| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ognen A C Petroff, Laura D Errante, Douglas L Rothman, Jung H Kim, Dennis D Spence. Neuronal and glial metabolite content of the epileptogenic human hippocampus. Annals of neurology vol 52 issue 5 2002 12402262 |
the hippocampal content of n-acetylaspartate, glutamate, gaba, glutamine, and aspartate is altered minimally by severe neuron loss in mesial temporal lobe epilepsy. |
2002-12-03 |
2023-01-24 |
human |
| Julie Lanthier, Alain Bouthillier, Marjolaine Lapointe, Michel Demeule, Richard B\\xc3\\xa9liveau, Richard R Desrosier. Down-regulation of protein L-isoaspartyl methyltransferase in human epileptic hippocampus contributes to generation of damaged tubulin. Journal of neurochemistry vol 83 issue 3 2002 12390520 |
these results demonstrate that the down-regulation of pimt in epileptic hippocampus leads to a significant accumulation of damaged tubulin that could contribute to neuron dysfunction in human mesial temporal lobe epilepsy. |
2002-11-26 |
2023-01-24 |
mouse |
| Hideji Uesugi, Hiroyuki Shimizu, Nobutaka Arai, Taketoshi Maehara, Toshio Mizutani, Kensuke Kawai, Hiroshi Nakayam. Pathological effect of seizures on the hippocampus in cases with temporal lobe epilepsy caused by brain tumors. Psychiatry and clinical neurosciences vol 56 issue 5 2002 12193247 |
pathological effect of seizures on the hippocampus in cases with temporal lobe epilepsy caused by brain tumors. |
2002-11-25 |
2023-01-24 |
Not clear |
| Hideji Uesugi, Hiroyuki Shimizu, Nobutaka Arai, Taketoshi Maehara, Toshio Mizutani, Kensuke Kawai, Hiroshi Nakayam. Pathological effect of seizures on the hippocampus in cases with temporal lobe epilepsy caused by brain tumors. Psychiatry and clinical neurosciences vol 56 issue 5 2002 12193247 |
in the present study, the pathological effect of epileptic seizures on the hippocampus was investigated in surgically treated patients with brain tumor-induced temporal lobe epilepsy. |
2002-11-25 |
2023-01-24 |
Not clear |
| Philip A Williams, Jean-Pierre Wuarin, Ping Dou, Damien J Ferraro, F Edward Dude. Reassessment of the effects of cycloheximide on mossy fiber sprouting and epileptogenesis in the pilocarpine model of temporal lobe epilepsy. Journal of neurophysiology vol 88 issue 4 2002 12364529 |
a feature of animal models of temporal lobe epilepsy and the human disorder is hippocampal sclerosis and timm stain in the inner molecular layer (iml) of the dentate gyrus, which represents synaptic reorganization and may be important in epileptogenesis. |
2002-11-25 |
2023-01-24 |
rat |
| Susanne G Mueller, Joyce Suhy, Kenneth D Laxer, Derek L Flenniken, Jana Axelrad, Andres A Capizzano, Michael W Weine. Reduced extrahippocampal NAA in mesial temporal lobe epilepsy. Epilepsia vol 43 issue 10 2002 12366737 |
structural and metabolic abnormalities in the hippocampal region in medial temporal lobe epilepsy (mtle) are well described; less is known about extrahippocampal changes. |
2002-11-25 |
2023-01-24 |
Not clear |
| Tomohiro Araki, Roger P Simon, Waro Taki, Jing-Quan Lan, David C Henshal. Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. Journal of neuroscience research vol 69 issue 5 2002 12210827 |
damage was largely restricted to the ipsilateral ca3 subfield of the hippocampus, but injury was also consistent within ca1, suggesting that this mouse model better reflects the hippocampal neuropathology of human temporal lobe epilepsy than does the rat, in which ca1 is typically spared. |
2002-11-15 |
2023-01-24 |
rat |
| S R Perosa, M A Porcionatto, A Cukiert, J R M Martins, C C Passeroti, D Amado, S L A Matas, H B Nader, E A Cavalheiro, J P Leite, M G Naffah-Mazzacoratt. Glycosaminoglycan levels and proteoglycan expression are altered in the hippocampus of patients with mesial temporal lobe epilepsy. Brain research bulletin vol 58 issue 5 2002 12242104 |
glycosaminoglycan levels and proteoglycan expression are altered in the hippocampus of patients with mesial temporal lobe epilepsy. |
2002-11-07 |
2023-01-24 |
Not clear |
| S R Perosa, M A Porcionatto, A Cukiert, J R M Martins, C C Passeroti, D Amado, S L A Matas, H B Nader, E A Cavalheiro, J P Leite, M G Naffah-Mazzacoratt. Glycosaminoglycan levels and proteoglycan expression are altered in the hippocampus of patients with mesial temporal lobe epilepsy. Brain research bulletin vol 58 issue 5 2002 12242104 |
hippocampal sclerosis is the most frequent pathologic finding in patients with intractable mesial temporal lobe epilepsy (mtle), which is associated with neuron loss, reactive gliosis, and mossy fiber sprouting. |
2002-11-07 |
2023-01-24 |
Not clear |
| Oliver von Bohlen und Halbach, Doris Albrech. Reciprocal connections of the hippocampal area CA1, the lateral nucleus of the amygdala and cortical areas in a combined horizontal slice preparation. Neuroscience research vol 44 issue 1 2002 12204297 |
