| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susanne Tulke, Carola A Haas, Ute H\\xc3\\xa4ussle. Expression of brain-derived neurotrophic factor and structural plasticity in the dentate gyrus and CA2 region correlate with epileptiform activity. Epilepsia vol 60 issue 6 2020 31121074 |
hippocampal sclerosis is a hallmark of mesial temporal lobe epilepsy (mtle), comprising gliosis and neuronal loss in the hippocampus. |
2020-04-10 |
2023-01-26 |
Not clear |
| William A Schraegle, Nancy L Nussbaum, Jeffrey B Titu. Executive Dysfunction and Depression in Pediatric Temporal Lobe Epilepsy: The Contribution of Hippocampal Sclerosis and Psychosocial Factors. Journal of the International Neuropsychological Society : JINS vol 24 issue 6 2020 29573759 |
executive dysfunction and depression in pediatric temporal lobe epilepsy: the contribution of hippocampal sclerosis and psychosocial factors. |
2020-04-09 |
2023-01-26 |
Not clear |
| Siti Nurbaya Yaakub, Gareth J Barker, Sarah J Carr, Eugenio Abela, Michalis Koutroumanidis, Robert D C Elwes, Mark P Richardso. Abnormal temporal lobe morphology in asymptomatic relatives of patients with hippocampal sclerosis: A replication study. Epilepsia vol 60 issue 1 2020 30324623 |
we investigated gray and white matter morphology in patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle+hs) and first-degree asymptomatic relatives of patients with mtle+hs. |
2020-04-09 |
2023-01-26 |
human |
| Xin Tong, Dongmei An, Fenglai Xiao, Du Lei, Running Niu, Wei Li, Jiechuan Ren, Wenyu Liu, Yingying Tang, Le Zhang, Baiwan Zhou, Qiyong Gong, Dong Zho. Real-time effects of interictal spikes on hippocampus and amygdala functional connectivity in unilateral temporal lobe epilepsy: An EEG-fMRI study. Epilepsia vol 60 issue 2 2020 30653664 |
real-time effects of interictal spikes on hippocampus and amygdala functional connectivity in unilateral temporal lobe epilepsy: an eeg-fmri study. |
2020-04-08 |
2023-01-26 |
Not clear |
| Xin Tong, Dongmei An, Fenglai Xiao, Du Lei, Running Niu, Wei Li, Jiechuan Ren, Wenyu Liu, Yingying Tang, Le Zhang, Baiwan Zhou, Qiyong Gong, Dong Zho. Real-time effects of interictal spikes on hippocampus and amygdala functional connectivity in unilateral temporal lobe epilepsy: An EEG-fMRI study. Epilepsia vol 60 issue 2 2020 30653664 |
to explore the real-time effects of interictal epileptiform discharges (ieds) on hippocampus and amygdala functional connectivity (fc) in unilateral temporal lobe epilepsy (tle). |
2020-04-08 |
2023-01-26 |
Not clear |
| William D Hendricks, Gary L Westbrook, Eric Schnel. Early detonation by sprouted mossy fibers enables aberrant dentate network activity. Proceedings of the National Academy of Sciences of the United States of America vol 116 issue 22 2020 31085654 |
in temporal lobe epilepsy, sprouting of hippocampal mossy fiber axons onto dentate granule cell dendrites creates a recurrent excitatory network. |
2020-04-06 |
2023-01-26 |
Not clear |
| Fernando Cende. Evidence for a genetic effect in altered cortical surface area but not in cortical thinning in siblings of patients with mesial temporal lobe epilepsy: Commentary on: \"Abnormal temporal lobe morphology in asymptomatic relatives of patients with hippocampal sclerosis: A replication study\". Epilepsia vol 60 issue 1 2020 30592033 |
