All Relations between Autism Spectrum Disorder and hippocampus

Publication Sentence Publish Date Extraction Date Species
Peiyan Jiang, Lianyu Zhou, Linyang Zhao, Xinghang Fei, Zhifei Wang, Tianyao Liu, Yexi Tang, Dabing Li, Hong Gong, Yi Luo, Song Li, Hui Yang, Huiling Liao, Xiaotang Fa. Puerarin attenuates valproate-induced features of ASD in male mice via regulating Slc7a11-dependent ferroptosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-26. PMID:37491673. here, we found that the administration of puerarin from p12 to p15 ameliorated the autism-associated behaviors in the vpa-exposed male mouse model of autism by inhibiting ferroptosis in neural stem cells of the hippocampus. 2023-07-26 2023-08-14 mouse
Peiyan Jiang, Lianyu Zhou, Linyang Zhao, Xinghang Fei, Zhifei Wang, Tianyao Liu, Yexi Tang, Dabing Li, Hong Gong, Yi Luo, Song Li, Hui Yang, Huiling Liao, Xiaotang Fa. Puerarin attenuates valproate-induced features of ASD in male mice via regulating Slc7a11-dependent ferroptosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-26. PMID:37491673. we highlight the role of ferroptosis in the hippocampus neurogenesis and confirm that puerarin treatment inhibited iron overload, lipid peroxidation accumulation, and mitochondrial dysfunction, as well as enhanced the expression of ferroptosis inhibitory proteins, including nrf2, gpx4, slc7a11, and fth1 in the hippocampus of vpa mouse model of autism. 2023-07-26 2023-08-14 mouse
Peiyan Jiang, Lianyu Zhou, Linyang Zhao, Xinghang Fei, Zhifei Wang, Tianyao Liu, Yexi Tang, Dabing Li, Hong Gong, Yi Luo, Song Li, Hui Yang, Huiling Liao, Xiaotang Fa. Puerarin attenuates valproate-induced features of ASD in male mice via regulating Slc7a11-dependent ferroptosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-26. PMID:37491673. in conclusion, our study suggests that puerarin targets core symptoms and hippocampal neurogenesis reduction through ferroptosis inhibition, which might be a potential drug for autism intervention. 2023-07-26 2023-08-14 mouse
Qiao Mao, Shiren Huang, Xinqun Luo, Ping Liu, Xiaoping Wang, Kesheng Wang, Yong Zhang, Bin Chen, Xingguang Lu. Spatial Multiomics Analysis in Psychiatric Disorders. EC psychology and psychiatry. vol 12. issue 6. 2023-07-10. PMID:37424930. spatial proteogenomics has identified autism spectrum disorder (asd)-risk genes in specific cell types, while schizophrenia risk loci have been linked to transcriptional signatures in the human hippocampus. 2023-07-10 2023-08-14 mouse
Luisa Di Menna, Rosamaria Orlando, Giovanna D'Errico, Roxana Paula Ginerete, Agata Machaczka, Carmela M Bonaccorso, Andrea Arena, Michela Spatuzza, Roberta Celli, Marika Alborghetti, Eleonora Ciocca, Anna Rita Zuena, Maria Rosaria Scioli, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicoletti, Maria Vincenza Catani. Blunted type-5 metabotropic glutamate receptor-mediated polyphosphoinositide hydrolysis in two mouse models of monogenic autism. Neuropharmacology. 2023-07-01. PMID:37392820. the involvement of the mglu5 receptors in the pathophysiology of several forms of monogenic autism has been supported by numerous studies following the seminal observation that mglu5 receptor-dependent long-term depression was enhanced in the hippocampus of mice modeling the fragile-x syndrome (fxs). 2023-07-01 2023-08-14 mouse