the entorhinal and perirhinal cortices, the hippocampus and the amygdala are heavily interconnected limbic structures that are implicated in memory, and under pathological conditions, in seizure generation and propagation of temporal lobe epilepsy. |
2002-10-23 |
2023-01-24 |
Not clear |
| Renato L Marchetti, C\\xc3\\xa1ssio M C Bottino, Dion\\xc3\\xadsio Azevedo, Suely K Nagahashi Marie, Cl\\xc3\\xa1udio C de Castr. [Reliability of volumetric measures of mesial temporal structures]. Arquivos de neuro-psiquiatria vol 60 issue 2-B 2002 12131944 |
the development of reliable techniques for volumetric measurement of mesial temporal structures (amygdala, hippocampus and parahippocampal gyrus) on magnetic resonance imaging (mri) can provide data for the study of neuropsychiatric disorders, mainly temporal lobe epilepsy, alzheimer's disease and schizophrenia. |
2002-10-22 |
2023-01-24 |
Not clear |
| X R Zhang, D Han, Y F Tang, M L Liu, X Y Wan. [Studies on behavioral and electrographic seizures and structural abnormalities using magnetic resonance image in chronic epilepsy model in rats--hippocampal-entorhinal-tempral neocortex neural pathway]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology vol 16 issue 4 2002 11236675 |
repeated tetanus (60 hz, 0.4-0.6 ma, 2 s) were delivered into the right and the left dorsal hippocampus (hpc), or into the right and the left medial temporal neocortex (mtnc) respectively to establish chronic temporal lobe epilepsy model in rats. |
2002-10-16 |
2023-01-24 |
rat |
| P Vermathen, G Ende, K D Laxer, J A Walker, R C Knowlton, N M Barbaro, G B Matson, M W Weine. Temporal lobectomy for epilepsy: recovery of the contralateral hippocampus measured by (1)H MRS. Neurology vol 59 issue 4 2002 12196667 |
temporal lobectomy for epilepsy: recovery of the contralateral hippocampus measured by (1)h mrs. (1)h mrs imaging was obtained from 10 patients with mesial temporal lobe epilepsy before and after surgery. |
2002-09-20 |
2023-01-24 |
Not clear |
| Rod C Scott, D G Gadian, M D King, W K Chong, T C Cox, B G R Neville, A Connell. Magnetic resonance imaging findings within 5 days of status epilepticus in childhood. Brain : a journal of neurology vol 125 issue Pt 9 2002 12183341 |
the nature of the relationships between status epilepticus, acute hippocampal injury, mesial temporal sclerosis (mts) and temporal lobe epilepsy remains unclear. |
2002-09-17 |
2023-01-24 |
human |
| V Riban, V Bouilleret, B T Pham-L\\xc3\\xaa, J-M Fritschy, C Marescaux, A Depauli. Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy. Neuroscience vol 112 issue 1 2002 12044475 |
evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy. |
2002-09-06 |
2023-01-24 |
mouse |
| V Riban, V Bouilleret, B T Pham-L\\xc3\\xaa, J-M Fritschy, C Marescaux, A Depauli. Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy. Neuroscience vol 112 issue 1 2002 12044475 |
unilateral intrahippocampal injection of kainic acid in adult mice reproduces most of the morphological characteristics of hippocampal sclerosis (neuronal loss, gliosis, reorganization of neurotransmitter receptors, mossy fiber sprouting, granule cell dispersion) observed in patients with temporal lobe epilepsy. |
2002-09-06 |
2023-01-24 |
mouse |
| V Riban, V Bouilleret, B T Pham-L\\xc3\\xaa, J-M Fritschy, C Marescaux, A Depauli. Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy. Neuroscience vol 112 issue 1 2002 12044475 |
our data further validate intrahippocampal injection of kainate in mice as a model of temporal lobe epilepsy and suggest that synaptic reorganization in the lesioned hippocampus is necessary for the development of organized recurrent seizures. |
2002-09-06 |
2023-01-24 |
mouse |
| Ulrich Ebert, Claudia Brandt, Wolfgang L\\xc3\\xb6sche. Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat. Epilepsia vol 43 Suppl 5 issue 2002 12121301 |
hippocampal sclerosis and massive neurodegeneration in other parts of the limbic system are considered hallmarks of temporal lobe epilepsy. |
2002-09-06 |
2023-01-24 |
rat |
| Katarzyna Lukasiuk, Terhi J Pirttil\\xc3\\xa4, Asla Pitk\\xc3\\xa4ne. Upregulation of cystatin C expression in the rat hippocampus during epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy. Epilepsia vol 43 Suppl 5 issue 2002 12121309 |
upregulation of cystatin c expression in the rat hippocampus during epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy. |
2002-09-06 |
2023-01-24 |
rat |
| Sabine Furtinger, S Pirker, T Czech, C Baumgartner, G Sper. Altered expression of neuropeptide Y, -Y(1), and -Y(2) receptors in the hippocampus of patients with mesial temporal lobe epilepsy. Epilepsia vol 43 Suppl 5 issue 2002 12121311 |
altered expression of neuropeptide y, -y(1), and -y(2) receptors in the hippocampus of patients with mesial temporal lobe epilepsy. |
2002-09-06 |
2023-01-24 |
Not clear |