All Relations between Cognitive Dysfunction and hippocampus

Publication Sentence Publish Date Extraction Date Species
Yixuan Niu, Guoying Liao, Zhengjie Miao, Jinnan Xu, Yanyong Cheng, Fan Wang, Chuanyu Qi, Tiannan Chen, Yi Gao, Lei Zhang, Hong Jiang, Jia Ya. Role of Hippocampal Glutamatergic Synaptic Alterations in Sevoflurane-Induced Cognitive Dysfunction in Aged Mice. CNS neuroscience & therapeutics. vol 30. issue 10. 2024-10-29. PMID:39468399. role of hippocampal glutamatergic synaptic alterations in sevoflurane-induced cognitive dysfunction in aged mice. 2024-10-29 2024-10-31 mouse
Yixuan Niu, Guoying Liao, Zhengjie Miao, Jinnan Xu, Yanyong Cheng, Fan Wang, Chuanyu Qi, Tiannan Chen, Yi Gao, Lei Zhang, Hong Jiang, Jia Ya. Role of Hippocampal Glutamatergic Synaptic Alterations in Sevoflurane-Induced Cognitive Dysfunction in Aged Mice. CNS neuroscience & therapeutics. vol 30. issue 10. 2024-10-29. PMID:39468399. our study aims to analyze the differentially expressed genes (degs) in excitatory neurons and investigate the role of hippocampal glutamatergic synaptic alterations in sevoflurane-induced cognitive dysfunction in aged mice. 2024-10-29 2024-10-31 mouse
Bao-Wen Zhang, Ying Li, Xian-Juan Ko. [Resistance exercise regulates hippocampal microglia polarization through TREM2/NF-κB/STAT3 signal pathway to improve cognitive dysfunction in T2DM mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 5. 2024-10-29. PMID:39468808. [resistance exercise regulates hippocampal microglia polarization through trem2/nf-κb/stat3 signal pathway to improve cognitive dysfunction in t2dm mice]. 2024-10-29 2024-10-31 mouse
Qianqian Xu, Lihui Wang, Qiong Song, Shuai Chen, Kechen Du, Xiahong Teng, Chunlin Zo. Distinct Hippocampal Expression Profiles of lncRNAs in Obese Type 2 Diabetes Mice Exhibiting Cognitive Impairment. Neuromolecular medicine. vol 26. issue 1. 2024-10-29. PMID:39470862. collectively, these results revealed the differential hippocampal expression profiles of lncrnas in t2d mice with cognitive dysfunction, and the findings from this study provide new clues for exploring the potential roles of lncrnas in the pathogenesis of cognitive dysfunction in t2d. 2024-10-29 2024-11-02 mouse
Xian Guo, Borui Zhang, Yutong Chen, Zhi Jia, Xiaoyu Yuan, Li Zhang, Jie Liu, Yanan Li. Multifunctional mesoporous nanoselenium delivery of metformin breaks the vicious cycle of neuroinflammation and ROS, promotes microglia regulation and alleviates Alzheimer's disease. Colloids and surfaces. B, Biointerfaces. vol 245. 2024-10-24. PMID:39447310. collectively, in vivo experiments demonstrated that met@mse@tf significantly increased the number of neun-positive neurons in the hippocampus of ad mice, promoted neurovascular normalization in the brain, and improved cognitive dysfunction in ad transgenic ad mice. 2024-10-24 2024-10-28 mouse
Xuejiao Li, Zhongxiang Din. Cognitive dysfunction induced by cranial radiotherapy: mechanisms and therapeutic methods. Brain research bulletin. 2024-10-24. PMID:39447765. radiotherapy-induced cognitive dysfunction is associated with hippocampal injury, white matter damage and microvascular injury. 2024-10-24 2024-10-28 Not clear
Xin Yang, Haifeng Duan, Sirui Li, Jing Zhang, Liang Dong, Jingli Ding, Xinyi L. Yap1 alleviates sepsis associated encephalopathy by inhibiting hippocampus ferroptosis via maintaining mitochondrial dynamic homeostasis. Journal of cellular and molecular medicine. vol 28. issue 19. 2024-10-14. PMID:39400418. the results showed that yap1 conditional knockout in hippocampal caused lower survival in sae mice and cognitive dysfunction, as proved by morri's water maze (mwm) task, tail suspension test (tst), open field test (oft) and elevated plus maze test (epmt). 2024-10-14 2024-10-16 mouse
Wen Zhou, Zhijuan Tang, Yuan Li, Linfeng Lu, Tingting Bi, Libin Zha. Hippocampal PDHA1 gene knockout inhibits the Warburg Effect leading to cognitive dysfunction and attenuates the beneficial effects of ZiBuPiYin Recipe on cognition. Journal of ethnopharmacology. 2024-10-07. PMID:39374880. hippocampal pdha1 gene knockout inhibits the warburg effect leading to cognitive dysfunction and attenuates the beneficial effects of zibupiyin recipe on cognition. 2024-10-07 2024-10-10 Not clear
Jianguo Zhou, Lei Gong, Xiaoli Liu, Liping Chen, Zhou Yan. Mendelian randomization in Alzheimer's disease and mild cognitive impairment: Hippocampal volume associations. Neuroscience. 2024-10-05. PMID:39368607. this study investigates the association between cognitive dysfunction and hippocampal volumes in alzheimer's disease (ad) and mild cognitive impairment (mci) using mendelian randomization. 2024-10-05 2024-10-08 Not clear