evidence for a genetic effect in altered cortical surface area but not in cortical thinning in siblings of patients with mesial temporal lobe epilepsy: commentary on: "abnormal temporal lobe morphology in asymptomatic relatives of patients with hippocampal sclerosis: a replication study". |
2020-04-02 |
2023-01-26 |
Not clear |
| Benoit Girard, Pola Tuduri, Maria Paula Moreno, Sophie Sakkaki, Cedric Barboux, Tristan Bouschet, Annie Varrault, Jihane Vitre, Isabelle McCort-Tranchepain, Julien Dairou, Francine Acher, Laurent Fagni, Nicola Marchi, Julie Perroy, Federica Bertas. The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures. Neurobiology of disease vol 129 issue 2020 31051234 |
in the intra-hippocampal injection of kainic acid mouse model that mimics the human mesial temporal lobe epilepsy, we found that lsp2-9166 reduces seizure frequency and hippocampal sclerosis. |
2020-03-24 |
2023-01-26 |
human |
| Pavel \\xc5\\x98ehulka, Jan Cimb\\xc3\\xa1ln\\xc3\\xadk, Martin Pail, Jan Chrastina, Mark\\xc3\\xa9ta Hermanov\\xc3\\xa1, Milan Br\\xc3\\xa1zdi. Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology vol 130 issue 7 2020 31100580 |
hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. |
2020-03-18 |
2023-01-26 |
Not clear |
| Priscila S R Sim\\xc3\\xb5es, Alexia O Zanelatto, Mirian C Assis, Pedro Paulo V Varella, Elza Marcia Yacubian, Henrique Carrete, Ricardo Centeno, Mariana S Araujo, Esper A Cavalheiro, Ivarne Luis S Tersariol, Guacyara Motta, Maria da Gra\\xc3\\xa7a Naffah-Mazzacoratt. Plasma kallikrein-kinin system contributes to peripheral inflammation in temporal lobe epilepsy. Journal of neurochemistry vol 150 issue 3 2020 31206169 |
temporal lobe epilepsy (tle) is a chronic disease, characterized by severe and refractory seizures, triggered in the hippocampus and/or amygdala, disrupting the blood-brain barrier. |
2020-03-18 |
2023-01-26 |
human |
| Ho-Joon Lee, Kang Min Par. Intrinsic hippocampal and thalamic networks in temporal lobe epilepsy with hippocampal sclerosis according to drug response. Seizure vol 76 issue 2020 31986443 |
intrinsic hippocampal and thalamic networks in temporal lobe epilepsy with hippocampal sclerosis according to drug response. |
2020-03-17 |
2023-01-26 |
Not clear |
| Ho-Joon Lee, Kang Min Par. Intrinsic hippocampal and thalamic networks in temporal lobe epilepsy with hippocampal sclerosis according to drug response. Seizure vol 76 issue 2020 31986443 |
the aim of this study was to investigate whether intrinsic hippocampal or thalamic networks in patients with temporal lobe epilepsy (tle) with hippocampal sclerosis (hs) were different according to antiepileptic drug (aed) response. |
2020-03-17 |
2023-01-26 |
Not clear |
| Jacint Sala-Padro, J\\xc3\\xbalia Mir\\xc3\\xb3, Antoni Rodriguez-Fornells, Manuel Quintana, Noem\\xc3\\xad Vidal, Gerard Plans, Mila Santurino, Merc\\xc3\\xa8 Falip, Estela Camar. Hippocampal microstructural architecture and surgical outcome: Hippocampal diffusivity could predict seizure relapse. Seizure vol 76 issue 2020 32044692 |
our aim was to study the microstructural architecture of the contralateral hippocampus to the affected side in patients with temporal lobe epilepsy with hippocampal sclerosis (tle-hs) and its relation with surgical outcome. |
2020-03-17 |
2023-01-26 |
Not clear |
| James Allebone, Richard Kanaan, Jerome Maller, Terry O'Brien, Saul Alator Mullen, Mark Cook, Sophia J Adams, Simon Vogrin, David N Vaughan, Alan Connelly, Patrick Kwan, S F Berkovic, Wendyl J D'Souza, Graeme Jackson, Dennis Velakoulis, Sarah J Wilso. Bilateral volume reduction in posterior hippocampus in psychosis of epilepsy. Journal of neurology, neurosurgery, and psychiatry vol 90 issue 6 2020 30796132 |
