| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Muhammad N Arshad, Simon Oppenheimer, Jaye Jeong, Bilge Buyukdemirtas, Janice R Naegel. Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy. Neurobiology of disease vol issue 2022 36183946 |
hippocampal transplants of fetal gabaergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy. |
2022-10-02 |
2023-01-30 |
mouse |
| Alfredo Lucas, Ravi Prakash Reddy Nanga, Peter Hadar, Stephanie Chen, Adam Gibson, Kelly Oechsel, Mark A Elliott, Joel M Stein, Sandhitsu Das, Ravinder Reddy, John A Detre, Kathryn A Davi. Mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted CEST (GluCEST) imaging. Human brain mapping vol issue 2022 36173151 |
mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted cest (glucest) imaging. |
2022-09-29 |
2023-01-30 |
Not clear |
| Sung Chul Lim, Juhee Oh, Bo Young Hong, Seong Hoon Li. Changes in the Brain in Temporal Lobe Epilepsy with Unilateral Hippocampal Sclerosis: An Initial Case Series. Healthcare (Basel, Switzerland) vol 10 issue 9 2022 36141260 |
changes in the brain in temporal lobe epilepsy with unilateral hippocampal sclerosis: an initial case series. |
2022-09-23 |
2023-01-30 |
Not clear |
| Antonella Zirotti Rosenberg, Maxs M\\xc3\\xa9ndez-Ruette, Mario Gorziglia, Benjam\\xc3\\xadn Alzerreca, Javiera Cabello, Sof\\xc3\\xada Kaufmann, Lukas Rambousek, Andr\\xc3\\xa9s Iturriaga Jofr\\xc3\\xa9, Ursula Wyneken, Carlos A Lafourcad. Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats. Frontiers in molecular neuroscience vol 15 issue 2022 36147210 |
temporal lobe epilepsies (tle) compromising the hippocampus are the most common form of focal epilepsies. |
2022-09-23 |
2023-01-30 |
rat |
| Peter B\\xc3\\xa4uerle, Ulf Schneider, Martin Holtkamp, Tengis Gloveli, Tamar Dugladz. Outlines to Initiate Epilepsy Surgery in Low- and Middle-Income Countries. Journal of integrative neuroscience vol 21 issue 5 2022 36137955 |
as a general outline for a new surgical epilepsy program in lmic, it is recommended to initially focus on patients with mesial temporal lobe epilepsy due to hippocampal sclerosis or other well defined pathologies. |
2022-09-22 |
2023-01-30 |
Not clear |
| Mary K McIntosh, Ron Lev. Dynamics of seizure termination in a non-human primate kindling model of mesial temporal lobe epilepsy. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference vol 2022 issue 2022 36086229 |
focal seizures with impaired awareness (fias) are commonly related to mesial temporal lobe epilepsy (mtle) with hippocampal sclerosis and potentially status epilepticus. |
2022-09-10 |
2023-01-30 |
Not clear |
| Dominique F Leitner, Sasha Devore, Juliana Laze, Daniel Friedman, James D Mills, Yan Liu, Michael Janitz, Jasper J Anink, Johannes C Baayen, Sander Idema, Erwin A van Vliet, Beate Diehl, Catherine Scott, Roland Thijs, Maromi Nei, Manor Askenazi, Shobi Sivathamboo, Terence O'Brien, Thomas Wisniewski, Maria Thom, Eleonora Aronica, Maura Boldrini, Orrin Devinsk. Serotonin Receptor Expression in Hippocampus and Temporal Cortex of TLE Patients by PGES Duration. Epilepsia vol issue 2022 36053862 |
to better understand molecular mechanisms, pges duration was correlated to 5ht1a and 5ht2a receptor protein expression and rnaseq from resected hippocampus and temporal cortex of temporal lobe epilepsy (tle) patients with seizures recorded in preoperative evaluation. |
2022-09-02 |
2023-01-30 |
Not clear |