Vardan Arutiunian, Elizaveta Davydova, Darya Pereverzeva, Alexander Sorokin, Svetlana Tyushkevich, Uliana Mamokhina, Kamilla Danilina, Olga Drago. Reduced grey matter volume of amygdala and hippocampus is associated with the severity of autistic symptoms and language abilities in school-aged children with Autism Spectrum Disorder: an exploratory study. Brain structure & function. 2023-06-11. PMID:37302090. reduced grey matter volume of amygdala and hippocampus is associated with the severity of autistic symptoms and language abilities in school-aged children with autism spectrum disorder: an exploratory study. 2023-06-11 2023-08-14 Not clear
Lene C Olsen, Meital Galler, Menno P Witter, Pål Saetrom, Kally C O'Reill. Transcriptional development of the hippocampus and the dorsal-intermediate-ventral axis in rats. Hippocampus. 2023-06-06. PMID:37280038. the dorsal-ventral axis of the hippocampus has behavioral, electrophysiological, anatomical, and transcriptional gradients and abnormal hippocampus development is associated with autism, schizophrenia, epilepsy, and mood disorders. 2023-06-06 2023-08-14 rat
Tatiana Ilchibaeva, Anton Tsybko, Marina Lipnitskaya, Dmitry Eremin, Kseniya Milutinovich, Vladimir Naumenko, Nina Popov. Brain-Derived Neurotrophic Factor (BDNF) in Mechanisms of Autistic-like Behavior in BTBR Mice: Crosstalk with the Dopaminergic Brain System. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37239153. for this reason, the aim of our study was to compare the effects of either the acute intracerebroventricular administration of a recombinant bdnf protein or hippocampal adeno-associated-virus-mediated bdnf overexpression on autistic-like behavior and expression of key da-related and bdnf-related genes in btbr mice (a widely recognized model of autism). 2023-05-27 2023-08-14 mouse
Hu Meng, Qiongwei Li, Jinxin Wang, Weihua Yue, Dai Zhang, Xiaoxuan Sun, Lifang Wang, Jun L. The expansion of newborn neurons in hippocampus improves social recognition deficit in a mouse model of autism. Frontiers in psychiatry. vol 14. 2023-05-23. PMID:37215664. the expansion of newborn neurons in hippocampus improves social recognition deficit in a mouse model of autism. 2023-05-23 2023-08-14 mouse
Sijie Chen, Longsheng Huang, Guihua Liu, Jie Kang, Qinfang Qian, Jingrong Wang, Rong Wang, Lizhen Zheng, Haijun Wang, Ping O. Acupuncture Ameliorated Behavioral Abnormalities in the Autism Rat Model via Pathways for Hippocampal Serotonin. Neuropsychiatric disease and treatment. vol 19. 2023-04-25. PMID:37096024. acupuncture ameliorated behavioral abnormalities in the autism rat model via pathways for hippocampal serotonin. 2023-04-25 2023-08-14 rat
Lanmin Guo, Zhi-Mei Jiang, Yu-Jun Zhan, Wei Pan, Qing-Wei Wu, Fan-Xu Song, Xue Zhou, Xin-Yu Zhou, Li-Jun Liu, Jing-Tao Wan. Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model. Journal of cellular physiology. 2023-03-24. PMID:36960573. neuro death through autophagy via the acetylation of foxo1 by sirt2 in the hippocampus of mice in a autism spectrum disorder mice model. 2023-03-24 2023-08-14 mouse
Sohir M Zohny, Mohamed Z Habib, Magda I Mohamad, Wael M Elayat, Reham M Elhossiny, Mohamed F Abd El-Salam, Ghada A M Hassan, Sawsan Aboul-Fotou. Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2023-03-15. PMID:36918475. memantine/aripiprazole combination alleviates cognitive dysfunction in valproic acid rat model of autism: hippocampal creb/bdnf signaling and glutamate homeostasis. 2023-03-15 2023-08-14 human
Masaaki Sato, Miki Kimura, Ai Ueda, Yuya Miyamot. [Imaging brain activity in virtual reality: abnormal hippocampal cognitive maps in autism model mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 158. issue 2. 2023-03-01. PMID:36858493. [imaging brain activity in virtual reality: abnormal hippocampal cognitive maps in autism model mice]. 2023-03-01 2023-08-14 mouse
