| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kimberley Stee, Mario Van Poucke, Mark Lowrie, Luc Van Ham, Luc Peelman, Natasha Olby, Sofie F M Bhatt. Phenotypic and genetic aspects of hereditary ataxia in dogs. Journal of veterinary internal medicine. 2023-06-21. PMID:37341581. |
hereditary ataxias are a large group of neurodegenerative diseases that have cerebellar or spinocerebellar dysfunction as core feature, occurring as an isolated sign or as part of a syndrome. |
2023-06-21 |
2023-08-14 |
Not clear |
| Kimberley Stee, Mario Van Poucke, Mark Lowrie, Luc Van Ham, Luc Peelman, Natasha Olby, Sofie F M Bhatt. Phenotypic and genetic aspects of hereditary ataxia in dogs. Journal of veterinary internal medicine. 2023-06-21. PMID:37341581. |
based on neuropathology, this group of diseases has so far been classified into cerebellar cortical degenerations, spinocerebellar degenerations, cerebellar ataxias without substantial neurodegeneration, canine multiple system degeneration, and episodic ataxia. |
2023-06-21 |
2023-08-14 |
Not clear |
| Kimberley Stee, Mario Van Poucke, Mark Lowrie, Luc Van Ham, Luc Peelman, Natasha Olby, Sofie F M Bhatt. Phenotypic and genetic aspects of hereditary ataxia in dogs. Journal of veterinary internal medicine. 2023-06-21. PMID:37341581. |
this review summarizes the current knowledge about hereditary ataxias in dogs, and proposes to add a "multifocal degenerations with predominant (spino)cerebellar component" category regrouping canine multiple system degeneration, new hereditary ataxia syndromes that do not fit in 1 of the previous categories, as well as specific neuroaxonal dystrophies and lysosomal storage diseases that cause major (spino)cerebellar dysfunction. |
2023-06-21 |
2023-08-14 |
Not clear |
| Gonzalo Olmedo-Saura, Jesús Pérez-Pérez, Tomás Xuclà-Ferrarons, Roger Collet, Ana Martínez-Viguera, Jaime Kulisevsk. Cerebellar Syndrome Induced by Hypomagnesemia: A Treatable Cause of Ataxia Not to be Missed. Report of Three Cases and a Review of the Literature. Movement disorders clinical practice. vol 10. issue 6. 2023-06-19. PMID:37332648. |
cerebellar syndrome induced by hypomagnesemia: a treatable cause of ataxia not to be missed. |
2023-06-19 |
2023-08-14 |
Not clear |
| Gilles Naeije, Antonin Rovai, Virginie Destrebecq, Nicolas Trotta, Xavier De Tièg. Anodal Cerebellar Transcranial Direct Current Stimulation Reduces Motor and Cognitive Symptoms in Friedreich's Ataxia: A Randomized, Sham-Controlled Trial. Movement disorders : official journal of the Movement Disorder Society. 2023-06-13. PMID:37310043. |
anodal cerebellar transcranial direct current stimulation reduces motor and cognitive symptoms in friedreich's ataxia: a randomized, sham-controlled trial. |
2023-06-13 |
2023-08-14 |
Not clear |
| Elizaveta A Olkhova, Laura A Smith, Carla Bradshaw, Gráinne S Gorman, Daniel Erskine, Yi Shiau N. Neurological Phenotypes in Mouse Models of Mitochondrial Disease and Relevance to Human Neuropathology. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298649. |
ataxia secondary to cerebellar impairment is one of the most prevalent neurological features of mouse models of mitochondrial dysfunction, consistent with the observation that progressive cerebellar ataxia is a common neurological manifestation in patients with mitochondrial disease. |
2023-06-11 |
2023-08-14 |
