All Relations between Epilepsy, Temporal Lobe and hippocampus

Publication Sentence Publish Date Extraction Date Species
Peter Bedner, Alexander Dupper, Kerstin Hüttmann, Julia Müller, Michel K Herde, Pavel Dublin, Tushar Deshpande, Johannes Schramm, Ute Häussler, Carola A Haas, Christian Henneberger, Martin Theis, Christian Steinhäuse. Astrocyte uncoupling as a cause of human temporal lobe epilepsy. Brain : a journal of neurology. vol 138. issue Pt 5. 2015-07-17. PMID:25765328. in the present study we analysed functional properties of astrocytes in hippocampal specimens from patients with mesial temporal lobe epilepsy without (n = 44) and with sclerosis (n = 75) combining patch clamp recording, k(+) concentration analysis, electroencephalography/video-monitoring, and fate mapping analysis. 2015-07-17 2023-08-13 mouse
Peter Bedner, Alexander Dupper, Kerstin Hüttmann, Julia Müller, Michel K Herde, Pavel Dublin, Tushar Deshpande, Johannes Schramm, Ute Häussler, Carola A Haas, Christian Henneberger, Martin Theis, Christian Steinhäuse. Astrocyte uncoupling as a cause of human temporal lobe epilepsy. Brain : a journal of neurology. vol 138. issue Pt 5. 2015-07-17. PMID:25765328. we found that the hippocampus of patients with mesial temporal lobe epilepsy with sclerosis is completely devoid of bona fide astrocytes and gap junction coupling, whereas coupled astrocytes were abundantly present in non-sclerotic specimens. 2015-07-17 2023-08-13 mouse
Izumi Toyoda, Satoshi Fujita, Ajoy K Thamattoor, Paul S Buckmaste. Unit Activity of Hippocampal Interneurons before Spontaneous Seizures in an Animal Model of Temporal Lobe Epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904809. unit activity of hippocampal interneurons before spontaneous seizures in an animal model of temporal lobe epilepsy. 2015-07-16 2023-08-13 rat
Chun-Lei Han, Wei Hu, Matt Stead, Tan Zhang, Jian-Guo Zhang, Gregory A Worrell, Fan-Gang Men. Electrical stimulation of hippocampus for the treatment of refractory temporal lobe epilepsy. Brain research bulletin. vol 109. 2015-07-10. PMID:25200252. electrical stimulation of hippocampus for the treatment of refractory temporal lobe epilepsy. 2015-07-10 2023-08-13 Not clear
Chun-Lei Han, Wei Hu, Matt Stead, Tan Zhang, Jian-Guo Zhang, Gregory A Worrell, Fan-Gang Men. Electrical stimulation of hippocampus for the treatment of refractory temporal lobe epilepsy. Brain research bulletin. vol 109. 2015-07-10. PMID:25200252. this review is intended to provide a comprehensive review of the modern history of electrical stimulation of the hippocampus for the treatment of refractory medial temporal lobe epilepsy and discuss the anatomical basis, validity, side effects, stimulation paradigm and mechanism of hippocampus stimulation and the responsive electrical stimulation trials. 2015-07-10 2023-08-13 Not clear
Zhaohua Xiao, Jing Peng, Lifen Yang, Huimin Kong, Fei Yi. Interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the PI3K/Akt/mTOR signaling pathway in hippocampal neurons. Journal of neuroimmunology. vol 282. 2015-06-30. PMID:25903737. interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the pi3k/akt/mtor signaling pathway in hippocampal neurons. 2015-06-30 2023-08-13 rat
Parisa Goodarzi, Hamid Reza Aghayan, Masoud Soleimani, Abbas Norouzi-Javidan, Fereshteh Mohamadi-Jahani, Sharareh Jahangiri, Seyed Hasan Emami-Razavi, Bagher Larijani, Babak Arjman. Stem cell therapy for treatment of epilepsy. Acta medica Iranica. vol 52. issue 9. 2015-06-26. PMID:25325201. one of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (tle) which results from hippocampal sclerosis. 2015-06-26 2023-08-13 Not clear
Xian-Dong Meng, Dong Wei, Juan Li, Jun-Jun Kang, Chen Wu, Lei Ma, Feng Yang, Ge-Min Zhu, Tang-Peng Ou-Yang, Ying-Ying Liu, Wen Jian. Astrocytic expression of cannabinoid type 1 receptor in rat and human sclerotic hippocampi. International journal of clinical and experimental pathology. vol 7. issue 6. 2015-05-26. PMID:25031702. using the pilocarpine model of chronic spontaneous recurrent seizures, which mimics the main features of mesial temporal lobe epilepsy (tle) with hippocampal sclerosis (hs) in humans, we examined the expression of cb1r in hippocampal astrocytes of epileptic rats. 2015-05-26 2023-08-13 human
B Van Nieuwenhuyse, R Raedt, J Delbeke, W J Wadman, P Boon, K Vonc. In search of optimal DBS paradigms to treat epilepsy: bilateral versus unilateral hippocampal stimulation in a rat model for temporal lobe epilepsy. Brain stimulation. vol 8. issue 2. 2015-05-22. PMID:25554585. in search of optimal dbs paradigms to treat epilepsy: bilateral versus unilateral hippocampal stimulation in a rat model for temporal lobe epilepsy. 2015-05-22 2023-08-13 rat
Julian Tejada, Norberto Garcia-Cairasco, Antonio C Roqu. Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus. PLoS computational biology. vol 10. issue 5. 2015-05-21. PMID:24811867. temporal lobe epilepsy strongly affects hippocampal dentate gyrus granule cells morphology. 2015-05-21 2023-08-13 Not clear
