| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Andrijana Stanisavljevi\\xc4\\x87 Ili\\xc4\\x87, Sne\\xc5\\xbeana \\xc4\\x90or\\xc4\\x91evi\\xc4\\x87, Drago\\xc5\\xa1 Inta, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Olanzapine Effects on Parvalbumin/GAD67 Cell Numbers in Layers/Subregions of Dorsal Hippocampus of Chronically Socially Isolated Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139008.' |
we determined the effect of olz on pv-positive (+) and glutamate decarboxylase 67 (gad67) + cell numbers in the layers of dorsal hippocampus (dhipp) cornu ammonis (ca1-ca3) and dentate gyrus (dg) subregions in rats exposed to chronic social isolation (csis), which is an animal model of depression. |
2023-12-23 |
2023-12-25 |
rat |
| Xueru Xu, Ri Chen, Youfen Yu, Jing Yang, Chun Lin, Rongguo Li. Pulsed radiofrequency on DRG inhibits hippocampal neuroinflammation by regulating spinal GRK2/p38 expression and enhances spinal autophagy to reduce pain and depression in male rats with spared nerve injury. International immunopharmacology. vol 127. 2023-12-23. PMID:38141406. |
pulsed radiofrequency on drg inhibits hippocampal neuroinflammation by regulating spinal grk2/p38 expression and enhances spinal autophagy to reduce pain and depression in male rats with spared nerve injury. |
2023-12-23 |
2023-12-25 |
rat |
| Xueru Xu, Ri Chen, Youfen Yu, Jing Yang, Chun Lin, Rongguo Li. Pulsed radiofrequency on DRG inhibits hippocampal neuroinflammation by regulating spinal GRK2/p38 expression and enhances spinal autophagy to reduce pain and depression in male rats with spared nerve injury. International immunopharmacology. vol 127. 2023-12-23. PMID:38141406. |
however, whether grk2/p38mapk and autophagic flux in the scdh and hippocampal neuroinflammation are involved in nep and depression comorbidity has not been determined. |
2023-12-23 |
2023-12-25 |
rat |
| Raegan Mazurka, Simone Cunningham, Stefanie Hassel, Jane A Foster, Nikita Nogovitsyn, Laura M Fiori, Stephen C Strother, Stephen R Arnott, Benicio N Frey, Raymond W Lam, Glenda M MacQueen, Roumen V Milev, Susan Rotzinger, Gustavo Turecki, Sidney H Kennedy, Kate L Harknes. Relation of hippocampal volume and SGK1 gene expression to treatment remission in major depression is moderated by childhood maltreatment: A CAN-BIND-1 report. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 78. 2023-12-21. PMID:38128154. |
relation of hippocampal volume and sgk1 gene expression to treatment remission in major depression is moderated by childhood maltreatment: a can-bind-1 report. |
2023-12-21 |
2023-12-24 |
human |
| Raegan Mazurka, Simone Cunningham, Stefanie Hassel, Jane A Foster, Nikita Nogovitsyn, Laura M Fiori, Stephen C Strother, Stephen R Arnott, Benicio N Frey, Raymond W Lam, Glenda M MacQueen, Roumen V Milev, Susan Rotzinger, Gustavo Turecki, Sidney H Kennedy, Kate L Harknes. Relation of hippocampal volume and SGK1 gene expression to treatment remission in major depression is moderated by childhood maltreatment: A CAN-BIND-1 report. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 78. 2023-12-21. PMID:38128154. |
further, we examined whether baseline levels of sgk1 and hippocampal volume, or changes in these markers over the course of antidepressant treatment, would predict treatment outcomes in adults with major depression [mdd]. |
2023-12-21 |
2023-12-24 |
human |
| Raegan Mazurka, Simone Cunningham, Stefanie Hassel, Jane A Foster, Nikita Nogovitsyn, Laura M Fiori, Stephen C Strother, Stephen R Arnott, Benicio N Frey, Raymond W Lam, Glenda M MacQueen, Roumen V Milev, Susan Rotzinger, Gustavo Turecki, Sidney H Kennedy, Kate L Harknes. Relation of hippocampal volume and SGK1 gene expression to treatment remission in major depression is moderated by childhood maltreatment: A CAN-BIND-1 report. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 78. 2023-12-21. PMID:38128154. |
