| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos A Lafourcade, Fraser T Sparks, Angelique Bordey, Ursula Wyneken, Michael H Mohammad. Cannabinoid regulation of neurons in the dentate gyrus during epileptogenesis. Role of CB1R-associated proteins and downstream pathways. Epilepsia vol issue 2023 36869624 |
the hippocampal formation plays a central role in the development of temporal lobe epilepsy (tle), a disease characterized by recurrent, unprovoked epileptic discharges. |
2023-03-04 |
2023-03-06 |
Not clear |
| Paul S Buckmaster, Bianca Reyes, Tahsin Kahn, Megan Wyet. Ventral hippocampal formation is the primary epileptogenic zone in a rat model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience vol issue 2022 35995562 |
ventral hippocampal formation is the primary epileptogenic zone in a rat model of temporal lobe epilepsy. |
2022-08-22 |
2023-01-30 |
rat |
| Alexander Grote, Dieter Henrik Heiland, Julia Taube, Christoph Helmstaedter, Vidhya M Ravi, Paulina Will, Elke Hattingen, Jan R\\xc3\\xbcdiger Sch\\xc3\\xbcre, Juri Alexander Witt, Annika Reimers, Christian Elger, Johannes Schramm, Albert J Becker, Daniel Dele. 'Hippocampal innate inflammatory gliosis only' in pharmacoresistant temporal lobe epilepsy. Brain : a journal of neurology vol issue 2022 35978480 |
drug-resistant mesial temporal lobe epilepsy is a devastating disease with seizure onset in the hippocampal formation. |
2022-08-18 |
2023-01-30 |
Not clear |
| Joseane Righes Marafiga, Mayara Vendramin Pasquetti, Maria Elisa Calcagnott. In vitro Oscillation Patterns Throughout the Hippocampal Formation in a Rodent Model of Epilepsy. Neuroscience vol 479 issue 2021 34710537 |
however, the dynamics of underlying oscillations during the epileptogenesis throughout the hippocampal formation in the temporal lobe epilepsy is not clear. |
2021-12-07 |
2023-01-26 |
rat |
| Xiaoxuan Fu, Youhua Wang, Abdelkader Nasreddine Belkacem, Qirui Zhang, Chong Xie, Yingxin Cao, Hao Cheng, Shenghua Che. Integrating Optimized Multiscale Entropy Model with Machine Learning for the Localization of Epileptogenic Hemisphere in Temporal Lobe Epilepsy Using Resting-State fMRI. Journal of healthcare engineering vol 2021 issue 2021 34745491 |
the rfmri data of 20 mesial temporal lobe epilepsy patients with positive indicators (the indicators of epileptogenic hemisphere in clinic) in the hippocampal formation on either left or right hemisphere (equally divided into two groups) on the structural mri were collected and preprocessed. |
2021-11-24 |
2023-01-26 |
Not clear |
| Antje Kilias, Ute H\\xc3\\xa4ussler, Katharina Heining, Ulrich P Froriep, Carola A Haas, Ulrich Eger. Theta frequency decreases throughout the hippocampal formation in a focal epilepsy model. Hippocampus vol 28 issue 6 2019 29473981 |
mesial temporal lobe epilepsy is characterized by focal, recurrent spontaneous seizures, sclerosis and granule cell dispersion (gcd) in the hippocampal formation. |
2019-05-29 |
2023-01-26 |
mouse |
| Sora Ahn, Sang Beom Jun, Hyang Woon Lee, Seungjun Le. Computational modeling of epileptiform activities in medial temporal lobe epilepsy combined with in vitro experiments. Journal of computational neuroscience vol 41 issue 2 2018 27416961 |
the model targets a hippocampal formation that is known to be an important lesion in medial temporal lobe epilepsy. |
2018-05-07 |
2023-01-25 |
Not clear |
| Meinrad Drexel, Roman A Romanov, James Wood, Stefan Weger, Regine Heilbronn, Peer Wulff, Ramon O Tasan, Tibor Harkany, G\\xc3\\xbcnther Sper. Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 37 issue 34 2017 28733354 |
temporal lobe epilepsy (tle) is the most frequent form of focal epilepsies and is generally associated with malfunctioning of the hippocampal formation. |
2017-09-14 |
2023-01-26 |
mouse |
| Hai-Ying Shen, Erwin A van Vliet, Kerry-Ann Bright, Marissa Hanthorn, Nikki K Lytle, Jan Gorter, Eleonora Aronica, Detlev Boiso. Glycine transporter 1 is a target for the treatment of epilepsy. Neuropharmacology vol 99 issue 2016 26302655 |
using two different rodent models of temporal lobe epilepsy (tle)--the intrahippocampal kainic acid model of tle in mice, and the rat model of tetanic stimulation-induced tle--we first demonstrated robust overexpression of glyt1 in the hippocampal formation, suggesting dysfunctional glycine signaling in epilepsy. |
2016-08-30 |
2023-01-25 |
mouse |
| Rebecca Kulbida, Yipeng Wang, Eva-Maria Mandelkow, Susanne Schoch, Albert J Becker, Karen M J van Lo. Molecular imaging reveals epileptogenic Ca2+-channel promoter activation in hippocampi of living mice. Brain structure & function vol 220 issue 5 2016 24889163 |
focal epilepsies often originate in the hippocampal formation of the temporal lobe (temporal lobe epilepsy) and are generally acquired after transient brain insults. |
2016-08-19 |
2023-01-25 |
mouse |
