| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Tomassoni-Ardori, Gianluca Fulgenzi, Jodi Becker, Colleen Barrick, Mary Ellen Palko, Skyler Kuhn, Vishal Koparde, Maggie Cam, Sudhirkumar Yanpallewar, Shalini Oberdoerffer, Lino Tessaroll. Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels. eLife. vol 8. 2020-01-31. PMID:31429825. |
we found that upregulation of rbfox1, an rna binding protein associated with intellectual disability, epilepsy and autism, increases selectively hippocampal trkb.t1 isoform expression. |
2020-01-31 |
2023-08-13 |
Not clear |
| Isabel Barón-Mendoza, Ireri Del Moral-Sánchez, Mónica Martínez-Marcial, Octavio García, Daniel Garzón-Cortés, Aliesha González-Arena. Dendritic complexity in prefrontal cortex and hippocampus of the autistic-like mice C58/J. Neuroscience letters. vol 703. 2019-10-29. PMID:30885632. |
autism spectrum disorder (asd) has been associated to atypical neuronal connectivity in the prefrontal cortex (pfc) and the hippocampus, in part, due to an alteration in neuroplasticity processes such as dendritic remodeling. |
2019-10-29 |
2023-08-13 |
mouse |
| Daoyin Dong, Horst Ronald Zielke, David Yeh, Peixin Yan. Cellular stress and apoptosis contribute to the pathogenesis of autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. vol 11. issue 7. 2019-10-02. PMID:29761862. |
this study compared the activation of er stress signals (protein kinase r-like endoplasmic reticulum kinase [perk], activating transcription factor 6 [atf6], inositol-requiring enzyme 1 alpha [ire1α]) in different brain regions (prefrontal cortex, hippocampus, cerebellum) in subjects with autism and in age-matched controls. |
2019-10-02 |
2023-08-13 |
human |
| David Abookasis, Danit Lerman, Hava Roth, Matanel Tfilin, Gadi Turgema. Optically derived metabolic and hemodynamic parameters predict hippocampal neurogenesis in the BTBR mouse model of autism. Journal of biophotonics. vol 11. issue 3. 2019-09-25. PMID:28800207. |
optically derived metabolic and hemodynamic parameters predict hippocampal neurogenesis in the btbr mouse model of autism. |
2019-09-25 |
2023-08-13 |
mouse |
| Xiaokuang Ma, Ke Chen, Zhongming Lu, Mariel Piechowicz, Qiang Liu, Jie Wu, Shenfeng Qi. Disruption of MET Receptor Tyrosine Kinase, an Autism Risk Factor, Impairs Developmental Synaptic Plasticity in the Hippocampus. Developmental neurobiology. vol 79. issue 1. 2019-07-30. PMID:30304576. |
disruption of met receptor tyrosine kinase, an autism risk factor, impairs developmental synaptic plasticity in the hippocampus. |
2019-07-30 |
2023-08-13 |
mouse |
| Yousuke Watanabe, Kota Nakajima, Yuko Ito, Yumi Akahori, Fumiyo Saito, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Twenty-eight-day repeated oral doses of sodium valproic acid increases neural stem cells and suppresses differentiation of granule cell lineages in adult hippocampal neurogenesis of postpubertal rats. Toxicology letters. vol 312. 2019-07-01. PMID:31085223. |
developmental exposure to valproic acid (vpa), a model compound for experimental autism, has shown to primarily target gabaergic interneuron subpopulations in hippocampal neurogenesis of rat offspring. |
2019-07-01 |
2023-08-13 |
rat |
| Yu-Ting Lin, Kuei-Sen Hs. Oxytocin receptor signaling in the hippocampus: Role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social memory. Progress in neurobiology. vol 171. 2019-04-12. PMID:30359747. |
a full understanding of the functional role of hippocampal oxtr signaling may lead to targeted new therapies for social cognition deficits, often observed in patients with autism and other neuropsychiatric disorders. |
2019-04-12 |
2023-08-13 |
Not clear |
| Kwan Young Lee, Kathryn A Jewett, Hee Jung Chung, Nien-Pei Tsa. Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2. Human molecular genetics. vol 27. issue 16. 2019-03-08. PMID:29771335. |
here, we showed that the homeostatic synaptic downscaling is absent in the hippocampal neurons of fmr1 ko mice, the mouse model of the most common inherited autism, fragile x syndrome (fxs). |
2019-03-08 |
2023-08-13 |
mouse |
| Kaori Yagishita, Ritsuko Suzuki, Shota Mizuno, Ritsuko Katoh-Semba, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuichi, Yo Shinod. CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus. Neuroscience letters. vol 661. 2018-07-26. PMID:28963059. |
hippocampal adult neurogenesis is observed in the subgranular zone of the dentate gyrus (dg), and is associated with hippocampal memory formation and several psychiatric disorders including autism spectrum disorder (asd). |
2018-07-26 |
2023-08-13 |
mouse |
| Ahmad Chaddad, Christian Desrosiers, Lama Hassan, Camel Tanougas. Hippocampus and amygdala radiomic biomarkers for the study of autism spectrum disorder. BMC neuroscience. vol 18. issue 1. 2018-07-24. PMID:28821235. |
