| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| S P Bower, C J Kilpatrick, S J Vogrin, K Morris, M J Coo. Degree of hippocampal atrophy is not related to a history of febrile seizures in patients with proved hippocampal sclerosis. Journal of neurology, neurosurgery, and psychiatry vol 69 issue 6 2000 11080224 |
to determine whether or not there is a relation between age of seizure onset, duration of temporal lobe epilepsy, or seizure frequency, and severity of hippocampal atrophy. |
2000-12-22 |
2023-01-24 |
Not clear |
| S Nishio, T Morioka, K Hisada, M Fuku. Temporal lobe epilepsy: a clinicopathological study with special reference to temporal neocortical changes. Neurosurgical review vol 23 issue 2 2000 10926100 |
in addition to hippocampal sclerosis, cerebral microdysgenesis and gliosis in the lateral structures of the temporal lobe may have a significant role in epileptogenesis of temporal lobe epilepsy. |
2000-12-07 |
2023-01-24 |
Not clear |
| C C Kanos, K G Davies, T O'Brien, F C Doha. Hippocampal sclerosis in a two-year-old with temporal lobe epilepsy: case report with pathological confirmation. Pediatric neurosurgery vol 32 issue 6 2000 10971193 |
hippocampal sclerosis in a two-year-old with temporal lobe epilepsy: case report with pathological confirmation. |
2000-11-21 |
2023-01-24 |
Not clear |
| S Beyenburg, M Watzka, I Bl\\xc3\\xbcmcke, J Schramm, F Bidlingmaier, C E Elger, B Stoffel-Wagne. Expression of mRNAs encoding for 17beta-hydroxisteroid dehydrogenase isozymes 1, 2, 3 and 4 in epileptic human hippocampus. Epilepsy research vol 41 issue 1 2000 10924871 |
therefore, we investigated the expression of 17beta-hsd 1, 2, 3 and 4 mrnas in hippocampal tissue specimens obtained at neurosurgery from 42 patients with pharmacoresistant temporal lobe epilepsy. |
2000-11-20 |
2023-01-24 |
human |
| V Bouilleret, F Loup, T Kiener, C Marescaux, J M Fritsch. Early loss of interneurons and delayed subunit-specific changes in GABA(A)-receptor expression in a mouse model of mesial temporal lobe epilepsy. Hippocampus vol 10 issue 3 2000 10902900 |
unilateral injection of kainic acid (ka) into the dorsal hippocampus of adult mice induces spontaneous recurrent partial seizures and replicates histopathological changes observed in human mesial temporal lobe epilepsy (mtle) (bouilleret v et al., neuroscience 1999; 89:717-729). |
2000-11-07 |
2023-01-24 |
mouse |
| M Maier, J Mellers, B Toone, M Trimble, M A Ro. Schizophrenia, temporal lobe epilepsy and psychosis: an in vivo magnetic resonance spectroscopy and imaging study of the hippocampus/amygdala complex. Psychological medicine vol 30 issue 3 2000 10883713 |
we have used proton magnetic resonance imaging and spectroscopy to measure hippocampus/amygdala volumes and anterior hippocampal metabolite concentrations (n-acetyl aspartate (naa), creatine/phosphocreatine and choline) in subjects with temporal lobe epilepsy (tle), schizophrenia and in normal controls. |
2000-11-01 |
2023-01-24 |
human |
| A K Shetty, V Zaman, D A Turne. Pattern of long-distance projections from fetal hippocampal field CA3 and CA1 cell grafts in lesioned CA3 of adult hippocampus follows intrinsic character of respective donor cells. Neuroscience vol 99 issue 2 2000 10938430 |
further, the robust and specific projections observed from ca3 grafts is likely beneficial for functional recovery of hippocampus following ca3 injury and hence of significance towards developing a graft-mediated therapy for human temporal lobe epilepsy. |
2000-10-19 |
2023-01-24 |
human |
| V Andr\\xc3\\xa9, A Ferrandon, C Marescaux, A Nehli. Electroshocks delay seizures and subsequent epileptogenesis but do not prevent neuronal damage in the lithium-pilocarpine model of epilepsy. Epilepsy research vol 42 issue 1 2000 10996502 |
as temporal lobe epilepsy is linked to neuronal damage in the hippocampus, we tested the effect of repeated ecs on subsequent status epilepticus (se) induced by lithium-pilocarpine and leading to cell death and temporal epilepsy in the rat. |
2000-10-19 |
2023-01-24 |
rat |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 20 issue 18 2000 10995855 |
because both verbal memory processes and synaptic plasticity are impaired by a hippocampal seizure focus, we suggest that impaired synaptic plasticity may contribute to deficient declarative memory in human temporal lobe epilepsy. |
2000-10-18 |
2023-01-24 |
human |
| D A Coulte. Mossy fiber zinc and temporal lobe epilepsy: pathological association with altered \"epileptic\" gamma-aminobutyric acid A receptors in dentate granule cells. Epilepsia vol 41 Suppl 6 issue 2000 10999528 |