we assessed sgk1 mrna expression from peripheral blood, and left and right hippocampal volume at baseline, as well as change in these markers over the first 8 weeks of a 16-week open-label trial of escitalopram as part of the canadian biomarker integration network in depression program (mdd [n = 161] and healthy comparison participants [n = 91]). |
2023-12-21 |
2023-12-24 |
human |
| Lucas Ronat, Alexandru Hanganu, Daphné Chylinski, Maxime Van Egroo, Justinas Narbutas, Gabriel Besson, Vincenzo Muto, Christina Schmidt, Mohamed Ali Bahri, Christophe Phillips, Eric Salmon, Pierre Maquet, Gilles Vandewalle, Fabienne Collette, Christine Basti. Prediction of cognitive decline in healthy aging based on neuropsychiatric symptoms and PET-biomarkers of Alzheimer's disease. Journal of neurology. 2023-12-20. PMID:38114820. |
moreover, depression together with prefrontal and hippocampal tau burden were associated with a decline in memory. |
2023-12-20 |
2023-12-23 |
human |
| Computational And Mathematical Methods In Medicin. Retracted: Effects of miR-124-3p Silencing on Neuronal Damage in the Hippocampus of Depression Rats by Regulating STAT3 Gene. Computational and mathematical methods in medicine. vol 2023. 2023-12-14. PMID:38094391. |
retracted: effects of mir-124-3p silencing on neuronal damage in the hippocampus of depression rats by regulating stat3 gene. |
2023-12-14 |
2023-12-17 |
rat |
| Yan Luo, Yan Wang, Feng Qiu, Guanghan Hou, Jian Liu, Hui Yang, Mei Wu, Xuanqi Dong, Dongwei Guo, Ziyan Zhong, Xi Zhang, Jinwen Ge, Pan Men. Ablated Sonic Hedgehog Signaling in the Dentate Gyrus of the Dorsal and Ventral Hippocampus Impairs Hippocampal-Dependent Memory Tasks and Emotion in a Rat Model of Depression. Molecular neurobiology. 2023-12-12. PMID:38087166. |
ablated sonic hedgehog signaling in the dentate gyrus of the dorsal and ventral hippocampus impairs hippocampal-dependent memory tasks and emotion in a rat model of depression. |
2023-12-12 |
2023-12-17 |
rat |
| Yan Luo, Yan Wang, Feng Qiu, Guanghan Hou, Jian Liu, Hui Yang, Mei Wu, Xuanqi Dong, Dongwei Guo, Ziyan Zhong, Xi Zhang, Jinwen Ge, Pan Men. Ablated Sonic Hedgehog Signaling in the Dentate Gyrus of the Dorsal and Ventral Hippocampus Impairs Hippocampal-Dependent Memory Tasks and Emotion in a Rat Model of Depression. Molecular neurobiology. 2023-12-12. PMID:38087166. |
specific memory processes and emotional aberrations in depression can be attributed to the different dorsal-ventral regions of the hippocampus. |
2023-12-12 |
2023-12-17 |
rat |
| Batoul Mirbolouk, Behrooz Khakpour-Taleghani, Mohammad Rostampour, Adele Jafari, Kambiz Rohampou. Enhanced low-gamma band power in the hippocampus and prefrontal cortex in a rat model of depression is reversed by orexin-1 receptor antagonism. IBRO neuroscience reports. vol 15. 2023-12-11. PMID:38074161. |
enhanced low-gamma band power in the hippocampus and prefrontal cortex in a rat model of depression is reversed by orexin-1 receptor antagonism. |
2023-12-11 |
2023-12-17 |
rat |
| Batoul Mirbolouk, Behrooz Khakpour-Taleghani, Mohammad Rostampour, Adele Jafari, Kambiz Rohampou. Enhanced low-gamma band power in the hippocampus and prefrontal cortex in a rat model of depression is reversed by orexin-1 receptor antagonism. IBRO neuroscience reports. vol 15. 2023-12-11. PMID:38074161. |
the purpose of this study is to determine whether orexin-1 receptor antagonists have an impact on changes in brain oscillations in the hippocampus and prefrontal cortex in a rat model of depression. |
2023-12-11 |
2023-12-17 |
rat |