mouse |
| Hiroshi Mitom. [Immune-Mediated Cerebellar Ataxias]. Brain and nerve = Shinkei kenkyu no shinpo. vol 75. issue 6. 2023-06-08. PMID:37287357. |
[immune-mediated cerebellar ataxias]. |
2023-06-08 |
2023-08-14 |
Not clear |
| Hiroshi Mitom. [Immune-Mediated Cerebellar Ataxias]. Brain and nerve = Shinkei kenkyu no shinpo. vol 75. issue 6. 2023-06-08. PMID:37287357. |
autoimmune mechanisms affect the cerebellum leading to the development of cerebellar ataxias (cas), which are termed immune-mediated cerebellar ataxias (imcas). |
2023-06-08 |
2023-08-14 |
Not clear |
| Hiroshi Mitom. [Immune-Mediated Cerebellar Ataxias]. Brain and nerve = Shinkei kenkyu no shinpo. vol 75. issue 6. 2023-06-08. PMID:37287357. |
gluten ataxia (ga), post-infectious cerebellitis (pic), paraneoplastic cerebellar degeneration (pcd), opsoclonus myoclonus syndrome (oms), anti-glutamate decarboxylase 65 antibody-associated ca (anti-gad ataxia), and primary autoimmune cerebellar ataxia (paca). |
2023-06-08 |
2023-08-14 |
Not clear |
| Jessica Tiberi, Marco Segatto, Maria Teresa Fiorenza, Piergiorgio La Ros. Apparent Opportunities and Hidden Pitfalls: The Conflicting Results of Restoring NRF2-Regulated Redox Metabolism in Friedreich's Ataxia Pre-Clinical Models and Clinical Trials. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37238963. |
friedreich's ataxia (frda) is an autosomal, recessive, inherited neurodegenerative disease caused by the loss of activity of the mitochondrial protein frataxin (fxn), which primarily affects dorsal root ganglia, cerebellum, and spinal cord neurons. |
2023-05-27 |
2023-08-14 |
Not clear |
| Sourav Nanda, José Lapeña-Motilva, Amar Kumar Misra, Gautam Guha, Sinjan Ghosh, Akash Manna, Soumit Roy, Julián Benito-Leó. P300 Wave Alterations and Cognitive Impairment in Cerebellum Lesions. Cerebellum (London, England). 2023-05-26. PMID:37233909. |
the kolkata cognitive screening battery tasks and the frontal assessment battery (fab) were used to assess the cognitive status and the international cooperative ataxia rating scale (icars) for cerebellar signs. |
2023-05-26 |
2023-08-14 |
Not clear |
| Luke C Bartelt, Pawel M Switonski, Grażyna Adamek, Juliana Carvalho, Lisa A Duvick, Sabrina I Jarrah, Hayley S McLoughlin, Daniel R Scoles, Stefan M Pulst, Harry T Orr, Court Hull, Craig B Lowe, Albert R La Spad. Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214832. |
purkinje-enriched snrna-seq in sca7 cerebellum reveals zebrin identity loss as a central feature of polyglutamine ataxias. |
2023-05-23 |
2023-08-14 |
mouse |
| Alberto Benussi, Giorgi Batsikadze, Carina França, Rubens G Cury, Roderick P P W M Maa. The Therapeutic Potential of Non-Invasive and Invasive Cerebellar Stimulation Techniques in Hereditary Ataxias. Cells. vol 12. issue 8. 2023-05-16. PMID:37190102. |
the therapeutic potential of non-invasive and invasive cerebellar stimulation techniques in hereditary ataxias. |
2023-05-16 |
2023-08-14 |
Not clear |
| Alberto Benussi, Giorgi Batsikadze, Carina França, Rubens G Cury, Roderick P P W M Maa. The Therapeutic Potential of Non-Invasive and Invasive Cerebellar Stimulation Techniques in Hereditary Ataxias. Cells. vol 12. issue 8. 2023-05-16. PMID:37190102. |
the degenerative ataxias comprise a heterogeneous group of inherited and acquired disorders that are characterized by a progressive cerebellar syndrome, frequently in combination with one or more extracerebellar signs. |