Ebenezer O Ajiboye, Funmilayo Eniola Olopade, Omowumi Moromoke Femi-Akinlosotu, Matthew Temitayo Shokunb. Recovery of Learning and Memory Deficits Despite Persistent Pyknosis of the Hippocampal Pyramidal Neurons of Adult Hydrocephalic Mice. Journal of the West African College of Surgeons. vol 14. issue 4. 2024-09-24. PMID:39309375. the hippocampal alterations resulting from hydrocephalus are associated with various cognitive dysfunctions. 2024-09-24 2024-09-26 mouse
Shuang Tang, Wenli Xing, Jin Yan, Lin Wang, Zhao Li, Yingwen Wang, Nina Gu, Xiaochuan Su. TREM2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via PI3K/Akt signaling pathway. Brain research. 2024-09-13. PMID:39270995. trem2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via pi3k/akt signaling pathway. 2024-09-13 2024-09-16 mouse
Shuang Tang, Wenli Xing, Jin Yan, Lin Wang, Zhao Li, Yingwen Wang, Nina Gu, Xiaochuan Su. TREM2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via PI3K/Akt signaling pathway. Brain research. 2024-09-13. PMID:39270995. in conclusion, trem2 upregulation mitigates long-term cognitive dysfunction following sah by attenuating hippocampal neuroinflammation via the pi3k/akt signaling pathway. 2024-09-13 2024-09-16 mouse
Mackenzie M Spicer, Jianqi Yang, Daniel Fu, Alison N DeVore, Marisol Lauffer, Nilufer S Atasoy, Deniz Atasoy, Rory A Fishe. Regulator of G protein signaling 6 mediates exerciseinduced recovery of hippocampal neurogenesis, learning, and memory in a mouse model of Alzheimer's disease. Neural regeneration research. 2024-09-09. PMID:39248184. hippocampal neuronal loss causes cognitive dysfunction in alzheimer's disease. 2024-09-09 2024-09-11 mouse
Li-Li Lu, Li-Zhe Liu, Li Li, Yu-Yan Hu, Xiao-Hui Xian, Wen-Bin L. Sodium butyrate improves cognitive dysfunction in high-fat diet/ streptozotocin-induced type 2 diabetic mice by ameliorating hippocampal mitochondrial damage through regulating AMPK/PGC-1α pathway. Neuropharmacology. vol 261. 2024-09-05. PMID:39233201. sodium butyrate improves cognitive dysfunction in high-fat diet/ streptozotocin-induced type 2 diabetic mice by ameliorating hippocampal mitochondrial damage through regulating ampk/pgc-1α pathway. 2024-09-05 2024-09-08 mouse
Xin-Hao Jiao, Jie Wan, Wei-Feng Wu, Lin-Hui Ma, Chen Chen, Wei Dong, Yi-Qi Liu, Chun-Hui Jin, Ao Sun, Yue Zhou, Zi-Yi Li, Qiang Liu, Yu-Qing Wu, Cheng-Hua Zho. GLT-1 downregulation in hippocampal astrocytes induced by type 2 diabetes contributes to postoperative cognitive dysfunction in adult mice. CNS neuroscience & therapeutics. vol 30. issue 9. 2024-09-02. PMID:39218798. glt-1 downregulation in hippocampal astrocytes induced by type 2 diabetes contributes to postoperative cognitive dysfunction in adult mice. 2024-09-02 2024-09-04 mouse
Ezgi Kargi-Gemici, Aslıhan Şengelen, Yunus Aksüt, Onat Akyol, Selma Şengiz-Erhan, Mehmet Bay, Evren Önay-Uçar, Ayşin Selcan, Serdar Demirga. Cerium oxide nanoparticles (nanoceria) pretreatment attenuates cell death in the hippocampus and cognitive dysfunction due to repeated isoflurane anesthesia in newborn rats. Neurotoxicology. 2024-08-31. PMID:39216603. cerium oxide nanoparticles (nanoceria) pretreatment attenuates cell death in the hippocampus and cognitive dysfunction due to repeated isoflurane anesthesia in newborn rats. 2024-08-31 2024-09-04 rat
Mackenzie M Spicer, Jianqi Yang, Daniel Fu, Alison N DeVore, Marisol Lauffer, Nilufer S Atasoy, Deniz Atasoy, Rory A Fishe. RGS6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in an Alzheimer's mouse model. bioRxiv : the preprint server for biology. 2024-08-26. PMID:39185171. hippocampal neuronal loss causes cognitive dysfunction in alzheimer's disease (ad). 2024-08-26 2024-08-28 mouse
Yang Liu, Xiaokang Meng, Changfa Tang, Lan Zheng, Kun Tao, Wen Gu. Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice. Physiology & behavior. vol 286. 2024-08-25. PMID:39181380. microglia activation-induced neuroinflammation is a risk factor for cognitive dysfunction in the hippocampus during the early stages of neurodegenerative diseases. 2024-08-25 2024-08-28 mouse
Kian Mousavi-Nasab, Mohammad Amani, Sara Mostafalo. The Effect of Trientine on Alcl3-Induced Cognitive Dysfunction and Biochemical Changes in the Hippocampus of Rats. Drug research. 2024-08-22. PMID:39173674. the effect of trientine on alcl3-induced cognitive dysfunction and biochemical changes in the hippocampus of rats. 2024-08-22 2024-08-25 human
Haiming Yang, Ying Yuan, Ke Yang, Ning Wang, Xiao L. ELK4 ameliorates cognitive impairment and neuroinflammation induced by obstructive sleep apnea. Brain research bulletin. 2024-08-22. PMID:39173777. intermittent hypoxia (ih) in patients with obstructive sleep apnea (osa) syndrome elicited neuron injury (especially in the hippocampus and cortex), contributing to cognitive dysfunction. 2024-08-22 2024-08-25 mouse