcova, Huma Tariq, Wai Yan Yau, Jack Humphrey, Zane Jaunmuktane, Prasanth Sivakumar, James Polke, Muhammad Ilyas, Eloise Tribollet, Pedro J Tomaselli, Grazia Devigili, Ilaria Callegari, Maurizio Versino, Vincenzo Salpietro, Stephanie Efthymiou, Diego Kaski, Nick W Wood, Nadja S Andrade, Elena Buglo, Adriana Rebelo, Alexander M Rossor, Adolfo Bronstein, Pietro Fratta, Wilson J Marques, Stephan Züchner, Mary M Reilly, Henry Houlde. Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia. Nature genetics. vol 51. issue 4. 2019-04-19. PMID:30926972. |
late-onset ataxia is common, often idiopathic, and can result from cerebellar, proprioceptive, or vestibular impairment; when in combination, it is also termed cerebellar ataxia, neuropathy, vestibular areflexia syndrome (canvas). |
2019-04-19 |
2023-08-13 |
Not clear |
| Jose-Alberto Palma, Lucy Norcliffe-Kaufmann, Horacio Kaufman. Diagnosis of multiple system atrophy. Autonomic neuroscience : basic & clinical. vol 211. 2019-04-12. PMID:29111419. |
patients presenting with the cerebellar phenotype of msa can mimic other adult-onset ataxias due to alcohol, chemotherapeutic agents, lead, lithium, and toluene, or vitamin e deficiency, as well as paraneoplastic, autoimmune, or genetic ataxias. |
2019-04-12 |
2023-08-13 |
Not clear |
| Nutan Sharm. Neuropathology of Dystonia. Tremor and other hyperkinetic movements (New York, N.Y.). vol 9. 2019-04-12. PMID:30886764. |
neuropathologic research has been essential in understanding the etiology and disease progression of other movement disorders, including parkinson's disease and cerebellar ataxias. |
2019-04-12 |
2023-08-13 |
Not clear |
| Emanuele Barca, Valentina Emmanuele, Salvatore DiMauro, Antonio Toscano, Catarina M Quinzi. Anti-Oxidant Drugs: Novelties and Clinical Implications in Cerebellar Ataxias. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:29119930. |
anti-oxidant drugs: novelties and clinical implications in cerebellar ataxias. |
2019-04-10 |
2023-08-13 |
Not clear |
| Emanuele Barca, Valentina Emmanuele, Salvatore DiMauro, Antonio Toscano, Catarina M Quinzi. Anti-Oxidant Drugs: Novelties and Clinical Implications in Cerebellar Ataxias. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:29119930. |
hereditary cerebellar ataxias are a group of disorders characterized by heterogeneous clinical manifestations, progressive clinical course, and diverse genetic causes. |
2019-04-10 |
2023-08-13 |
Not clear |
| Roberta Ferrucci, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero, Alberto Prior. Noninvasive Cerebellar Stimulation as a Complement Tool to Pharmacotherapy. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:29141551. |
cerebellar ataxias represent a wide and heterogeneous group of diseases characterized by balance and coordination disturbance, dysarthria, dyssynergia and adyadococinesia, caused by a dysfunction in the cerebellum. |
2019-04-10 |
2023-08-13 |
Not clear |
| Roberta Ferrucci, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero, Alberto Prior. Noninvasive Cerebellar Stimulation as a Complement Tool to Pharmacotherapy. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:29141551. |
together with pharmacological studies, there has been growing interest in non-invasive cerebellar stimulation techniques to improve ataxia and limb coordination. |
2019-04-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Mario Manto, Christiane S Hamp. Immune-mediated Cerebellar Ataxias: Practical Guidelines and Therapeutic Challenges. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:30221603. |
immune-mediated cerebellar ataxias: practical guidelines and therapeutic challenges. |
2019-04-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Mario Manto, Christiane S Hamp. Immune-mediated Cerebellar Ataxias: Practical Guidelines and Therapeutic Challenges. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:30221603. |
immune-mediated cerebellar ataxias (imcas), a clinical entity reported for the first time in the 1980s, include gluten ataxia (ga), paraneoplastic cerebellar degenerations (pcds), antiglutamate decarboxylase 65 (gad) antibody-associated cerebellar ataxia, post-infectious cerebellitis, and opsoclonus myoclonus syndrome (oms). |
2019-04-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Mario Mant. The Era of Cerebellar Therapy. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:30582473. |
major advances in our understanding of the neurology/pathology, anatomy/physiology, and molecular biology of the cerebellum have opened a new door for cerebellar ataxias (cas). |
2019-04-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Mario Mant. The Era of Cerebellar Therapy. Current neuropharmacology. vol 17. issue 1. 2019-04-10. PMID:30582473. |
we discuss the hot topics in the therapeutic protocols available for cas, including aminopyridines, noninvasive cerebellar stimulation, anti-oxidant drugs and therapies for immune-mediated cerbellar ataxias (imcas), topics emphasized in this issue. |
2019-04-10 |
2023-08-13 |
Not clear |
| Juanette McKenzie, Curtis Oettel-Flaherty, Douglas Noel, Ruth H Walker, Andrew K Soberin. Pseudo-ataxia due to Osteoid Osteoma. Tremor and other hyperkinetic movements (New York, N.Y.). vol 9. 2019-04-03. PMID:30783555. |
ataxia is diagnosed by typical features on examination suggestive of a cerebellar etiology and can invoke extensive diagnostic testing. |
2019-04-03 |
2023-08-13 |
Not clear |