| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Glenna J Wallis, Laura A Bell, John N Wagner, Lauren Buxton, Lakshmini Balachandar, Karen S Wilco. Reactive microglia fail to respond to environmental damage signals in a viral-induced mouse model of temporal lobe epilepsy. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38558969. |
reactive microglia fail to respond to environmental damage signals in a viral-induced mouse model of temporal lobe epilepsy. |
2024-04-01 |
2024-04-04 |
mouse |
| Lauren Marijke Lankhuijzen, Thomas Ridle. Opioids, microglia, and temporal lobe epilepsy. Frontiers in neurology. vol 14. 2024-01-22. PMID:38249734. |
opioids, microglia, and temporal lobe epilepsy. |
2024-01-22 |
2024-01-24 |
Not clear |
| Jing-Jing Yang, Ying-Xin Liu, Yan-Fang Wang, Bi-Ying Ge, Ying Wang, Qing-Shan Wang, Sheng Li, Jian-Jie Zhang, Ling-Ling Jin, Jau-Shyong Hong, Sheng-Ming Yin, Jie Zha. Anti-epileptic and Neuroprotective Effects of Ultra-low Dose NADPH Oxidase Inhibitor Dextromethorphan on Kainic Acid-induced Chronic Temporal Lobe Epilepsy in Rats. Neuroscience bulletin. 2023-11-16. PMID:37973720. |
neuroinflammation mediated by microglia and oxidative stress play pivotal roles in the development of chronic temporal lobe epilepsy (tle). |
2023-11-16 |
2023-11-20 |
rat |
| Pingping Li, Xuefei Ji, Ming Shan, Yi Wang, Xingliang Dai, Mengyuan Yin, Yunlong Liu, Liao Guan, Lei Ye, Hongwei Chen. Melatonin regulates microglial polarization to M2 cell via RhoA/ROCK signaling pathway in epilepsy. Immunity, inflammation and disease. vol 11. issue 6. 2023-06-29. PMID:37382264. |
microglia (mg), a resident immunocyte localizing in central nervous system is reported to play important functions in the animal model of temporal lobe epilepsy (tle). |
2023-06-29 |
2023-08-14 |
Not clear |
| Jianchen Fan, Xinyan Dong, Yejiao Tang, Xuehui Wang, Donghui Lin, Lifen Gong, Chen Chen, Jie Jiang, Weida Shen, Anyu Xu, Xiangnan Zhang, Yicheng Xie, Xin Huang, Linghui Zen. Preferential pruning of inhibitory synapses by microglia contributes to alteration of the balance between excitatory and inhibitory synapses in the hippocampus in temporal lobe epilepsy. CNS neuroscience & therapeutics. 2023-04-19. PMID:37072932. |
preferential pruning of inhibitory synapses by microglia contributes to alteration of the balance between excitatory and inhibitory synapses in the hippocampus in temporal lobe epilepsy. |
2023-04-19 |
2023-08-14 |
Not clear |
| Amy M Smith, Thomas In-Hyeup Park, Miranda Aalderink, Robyn L Oldfield, Peter S Bergin, Edward W Mee, Richard L M Faull, Mike Draguno. Distinct characteristics of microglia from neurogenic and non-neurogenic regions of the human brain in patients with Mesial Temporal Lobe Epilepsy. Frontiers in cellular neuroscience. vol 16. 2022-11-25. PMID:36425665. |
distinct characteristics of microglia from neurogenic and non-neurogenic regions of the human brain in patients with mesial temporal lobe epilepsy. |
2022-11-25 |
2023-08-14 |
human |
| Lukas Henning, Henrike Antony, Annika Breuer, Julia Müller, Gerald Seifert, Etienne Audinat, Parmveer Singh, Frederic Brosseron, Michael T Heneka, Christian Steinhäuser, Peter Bedne. Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. Glia. 2022-11-14. PMID:36373840. |
reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. |
2022-11-14 |
2023-08-14 |
mouse |
| Lukas Henning, Henrike Antony, Annika Breuer, Julia Müller, Gerald Seifert, Etienne Audinat, Parmveer Singh, Frederic Brosseron, Michael T Heneka, Christian Steinhäuser, Peter Bedne. Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. Glia. 2022-11-14. PMID:36373840. |
extensive microglia reactivity has been well described in human and experimental temporal lobe epilepsy (tle). |
2022-11-14 |
2023-08-14 |
mouse |
| Shinichi Kinoshita, Ryuta Koyam. Pro- and anti-epileptic roles of microglia. Neural regeneration research. vol 16. issue 7. 2021-07-28. PMID:33318419. |
in mesial temporal lobe epilepsy, one of the most common form of epilepsies, microglia exhibit at least two distinct morphologies, amoeboid shape and ramified shape. |
2021-07-28 |
2023-08-13 |
Not clear |
| Xian-Lian Deng, Li Feng, Zi-Xin Wang, Yue-E Zhao, Qiong Zhan, Xiao-Mei Wu, Bo Xiao, Yi Sh. The Runx1/Notch1 Signaling Pathway Participates in M1/M2 Microglia Polarization in a Mouse Model of Temporal Lobe Epilepsy and in BV-2 Cells. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32632543. |
the runx1/notch1 signaling pathway participates in m1/m2 microglia polarization in a mouse model of temporal lobe epilepsy and in bv-2 cells. |
2021-06-08 |
2023-08-13 |
mouse |
| Xian-Lian Deng, Li Feng, Zi-Xin Wang, Yue-E Zhao, Qiong Zhan, Xiao-Mei Wu, Bo Xiao, Yi Sh. The Runx1/Notch1 Signaling Pathway Participates in M1/M2 Microglia Polarization in a Mouse Model of Temporal Lobe Epilepsy and in BV-2 Cells. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32632543. |
