| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adi Aran, Moria Harel, Hanoch Cassuto, Lola Polyansky, Aviad Schnapp, Nadia Wattad, Dorit Shmueli, Daphna Golan, F Xavier Castellano. Cannabinoid treatment for autism: a proof-of-concept randomized trial. Molecular autism. vol 12. issue 1. 2021-09-24. PMID:33536055. |
cannabinoid treatment for autism: a proof-of-concept randomized trial. |
2021-09-24 |
2023-08-13 |
human |
| Adi Aran, Moria Harel, Hanoch Cassuto, Lola Polyansky, Aviad Schnapp, Nadia Wattad, Dorit Shmueli, Daphna Golan, F Xavier Castellano. Cannabinoid treatment for autism: a proof-of-concept randomized trial. Molecular autism. vol 12. issue 1. 2021-09-24. PMID:33536055. |
endocannabinoid dysfunction in animal models of autism spectrum disorder (asd) and accumulating, albeit anecdotal, evidence for efficacy in humans motivated this placebo-controlled double-blind comparison of two oral cannabinoid solutions in 150 participants (age 5-21 years) with asd. |
2021-09-24 |
2023-08-13 |
human |
| William Fyke, Juan Marcos Alarcon, Milen Velinov, Kathryn K Chadma. Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-α, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice. Autism research : official journal of the International Society for Autism Research. vol 14. issue 7. 2021-08-12. PMID:33886158. |
accumulating evidence links dysfunction in the endocannabinoid system (ecs) with the pathology of neurodevelopmental disorders, particularly autism spectrum disorder (asd). |
2021-08-12 |
2023-08-13 |
mouse |
| William Fyke, Juan Marcos Alarcon, Milen Velinov, Kathryn K Chadma. Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-α, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice. Autism research : official journal of the International Society for Autism Research. vol 14. issue 7. 2021-08-12. PMID:33886158. |
in this study, pharmacological inhibition of the primary endocannabinoid producing enzyme, dgl-α, induced a constellation of deficits in behavioral domains associated with autism. |
2021-08-12 |
2023-08-13 |
mouse |
| Aoife M Thornton, Rachel M Humphrey, Daniel M Kerr, David P Finn, Michelle Roch. Increasing Endocannabinoid Tone Alters Anxiety-Like and Stress Coping Behaviour in Female Rats Prenatally Exposed to Valproic Acid. Molecules (Basel, Switzerland). vol 26. issue 12. 2021-07-13. PMID:34207178. |
the aim of the present study was to use the valproic acid (vpa) model of autism to compare the behavioural responses of male and female rats and examine the effects of increasing endocannabinoid tone on the behavioural responses of vpa-exposed female rats. |
2021-07-13 |
2023-08-13 |
rat |
| Aoife M Thornton, Rachel M Humphrey, Daniel M Kerr, David P Finn, Michelle Roch. Increasing Endocannabinoid Tone Alters Anxiety-Like and Stress Coping Behaviour in Female Rats Prenatally Exposed to Valproic Acid. Molecules (Basel, Switzerland). vol 26. issue 12. 2021-07-13. PMID:34207178. |
thus, considerations should be paid to the possible sex-specific effects of cannabinoids for the treatment of symptoms associated with autism. |
2021-07-13 |
2023-08-13 |
rat |
| Emilia Carbone, Antonia Manduca, Claudia Cacchione, Stefano Vicari, Viviana Trezz. Healing autism spectrum disorder with cannabinoids: a neuroinflammatory story. Neuroscience and biobehavioral reviews. vol 121. 2021-06-21. PMID:33358985. |
healing autism spectrum disorder with cannabinoids: a neuroinflammatory story. |
2021-06-21 |
2023-08-13 |
Not clear |
| Estácio Amaro da Silva, Wandersonia Moreira Brito Medeiros, Nelson Torro, João Marçal Medeiros de Sousa, Igor Bronzeado Cahino Moura de Almeida, Filipe Barbosa da Costa, Katiúscia Moreira Pontes, Eliane Lima Guerra Nunes, Marine Diniz da Rosa, Katy Lísias Gondim Dias de Albuquerqu. Cannabis and cannabinoid use in autism spectrum disorder: a systematic review. Trends in psychiatry and psychotherapy. 2021-05-27. PMID:34043900. |
cannabis and cannabinoid use in autism spectrum disorder: a systematic review. |
2021-05-27 |
2023-08-13 |
Not clear |
| Juliana Andrea Ponton, Kim Smyth, Elias Soumbasis, Sergio Andres Llanos, Mark Lewis, Wilhelm August Meerholz, Robert Lawrence Tangua. A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report. Journal of medical case reports. vol 14. issue 1. 2021-05-14. PMID:32958062. |
a pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report. |
2021-05-14 |
2023-08-13 |
Not clear |
| Stephen Schultz, Georgianna G Gould, Nicola Antonucci, Anna Lisa Brigida, Dario Siniscalc. Endocannabinoid System Dysregulation from Acetaminophen Use May Lead to Autism Spectrum Disorder: Could Cannabinoid Treatment Be Efficacious? Molecules (Basel, Switzerland). vol 26. issue 7. 2021-05-12. PMID:33805951. |
