| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patrick N Stoney, Peter McCaffer. A Vitamin on the Mind: New Discoveries on Control of the Brain by Vitamin A. World review of nutrition and dietetics. vol 115. 2017-05-18. PMID:27198572. |
the effects of vitamin a deficiency on the hypothalamus may lead to depression of appetite and growth. |
2017-05-18 |
2023-08-13 |
human |
| Chenglong Rao, Haiyang Shi, Chanjuan Zhou, Dan Zhu, Mingjun Zhao, Ziye Wang, Yongtao Yang, Jin Chen, Li Liao, Jianyong Tang, You Wu, Jian Zhou, Ke Cheng, Peng Xi. Hypothalamic Proteomic Analysis Reveals Dysregulation of Glutamate Balance and Energy Metabolism in a Mouse Model of Chronic Mild Stress-Induced Depression. Neurochemical research. vol 41. issue 9. 2017-04-17. PMID:27230881. |
the aim of our study was to examine possible alterations in hypothalamus protein expression in a model of depression using proteomic analysis. |
2017-04-17 |
2023-08-13 |
mouse |
| Chenglong Rao, Haiyang Shi, Chanjuan Zhou, Dan Zhu, Mingjun Zhao, Ziye Wang, Yongtao Yang, Jin Chen, Li Liao, Jianyong Tang, You Wu, Jian Zhou, Ke Cheng, Peng Xi. Hypothalamic Proteomic Analysis Reveals Dysregulation of Glutamate Balance and Energy Metabolism in a Mouse Model of Chronic Mild Stress-Induced Depression. Neurochemical research. vol 41. issue 9. 2017-04-17. PMID:27230881. |
our results demonstrated that cums mice exhibited a dramatic protein change both in glutamate metabolism and energy mobilization, which may shed some light on the role of the hypothalamus in the pathology of stress-induced depression. |
2017-04-17 |
2023-08-13 |
mouse |
| T Matitaishvili, T Domianidze, G Burdjanadze, D Nadareishvili, M Khananashvil. INFORMATIONAL STRESS AS A DEPRESSION INDUCING FACTOR (EXPERIMENTAL STUDY). Georgian medical news. issue 262. 2017-04-10. PMID:28252439. |
under behavioral depression background, sharp increase of serotonin concentration in hypothalamus has been revealed which is caused by the peculiarities of stress model (by uncontrollable stressor. |
2017-04-10 |
2023-08-13 |
rat |
| A D Kruchinina, S S Gamzin, M T Tengi. Effects of Single Administration of Bupropion on Carboxypeptidase E Activity in Structures of Rat Brain. Bulletin of experimental biology and medicine. vol 161. issue 6. 2017-02-09. PMID:27783296. |
activation of the enzyme in the medulla oblongata, hypothalamus, and hippocampus observed in 72 h after bupropion administration probably leads to enhanced synthesis and secretion of regulatory peptides (reduced during stress and depression) and stimulation of neurogenesis. |
2017-02-09 |
2023-08-13 |
rat |
| Shuei Sugama, Yoshihiko Kakinum. Loss of dopaminergic neurons occurs in the ventral tegmental area and hypothalamus of rats following chronic stress: Possible pathogenetic loci for depression involved in Parkinson's disease. Neuroscience research. vol 111. 2016-12-29. PMID:27142317. |
loss of dopaminergic neurons occurs in the ventral tegmental area and hypothalamus of rats following chronic stress: possible pathogenetic loci for depression involved in parkinson's disease. |
2016-12-29 |
2023-08-13 |
rat |
| Mateusz Kucharczyk, Anna Kurek, Jan Detka, Joanna Slusarczyk, Mariusz Papp, Katarzyna Tota, Agnieszka Basta-Kaim, Marta Kubera, Wladyslaw Lason, Bogusława Budziszewsk. Chronic mild stress influences nerve growth factor through a matrix metalloproteinase-dependent mechanism. Psychoneuroendocrinology. vol 66. 2016-12-23. PMID:26771945. |
the hypothalamus is a critical coordinator of stress and the metabolic response; therefore, disruptions in this structure may be a significant cause of the hormonal and metabolic disturbances observed in depression. |
2016-12-23 |
2023-08-13 |
rat |
| Tapan Kavi, Donna Molaie, Michael Nurok, Axel Rosengart, Shouri Lahir. Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review. Case reports in critical care. vol 2016. 2016-08-16. PMID:27529037. |
the mechanism involves direct myocardial depression and inhibition of autonomic neuroanatomical structures including the medulla and hypothalamus. |
2016-08-16 |
2023-08-13 |
Not clear |
| Joëlle Chabry, Sarah Nicolas, Julie Cazareth, Emilie Murris, Alice Guyon, Nicolas Glaichenhaus, Catherine Heurteaux, Agnès Petit-Paite. Enriched environment decreases microglia and brain macrophages inflammatory phenotypes through adiponectin-dependent mechanisms: Relevance to depressive-like behavior. Brain, behavior, and immunity. vol 50. 2016-08-15. PMID:26209808. |
here, we show that in a murine model of depression induced by chronic corticosterone administration, the hippocampus and the hypothalamus display increased levels of inflammatory cytokines mrna, which is reversed by ee housing. |
2016-08-15 |
2023-08-13 |
mouse |
| Lihua Yao, Jianxin Chen, Hexiang Chen, Dan Xiang, Can Yang, Ling Xiao, Wanhong Liu, Huiling Wang, Gaohua Wang, Fan Zhu, Zhongchun Li. Hypothalamic gastrin-releasing peptide receptor mediates an antidepressant-like effect in a mouse model of stress. American journal of translational research. vol 8. issue 7. 2016-08-10. PMID:27508030. |
after fluoxetine treatment was administered, the animals' depression symptoms were alleviated, and these behavioral alterations were accompanied by specific changes in mrna and protein expression of grpr in the hypothalamus. |