however, little is known about the effect of runx1 and the notch1 signaling pathway on the phenotypic shift of microglia during neuroinflammation, especially in temporal lobe epilepsy (tle). |
2021-06-08 |
2023-08-13 |
mouse |
| Tasuku Araki, Yuji Ikegaya, Ryuta Koyam. Microglia attenuate the kainic acid-induced death of hippocampal neurons in slice cultures. Neuropsychopharmacology reports. vol 40. issue 1. 2021-05-28. PMID:31794154. |
status epilepticus-induced hippocampal neuronal death, astrogliosis, and the activation of microglia are common pathological changes in mesial temporal lobe epilepsy (mtle) with resistance to antiepileptic drugs. |
2021-05-28 |
2023-08-13 |
Not clear |
| Jing Peng, Kan Wang, Weiwei Xiang, Yan Li, Yong Hao, Yangtai Gua. Rosiglitazone polarizes microglia and protects against pilocarpine-induced status epilepticus. CNS neuroscience & therapeutics. vol 25. issue 12. 2020-10-26. PMID:31729170. |
activated microglia have been found in the forebrains and hippocampi of temporal lobe epilepsy (tle) patients and status epileptic (se) animal models. |
2020-10-26 |
2023-08-13 |
Not clear |
| Giampaolo Milior, Mélanie Morin-Brureau, Farah Chali, Caroline Le Duigou, Etienne Savary, Gilles Huberfeld, Nathalie Rouach, Johan Pallud, Laurent Capelle, Vincent Navarro, Bertrand Mathon, Stéphane Clemenceau, Richard Mile. Distinct P2Y Receptors Mediate Extension and Retraction of Microglial Processes in Epileptic and Peritumoral Human Tissue. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 7. 2020-08-19. PMID:31896671. |
here we examine motility of microglia stained with a fluorescent lectin in tissue slices from female and male epileptic patients diagnosed with mesial temporal lobe epilepsy or cortical glioma (peritumoral cortex). |
2020-08-19 |
2023-08-13 |
human |
| Toshimitsu Hiragi, Yuji Ikegaya, Ryuta Koyam. Microglia after Seizures and in Epilepsy. Cells. vol 7. issue 4. 2019-11-20. PMID:29597334. |
in this review, we mainly focus on the animal models of temporal lobe epilepsy (tle) and discuss the proepileptic and antiepileptic roles of activated microglia in the epileptic brain. |
2019-11-20 |
2023-08-13 |
Not clear |
| Mélanie Morin-Brureau, Giampaolo Milior, Juliette Royer, Farah Chali, Caroline Le Duigou, Etienne Savary, Corinne Blugeon, Laurent Jourdren, David Akbar, Sophie Dupont, Vincent Navarro, Michel Baulac, Franck Bielle, Bertrand Mathon, Stéphane Clemenceau, Richard Mile. Microglial phenotypes in the human epileptic temporal lobe. Brain : a journal of neurology. vol 141. issue 12. 2019-07-15. PMID:30462183. |
here we use transcriptomics, anatomy, imaging of living cells and elisa measurements of cytokine release to examine microglia from patients with temporal lobe epilepsies. |
2019-07-15 |
2023-08-13 |
mouse |
| Chun-Lei Han, Ming Ge, Yun-Peng Liu, Xue-Min Zhao, Kai-Liang Wang, Ning Chen, Wen-Jia Meng, Wei Hu, Jian-Guo Zhang, Liang Li, Fan-Gang Men. LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy. Journal of neuroinflammation. vol 15. issue 1. 2019-04-08. PMID:29636074. |
astrocyte and microglia activation are well-known features of temporal lobe epilepsy that may contribute to epileptogenesis. |
2019-04-08 |
2023-08-13 |
rat |
| Dale B Bosco, Jiaying Zheng, Zhiyan Xu, Jiyun Peng, Ukpong B Eyo, Ke Tang, Cheng Yan, Jun Huang, Lijie Feng, Gongxiong Wu, Jason R Richardson, Hui Wang, Long-Jun W. RNAseq analysis of hippocampal microglia after kainic acid-induced seizures. Molecular brain. vol 11. issue 1. 2018-10-22. PMID:29925434. |
microglia have been shown to be of critical importance to the progression of temporal lobe epilepsy. |
2018-10-22 |
2023-08-13 |
Not clear |
| Jonathan Vinet, Ilia D Vainchtein, Carlotta Spano, Carmela Giordano, Domenico Bordini, Giulia Curia, Massimo Dominici, Hendrikus W G M Boddeke, Bart J L Eggen, Giuseppe Biagin. Microglia are less pro-inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus. Glia. vol 64. issue 8. 2018-01-04. PMID:27246930. |
activated microglia, astrogliosis, expression of pro-inflammatory cytokines, blood brain barrier (bbb) leakage and peripheral immune cell infiltration are features of mesial temporal lobe epilepsy. |
2018-01-04 |
2023-08-13 |
mouse |
| Tianyi Li, Xuan Zhai, Jinqiu Jiang, Xiaojie Song, Wei Han, Jiannan Ma, Lingling Xie, Li Cheng, Hengsheng Chen, Li Jian. Intraperitoneal injection of IL-4/IFN-γ modulates the proportions of microglial phenotypes and improves epilepsy outcomes in a pilocarpine model of acquired epilepsy. Brain research. vol 1657. 2017-07-31. PMID:27956120. |
recent studies have reported microglia that are activated in the central nervous system (cns) in patients with temporal lobe epilepsy and animal models of epilepsy. |
2017-07-31 |
2023-08-13 |
mouse |