| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Carolina Coan, Eliane Kobayashi, Li Min Li, Fernando Cende. Quantification of hippocampal signal intensity in patients with mesial temporal lobe epilepsy. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 13. issue 3. 2003-09-25. PMID:12889169. |
refractory mesial temporal lobe epilepsy (mtle) is frequently associated with hippocampal atrophy (ha) and an abnormal hippocampal signal (hsig) on magnetic resonance imaging (mri). |
2003-09-25 |
2023-08-12 |
Not clear |
| Tengis Gloveli, Joachim Behr, Tamar Dugladze, Zaal Kokaia, Merab Kokaia, Uwe Heineman. Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABA(B) autoreceptors in layer III of the entorhinal cortex. Neurobiology of disease. vol 13. issue 3. 2003-09-25. PMID:12901834. |
we studied the effect of kindling, a model of temporal lobe epilepsy, on the frequency-dependent information transfer from the entorhinal cortex to the hippocampus in vitro. |
2003-09-25 |
2023-08-12 |
rat |
| Susanne G Mueller, Kenneth D Laxer, Joyce Suhy, Ria C Lopez, Derek L Flenniken, Michael W Weine. Spectroscopic metabolic abnormalities in mTLE with and without MRI evidence for mesial temporal sclerosis using hippocampal short-TE MRSI. Epilepsia. vol 44. issue 7. 2003-09-24. PMID:12823584. |
long echo time (te) spectroscopy reliably identifies the epileptogenic hippocampus in mesial temporal lobe epilepsy. |
2003-09-24 |
2023-08-12 |
Not clear |
| Stefan Vielhaber, Joachim H Von Oertzen, Alexei F Kudin, Ariel Schoenfeld, Christian Menzel, Hans-Juergen Biersack, Thomas Kral, Christian E Elger, Wolfram S Kun. Correlation of hippocampal glucose oxidation capacity and interictal FDG-PET in temporal lobe epilepsy. Epilepsia. vol 44. issue 2. 2003-09-09. PMID:12558573. |
correlation of hippocampal glucose oxidation capacity and interictal fdg-pet in temporal lobe epilepsy. |
2003-09-09 |
2023-08-12 |
Not clear |
| Beate Diehl, Eric LaPresto, Imad Najm, Shanker Raja, Sabine Rona, Thomas Babb, Zhong Ying, William Bingaman, Hans O Lüders, Paul Ruggier. Neocortical temporal FDG-PET hypometabolism correlates with temporal lobe atrophy in hippocampal sclerosis associated with microscopic cortical dysplasia. Epilepsia. vol 44. issue 4. 2003-09-09. PMID:12681005. |
medically intractable temporal lobe epilepsy (tle) due to hippocampal sclerosis (hs), with or without cortical dysplasia (cd), is associated with atrophy of the hippocampal formation and regional fluorodeoxyglucose positron-emission tomography (fdg-pet) hypometabolism. |
2003-09-09 |
2023-08-12 |
Not clear |
| Jan A Gorter, Pedro M Gonçalves Pereira, Erwin A van Vliet, Eleonora Aronica, Fernando H Lopes da Silva, Paul J Lucasse. Neuronal cell death in a rat model for mesial temporal lobe epilepsy is induced by the initial status epilepticus and not by later repeated spontaneous seizures. Epilepsia. vol 44. issue 5. 2003-09-09. PMID:12752463. |
to determine whether repeated seizures contribute to hippocampal sclerosis, we investigated whether cell loss in the (para) hippocampal region was related to the severity of chronic seizure activity in a rat model for temporal lobe epilepsy (tle). |
2003-09-09 |
2023-08-12 |
rat |
| Nihal C de Lanerolle, Jung H Kim, Anne Williamson, Susan S Spencer, Hitten P Zaveri, Tore Eid, Dennis D Spencer, Toye Ei. A retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: evidence for distinctive patient subcategories. Epilepsia. vol 44. issue 5. 2003-09-09. PMID:12752467. |
a retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: evidence for distinctive patient subcategories. |
2003-09-09 |
2023-08-12 |
human |
| Nihal C de Lanerolle, Jung H Kim, Anne Williamson, Susan S Spencer, Hitten P Zaveri, Tore Eid, Dennis D Spencer, Toye Ei. A retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: evidence for distinctive patient subcategories. Epilepsia. vol 44. issue 5. 2003-09-09. PMID:12752467. |
this study is a retrospective analysis of the pathology of the hippocampus from patients with medically intractable temporal lobe epilepsy. |
2003-09-09 |
2023-08-12 |
human |
| Else A Tolner, Erwin A van Vliet, Anthony J G D Holtmaat, Eleonora Aronica, Menno P Witter, Fernando H Lopes da Silva, Jan A Gorte. GAP-43 mRNA and protein expression in the hippocampal and parahippocampal region during the course of epileptogenesis in rats. The European journal of neuroscience. vol 17. issue 11. 2003-09-04. PMID:12814368. |
in order to reveal axonal rewiring in the hippocampal and parahippocampal regions after status epilepticus, we investigated the temporal evolution of growth-associated protein-43 (gap-43) mrna and protein expression in two rat models of mesial temporal lobe epilepsy (mtle). |
2003-09-04 |
2023-08-12 |
rat |
| Sirpa Rainesalo, Tapani Keränen, Jukka Peltola, Pirjo Saransaar. Glutamate uptake in blood platelets from epileptic patients. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742083. |