2016-08-10 |
2023-08-13 |
mouse |
| Xianglan Wang, Jiong Tao, Zhiyong Zhong, Sha Liu, Zili Han, Jinbei Zhang, Lingjiang L. [The resting-state functional connectivity of the hypothalamus and its relationships with gonadal steroid hormones and depression symptoms in perimenopausal women]. Zhonghua yi xue za zhi. vol 95. issue 39. 2016-04-07. PMID:26814116. |
[the resting-state functional connectivity of the hypothalamus and its relationships with gonadal steroid hormones and depression symptoms in perimenopausal women]. |
2016-04-07 |
2023-08-13 |
Not clear |
| Xianglan Wang, Jiong Tao, Zhiyong Zhong, Sha Liu, Zili Han, Jinbei Zhang, Lingjiang L. [The resting-state functional connectivity of the hypothalamus and its relationships with gonadal steroid hormones and depression symptoms in perimenopausal women]. Zhonghua yi xue za zhi. vol 95. issue 39. 2016-04-07. PMID:26814116. |
this study aimed to investigate the resting-state functional connectivity of the hypothalamus and its relationships with gonadal steroid hormones and depression symptoms in perimenopausal women. |
2016-04-07 |
2023-08-13 |
Not clear |
| W J Hoogendijk, G Meynen, P Eikelenboom, D F Swaa. Brain alterations in depression. Acta neuropsychiatrica. vol 12. issue 2. 2016-03-16. PMID:26976759. |
we did find, however, that the number of corticotropin-releasing hormone-, vasopressin- and oxytocin expressing neurons, the number of corticotropin-releasing hormone neurons co-expressing vasopressin and the amount of corticotropin-releasing hormone -mrna in idiopathic depression were strongly increased in the paraventricular nucleus of the hypothalamus. |
2016-03-16 |
2023-08-13 |
Not clear |
| Greg Dusso. ASICs as therapeutic targets for migraine. Neuropharmacology. vol 94. 2016-03-02. PMID:25582295. |
several processes are currently thought to contribute to migraine including altered activity in the hypothalamus, cortical-spreading depression (csd), and afferent sensory input from the cranial meninges. |
2016-03-02 |
2023-08-13 |
human |
| Keith Sudheimer, Jennifer Keller, Rowena Gomez, Lakshika Tennakoon, Allan Reiss, Amy Garrett, Heather Kenna, Ruth O'Hara, Alan F Schatzber. Decreased hypothalamic functional connectivity with subgenual cortex in psychotic major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25292261. |
we hypothesized that resting-state functional connectivity between the hypothalamus and the subgenual cortex would be associated with altered circadian rhythm in patients with depression and depressive symptoms. |
2016-01-05 |
2023-08-13 |
human |
| Keith Sudheimer, Jennifer Keller, Rowena Gomez, Lakshika Tennakoon, Allan Reiss, Amy Garrett, Heather Kenna, Ruth O'Hara, Alan F Schatzber. Decreased hypothalamic functional connectivity with subgenual cortex in psychotic major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25292261. |
resting-state functional magnetic resonance imaging (fmri) scans were collected to observe low-frequency resting-state functional connectivity patterns of the hypothalamus in 39 healthy participants, 39 patients with major depression, and 22 patients with major depression with psychotic symptoms. |
2016-01-05 |
2023-08-13 |
human |
| Keith Sudheimer, Jennifer Keller, Rowena Gomez, Lakshika Tennakoon, Allan Reiss, Amy Garrett, Heather Kenna, Ruth O'Hara, Alan F Schatzber. Decreased hypothalamic functional connectivity with subgenual cortex in psychotic major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25292261. |
this study suggests that the communication between the hypothalamus and the subgenual cortex is disrupted in patients with major depression with psychotic features. |
2016-01-05 |
2023-08-13 |
human |
| Jing Lu, Xue-Yan Wu, Qiong-Bin Zhu, Jia Li, Li-Gen Shi, Juan-Li Wu, Qi-Jun Zhang, Man-Li Huang, Ai-Min Ba. Sex differences in the stress response in SD rats. Behavioural brain research. vol 284. 2015-12-07. PMID:25687843. |
stress affects the behavioral, endocrine and the molecular response of the stress systems in the hypothalamus of sd rats in a clear sexual dimorphic way, which has parallels in human data on stress and depression. |
2015-12-07 |
2023-08-13 |
human |
| Qirong Wan, Kai Gao, Han Rong, Min Wu, Huiling Wang, Xiaoping Wang, Gaohua Wang, Zhongchun Li. Histone modifications of the Crhr1 gene in a rat model of depression following chronic stress. Behavioural brain research. vol 271. 2015-08-06. PMID:24867333. |
these data are the first in vivo evidence of a role for chromatin modifications in the regulation of crhr1 gene expression in the hypothalamus, and may provide novel insight into therapeutic approaches to treat depression. |
2015-08-06 |
2023-08-13 |
rat |
| Allen L Ho, Eric S Sussman, Michael Zhang, Arjun V Pendharkar, Dan E Azagury, Cara Bohon, Casey H Halper. Deep Brain Stimulation for Obesity. Cureus. vol 7. issue 3. 2015-07-16. PMID:26180683. |
recent clinical trials of deep brain stimulation (dbs) in chronic cluster headache, alzheimer's disease, and depression and obsessive-compulsive disorder have demonstrated the safety and efficacy of targeting the hypothalamus and reward circuitry of the brain with electrical stimulation, and thus provide the basis for a neuromodulatory approach to treatment-refractory obesity. |
2015-07-16 |
2023-08-13 |
Not clear |