2023-05-16 |
2023-08-14 |
Not clear |
| Alberto Benussi, Giorgi Batsikadze, Carina França, Rubens G Cury, Roderick P P W M Maa. The Therapeutic Potential of Non-Invasive and Invasive Cerebellar Stimulation Techniques in Hereditary Ataxias. Cells. vol 12. issue 8. 2023-05-16. PMID:37190102. |
in addition, a few smaller studies have explored deep brain stimulation (dbs) of the dentate nucleus as an invasive means to directly modulate cerebellar output, thereby aiming to alleviate ataxia severity. |
2023-05-16 |
2023-08-14 |
Not clear |
| Silvia Maria Marchese, Roberto Esposti, Veronica Farinelli, Claudia Ciaccio, Arianna De Laurentiis, Stefano D'Arrigo, Paolo Cavallar. Pediatric Slow-Progressive, but Not Non-Progressive Cerebellar Ataxia Delays Intra-Limb Anticipatory Postural Adjustments in the Upper Arm. Brain sciences. vol 13. issue 4. 2023-05-16. PMID:37190585. |
we recently investigated the role of the cerebellum during development, reporting that children with genetic slow-progressive ataxia (slowp) show worse postural control during quiet stance and gait initiation compared to healthy children (h). |
2023-05-16 |
2023-08-14 |
Not clear |
| Xia Liu, Wei Lin, Lin Zhang, Wan-Li Zhang, Xiao-Ping Cheng, Yan-Hua Lian, Meng-Cheng Li, Shi-Zhong Wang, Xin-Yuan Chen, Shi-Rui Ga. Effects of cerebellar transcranial alternating current stimulation in cerebellar ataxia: study protocol for a randomised controlled trial. Frontiers in neuroscience. vol 17. 2023-05-14. PMID:37179566. |
therefore, the aim of this study is to 1) examine whether cerebellar tacs improves ataxia severity and various non-motor symptoms in a homogeneous cohort of ca patients consisting of msa-c and sca3, 2) explore the time course of these effects, and 3) assess the safety and tolerance of cerebellar tacs in all participants. |
2023-05-14 |
2023-08-14 |
human |
| Marjolaine Tremblay, Bernard Brais, Véronique Asselin, Martin Buffet, André Girard, Denis Girard, Djamal Berbiche, Cynthia Gagno. The Development of a New Patient-Reported Outcome Measure in Recessive Ataxias: The Person-Reported Ataxia Impact Scale. Cerebellum (London, England). 2023-05-10. PMID:37165279. |
autosomal recessive cerebellar ataxias (arcas) are inherited neurological disorders that can affect both the central and peripheral nervous systems. |
2023-05-10 |
2023-08-14 |
Not clear |
| Athanasia Alexoudi, Eustathios Vlachakis, Spyros N Deftereos, Stefanos Korfias, Stylianos Gatzoni. Implantable Subcutaneous Peripheral Nerve Stimulation Improves Degenerative Ataxia. Cureus. vol 15. issue 4. 2023-05-04. PMID:37139025. |
degenerative cerebellar ataxias have no pharmacological or rehabilitation evidence-based treatment so far. |
2023-05-04 |
2023-08-14 |
Not clear |
| Shiqian Han, Qijun Wang, Yongfeng Song, Mao Pang, Chunguang Ren, Jing Wang, Dongwei Guan, Wei Xu, Fangyong Li, Fengchao Wang, Xinyuan Zhou, Carlos Fernández-Hernando, Huiwen Zhang, Dianqing Wu, Zhijia Y. Lithium ameliorates Niemann-Pick C1 disease phenotypes by impeding STING/SREBP2 activation. iScience. vol 26. issue 5. 2023-05-02. PMID:37128603. |
here, we show that lithium treatment improves ataxia and feeding phenotypes, attenuates cerebellar inflammation and degeneration, and extends survival in |
2023-05-02 |
2023-08-14 |
Not clear |