psychosis of epilepsy (poe) occurs more frequently in temporal lobe epilepsy, raising the question as to whether abnormalities of the hippocampus are aetiologically important. |
2020-03-13 |
2023-01-26 |
Not clear |
| Sebastian Guelfi, Juan A Botia, Maria Thom, Adaikalavan Ramasamy, Marina Perona, Lee Stanyer, Lillian Martinian, Daniah Trabzuni, Colin Smith, Robert Walker, Mina Ryten, Mark Reimers, Michael E Weale, John Hardy, Mar Matari. Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy. Brain : a journal of neurology vol 142 issue 6 2020 30932156 |
mesial temporal lobe epilepsy with hippocampal sclerosis represents the most common epilepsy syndrome in adult patients with medically intractable partial epilepsy. |
2020-03-12 |
2023-01-26 |
Not clear |
| Sebastian Guelfi, Juan A Botia, Maria Thom, Adaikalavan Ramasamy, Marina Perona, Lee Stanyer, Lillian Martinian, Daniah Trabzuni, Colin Smith, Robert Walker, Mina Ryten, Mark Reimers, Michael E Weale, John Hardy, Mar Matari. Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy. Brain : a journal of neurology vol 142 issue 6 2020 30932156 |
we performed a whole (gene and exon-level) transcriptome analysis on cortical tissue samples (brodmann areas 20 and 21) from 86 patients with mesial temporal lobe epilepsy with hippocampal sclerosis and 75 neurologically healthy controls. |
2020-03-12 |
2023-01-26 |
Not clear |
| Sebastian Guelfi, Juan A Botia, Maria Thom, Adaikalavan Ramasamy, Marina Perona, Lee Stanyer, Lillian Martinian, Daniah Trabzuni, Colin Smith, Robert Walker, Mina Ryten, Mark Reimers, Michael E Weale, John Hardy, Mar Matari. Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy. Brain : a journal of neurology vol 142 issue 6 2020 30932156 |
we report potential epilepsy-risk eqtls, some of which are specific to tissue from patients with mesial temporal lobe epilepsy with hippocampal sclerosis. |
2020-03-12 |
2023-01-26 |
Not clear |
| Sebastian Guelfi, Juan A Botia, Maria Thom, Adaikalavan Ramasamy, Marina Perona, Lee Stanyer, Lillian Martinian, Daniah Trabzuni, Colin Smith, Robert Walker, Mina Ryten, Mark Reimers, Michael E Weale, John Hardy, Mar Matari. Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy. Brain : a journal of neurology vol 142 issue 6 2020 30932156 |
we also found large transcriptional and splicing deregulation in mesial temporal lobe epilepsy with hippocampal sclerosis tissue as well as gene networks involving neuronal and glial mechanisms that provide new insights into the cause and maintenance of the seizures. |
2020-03-12 |
2023-01-26 |
Not clear |
| Kunal Gupta, Eric Schnel. Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy. PloS one vol 14 issue 10 2020 31596871 |
mouse models of mesial temporal lobe epilepsy recapitulate aspects of human epilepsy, which is characterized by neuronal network remodeling in the hippocampal dentate gyrus. |
2020-03-10 |
2023-01-26 |
mouse |
| Kunal Gupta, Eric Schnel. Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy. PloS one vol 14 issue 10 2020 31596871 |
we used the well-characterized mouse intrahippocampal kainate model of temporal lobe epilepsy to examine associations between hippocampal neurogenesis and altered wnt signaling after seizure induction. |
2020-03-10 |
2023-01-26 |
mouse |