| Irakliy Abramov, Jubran H Jubran, Lena Mary Houlihan, Marian T Park, Jacob T Howshar, Dara S Farhadi, Thanapong Loymak, Tyler S Cole, David Pitskhelauri, Mark C Preu. Multiple hippocampal transection for mesial temporal lobe epilepsy: A systematic review. Seizure vol 101 issue 2022 36041364 |
multiple hippocampal transection for mesial temporal lobe epilepsy: a systematic review. |
2022-08-30 |
2023-01-30 |
Not clear |
| Xinli Xu, Rui O Beleza, Francisco Q Gon\\xc3\\xa7alves, Sergio Valbuena, Sofia Al\\xc3\\xa7ada-Morais, N\\xc3\\xa9lio Gon\\xc3\\xa7alves, Joana Magalh\\xc3\\xa3es, Jo\\xc3\\xa3o M M Rocha, Sofia Ferreira, Ana S G Figueira, Juan Lerma, Rodrigo A Cunha, Ricardo J Rodrigues, Joana M Marque. Adenosine A Scientific reports vol 12 issue 1 2022 36038626 |
an eloquent example of adult circuit remodelling is the hippocampal mossy fiber (mf) sprouting found in diseases such as temporal lobe epilepsy. |
2022-08-29 |
2023-01-30 |
Not clear |
| Julia Taube, Juri-Alexander Witt, Alexander Grote, Daniel Delev, Jonas Enkirch, Elke Hattingen, Albert J Becker, Christian Erich Elger, Christoph Helmstaedte. Preoperative and postoperative memory in epilepsy patients with 'gliosis only' versus hippocampal sclerosis: a matched case-control study. Journal of neurology, neurosurgery, and psychiatry vol issue 2022 36008114 |
gliosis only (go) and hippocampal sclerosis (hs) are distinct histopathological entities in mesial temporal lobe epilepsy. |
2022-08-25 |
2023-01-30 |
Not clear |
| Alexander C Whitebirch, John J LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A Siegelbaum, Helen E Scharfma. Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron vol issue 2022 35987207 |
enhanced excitability of the hippocampal ca2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. |
2022-08-20 |
2023-01-30 |
mouse |
| Alexander C Whitebirch, John J LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A Siegelbaum, Helen E Scharfma. Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron vol issue 2022 35987207 |
the hippocampal ca2 region, an area important for social memory, has been suspected to play a role in temporal lobe epilepsy (tle) because of its resistance to degeneration observed in neighboring ca1 and ca3 regions in both humans and rodent models of tle. |
2022-08-20 |
2023-01-30 |
mouse |
| Am\\xc3\\xa9lie Aussel, Radu Ranta, Olivier Aron, Sophie Colnat-Coulbois, Louise Maillard, Laure Buhr. Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations. Journal of computational neuroscience vol issue 2022 35971033 |
indeed, medial temporal lobe epilepsy is associated with hippocampal abnormalities both at the neuronal (channelopathies, impaired potassium and chloride dynamics) and network level (neuronal and axonal loss, mossy fiber sprouting), with more frequent seizures during wakefulness compared with slow-wave sleep. |
2022-08-15 |
2023-01-30 |
human |
| Dalma T\\xc3\\xa9nyi, Tam\\xc3\\xa1s T\\xc3\\xa9nyi, Gy\\xc3\\xb6rgyi Cs\\xc3\\xa1bi, S\\xc3\\xa1ra Jeges, Be\\xc3\\xa1ta B\\xc3\\xb3n\\xc3\\xa9, Katalin L\\xc5\\x91rincz, Norbert Kov\\xc3\\xa1cs, J\\xc3\\xb3zsef Janszk. Increased prevalence of minor physical anomalies in patients with epilepsy. Scientific reports vol 12 issue 1 2022 35962048 |
235 patients were included, according to the following subgroups: acquired epilepsy (non-genetic, non-developmental etiology) [n\xe2\x80\x89=\xe2\x80\x8963], temporal lobe epilepsy with hippocampal sclerosis (tle with hs) [n\xe2\x80\x89=\xe2\x80\x8927], epilepsy with cortical dysgenesis etiology [n\xe2\x80\x89=\xe2\x80\x8929], cryptogenic epilepsy [n\xe2\x80\x89=\xe2\x80\x8969] and idiopathic generalized epilepsy (ige) [n\xe2\x80\x89=\xe2\x80\x8947]. |
