All Relations between Autism Spectrum Disorder and hippocampus

Publication Sentence Publish Date Extraction Date Species
Júlio Santos-Terra, Iohanna Deckmann, Gustavo Brum Schwingel, André Vinicius Contri Paz, Clarissa S Gama, Victorio Bambini-Junior, Mellanie Fontes-Dutra, Carmem Gottfrie. Resveratrol prevents long-term structural hippocampal alterations and modulates interneuron organization in an animal model of ASD. Brain research. vol 1768. 2021-12-09. PMID:34331907. we aimed to evaluate histological parameters related to hippocampal morphology and to the distribution of parvalbumin- (pv), calbindin- (cb), and somatostatin-positive (som) interneurons sub-populations, in addition to evaluate the total/phosphorylation levels of pten, akt, gsk3β and total ck2 in the animal model of autism induced by vpa, as well as addressing the potential protective effect of rsv. 2021-12-09 2023-08-13 Not clear
Hiromu Okano, Kazumi Takashima, Yasunori Takahashi, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Mihoko Koyanagi, Robert R Maronpot, Toshinori Yoshida, Makoto Shibutan. Ameliorating effect of continuous alpha-glycosyl isoquercitrin treatment starting from late gestation in a rat autism model induced by postnatal injection of lipopolysaccharides. Chemico-biological interactions. 2021-12-05. PMID:34863679. the present study investigated the role of neuroinflammation and brain oxidative stress induced by neonatal treatment with lipopolysaccharides (lps) on the development of autism spectrum disorder (asd)-like behaviors and disruptive hippocampal neurogenesis in rats by exploring the chemopreventive effects of alpha-glycosyl isoquercitrin (agiq) as an antioxidant. 2021-12-05 2023-08-13 rat
Rosalia Paterno, Joseane Righes Marafiga, Harrison Ramsay, Tina Li, Kathryn A Salvati, Scott C Baraba. Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder. Cell reports. vol 37. issue 6. 2021-11-10. PMID:34758298. hippocampal gamma and sharp-wave ripple oscillations are altered in a cntnap2 mouse model of autism spectrum disorder. 2021-11-10 2023-08-13 mouse
S Durrleman, X Pennec, A Trouvé, J Braga, G Gerig, N Ayach. Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data. International journal of computer vision. vol 103. issue 1. 2021-10-21. PMID:23956495. in the context of neuroscience, we apply this method to analyze the differences in the growth of the hippocampus in children diagnosed with autism, developmental delays and in controls. 2021-10-21 2023-08-12 human
Sarah M Banker, Xiaosi Gu, Daniela Schiller, Jennifer H Foss-Fei. Hippocampal contributions to social and cognitive deficits in autism spectrum disorder. Trends in neurosciences. vol 44. issue 10. 2021-10-20. PMID:34521563. hippocampal contributions to social and cognitive deficits in autism spectrum disorder. 2021-10-20 2023-08-13 human
Isabel Barón-Mendoza, Emely Maqueda-Martínez, Mónica Martínez-Marcial, Marisol De la Fuente-Granada, Margarita Gómez-Chavarin, Aliesha González-Arena. Changes in the Number and Morphology of Dendritic Spines in the Hippocampus and Prefrontal Cortex of the C58/J Mouse Model of Autism. Frontiers in cellular neuroscience. vol 15. 2021-10-08. PMID:34616277. changes in the number and morphology of dendritic spines in the hippocampus and prefrontal cortex of the c58/j mouse model of autism. 2021-10-08 2023-08-13 mouse
Teruo Hashimoto, Susumu Yokota, Yutaka Matsuzaki, Ryuta Kawashim. Intrinsic hippocampal functional connectivity underlying rigid memory in children and adolescents with autism spectrum disorder: A case-control study. Autism : the international journal of research and practice. vol 25. issue 7. 2021-09-27. PMID:33779333. intrinsic hippocampal functional connectivity underlying rigid memory in children and adolescents with autism spectrum disorder: a case-control study. 2021-09-27 2023-08-13 Not clear
Katarina Ilic, Kristina Mlinac-Jerkovic, Goran Sedmak, Ivana Rosenzweig, Svjetlana Kalanj-Bogna. Neuroplastin in human cognition: review of literature and future perspectives. Translational psychiatry. vol 11. issue 1. 2021-08-02. PMID:34282131. here we summarize present knowledge about neuroplastin in human tissues and argue its genetic association with cortical thickness, intelligence, schizophrenia, and autism; specific immunolocalization depicting hippocampal trisynaptic pathway; potential role in tissue compensatory response in neurodegeneration; and high, almost housekeeping, level of spatio-temporal gene expression in the human brain. 2021-08-02 2023-08-13 mouse
Alessandra Bertoni, Fabienne Schaller, Roman Tyzio, Stephane Gaillard, Francesca Santini, Marion Xolin, Diabé Diabira, Radhika Vaidyanathan, Valery Matarazzo, Igor Medina, Elizabeth Hammock, Jinwei Zhang, Bice Chini, Jean-Luc Gaiarsa, Françoise Muscatell. Oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism. Molecular psychiatry. 2021-07-22. PMID:34290367. oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism. 2021-07-22 2023-08-13 mouse