temporal lobe epilepsy is associated with circuit rearrangements within the hippocampus. |
2000-10-17 |
2023-01-24 |
Not clear |
| I Bl\\xc3\\xbcmcke, B Suter, K Behle, R Kuhn, J Schramm, C E Elger, O D Wiestle. Loss of hilar mossy cells in Ammon's horn sclerosis. Epilepsia vol 41 Suppl 6 issue 2000 10999540 |
here we have subjected hilar mossy cell loss in the hippocampus of patients with chronic temporal lobe epilepsy (tle) to a systematic morphological and immunohistochemical analysis. |
2000-10-17 |
2023-01-24 |
Not clear |
| W Schr\\xc3\\xb6der, S Hinterkeuser, G Seifert, J Schramm, R Jabs, G P Wilkin, C Steinh\\xc3\\xa4use. Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy. Epilepsia vol 41 Suppl 6 issue 2000 10999541 |
in this study, functional properties of astrocytes were investigated in acute hippocampal brain slices obtained from surgical specimens of patients with drug-resistant temporal lobe epilepsy (tle). |
2000-10-17 |
2023-01-24 |
human |
| R E Hogan, R D Bucholz, I Choudhuri, K E Mark, C S Butler, S Josh. Shape analysis of hippocampal surface structure in patients with unilateral mesial temporal sclerosis. Journal of digital imaging vol 13 issue 2 Suppl 1 2000 10847359 |
we applied a previously validated technique of deformation-based hippocampal segmentations in 20 subjects with documented unilateral mesial temporal sclerosis (mts) and temporal lobe epilepsy. |
2000-10-12 |
2023-01-24 |
human |
| R E Hogan, K E Mark, I Choudhuri, L Wang, S Joshi, M I Miller, R D Buchol. Magnetic resonance imaging deformation-based segmentation of the hippocampus in patients with mesial temporal sclerosis and temporal lobe epilepsy. Journal of digital imaging vol 13 issue 2 Suppl 1 2000 10847408 |
magnetic resonance imaging deformation-based segmentation of the hippocampus in patients with mesial temporal sclerosis and temporal lobe epilepsy. |
2000-10-12 |
2023-01-24 |
Not clear |
| A E Telfeian, H J Federoff, P Leone, M J During, A Williamso. Overexpression of GluR6 in rat hippocampus produces seizures and spontaneous nonsynaptic bursting in vitro. Neurobiology of disease vol 7 issue 4 2000 10964607 |
we hypothesized that overexpression of specific glutamate receptors within the hippocampus would induce seizures and the associated cellular changes seen in temporal lobe epilepsy (tle). |
2000-10-11 |
2023-01-24 |
rat |
| B Szelies, G Weber-Luxenburger, R Mielke, G Pawlik, J Kessler, U Pietrzyk, B Bauer, W D Heis. Interictal hippocampal benzodiazepine receptors in temporal lobe epilepsy: comparison with coregistered hippocampal metabolism and volumetry. European journal of neurology vol 7 issue 4 2000 10971598 |
interictal hippocampal benzodiazepine receptors in temporal lobe epilepsy: comparison with coregistered hippocampal metabolism and volumetry. |
2000-09-28 |
2023-01-24 |
Not clear |
| B Szelies, G Weber-Luxenburger, R Mielke, G Pawlik, J Kessler, U Pietrzyk, B Bauer, W D Heis. Interictal hippocampal benzodiazepine receptors in temporal lobe epilepsy: comparison with coregistered hippocampal metabolism and volumetry. European journal of neurology vol 7 issue 4 2000 10971598 |
the significance of benzodiazepine receptor (bzr) concentration in comparison with hippocampal metabolism and volumetry was assessed in 14 patients diagnosed with temporal lobe epilepsy (tle) without hippocampal signal change on t2-weighted magnetic resonance imaging (mri) scans. |
2000-09-28 |
2023-01-24 |
Not clear |
| M V Spanaki, L Kopylev, K Liow, C DeCarli, S Fazilat, W D Gaillard, W H Theodor. Relationship of seizure frequency to hippocampus volume and metabolism in temporal lobe epilepsy. Epilepsia vol 41 issue 9 2000 10999564 |
relationship of seizure frequency to hippocampus volume and metabolism in temporal lobe epilepsy. |
2000-09-26 |
2023-01-24 |
Not clear |
| M Watzka, S Beyenburg, I Bl\\xc3\\xbcmcke, C E Elger, F Bidlingmaier, B Stoffel-Wagne. Expression of mineralocorticoid and glucocorticoid receptor mRNA in the human hippocampus. Neuroscience letters vol 290 issue 2 2000 10936692 |
we used competitive reverse transcription-polymerase chain reaction to quantify the amount of mr and gr mrna in hippocampal tissue obtained from patients with temporal lobe epilepsy. |
2000-09-21 |
2023-01-24 |
human |
| S Dupont, P F Van de Moortele, S Samson, D Hasboun, J B Poline, C Adam, S Leh\\xc3\\xa9ricy, D Le Bihan, Y Samson, M Baula. Episodic memory in left temporal lobe epilepsy: a functional MRI study. Brain : a journal of neurology vol 123 ( Pt 8) issue 2000 10908201 |
left medial temporal lobe epilepsy (mtle) is associated with verbal memory impairment usually related to hippocampal damage. |
2000-09-08 |
2023-01-24 |
human |