All Relations between Dementia and microtubule-associated protein tau

Reference Sentence Publish Date Extraction Date Species
Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications vol 11 issue 1 2023 36597124 we conclude that the dg is differentially vulnerable to pathologic tau accumulation, raising intriguing questions about the structural integrity and functional significance of hippocampal circuits in neurodegenerative dementias. 2023-01-03 2023-01-05 Not clear
Aidong Yuan, Ralph A Nixo. Posttranscriptional regulation of neurofilament proteins and tau in health and disease. Brain research bulletin vol 192 issue 2022 36441047 neurofilament and tau proteins are neuron-specific cytoskeletal proteins that are enriched in axons, regulated by many of the same protein kinases, interact physically, and are the principal constituents of neurofibrillary lesions in major adult-onset dementias. 2022-11-28 2022-11-29 Not clear
Steffen Pockes, Michael A Walters, Karen H Ash. Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Translational research : the journal of laboratory and clinical medicine vol issue 2022 36343883 targeting caspase-2 interactions with tau in alzheimer's disease and related dementias. 2022-11-07 2022-11-15 Not clear
Steffen Pockes, Michael A Walters, Karen H Ash. Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Translational research : the journal of laboratory and clinical medicine vol issue 2022 36343883 targeting amyloid-\xce\xb2 plaques and tau tangles has failed to provide effective treatments for alzheimer's disease and related dementias (adrd). 2022-11-07 2022-11-15 Not clear
Ram\\xc3\\xb3n Mart\\xc3\\xadnez-M\\xc3\\xa1rmol, Christopher Small, Anmin Jiang, Tishila Palliyaguru, Tristan P Wallis, Rachel S Gormal, Jean-Baptiste Sibarita, J\\xc3\\xbcrgen G\\xc3\\xb6tz, Fr\\xc3\\xa9d\\xc3\\xa9ric A Meunie. Fyn nanoclustering requires switching to an open conformation and is enhanced by FTLD-Tau biomolecular condensates. Molecular psychiatry vol issue 2022 36258016 postsynaptic enrichment of fyn underpins synaptotoxicity in dementias such as alzheimer's disease and frontotemporal lobar degeneration with tau pathology (ftld-tau). 2022-10-18 2022-10-25 Not clear
Lenka Hromadkova, Mohammad Khursheed Siddiqi, He Liu, Jiri G Safa. Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer's Disease and Related Dementias. Cells vol 11 issue 19 2022 36230957 populations of tau conformers drive prion-like strain effects in alzheimer's disease and related dementias. 2022-10-14 2022-10-25 Not clear
Andrea Arighi, Marina Arcaro, Giorgio Giulio Fumagalli, Tiziana Carandini, Anna Margherita Pietroboni, Luca Sacchi, Chiara Fenoglio, Maria Serpente, Federica Sorrentino, Giovanni Isgr\\xc3\\xb2, Federico Turkheimer, Elio Scarpini, Daniela Galimbert. Aquaporin-4 cerebrospinal fluid levels are higher in neurodegenerative dementia: looking at glymphatic system dysregulation. Alzheimer's research & therapy vol 14 issue 1 2022 36115967 in this study, cerebrospinal fluid (csf) concentration of aqp4, amyloid-\xce\xb2, total tau and p-tau were determined in 103 csf samples from patients affected by neurodegenerative dementias (ad and ftd) or psychiatric diseases and 21 controls. 2022-09-17 2022-09-20 Not clear
Sophie Schmidt, Max Holzer, Thomas Arendt, Mandy Sonntag, Markus Morawsk. Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L- Biomolecules vol 12 issue 4 2022 35454094 tau protein modulates perineuronal extracellular matrix expression in the taup301l- tau mutations promote the formation of tau oligomers and filaments, which are neuropathological signs of several tau-associated dementias. 2022-04-23 2022-04-25 Not clear
Harun Muayad Said, Derya Kaya, Idil Yavuz, Fatma Sena Dost, Zekiye Sultan Altun, Ahmet Turan Isi. A Comparison of Cerebrospinal Fluid Beta-Amyloid and Tau in Idiopathic Normal Pressure Hydrocephalus and Neurodegenerative Dementias. Clinical interventions in aging vol 17 issue 2022 35431542 a comparison of cerebrospinal fluid beta-amyloid and tau in idiopathic normal pressure hydrocephalus and neurodegenerative dementias. 2022-04-18 2022-04-19 Not clear
Heidi G Standke, Allison Krau. Seed amplification and RT-QuIC assays to investigate protein seed structures and strains. Cell and tissue research vol issue 2022 35258712 first shown for prp prions and prion diseases, it is now recognized that self-propagating misfolded proteins occur broadly in neurodegenerative diseases and include amyloid-\xce\xb2 (a\xce\xb2) and tau in alzheimer's disease (ad), tau in chronic traumatic encephalopathy (cte), pick's disease (pid), corticobasal degeneration (cbd), and progressive supranuclear palsy (psp), and \xce\xb1-synuclein (\xce\xb1-syn) in parkinson's disease (pd) and lewy body dementias (lbd). 2022-03-08 2022-03-09 Not clear
Federico Verd. Tau proteins in blood as biomarkers of Alzheimer's disease and other proteinopathies. Journal of neural transmission (Vienna, Austria : 1996) vol issue 2022 35175385 thanks to recent technological advances, total and phosphorylated tau can now be quantified also on peripheral blood, and accumulating evidence shows that measurement of plasma phosphorylated tau species (p-tau181, p-tau217, and p-tau231) has high performances in discriminating ad patients from cognitively unimpaired subjects but also from patients with other dementias. 2022-02-17 2022-02-23 Not clear
