| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca A DeGiosio, Melanie J Grubisha, Matthew L MacDonald, Brandon C McKinney, Carlos J Camacho, Robert A Swee. More than a marker: potential pathogenic functions of MAP2. Frontiers in molecular neuroscience. vol 15. 2022-10-03. PMID:36187353. |
though pathology of tau has been well appreciated in the context of neurodegenerative disorders, the consequences of pathologically dysregulated map2 have been little explored, despite alterations in its immunoreactivity, expression, splicing and/or stability being observed in a variety of neurodegenerative and neuropsychiatric disorders including huntington's disease, prion disease, schizophrenia, autism, major depression and bipolar disorder. |
2022-10-03 |
2023-08-14 |
Not clear |
| Eric Shao, Che-Wei Chang, Zhiyong Li, Xinxing Yu, Kaitlyn Ho, Michelle Zhang, Xin Wang, Jeffrey Simms, Iris Lo, Jessica Speckart, Julia Holtzman, Gui-Qiu Yu, Erik D Roberson, Lennart Muck. TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model. Science translational medicine. vol 14. issue 642. 2022-04-27. PMID:35476595. |
tau ablation in excitatory neurons and postnatal tau knockdown reduce epilepsy, sudep, and autism behaviors in a dravet syndrome model. |
2022-04-27 |
2023-08-13 |
mouse |
| Andrea B Temkin, Renae Beaumont, Katarzyna Wkya, Jo R Hariton, Barabra L Flye, Elisabeth Sheridan, Amy Miranda, Jamie Vela, Elaina Zendegui, Jennifer Schild, Shannon Gasparro, Daphne Loubriel, Andreas Damiandies, Julia Weisman, Alexandra Silvestre, Mina Yadegar, Corinne Catarozoli, Shannon M Bennet. Secret Agent Society: A Randomized Controlled Trial of a Transdiagnostic Youth Social Skills Group Treatment. Research on child and adolescent psychopathology. 2022-04-20. PMID:35441908. |
this randomized control trial assessed whether the secret agent society (sas) group program was superior to treatment as usual (tau) in improving social-emotional functioning for children with attention deficit-hyperactivity disorder (adhd), autism spectrum disorder (asd), and/or anxiety. |
2022-04-20 |
2023-08-13 |
human |
| Fereshteh Mohammadzaheri, Lynn Kern Koegel, Zahra Soleymani, Reza Khosrowabadi, Enayatollah Bakhsh. Neural Correlates of Enhancing Question Asking and Initiations in Children with Autism Spectrum Disorders: A Randomized Clinical Trial. Social neuroscience. 2022-03-17. PMID:35296214. |
verbal children, diagnosed with autism, who lacked question asking in their communication were matched based on age and mean length utterance (mlu) and were randomly placed in either prt intervention or treatment as usual (tau) groups. |
2022-03-17 |
2023-08-13 |
Not clear |
| Lawrence Scahill, M Alice Shillingsburg, Opal Ousley, Moira L Pileggi, Rebecca L Kilbourne, Derianne Buckley, Scott E Gillespie, Courtney McCracke. A Randomized Trial of Direct Instruction Language for Learning in Children With Autism Spectrum Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 2022-01-30. PMID:35093490. |
to compare direct instruction language for learning (di) plus treatment as usual (tau) to tau alone in children with autism spectrum disorder and moderate language delay. |
2022-01-30 |
2023-08-13 |
Not clear |
| Magdalena Gąssowska-Dobrowolska, Agnieszka Kolasa-Wołosiuk, Magdalena Cieślik, Agnieszka Dominiak, Kristina Friedland, Agata Adamczy. Alterations in Tau Protein Level and Phosphorylation State in the Brain of the Autistic-Like Rats Induced by Prenatal Exposure to Valproic Acid. International journal of molecular sciences. vol 22. issue 6. 2021-04-30. PMID:33809910. |
since microtubules (mts) regulate dendritic spine morphology and play an important role in spine development and plasticity the aim of the present study was to investigate the alterations in the content of neuronal α/β-tubulin and tau protein level as well as phosphorylation state in the valproic acid (vpa)-induced rat model of autism. |
2021-04-30 |
2023-08-13 |
rat |
| Che-Wei Chang, Eric Shao, Lennart Muck. Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies. Science (New York, N.Y.). vol 371. issue 6532. 2021-03-09. PMID:33632820. |
several lines of evidence implicate the protein tau in the pathogenesis of multiple brain disorders, including alzheimer's disease, other neurodegenerative conditions, autism, and epilepsy. |
2021-03-09 |
2023-08-13 |
Not clear |
| Chao Tai, Che-Wei Chang, Gui-Qiu Yu, Isabel Lopez, Xinxing Yu, Xin Wang, Weikun Guo, Lennart Muck. Tau Reduction Prevents Key Features of Autism in Mouse Models. Neuron. vol 106. issue 3. 2020-08-24. PMID:32126198. |
our findings suggest an enabling role of tau in the pathogenesis of autism and identify tau reduction as a potential therapeutic strategy for some of the disorders that cause this condition. |
2020-08-24 |
2023-08-13 |
mouse |