we studied glutamate uptake into blood platelets from patients with distinct epileptic syndromes: included were 20 patients with temporal lobe epilepsy and hippocampal sclerosis (tle+hs), 20 with juvenile myoclonus epilepsy (jme) and 20 healthy volunteers matched for age and sex. |
2003-08-19 |
2023-08-12 |
human |
| Luciano Neder, Valeria Valente, Carlos G Carlotti, João P Leite, João A Assirati, Maria L Paçó-Larson, Jorge E Moreir. Glutamate NMDA receptor subunit R1 and GAD mRNA expression in human temporal lobe epilepsy. Cellular and molecular neurobiology. vol 22. issue 5-6. 2003-08-13. PMID:12585688. |
molecular mechanisms underlying increased hippocampal excitability in human temporal lobe epilepsy (tle) are largely unknown. |
2003-08-13 |
2023-08-12 |
human |
| C Brandt, H Potschka, W Löscher, U Eber. N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in the kainate model of temporal lobe epilepsy. Neuroscience. vol 118. issue 3. 2003-08-08. PMID:12710980. |
most patients with temporal lobe epilepsy (tle), the most common type of epilepsy, show pronounced loss of neurons in limbic brain regions, including the hippocampus. |
2003-08-08 |
2023-08-12 |
rat |
| Karin Borges, Marla Gearing, Dayna L McDermott, Amy B Smith, Antoine G Almonte, Bruce H Wainer, Raymond Dingledin. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Experimental neurology. vol 182. issue 1. 2003-08-06. PMID:12821374. |
the rodent pilocarpine model of epilepsy exhibits hippocampal sclerosis and spontaneous seizures and thus resembles human temporal lobe epilepsy. |
2003-08-06 |
2023-08-12 |
mouse |
| Anthony J G D Holtmaat, Jan A Gorter, Joris De Wit, Else A Tolner, Sabine Spijker, Roman J Giger, Fernando H Lopes da Silva, Joost Verhaage. Transient downregulation of Sema3A mRNA in a rat model for temporal lobe epilepsy. A novel molecular event potentially contributing to mossy fiber sprouting. Experimental neurology. vol 182. issue 1. 2003-08-06. PMID:12821384. |
mossy fiber sprouting (mfs) in the hippocampal dentate gyrus is thought to play a critical role in the hyperexcitability of the hippocampus in temporal lobe epilepsy patients. |
2003-08-06 |
2023-08-12 |
rat |
| Zakaria Nanobashvili, Tamar Chachua, Avtandil Nanobashvili, Irina Bilanishvili, Olle Lindvall, Zaal Kokai. Suppression of limbic motor seizures by electrical stimulation in thalamic reticular nucleus. Experimental neurology. vol 181. issue 2. 2003-08-05. PMID:12781995. |
our data provide the first evidence that trn stimulations can act to suppress limbic motor seizures in hippocampal kindling and suggest a new approach for seizure control in temporal lobe epilepsy. |
2003-08-05 |
2023-08-12 |
rat |
| P M Thomas, J P Phillips, N Delanty, W T O'Conno. Elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus. Epilepsy research. vol 54. issue 1. 2003-07-21. PMID:12742599. |
we report preliminary results from four patients subjected to hippocampal electrocorticography and microdialysis during temporal lobe epilepsy surgery. |
2003-07-21 |
2023-08-12 |
human |
| L J Shanley, D O'Malley, A J Irving, M L Ashford, J Harve. Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels. The Journal of physiology. vol 545. issue 3. 2003-07-02. PMID:12482897. |
as uncontrolled excitability in the hippocampus is one underlying cause of temporal lobe epilepsy, this novel action of leptin could provide an alternative therapeutic target in the management of epilepsy. |
2003-07-02 |
2023-08-12 |
rat |
| Ana P Silva, Paulo S Pinheiro, Arsélio P Carvalho, Caetana M Carvalho, Birthe Jakobsen, Jens Zimmer, João O Malv. Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 9. 2003-06-25. PMID:12692082. |
glutamate and npy have been implicated in hippocampal neuropathology in temporal lobe epilepsy. |
2003-06-25 |
2023-08-12 |
rat |
| Theodor Petrov, José A Rafols, Sarah S Alousi, William J Kupsky, Robert Johnson, Jagdish Shah, Aashit Shah, Craig Watso. Cellular compartmentalization of phosphorylated eIF2alpha and neuronal NOS in human temporal lobe epilepsy with hippocampal sclerosis. Journal of the neurological sciences. vol 209. issue 1-2. 2003-06-16. PMID:12686399. |
cellular compartmentalization of phosphorylated eif2alpha and neuronal nos in human temporal lobe epilepsy with hippocampal sclerosis. |
2003-06-16 |
2023-08-12 |
human |
| Theodor Petrov, José A Rafols, Sarah S Alousi, William J Kupsky, Robert Johnson, Jagdish Shah, Aashit Shah, Craig Watso. Cellular compartmentalization of phosphorylated eIF2alpha and neuronal NOS in human temporal lobe epilepsy with hippocampal sclerosis. Journal of the neurological sciences. vol 209. issue 1-2. 2003-06-16. PMID:12686399. |
hippocampal sclerosis (hs) is the most common neuropathologic finding in patients with medically refractory temporal lobe epilepsy (tle). |
2003-06-16 |
2023-08-12 |
human |