Mahmoud B Maina, Laura J Bailey, Aidan J Doherty, Louise C Serpel. The Involvement of A\\xce\\xb242 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction. Frontiers in cellular neuroscience vol 12 issue 2020 30123109 alzheimer's disease (ad) is the most common form of dementia and is distinguished from other dementias by observation of extracellular amyloid-\xce\xb2 (a\xce\xb2) plaques and intracellular neurofibrillary tangles, comprised of fibrils of a\xce\xb2 and tau protein, respectively. 2022-01-29 2022-01-13 Not clear
Ahlam S Soliman, Andrew Umstead, Tessa Grabinski, Nicholas M Kanaan, Andy Lee, John Ryan, Jared Lamp, Irving E Veg. EFhd2 brain interactome reveals its association with different cellular and molecular processes. Journal of neurochemistry vol 159 issue 6 2021 34543436 we have shown that efhd2 interacts with tau protein, a key pathological hallmark in alzheimer's disease and related dementias. 2021-12-17 2022-01-13 Not clear
Paul A Yushkevich, M\\xc3\\xb3nica Mu\\xc3\\xb1oz L\\xc3\\xb3pez, Mar\\xc3\\xada Mercedes I\\xc3\\xb1iguez de Onzo\\xc3\\xb1o Martin, Ranjit Ittyerah, Sydney Lim, Sadhana Ravikumar, Madigan L Bedard, Stephen Pickup, Weixia Liu, Jiancong Wang, Ling Yu Hung, Jade Lasserve, Nicolas Vergnet, Long Xie, Mengjin Dong, Salena Cui, Lauren McCollum, John L Robinson, Theresa Schuck, Robin de Flores, Murray Grossman, M Dylan Tisdall, Karthik Prabhakaran, Gabor Mizsei, Sandhitsu R Das, Emilio Artacho-P\\xc3\\xa9rula, Mar\\xc4\\xb1'a Del Mar Arroyo Jim\\xc3\\xa9nez, Mar\\xc4\\xb1'a Pilar Marcos Raba, Francisco Javier Molina Romero, Sandra Cebada S\\xc3\\xa1nchez, Jos\\xc3\\xa9 Carlos Delgado Gonz\\xc3\\xa1lez, Carlos de la Rosa-Prieto, Marta C\\xc3\\xb3rcoles Parada, Edward B Lee, John Q Trojanowski, Daniel T Ohm, Laura E M Wisse, David A Wolk, David J Irwin, Ricardo Insaust. Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe. Brain : a journal of neurology vol 144 issue 9 2021 34259858 tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive decline in alzheimer's disease and related dementias. 2021-12-09 2022-01-13 Not clear
Steven Y Yap, Barbara Frias, Melissa C Wren, Michael Sch\\xc3\\xb6ll, Nick C Fox, Erik \\xc3\\x85rstad, Tammaryn Lashley, Kerstin Sande. Discriminatory ability of next-generation tau PET tracers for Alzheimer's disease. Brain : a journal of neurology vol 144 issue 8 2021 33742656 a next generation of tau pet tracers for the imaging of alzheimer's disease and other dementias has recently been developed. 2021-12-08 2022-01-13 Not clear
James R Hall, Melissa Petersen, Leigh Johnson, Sid E O'Bryan. Plasma Total Tau and Neurobehavioral Symptoms of Cognitive Decline in Cognitively Normal Older Adults. Frontiers in psychology vol 12 issue 2021 34803857 tau pathology is a key feature of a number of dementias. 2021-11-23 2022-01-13 Not clear
Brian Spencer, Robert A Rissman, Cassia Overk, Eliezer Maslia. Novel Brain-Penetrating Single Chain Antibodies Directed Against 3RTau for the Treatment of Alzheimer's Disease and Related Dementias. Methods in molecular biology (Clifton, N.J.) vol 2383 issue 2021 34766306 these single chain antibodies are modified by the addition of a fragment of the apob protein to facilitate trafficking into the brain, once in the cns these antibody fragments recognize tau with potential value for the treatment of ad and related dementias. 2021-11-19 2022-01-13 Not clear
Benjamin Combs, Kyle R Christensen, Collin Richards, Andrew Kneynsberg, Rebecca L Mueller, Sarah L Morris, Gerardo A Morfini, Scott T Brady, Nicholas M Kanaa. Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1\\xce\\xb3-Dependent Mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 41 issue 45 2021 34607969 inherited mutations in tau cause early onset frontotemporal lobar dementias (ftld-tau) and are commonly used to model mechanisms of tau toxicity in tauopathies. 2021-11-13 2022-01-13 Not clear
Kai Sin Chin, Nawaf Yassi, Leonid Churilov, Colin Louis Masters, Rosie Watso. Prevalence and clinical associations of tau in Lewy body dementias: A systematic review and meta-analysis. Parkinsonism & related disorders vol 80 issue 2021 33260030 prevalence and clinical associations of tau in lewy body dementias: a systematic review and meta-analysis. 2021-10-21 2022-01-13 Not clear
Kai Sin Chin, Nawaf Yassi, Leonid Churilov, Colin Louis Masters, Rosie Watso. Prevalence and clinical associations of tau in Lewy body dementias: A systematic review and meta-analysis. Parkinsonism & related disorders vol 80 issue 2021 33260030 alzheimer's disease neuropathologies (amyloid-\xce\xb2 and tau) frequently co-exist to varying degrees in lewy body dementias (lbd), which include dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd). 2021-10-21 2022-01-13 Not clear
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