| Chao Tai, Che-Wei Chang, Gui-Qiu Yu, Isabel Lopez, Xinxing Yu, Xin Wang, Weikun Guo, Lennart Muck. Tau Reduction Prevents Key Features of Autism in Mouse Models. Neuron. vol 106. issue 3. 2020-08-24. PMID:32126198. |
tau reduction prevents key features of autism in mouse models. |
2020-08-24 |
2023-08-13 |
mouse |
| Chao Tai, Che-Wei Chang, Gui-Qiu Yu, Isabel Lopez, Xinxing Yu, Xin Wang, Weikun Guo, Lennart Muck. Tau Reduction Prevents Key Features of Autism in Mouse Models. Neuron. vol 106. issue 3. 2020-08-24. PMID:32126198. |
here, we show that genetically reducing the protein tau prevents behavioral signs of autism in two mouse models simulating distinct causes of this condition. |
2020-08-24 |
2023-08-13 |
mouse |
| Meera E Modi, Mustafa Sahi. Tau: A Novel Entry Point for mTOR-Based Treatments in Autism Spectrum Disorder? Neuron. vol 106. issue 3. 2020-08-12. PMID:32380047. |
tau: a novel entry point for mtor-based treatments in autism spectrum disorder? |
2020-08-12 |
2023-08-13 |
Not clear |
| E A Duifhuis, J C den Boer, A Doornbos, J K Buitelaar, I J Oosterling, H Kli. The Effect of Pivotal Response Treatment in Children with Autism Spectrum Disorders: A Non-randomized Study with a Blinded Outcome Measure. Journal of autism and developmental disorders. vol 47. issue 2. 2017-09-15. PMID:27815645. |
children with autism spectrum disorder (asd), aged 3-8 years, received either prt (n = 11) or tau (n = 13). |
2017-09-15 |
2023-08-13 |
Not clear |
| E A Duifhuis, J C den Boer, A Doornbos, J K Buitelaar, I J Oosterling, H Kli. The Effect of Pivotal Response Treatment in Children with Autism Spectrum Disorders: A Non-randomized Study with a Blinded Outcome Measure. Journal of autism and developmental disorders. vol 47. issue 2. 2017-09-15. PMID:27815645. |
purpose of this quasi-experimental trial was to investigate the effect of pivotal response treatment (prt) versus treatment as usual (tau) on autism symptoms. |
2017-09-15 |
2023-08-13 |
Not clear |
| Roger Pamphlett, Stephen Kum Je. Locus ceruleus neurons in people with autism contain no histochemically-detectable mercury. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 29. issue 1. 2016-10-21. PMID:26613607. |
no increase in numbers of locus ceruleus neurons containing hyperphosphorylated tau was detected in people with autism. |
2016-10-21 |
2023-08-13 |
human |
| Roger Pamphlett, Stephen Kum Je. Locus ceruleus neurons in people with autism contain no histochemically-detectable mercury. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 29. issue 1. 2016-10-21. PMID:26613607. |
in addition, we sought evidence of damage to locus ceruleus neurons in autism by immunostaining for hyperphosphorylated tau. |
2016-10-21 |
2023-08-13 |
human |
| Muhammed Tayyib Kadak, Ihsan Cetin, Mahmut Cem Tarakçıoğlu, Ömer Faruk Özer, Selma Kaçar, Behzat Çime. Low Serum Level α-Synuclein and Tau Protein in Autism Spectrum Disorder Compared to Controls. Neuropediatrics. vol 46. issue 6. 2016-09-07. PMID:26479762. |
the aim of our study was to investigate serum α-syn and tau levels in autism. |
2016-09-07 |
2023-08-13 |
Not clear |
| Muhammed Tayyib Kadak, Ihsan Cetin, Mahmut Cem Tarakçıoğlu, Ömer Faruk Özer, Selma Kaçar, Behzat Çime. Low Serum Level α-Synuclein and Tau Protein in Autism Spectrum Disorder Compared to Controls. Neuropediatrics. vol 46. issue 6. 2016-09-07. PMID:26479762. |
our preliminary study suggests that low levels of serum α-syn and tau may be implicated in the relationship between synaptic activity and autism. |
2016-09-07 |
2023-08-13 |
Not clear |
| Muhammed Tayyib Kadak, Ihsan Cetin, Mahmut Cem Tarakçıoğlu, Ömer Faruk Özer, Selma Kaçar, Behzat Çime. Low Serum Level α-Synuclein and Tau Protein in Autism Spectrum Disorder Compared to Controls. Neuropediatrics. vol 46. issue 6. 2016-09-07. PMID:26479762. |
low serum level α-synuclein and tau protein in autism spectrum disorder compared to controls. |
2016-09-07 |
2023-08-13 |
Not clear |
| Muhammed Tayyib Kadak, Ihsan Cetin, Mahmut Cem Tarakçıoğlu, Ömer Faruk Özer, Selma Kaçar, Behzat Çime. Low Serum Level α-Synuclein and Tau Protein in Autism Spectrum Disorder Compared to Controls. Neuropediatrics. vol 46. issue 6. 2016-09-07. PMID:26479762. |
serum levels of α-syn and tau were measured, and autism spectrum disorder (asd) severity was assessed at admission using the childhood autism rating scale (cars) total score. |
2016-09-07 |
2023-08-13 |
Not clear |
| Magdalena Gąssowska, Irena Baranowska-Bosiacka, Joanna Moczydłowska, Maciej Tarnowski, Anna Pilutin, Izabela Gutowska, Lidia Strużyńska, Dariusz Chlubek, Agata Adamczy. Perinatal exposure to lead (Pb) promotes Tau phosphorylation in the rat brain in a GSK-3β and CDK5 dependent manner: Relevance to neurological disorders. Toxicology. vol 347-349. 2016-08-18. PMID:27012722. |
hyperphosphorylation of tau is involved in the pathomechanism of neurological disorders such as alzheimer's, parkinson's diseases as well as autism. |
2016-08-18 |
2023-08-13 |
rat |