endocannabinoid system dysregulation from acetaminophen use may lead to autism spectrum disorder: could cannabinoid treatment be efficacious? |
2021-05-12 |
2023-08-13 |
human |
| Tangfeng Su, Lei Pe. Acupuncture and oxytocinergic system: The promising treatment for autism. Translational neuroscience. vol 12. issue 1. 2021-02-27. PMID:33633868. |
recently, the endocannabinoid system has emerged as a promising target for the treatment of autism. |
2021-02-27 |
2023-08-13 |
mouse |
| Jon DelaCuesta-Barrutia, Olga Peñagarikano, Amaia M Erdozai. G Protein-Coupled Receptor Heteromers as Putative Pharmacotherapeutic Targets in Autism. Frontiers in cellular neuroscience. vol 14. 2020-11-17. PMID:33192330. |
among these, the dopaminergic, oxytocinergic, serotonergic, and cannabinoid systems have also been implicated in autism and thus represent putative therapeutic targets. |
2020-11-17 |
2023-08-13 |
Not clear |
| Daniel John Araujo, Karensa Tjoa, Kaoru Saij. The Endocannabinoid System as a Window Into Microglial Biology and Its Relationship to Autism. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31619967. |
the endocannabinoid system as a window into microglial biology and its relationship to autism. |
2020-09-30 |
2023-08-13 |
Not clear |
| D S Karhson, A Y Hardan, K J Parke. Endocannabinoid signaling in social functioning: an RDoC perspective. Translational psychiatry. vol 6. issue 9. 2019-11-20. PMID:27676446. |
the empirical evidence reviewed strongly supports the role for dysregulated cannabinoid signaling in the pathophysiology of social functioning deficits observed in brain disorders, such as autism spectrum disorder, schizophrenia, major depressive disorder, posttraumatic stress disorder and bipolar disorder. |
2019-11-20 |
2023-08-13 |
Not clear |
| Brian C Shonesy, Walker P Parrish, Hala K Haddad, Jason R Stephenson, Rita Báldi, Rebecca J Bluett, Christian R Marks, Samuel W Centanni, Oakleigh M Folkes, Keeley Spiess, Shana M Augustin, Ken Mackie, David M Lovinger, Danny G Winder, Sachin Patel, Roger J Colbra. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biological psychiatry. vol 84. issue 4. 2019-10-04. PMID:29458998. |
endocannabinoid signaling plays an important role in regulating synaptic transmission in the striatum, a brain region implicated as a central node of dysfunction in autism spectrum disorder. |
2019-10-04 |
2023-08-13 |
mouse |
| Brian C Shonesy, Walker P Parrish, Hala K Haddad, Jason R Stephenson, Rita Báldi, Rebecca J Bluett, Christian R Marks, Samuel W Centanni, Oakleigh M Folkes, Keeley Spiess, Shana M Augustin, Ken Mackie, David M Lovinger, Danny G Winder, Sachin Patel, Roger J Colbra. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biological psychiatry. vol 84. issue 4. 2019-10-04. PMID:29458998. |
deficits in signaling mediated by the endocannabinoid 2-arachidonoylglycerol (2-ag) have been reported in mouse models of autism spectrum disorder, but a causal role for striatal 2-ag deficiency in phenotypes relevant to autism spectrum disorder has not been explored. |
2019-10-04 |
2023-08-13 |
mouse |
| Vasco Deon Kid. Cannabinoids in the Treatment of Autism Spectrum Disorder: Demanding Data Before Using Fad Therapies. Pediatric neurology. vol 88. 2019-09-05. PMID:30318286. |
cannabinoids in the treatment of autism spectrum disorder: demanding data before using fad therapies. |
2019-09-05 |
2023-08-13 |
Not clear |
| Adi Aran, Maya Eylon, Moria Harel, Lola Polianski, Alina Nemirovski, Sigal Tepper, Aviad Schnapp, Hanoch Cassuto, Nadia Wattad, Joseph Ta. Lower circulating endocannabinoid levels in children with autism spectrum disorder. Molecular autism. vol 10. 2019-04-11. PMID:30728928. |
lower circulating endocannabinoid levels in children with autism spectrum disorder. |
2019-04-11 |
2023-08-13 |
human |
| Anna Lisa Brigida, Stephen Schultz, Mariana Cascone, Nicola Antonucci, Dario Siniscalc. Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations. International journal of molecular sciences. vol 18. issue 7. 2018-03-30. PMID:28671614. |
several studies highlight a key involvement of endocannabinoid (ec) system in autism pathophysiology. |
2018-03-30 |
2023-08-13 |
Not clear |
| Bhismadev Chakrabarti, Antonio Persico, Natalia Battista, Mauro Maccarron. Endocannabinoid Signaling in Autism. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26216231. |
endocannabinoid signaling in autism. |
2016-07-22 |
2023-08-13 |
human |