| Roni Dhaher, Helen Wang, Shaun E Gruenbaum, Nathan Tu, Tih-Shih W Lee, Hitten P Zaveri, Tore Ei. Effects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy. Epilepsy research vol 115 issue 2016 26220375 |
gs is deficient in discrete regions of the hippocampal formation in patients with mesial temporal lobe epilepsy (mtle), a disorder characterized by brain glutamate excess and recurrent seizures. |
2016-04-25 |
2023-01-25 |
rat |
| Robert S Fishe. Stimulation of the medial septum should benefit patients with temporal lobe epilepsy. Medical hypotheses vol 84 issue 6 2016 25771138 |
this might be improved with septal stimulation, which has strong and direct reciprocal connections with the hippocampal formation, the structure most involved in temporal lobe epilepsy. |
2016-03-28 |
2023-01-25 |
rat |
| Rabia Soussi, Jean-Luc Boulland, Emilie Bassot, H\\xc3\\xa9l\\xc3\\xa8ne Bras, Patrice Coulon, Farrukh Abbas Chaudhry, Jon Storm-Mathisen, Lotfi Ferhat, Monique Esclape. Reorganization of supramammillary-hippocampal pathways in the rat pilocarpine model of temporal lobe epilepsy: evidence for axon terminal sprouting. Brain structure & function vol 220 issue 4 2016 24889162 |
in mesial temporal lobe epilepsy (mtle), spontaneous seizures likely originate from a multi-structural epileptogenic zone, including several regions of the limbic system connected to the hippocampal formation. |
2016-03-18 |
2023-01-25 |
rat |
| Ana Paula Andrade Hamad, Henrique Carrete, Marino Muxfeldt Bianchin, Taissa Ferrari-Marinho, Katia Lin, Elza M\\xc3\\xa1rcia Targas Yacubian, Luiz Celso Pereira Vilanova, Eliana Garzon, Lu\\xc3\\xads Ot\\xc3\\xa1vio Caboclo, Am\\xc3\\xa9rico Ceiki Sakamot. Morphological variations of hippocampal formation in epilepsy: image, clinical and electrophysiological data. Epilepsy & behavior : E&B vol 26 issue 1 2013 23220462 |
this study analyzes the hippocampal formation (hf) morphology of asymptomatic individuals (n = 30) and of patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis (mtle-hs) (n = 68), patients with malformations of cortical development (mcd) (n = 34), or patients with pure morphological variations of hippocampal formation (pure mvhf) (n = 12). |
2013-06-05 |
2023-01-25 |
Not clear |
| Tore Eid, Tih-Shih W Lee, Yue Wang, Edgar Perez, Edgar Per\\xc3\\xa9z, Jana Drummond, Fredrik Lauritzen, Linda H Bergersen, James H Meador-Woodruff, Dennis D Spencer, Nihal C de Lanerolle, Robert E McCullumsmit. Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy. Epilepsia vol 54 issue 2 2013 23384343 |
gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy. |
2013-04-02 |
2023-01-25 |
human |
| J Chwiej, J Kutorasinska, K Janeczko, K Gzielo-Jurek, L Uram, K Appel, R Simon, Z Setkowic. Progress of elemental anomalies of hippocampal formation in the pilocarpine model of temporal lobe epilepsy--an X-ray fluorescence microscopy study. Analytical and bioanalytical chemistry vol 404 issue 10 2013 23052869 |
progress of elemental anomalies of hippocampal formation in the pilocarpine model of temporal lobe epilepsy--an x-ray fluorescence microscopy study. |
2013-03-14 |
2023-01-25 |
rat |
| Pierangelo Cifelli, Anthony A Grac. Pilocarpine-induced temporal lobe epilepsy in the rat is associated with increased dopamine neuron activity. The international journal of neuropsychopharmacology vol 15 issue 7 2012 21745437 |
temporal lobe epilepsy (tle) is defined as the occurrence of spontaneous seizures that involve the limbic system, with the hippocampal formation and associated structures being central to the most prevalent refractory form of adult focal epilepsy. |
2012-12-11 |
2023-01-25 |
rat |
| Fredrik Lauritzen, Edgar L Perez, Eric R Melillo, Jung-Min Roh, Hitten P Zaveri, Tih-Shih W Lee, Yue Wang, Linda H Bergersen, Tore Ei. Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy. Neurobiology of disease vol 45 issue 1 2012 21856423 |
we recently reported that mct1 is deficient on microvessels in the epileptogenic hippocampal formation in patients with medication-refractory temporal lobe epilepsy (tle). |
2012-07-23 |
2023-01-25 |
human |
| Leena S Knight, H J\\xc3\\xbcrgen Wenzel, Philip A Schwartzkroi. Inhibition and interneuron distribution in the dentate gyrus of p35 knockout mice. Epilepsia vol 53 Suppl 1 issue 2012 22612821 |
the p35 knockout (p35-/-) mouse is an animal model of temporal lobe epilepsy that recapitulates key neuroanatomic abnormalities-granule cell dispersion and mossy fiber sprouting-observed in the hippocampal formation of humans, as well as spontaneous seizure activity. |
2012-07-16 |
2023-01-25 |
mouse |
| Ute H\\xc3\\xa4ussler, Lena Bielefeld, Ulrich P Froriep, Jakob Wolfart, Carola A Haa. Septotemporal position in the hippocampal formation determines epileptic and neurogenic activity in temporal lobe epilepsy. Cerebral cortex (New York, N.Y. : 1991) vol 22 issue 1 2012 21572089 |
septotemporal position in the hippocampal formation determines epileptic and neurogenic activity in temporal lobe epilepsy. |
2012-04-20 |
2023-01-25 |
Not clear |