hippocampus and amygdala radiomic biomarkers for the study of autism spectrum disorder. |
2018-07-24 |
2023-08-13 |
human |
| Giada Cellot, Laura Maggi, Maria Amalia Di Castro, Myriam Catalano, Rosanna Migliore, Michele Migliore, Maria Luisa Scattoni, Gemma Calamandrei, Enrico Cherubin. Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice. Scientific reports. vol 6. 2018-07-03. PMID:27526668. |
here, we show that, immediately after birth, in the ca3 hippocampal region of the btbr t+tf/j mouse, an animal model of idiopathic autism, gdps are severely impaired. |
2018-07-03 |
2023-08-13 |
mouse |
| Jameson Patak, Jonathan L Hess, Yanli Zhang-James, Stephen J Glatt, Stephen V Faraon. SLC9A9 Co-expression modules in autism-associated brain regions. Autism research : official journal of the International Society for Autism Research. vol 10. issue 3. 2018-04-23. PMID:27439572. |
we found a disproportionately high autism risk signal among genes constituting the prenatal hippocampal module. |
2018-04-23 |
2023-08-13 |
Not clear |
| Thomas C Jaramillo, Haley E Speed, Zhong Xuan, Jeremy M Reimers, Christine Ochoa Escamilla, Travis P Weaver, Shunan Liu, Irina Filonova, Craig M Powel. Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function. Autism research : official journal of the International Society for Autism Research. vol 10. issue 1. 2018-04-04. PMID:27492494. |
novel shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function. |
2018-04-04 |
2023-08-13 |
mouse |
| Rose A Cooper, Franziska R Richter, Paul M Bays, Kate C Plaisted-Grant, Simon Baron-Cohen, Jon S Simon. Reduced Hippocampal Functional Connectivity During Episodic Memory Retrieval in Autism. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 2. 2018-02-26. PMID:28057726. |
reduced hippocampal functional connectivity during episodic memory retrieval in autism. |
2018-02-26 |
2023-08-13 |
human |
| Melanie Ring, Claire L T Derwent, Sebastian B Gaigg, Dermot M Bowle. Structural learning difficulties implicate altered hippocampal functioning in adults with autism spectrum disorder. Journal of abnormal psychology. vol 126. issue 6. 2018-02-12. PMID:28557507. |
structural learning difficulties implicate altered hippocampal functioning in adults with autism spectrum disorder. |
2018-02-12 |
2023-08-13 |
human |
| A Özge Sungur, Magdalena C E Jochner, Hani Harb, Ayşe Kılıç, Holger Garn, Rainer K W Schwarting, Markus Wöh. Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder. Hippocampus. vol 27. issue 8. 2018-02-02. PMID:28500650. |
aberrant cognitive phenotypes and altered hippocampal bdnf expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein shank1: implications for autism spectrum disorder. |
2018-02-02 |
2023-08-13 |
mouse |
| Ning Cheng, Fawaz Alshammari, Elizabeth Hughes, Maryam Khanbabaei, Jong M Rh. Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism. PloS one. vol 12. issue 6. 2017-09-25. PMID:28609458. |
alterations in network connectivity and memory function are frequently observed in autism patients, often involving the hippocampus. |
2017-09-25 |
2023-08-13 |
mouse |
| Francisco Peralta, Constanza Fuentealba, Jenny Fiedler, Esteban Aliag. Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor 1A-immunoreactivity in the hippocampus of juvenile rats. Molecular medicine reports. vol 14. issue 3. 2017-04-06. PMID:27430241. |
these results suggested an over‑functioning of mglur1a signaling in the hippocampus, induced in the valproate model of autism, which may serve a role in cognitive and behavioral signs of asd. |
2017-04-06 |
2023-08-13 |
rat |
| Jinlong Zhou, Xiaozheng Zhang, Junrong Ren, Ping Wang, Junfeng Zhang, Zhaoming Wei, Yingfang Tia. Validation of reference genes for quantitative real-time PCR in valproic acid rat models of autism. Molecular biology reports. vol 43. issue 8. 2017-02-14. PMID:27287459. |
the aim of the current study is to validate suitable reference genes for quantitative real-time pcr (qpcr) quantification in prefrontal cortex and hippocampus of vpa rat models of autism. |
2017-02-14 |
2023-08-13 |
rat |
| Jingquan Gao, Xuelai Wang, Hongli Sun, Yonggang Cao, Shuang Liang, Han Wang, Yanming Wang, Feng Yang, Fengyu Zhang, Lijie W. Neuroprotective effects of docosahexaenoic acid on hippocampal cell death and learning and memory impairments in a valproic acid-induced rat autism model. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 49. 2016-12-13. PMID:26639559. |
neuroprotective effects of docosahexaenoic acid on hippocampal cell death and learning and memory impairments in a valproic acid-induced rat autism model. |
2016-12-13 |
2023-08-13 |
rat |