Sanaz Eftekhari, Soraya Mehrabi, Mansooreh Soleimani, Gholamreza Hassanzadeh, Amene Shahrokhi, Hossein Mostafavi, Parisa Hayat, Mahmood Barati, Hajar Mehdizadeh, Reza Rahmanzadeh, Mahmoud Reza Hadjighassem, Mohammad Taghi Joghatae. BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model. Acta neurobiologiae experimentalis. vol 74. issue 3. 2015-05-15. PMID:25231847. bdnf modifies hippocampal kcc2 and nkcc1 expression in a temporal lobe epilepsy model. 2015-05-15 2023-08-13 rat
Pierre Besson, Vera Dinkelacker, Romain Valabregue, Lionel Thivard, Xavier Leclerc, Michel Baulac, Daniela Sammler, Olivier Colliot, Stéphane Lehéricy, Séverine Samson, Sophie Dupon. Structural connectivity differences in left and right temporal lobe epilepsy. NeuroImage. vol 100. 2015-05-12. PMID:24814212. our knowledge on temporal lobe epilepsy (tle) with hippocampal sclerosis has evolved towards the view that this syndrome affects widespread brain networks. 2015-05-12 2023-08-13 human
Pierre Besson, Vera Dinkelacker, Romain Valabregue, Lionel Thivard, Xavier Leclerc, Michel Baulac, Daniela Sammler, Olivier Colliot, Stéphane Lehéricy, Séverine Samson, Sophie Dupon. Structural connectivity differences in left and right temporal lobe epilepsy. NeuroImage. vol 100. 2015-05-12. PMID:24814212. we performed a whole brain connectome analysis in 39 patients with refractory temporal lobe epilepsy and unilateral hippocampal sclerosis (20 right and 19 left) and 28 healthy subjects. 2015-05-12 2023-08-13 human
Heidi Elbrønd-Bek, Janne Damm Olling, Casper R Gøtzsche, Alison Waterfield, Gitta Wörtwein, David P D Woldby. Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice. Synapse (New York, N.Y.). vol 68. issue 10. 2015-05-11. PMID:24985894. kainate-induced seizures constitute a model of temporal lobe epilepsy where prominent changes are observed in the hippocampal neuropeptide y (npy) system. 2015-05-11 2023-08-13 mouse
Silvia Zucchini, Gianluca Marucci, Beatrice Paradiso, Giovanni Lanza, Paolo Roncon, Pierangelo Cifelli, Manuela Ferracin, Marco Giulioni, Roberto Michelucci, Guido Rubboli, Michele Simonat. Identification of miRNAs differentially expressed in human epilepsy with or without granule cell pathology. PloS one. vol 9. issue 8. 2015-05-11. PMID:25148080. all patients underwent surgery for intractable temporal lobe epilepsy and had hippocampal sclerosis associated with no granule cell pathology in half of the cases and with type-2 granule cell pathology (granule cell layer dispersion or bilamination) in the other half. 2015-05-11 2023-08-13 human
Boris C Bernhardt, Seok-Jun Hong, Andrea Bernasconi, Neda Bernascon. Magnetic resonance imaging pattern learning in temporal lobe epilepsy: classification and prognostics. Annals of neurology. vol 77. issue 3. 2015-04-27. PMID:25546153. in temporal lobe epilepsy (tle), although hippocampal atrophy lateralizes the focus, the value of magnetic resonance imaging (mri) to predict postsurgical outcome is rather modest. 2015-04-27 2023-08-13 Not clear
Irena Doležalová, Milan Brázdil, Markéta Hermanová, Eva Janoušová, Robert Kub. Effect of partial drug withdrawal on the lateralization of interictal epileptiform discharges and its relationship to surgical outcome in patients with hippocampal sclerosis. Epilepsy research. vol 108. issue 8. 2015-04-20. PMID:25052709. to assess changes in the relative lateralization of interictal epileptiform discharges (ieds) and interictal eeg prognostic value in terms of surgical outcome between periods with full medication (fmp) and reduced medication (rmp) in patients with temporal lobe epilepsy (tle) associated with hippocampal sclerosis (hs). 2015-04-20 2023-08-13 Not clear
Meng Na, Yanshu Liu, Chen Shi, Wenpeng Gao, Haitao Ge, Yu Wang, Haiyang Wang, Yu Long, Hong Shen, Changbin Shi, Zhiguo Li. Prognostic value of CA4/DG volumetry with 3T magnetic resonance imaging on postoperative outcome of epilepsy patients with dentate gyrus pathology. Epilepsy research. vol 108. issue 8. 2015-04-20. PMID:25085233. hippocampal sclerosis (hs), the most common feature of mesial temporal lobe epilepsy (mtle), is widely accepted as surgical indication for refractory epilepsy. 2015-04-20 2023-08-13 Not clear
Trevor A Steve, Jeffrey D Jirsch, Donald W Gros. Quantification of subfield pathology in hippocampal sclerosis: a systematic review and meta-analysis. Epilepsy research. vol 108. issue 8. 2015-04-20. PMID:25107686. therefore, a systematic review and meta-analysis of studies reporting neuronal densities in temporal lobe epilepsy was performed in order to quantify subfield pathology in hippocampal sclerosis. 2015-04-20 2023-08-13 Not clear
Suzanne F C Miller-Delaney, Kenneth Bryan, Sudipto Das, Ross C McKiernan, Isabella M Bray, James P Reynolds, Ryder Gwinn, Raymond L Stallings, David C Henshal. Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy. Brain : a journal of neurology. vol 138. issue Pt 3. 2015-04-20. PMID:25552301. differential dna methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy. 2015-04-20 2023-08-13 human