All Relations between Depression and central grey

Publication Sentence Publish Date Extraction Date Species
Xingfeng Liu, Jingxin He, Wei Jiang, Song Wen, Zhi Xia. The roles of periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the mechanisms of thermal hypersensitivity and depression in mice. The journal of pain. 2023-02-16. PMID:36796500. collectively these results demonstrated the specific role of ventrolateral periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the regulation of pain and depression comorbidity in mice. 2023-02-16 2023-08-14 mouse
Xingfeng Liu, Jingxin He, Wei Jiang, Song Wen, Zhi Xia. The roles of periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the mechanisms of thermal hypersensitivity and depression in mice. The journal of pain. 2023-02-16. PMID:36796500. perspective: the current study provides insights into the complex mechanisms underlying thermal hypersensitivity induced by depression, and the findings suggest that pharmacological and chemogenetic modulation of dopaminergic systems in the ventrolateral periaqueductal gray and dorsal raphe nucleus may be a promising therapeutic strategy to simultaneously mitigate pain and depression. 2023-02-16 2023-08-14 mouse
Xingfeng Liu, Jingxin He, Wei Jiang, Song Wen, Zhi Xia. The roles of periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the mechanisms of thermal hypersensitivity and depression in mice. The journal of pain. 2023-02-16. PMID:36796500. the roles of periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the mechanisms of thermal hypersensitivity and depression in mice. 2023-02-16 2023-08-14 mouse
Carl L Faingold, Hua-Jun Fen. A unified hypothesis of SUDEP: Seizure-induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the periaqueductal gray. Epilepsia. 2023-01-30. PMID:36715572. a unified hypothesis of sudep: seizure-induced respiratory depression induced by adenosine may lead to sudep but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the periaqueductal gray. 2023-01-30 2023-08-14 human
Carlos Silva, Neil McNaughto. Are periaqueductal gray and dorsal raphe the foundation of appetitive and aversive control? A comprehensive review. Progress in neurobiology. vol 177. 2020-04-29. PMID:30786258. we provide a comprehensive functional view of the periaqueductal gray, going beyond simple panic and escape to integrate data on fear, anxiety, and depression. 2020-04-29 2023-08-13 Not clear
Yu-Cheng Ho, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Dylan Chou, Yat-Pang Chau, Gin-Den Chen, Hsien-Yu Pen. Periaqueductal Gray Glutamatergic Transmission Governs Chronic Stress-Induced Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 2. 2018-07-30. PMID:28853438. periaqueductal gray glutamatergic transmission governs chronic stress-induced depression. 2018-07-30 2023-08-13 Not clear
Giannina Descalzi, Vasiliki Mitsi, Immanuel Purushothaman, Sevasti Gaspari, Kleopatra Avrampou, Yong-Hwee Eddie Loh, Li Shen, Venetia Zachario. Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression. Science signaling. vol 10. issue 471. 2017-11-28. PMID:28325815. using two mouse models of neuropathic pain and depression [spared nerve injury (sni) and chronic unpredictable stress (cus)], we performed next-generation rna sequencing and pathway analysis to monitor changes in gene expression in the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the periaqueductal gray (pag). 2017-11-28 2023-08-13 mouse
Volodymyr Borysovych Bogdanov, Olena Viktorivna Bogdanova, Arnaud Lombard, Virginie Chauvel, Sylvie Multon, Larysa Ivanivna Kot, Mykola Yukhymovych Makarchuk, Jean Schoene. Cortical spreading depression decreases Fos expression in rat periaqueductal gray matter. Neuroscience letters. vol 585. 2015-08-19. PMID:25445358. cortical spreading depression decreases fos expression in rat periaqueductal gray matter. 2015-08-19 2023-08-13 rat