Masaaki Sato, Miki Kimura, Ai Ueda, Yuya Miyamot. [Imaging brain activity in virtual reality: abnormal hippocampal cognitive maps in autism model mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 158. issue 2. 2023-03-01. PMID:36858493. in this review, we first overview the application of vr in rodent neuroscience, introduce our research on two-photon calcium imaging of the hippocampus of autism spectrum disorder (asd) model mice navigating a vr environment, and then discuss how hippocampal dysfunction can relate to asd phenotypes. 2023-03-01 2023-08-14 mouse
Annabella Pignataro, Paraskevi Krashia, Margherita De Introna, Annalisa Nobili, Annamaria Sabetta, Francesca Stabile, Livia La Barbera, Sebastian Luca D'Addario, Rossella Ventura, Francesco Cecconi, Marcello D'Amelio, Martine Ammassari-Teul. Chemogenetic rectification of the inhibitory tone onto hippocampal neurons reverts autistic-like traits and normalizes local expression of estrogen receptors in the Ambra1+/- mouse model of female autism. Translational psychiatry. vol 13. issue 1. 2023-02-22. PMID:36804922. chemogenetic rectification of the inhibitory tone onto hippocampal neurons reverts autistic-like traits and normalizes local expression of estrogen receptors in the ambra1+/- mouse model of female autism. 2023-02-22 2023-08-14 mouse
Li Zhang, Xiaowen Xu, Liya Ma, Xinxin Wang, Meifang Jin, Lili Li, Hong N. Zinc Water Prevents Autism-Like Behaviors in the BTBR Mice. Biological trace element research. 2023-01-05. PMID:36602746. zinc water reduces autism-like behavior in a partially inherited autism model mice-btbr-which may be associated with hippocampal neural precursor cell proliferation and reversed hyperexcitability. 2023-01-05 2023-08-14 mouse
Martina Sgritta, Beatrice Vignoli, Domenico Pimpinella, Marilena Griguoli, Spartaco Santi, Andrzej Bialowas, Grzegorz Wiera, Paola Zacchi, Francesca Malerba, Cristina Marchetti, Marco Canossa, Enrico Cherubin. Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations. iScience. vol 26. issue 1. 2022-12-30. PMID:36582822. impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal gabaergic-bdnf/trkb signaling alterations. 2022-12-30 2023-08-14 mouse
R Gioia, T Seri, T Diamanti, S Fimmanò, Marina Vitale, H Ahlenius, Z Kokaia, F Tirone, L Micheli, S Biagioni, G Lupo, A Rinaldi, A De Jaco, E Cacc. Adult hippocampal neurogenesis and social behavioural deficits in the R451C Neuroligin3 mouse model of autism are reverted by the antidepressant Fluoxetine. Journal of neurochemistry. 2022-12-30. PMID:36583243. adult hippocampal neurogenesis and social behavioural deficits in the r451c neuroligin3 mouse model of autism are reverted by the antidepressant fluoxetine. 2022-12-30 2023-08-14 mouse
Chuanqi Liu, Jiayin Liu, Hong Gong, Tianyao Liu, Xin Li, Xiaotang Fa. Implication of Hippocampal Neurogenesis in Autism Spectrum Disorder: Pathogenesis and Therapeutic Implications. Current neuropharmacology. 2022-12-22. PMID:36545727. implication of hippocampal neurogenesis in autism spectrum disorder: pathogenesis and therapeutic implications. 2022-12-22 2023-08-14 Not clear
Melissa J M Walsh, Edward Ofori, Broc A Pagni, Kewei Chen, Georgia Sullivan, B Blair Brade. Preliminary findings of accelerated visual memory decline and baseline brain correlates in middle-age and older adults with autism: The case for hippocampal free-water. Frontiers in aging neuroscience. vol 14. 2022-11-28. PMID:36437999. preliminary findings of accelerated visual memory decline and baseline brain correlates in middle-age and older adults with autism: the case for hippocampal free-water. 2022-11-28 2023-08-14 Not clear