Niels Haan, Laura J Westacott, Jenny Carter, Michael J Owen, William P Gray, Jeremy Hall, Lawrence S Wilkinso. Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34031371. haploinsufficiency of the schizophrenia and autism risk gene cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and arp2/3 mediated actin dependent mechanisms. 2021-07-14 2023-08-13 Not clear
Kimberly R Andrews, Brendan Epstein, Matthew S Leslie, Paul Fiedler, Phillip A Morin, A Rus Hoelze. Genomic signatures of divergent selection are associated with social behaviour for spinner dolphin ecotypes. Molecular ecology. vol 30. issue 9. 2021-06-21. PMID:33645853. gene ontology enrichment analyses indicated that outlier snps from both types of analyses were associated with multiple genes involved in social behaviour and hippocampus development, including 15 genes associated with the human social disorder autism. 2021-06-21 2023-08-13 human
Scheila Daiane Schmidt, Carolina Garrido Zinn, Jonny Anderson Kielbovicz Behling, Ana Flávia Furian, Cristiane Regina Guerino Furini, Jociane de Carvalho Myskiw, Ivan Izquierd. Inhibition of PACAP/PAC1/VPAC2 signaling impairs the consolidation of social recognition memory and nitric oxide prevents this deficit. Neurobiology of learning and memory. vol 180. 2021-06-18. PMID:33705861. evidence demonstrates that social deficits of psychiatric disorders such as autism and schizophrenia are caused by alterations in srm processing by the hippocampus and amygdala. 2021-06-18 2023-08-13 rat
Hyosun Choi, In Sik Kim, Ji Young Mu. Propionic acid induces dendritic spine loss by MAPK/ERK signaling and dysregulation of autophagic flux. Molecular brain. vol 13. issue 1. 2021-06-04. PMID:32487196. this study aimed to identify a link between ppa and autism phenotypes facilitated by signaling mechanisms in hippocampal neurons. 2021-06-04 2023-08-13 human
Chenxi Feng, Yajing Chen, Yuyang Zhang, Yinghui Yan, Mengjie Yang, Huan Gui, Mei Wan. PTEN Regulates Mitochondrial Biogenesis via the AKT/GSK-3β/PGC-1α Pathway in Autism. Neuroscience. vol 465. 2021-06-04. PMID:33895342. in the valproic acid (vpa) induced autism mouse model, the pten protein level was significantly decreased while pgc-1α and cox iv levels were increased in the hippocampus and cortex. 2021-06-04 2023-08-13 mouse
B Toczylowska, E Zieminska, P Senator, J W Lazarewic. Hippocampal Metabolite Profiles in Two Rat Models of Autism: NMR-Based Metabolomics Studies. Molecular neurobiology. vol 57. issue 7. 2021-05-19. PMID:32468248. hippocampal metabolite profiles in two rat models of autism: nmr-based metabolomics studies. 2021-05-19 2023-08-13 rat
Mingliang Bai, Dan Ye, Xudong Guo, Jiajie Xi, Nana Liu, Yukang Wu, Wenwen Jia, Guiying Wang, Wen Chen, Guoping Li, Zeyidan Jiapaer, Jiuhong Kan. Critical regulation of a NDIME/MEF2C axis in embryonic stem cell neural differentiation and autism. EMBO reports. vol 21. issue 11. 2021-04-27. PMID:33016573. moreover, the expression levels of both ndime and mef2c were strongly downregulated in the hippocampus of a mouse model of autism, and the adeno-associated virus (aav)-mediated expression of ndime in the hippocampus of these mice significantly increased mef2c expression and ameliorated autism-like behaviors. 2021-04-27 2023-08-13 mouse
Rose Richards, Ellen Greimel, Dorit Kliemann, Inga K Koerte, Gerd Schulte-Körne, Martin Reuter, Christian Wachinge. Increased hippocampal shape asymmetry and volumetric ventricular asymmetry in autism spectrum disorder. NeuroImage. Clinical. vol 26. 2021-03-26. PMID:32092683. increased hippocampal shape asymmetry and volumetric ventricular asymmetry in autism spectrum disorder. 2021-03-26 2023-08-13 Not clear
Vanessa P Reinhardt, Ana-Maria Iosif, Lauren Libero, Brianna Heath, Sally J Rogers, Emilio Ferrer, Christine Nordahl, Simona Ghetti, David Amaral, Marjorie Solomo. Understanding Hippocampal Development in Young Children With Autism Spectrum Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. vol 59. issue 9. 2021-03-18. PMID:31449875. understanding hippocampal development in young children with autism spectrum disorder. 2021-03-18 2023-08-13 human
Vanessa P Reinhardt, Ana-Maria Iosif, Lauren Libero, Brianna Heath, Sally J Rogers, Emilio Ferrer, Christine Nordahl, Simona Ghetti, David Amaral, Marjorie Solomo. Understanding Hippocampal Development in Young Children With Autism Spectrum Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. vol 59. issue 9. 2021-03-18. PMID:31449875. we examined growth trajectories of hippocampal volume (hv) in early childhood in a longitudinal cohort of male and female participants with autism spectrum disorder (asd) and typically developing (td) individuals, and investigated hv in those with large brains. 2021-03-18 2023-08-13 human
Hongyu Zhong, Rui Xiao, Ruotong Ruan, Hui Liu, Xin Li, Yun Cai, Jinghui Zhao, Xiaotang Fa. Neonatal curcumin treatment restores hippocampal neurogenesis and improves autism-related behaviors in a mouse model of autism. Psychopharmacology. vol 237. issue 12. 2021-02-16. PMID:32803366. neonatal curcumin treatment restores hippocampal neurogenesis and improves autism-related behaviors in a mouse model of autism. 2021-02-16 2023-08-13 mouse