Jeyce W Quintino-dos-Santos, Cláudia J T Müller, Alexandre M C Santos, Sérgio Tufik, Caroline A Rosa, Luiz C Schenber. Long-lasting marked inhibition of periaqueductal gray-evoked defensive behaviors in inescapably-shocked rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24188077. accordingly, here we examined the late effects of uncontrollable stress, a presumptive model of depression and/or traumatic disorder, on panic-like behaviors evoked by electrical stimulation of the dorsal periaqueductal gray (dpag). 2014-09-03 2023-08-12 human
Jing-Shi Tang, Chao-Ling Qu, Fu-Quan Hu. The thalamic nucleus submedius and ventrolateral orbital cortex are involved in nociceptive modulation: a novel pain modulation pathway. Progress in neurobiology. vol 89. issue 4. 2010-02-12. PMID:19819292. the sm, ventrolateral orbital cortex (vlo) and the periaqueductal gray (pag) constitute a pain modulatory pathway, activation of which leads to activation of the pag-brainstem descending inhibitory system and depression of the nociceptive inputs in the spinal cord and trigeminal nucleus. 2010-02-12 2023-08-12 Not clear
Marcelo E Bigal, Richard B Lipto. Concepts and mechanisms of migraine chronification. Headache. vol 48. issue 1. 2008-05-02. PMID:18184280. progression may be a consequence of the mechanisms that generate the migraine attacks (eg, cortical spreading depression) or it may be a function of the activations generated by the attacks (eg, lesions in the periaqueductal gray area), a hypothesis supported by the increase in lesions with attack frequency. 2008-05-02 2023-08-12 Not clear
b' Henriette Husum, Gitta W\\xc3\\xb6rtwein, Weronika Andersson, Tom G Bolwig, Aleksander A Math\\xc3\\xa. Gene-environment interaction affects substance P and neurokinin A in the entorhinal cortex and periaqueductal grey in a genetic animal model of depression: implications for the pathophysiology of depression. The international journal of neuropsychopharmacology. vol 11. issue 1. 2008-04-15. PMID:17477887.' gene-environment interaction affects substance p and neurokinin a in the entorhinal cortex and periaqueductal grey in a genetic animal model of depression: implications for the pathophysiology of depression. 2008-04-15 2023-08-12 rat
Roger A Kroes, Jeffrey Burgdorf, Nigel J Otto, Jaak Panksepp, Joseph R Moska. Social defeat, a paradigm of depression in rats that elicits 22-kHz vocalizations, preferentially activates the cholinergic signaling pathway in the periaqueductal gray. Behavioural brain research. vol 182. issue 2. 2007-10-26. PMID:17452055. social defeat, a paradigm of depression in rats that elicits 22-khz vocalizations, preferentially activates the cholinergic signaling pathway in the periaqueductal gray. 2007-10-26 2023-08-12 rat
R Aboufatima, A Chait, A Dalal, R de Beaurepair. Calcitonin microinjection into the periaqueductal gray impairs contextual fear conditioning in the rat. Neuroscience letters. vol 275. issue 2. 1999-12-16. PMID:10568509. as depression is characterized by context-related anxiety, behavioral inhibition and alterations in memory processing, we tested the effects of microinjections of salmon calcitonin into the periaqueductal gray matter (pag) on contextual fear conditioning in the rat. 1999-12-16 2023-08-12 rat
D Q Xiao, J S Tang, B Yuan, H Ji. Inhibitory effects of 5-hydroxytryptamine microinjection into thalamic nucleus submedius on rat tail flick reflex are mediated by 5-HT2 receptors. Neuroscience letters. vol 260. issue 2. 1999-06-18. PMID:10025705. our previous findings indicated that electrical or chemical activation of the thalamic nucleus submedius (sm) produced significant antinociceptive effects and that these effect were blocked by lesion or depression of the ventrolateral orbital cortex (vlo) or the periaqueductal gray (pag) suggesting a role of the sm in modulation of nociception. 1999-06-18 2023-08-12 rat