| Kaige Liu, Yue Qu, Bozhi Li, Ningxi Zeng, Gaolei Yao, Xiaofeng Wu, Hanfang Xu, Can Yan, Lili W. GRP94 in cerebrospinal fluid may contribute to a potential biomarker of depression: Based on proteomics. Journal of psychiatric research. vol 169. 2023-12-11. PMID:38081093. |
the present study was designed to investigate potential biomarkers of depression and targets of antidepressants from the perspective of hippocampal endoplasmic reticulum stress (ers) based on cerebrospinal fluid (csf) proteomics. |
2023-12-11 |
2023-12-17 |
rat |
| Jiuseng Zeng, Zhiqiang Xie, Li Chen, Xi Peng, Fei Luan, Jingwen Hu, Hongxiao Xie, Rong Liu, Nan Zen. Rosmarinic acid alleviate CORT-induced depressive-like behavior by promoting neurogenesis and regulating BDNF/TrkB/PI3K signaling axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-12-09. PMID:38070249. |
taken together, ra exerted antidepressant activities by modulating the hippocampal glucocorticoid signaling and hippocampal neurogenesis, which related to the bdnf/trkb/pi3k signaling axis regulating gr nuclear translocation, provide evidence for the application of ra as a candidate for depression. |
2023-12-09 |
2023-12-17 |
mouse |
| Minji Kim, Minseok Yoon, Suengmok Cho, Changho Lee, Min Young U. γ-Oryzanol Ameliorates Depressive Behavior in Ovariectomized Mice by Regulating Hippocampal Nitric Oxide Synthase: A Potential Therapy for Menopausal Depression. Molecular nutrition & food research. 2023-12-06. PMID:38054627. |
γ-oryzanol ameliorates depressive behavior in ovariectomized mice by regulating hippocampal nitric oxide synthase: a potential therapy for menopausal depression. |
2023-12-06 |
2023-12-10 |
mouse |
| Wenrong Wen, Jingsheng Zhou, Chang'an Zhan, Jun Wan. Microglia as a Game Changer in Epilepsy Comorbid Depression. Molecular neurobiology. 2023-12-04. PMID:38048030. |
activated microglia released cytokines like il-6 and il-1β, orchestrating neuroinflammation especially in the hippocampus, worsening both depression and epilepsy. |
2023-12-04 |
2023-12-10 |
Not clear |
| Hamed Alizadeh Pahlavan. Possible role of exercise therapy on depression: effector neurotransmitters as key players. Behavioural brain research. 2023-12-04. PMID:38048912. |
in addition, exercise-induced orexin and npy can increase hippocampal neurogenesis and relieve depression. |
2023-12-04 |
2023-12-10 |
Not clear |
| Megan Dutton, Amanda Boyes, Adem T Can, Abdalla Z Mohamed, Maryam Hajishafiee, Zack Y Shan, Jim Lagopoulos, Daniel F Hermen. Hippocampal subfield volumes predict treatment response to oral ketamine in people with suicidality. Journal of psychiatric research. vol 169. 2023-12-02. PMID:38042058. |
ongoing stress results in hippocampal neuro-structural alterations which produce pathological consequences, including depression and suicidality. |
2023-12-02 |
2023-12-10 |
human |
| Sen Zhou, Yang Liu, Binbin Xue, Peigen Yua. Low-dose Esketamine suppresses NLRP3-mediated apoptotic and pyroptotic cell death in microglial cells to ameliorate LPS-induced depression via ablating GSK-3β. Behavioural brain research. vol 459. 2023-11-30. PMID:38029844. |
then, the following experiments verified that low-dose esketamine treatment decreased the expression levels of il-6, tnf-α and il-18 to restrain cellular inflammation, downregulated nlrp3, cleaved caspase-1, il-1β and gsdmd-n to hamper pyroptotic cell death, and inhibited cleaved caspase-3 and bax, but upregulated bcl-2 to restrict apoptotic cell death in the lps-treated mice hippocampus tissues and mouse microglial cells, leading to the suppression of depression development. |
2023-11-30 |
2023-12-10 |
mouse |
| Anbiao Wu, Jiyan Zhan. Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. Journal of neuroinflammation. vol 20. issue 1. 2023-11-28. PMID:38012702. |
neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. |
2023-11-28 |
2023-11-29 |
Not clear |