2022-08-12 |
2023-01-30 |
human |
| Maria Zimmermann, Luciano Minuzzi, Arturo Aliaga Aliaga, Marie-Christine Guiot, Jeffery A Hall, Jean-Paul Soucy, Gassan Massarweh, Salah El Mestikawy, Pedro Rosa-Neto, Eliane Kobayash. Reduced Metabotropic Glutamate Receptor Type 5 Availability in the Epileptogenic Hippocampus: An Frontiers in neurology vol 13 issue 2022 35937057 |
reduced metabotropic glutamate receptor type 5 availability in the epileptogenic hippocampus: an abnormalities in the expression of metabotropic glutamate receptor type 5 (mglur5) have been observed in the hippocampus of patients with drug-resistant mesial temporal lobe epilepsy (mtle). |
2022-08-08 |
2023-01-30 |
Not clear |
| Dinesh Upadhya, Sahithi Attaluri, Yan Liu, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Yi Dong, Su-Chun Zhang, Ashok K Shett. Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy. NPJ Regenerative medicine vol 7 issue 1 2022 35915118 |
interneuron loss/dysfunction contributes to spontaneous recurrent seizures (srs) in chronic temporal lobe epilepsy (tle), and interneuron grafting into the epileptic hippocampus reduces srs and improves cognitive function. |
2022-08-01 |
2023-01-30 |
rat |
| Barbara Sita\\xc5\\xa1, Mihaela Bobi\\xc4\\x87-Rasonja, Goran Mrak, Sara Trnski, Magdalena Krbot Skori\\xc4\\x87, Darko Ore\\xc5\\xa1kovi\\xc4\\x87, Vinka Knezovi\\xc4\\x87, \\xc5\\xbdeljka Petelin Gad\\xc5\\xbee, Zdravko Petanjek, Goran \\xc5\\xa0imi\\xc4\\x87, Danijela Kolenc, Nata\\xc5\\xa1a Jovanov Milo\\xc5\\xa1evi\\xc4\\x8. Reorganization of the Brain Extracellular Matrix in Hippocampal Sclerosis. International journal of molecular sciences vol 23 issue 15 2022 35897768 |
in patients with drug-resistant mesial temporal lobe epilepsy (mtle), hippocampal sclerosis type 1 (hs1) is the most common histopathological finding. |
2022-07-28 |
2023-01-30 |
Not clear |
| B\\xc3\\xa1rbara Guerra Leal, Aurora Barros-Barbosa, F\\xc3\\xa1tima Ferreirinha, Jo\\xc3\\xa3o Chaves, Rui Rangel, Agostinho Santos, Cl\\xc3\\xa1udia Carvalho, Ricardo Martins-Ferreira, Raquel Sam\\xc3\\xb5es, Joel Freitas, Jo\\xc3\\xa3o Lopes, Jo\\xc3\\xa3o Ramalheira, Maria Gra\\xc3\\xa7a Lobo, Ant\\xc3\\xb3nio Martins da Silva, Paulo P Costa, Paulo Correia-de-S\\xc3\\xa. Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22. Frontiers in cellular neuroscience vol 16 issue 2022 35875355 |
mesial temporal lobe epilepsy (mtle) drug-refractoriness is associated with p2x7 receptors overexpression in the human hippocampus and temporal neocortex and may be predicted by low circulating levels of mir-22. |
2022-07-25 |
2023-01-30 |
human |
| Alexey A Kulikov, Alexandra A Naumova, Nadezhda A Dorofeeva, Andrey P Ivlev, Margarita V Glazova, Elena V Chernigovskay. Dynamics of neurodegeneration in the hippocampus of Krushinsky-Molodkina rats correlates with the progression of limbic seizures. Epilepsy & behavior : E&B vol 134 issue 2022 35849865 |
temporal lobe epilepsy is accompanied with neurodegeneration in the hippocampus, but how the cells die is not fully understood. |
2022-07-18 |
2023-01-30 |
rat |
| Dong An, Xiuting Qi, Kunpeng Li, Weixing Xu, Yue Wang, Xi Chen, Sha Sha, Chunfeng Wu, Yimei Du, Lei Che. Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus. Cellular and molecular neurobiology vol issue 2022 35840809 |
the blockage of transient receptor potential vanilloid 4 (trpv4) inhibits inflammation and reduces hippocampal neuronal injury in a pilocarpine-induced mouse model of temporal lobe epilepsy. |
2022-07-15 |
2023-01-30 |
mouse |