V C Raos, H E Savak. Functional anatomy of the thalamic reticular nucleus as revealed with the [14C]deoxyglucose method following electrical stimulation and electrolytic lesion. Neuroscience. vol 68. issue 2. 1995-12-12. PMID:7477941. unilateral electrical stimulation of the thalamic reticular nucleus induced the following changes in glucose utilization: (i) local enhancement of metabolic activity within the stimulated thalamic reticular nucleus, (ii) increase in glucose consumption in the ipsilateral thalamic mediodorsal, centrolateral, ventromedial and ventrolateral nuclei, as well as in the nucleus accumbens, (iii) bilateral depression of metabolism in the locus coeruleus, periaqueductal gray, ventral tegmental area, and medial habenula, as well as contralateral metabolic depression in the substantia nigra reticulata, compacta and in the ventral pallidum. 1995-12-12 2023-08-12 rat
V C Raos, C R Dermon, H E Savak. Functional anatomy of the thalamic centrolateral nucleus as revealed with the [14C]deoxyglucose method following electrical stimulation and electrolytic lesion. Neuroscience. vol 68. issue 2. 1995-12-12. PMID:7477942. the metabolic depression measured in the medulla and pons (medullary and pontine reticular formation, periaqueductal gray, locus coeruleus, dorsal tegmental, cuneiformis, raphe and pedunculopontine tegmental nuclei), the cerebellum (molecular and granular layers of the cerebellar cortex, interpositus and dentate nuclei), the mesencephalon (substantia nigra reticulata, ventral tegmental area and deep layers of the superior colliculus), the diencephalon (medial habenula, parafascicular, ventrobasal complex, centromedial and reticular thalamic nuclei), the rhinencephalon (dentate gyrus and septum), the basal ganglia (ventral pallidum, globus pallidus, entopeduncular and accumbens nuclei) and the cerebral cortex (superficial and deep layers of the frontal and parietal cortex, deep layers of the forelimb cortex) were bilateral. 1995-12-12 2023-08-12 rat
V C Raos, C R Dermon, H E Savak. Functional anatomy of the thalamic centrolateral nucleus as revealed with the [14C]deoxyglucose method following electrical stimulation and electrolytic lesion. Neuroscience. vol 68. issue 2. 1995-12-12. PMID:7477942. unilateral electrical stimulation of the centrolateral nucleus induced: (i) local increase in metabolic activity within the stimulated centrolateral nucleus and the ipsilateral thalamic mediodorsal nucleus, (ii) metabolic depression in all layers of the ipsilateral frontal cortex, (iii) bilateral increase in glucose consumption within the periaqueductal gray, pedunculopontine nucleus, and pontine reticular formation, and (iv) contralateral metabolic activation in the deep cerebellar nuclei. 1995-12-12 2023-08-12 rat
M M Morgan, M M Heinricher, H L Field. Circuitry linking opioid-sensitive nociceptive modulatory systems in periaqueductal gray and spinal cord with rostral ventromedial medulla. Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1579215. previous studies have shown that the spontaneous and tail-flick-related firing of on-cells is invariably depressed when morphine is given systemically in doses demonstrated to inhibit the tail-flick reflex, and that a similar depression of this activity is produced when morphine is applied directly in the periaqueductal gray or intrathecal space. 1992-06-05 2023-08-11 rat
M V Karpukhina, A P Gokin, N E Tikhomiro. [The neurochemical mechanisms of the inhibitory influences of stimulation of the central gray substance on the high-threshold reflex activity of the reticular formation]. Neirofiziologiia = Neurophysiology. vol 23. issue 4. 1991-11-20. PMID:1681433. influences of bulbar microinjections of some neuromodulator antagonists (methysergide, haloperidol, naloxone) on depression dynamics of spino-bulbo-spinal (sbs) reflex from the periaqueductal grey (pag) stimulation were studied in chloralose anesthetized rats. 1991-11-20 2023-08-11 rat