| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher Martínez-Aguirre, Luis Alfredo Márquez, Cindy Lizbeth Santiago-Castañeda, Francia Carmona-Cruz, Maria de Los Angeles Nuñez-Lumbreras, Vladimir A Martínez-Rojas, Mario Alonso-Vanegas, Gustavo Aguado-Carrillo, Norma L Gómez-Víquez, Emilio J Galván, Manola Cuéllar-Herrera, Luisa Roch. Cannabidiol Modifies the Glutamate Over-Release in Brain Tissue of Patients and Rats with Epilepsy: A Pilot Study. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137458. |
synaptic terminals (synaptosomes) were obtained from the epileptic neocortex of patients with drug-resistant temporal lobe epilepsy (dr-tle, |
2023-12-23 |
2023-12-25 |
rat |
| Soumil Dey, Vivek Dubey, Aparna Banerjee Dixit, Manjari Tripathi, Poodipedi Sarat Chandra, Jyotirmoy Banerje. Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy. Cells. vol 11. issue 22. 2022-11-26. PMID:36428989. |
differential levels of tryptophan-kynurenine pathway metabolites in the hippocampus, anterior temporal lobe, and neocortex in an animal model of temporal lobe epilepsy. |
2022-11-26 |
2023-08-14 |
rat |
| Robyn M Busch, Lamis Yehia, Ingmar Blümcke, Bo Hu, Richard Prayson, Bruce P Hermann, Imad M Najm, Charis En. Molecular and subregion mechanisms of episodic memory phenotypes in temporal lobe epilepsy. Brain communications. vol 4. issue 6. 2022-11-24. PMID:36419965. |
here, we use spatial quantitation to examine differential expression of targeted proteins and transcripts in four brain regions essential for episodic memory (dentate gyrus, ca3, ca1, neocortex) between temporal lobe epilepsy patients with and without episodic memory impairment. |
2022-11-24 |
2023-08-14 |
Not clear |
| Balagopal Pai, Jessica Tome-Garcia, Wan Sze Cheng, German Nudelman, Kristin G Beaumont, Saadi Ghatan, Fedor Panov, Elodia Caballero, Kwadwo Sarpong, Lara Marcuse, Jiyeoun Yoo, Yan Jiang, Anne Schaefer, Schahram Akbarian, Robert Sebra, Dalila Pinto, Elena Zaslavsky, Nadejda M Tsankov. High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy. Acta neuropathologica communications. vol 10. issue 1. 2022-10-24. PMID:36274170. |
in this study, we validated a method that simultaneously isolates neuronal (neun +), astrocyte (pax6 + neun-), and oligodendroglial progenitor (opc) (olig2 + neun-) enriched nuclei populations from non-diseased, fresh-frozen human neocortex and then applied it to characterize the distinct transcriptomes of such populations isolated from electrode-mapped temporal lobe epilepsy (tle) surgical samples. |
2022-10-24 |
2023-08-14 |
human |
| b' B\\xc3\\xa1rbara Guerra Leal, Aurora Barros-Barbosa, F\\xc3\\xa1tima Ferreirinha, Jo\\xc3\\xa3o Chaves, Rui Rangel, Agostinho Santos, Cl\\xc3\\xa1udia Carvalho, Ricardo Martins-Ferreira, Raquel Sam\\xc3\\xb5es, Joel Freitas, Jo\\xc3\\xa3o Lopes, Jo\\xc3\\xa3o Ramalheira, Maria Gra\\xc3\\xa7a Lobo, Ant\\xc3\\xb3nio Martins da Silva, Paulo P Costa, Paulo Correia-de-S\\xc3\\xa. Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22. Frontiers in cellular neuroscience. vol 16. 2022-07-25. PMID:35875355.' |
mesial temporal lobe epilepsy (mtle) drug-refractoriness is associated with p2x7 receptors overexpression in the human hippocampus and temporal neocortex and may be predicted by low circulating levels of mir-22. |
2022-07-25 |
2023-08-14 |
human |
| Burcu A Pazarlar, Sanjay S Aripaka, Viktor Petukhov, Lars Pinborg, Konstantin Khodosevich, Jens D Mikkelse. Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE). Molecular brain. vol 15. issue 1. 2022-05-16. PMID:35578248. |
expression profile of synaptic vesicle glycoprotein 2a, b, and c paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (tle). |
2022-05-16 |
2023-08-13 |
human |
| Burcu A Pazarlar, Sanjay S Aripaka, Viktor Petukhov, Lars Pinborg, Konstantin Khodosevich, Jens D Mikkelse. Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE). Molecular brain. vol 15. issue 1. 2022-05-16. PMID:35578248. |
we have here analyzed the expression of sv2 genes in neuronal subtypes in the temporal neocortex in selected specimens by using single nucleus-rna sequencing, and performed quantitative pcr in populations of temporal lobe epilepsy (tle) patients and healthy controls. |
2022-05-16 |
2023-08-13 |
human |
| Vivek Dubey, Soumil Dey, Aparna Banerjee Dixit, Manjari Tripathi, P Sarat Chandra, Jyotirmoy Banerje. Differential glutamate receptor expression and function in the hippocampus, anterior temporal lobe and neocortex in a pilocarpine model of temporal lobe epilepsy. Experimental neurology. vol 347. 2021-12-03. PMID:34752784. |
differential glutamate receptor expression and function in the hippocampus, anterior temporal lobe and neocortex in a pilocarpine model of temporal lobe epilepsy. |
2021-12-03 |
2023-08-13 |
rat |
| Lipeng Cheng, Yue Xing, Herui Zhang, Ru Liu, Huanling Lai, Yueshan Piao, Wei Wang, Xiaoming Yan, Xiaonan Li, Jiaoyang Wang, Donghong Li, Horace H Loh, Tao Yu, Guojun Zhang, Xiaofeng Yan. Mechanistic Analysis of Micro-Neurocircuits Underlying the Epileptogenic Zone in Focal Cortical Dysplasia Patients. Cerebral cortex (New York, N.Y. : 1991). 2021-10-19. PMID:34664065. |
epileptic and relatively non-epileptic temporal neocortex specimens were resected from fcd and mesial temporal lobe epilepsy (mtle) patients, respectively. |
2021-10-19 |
2023-08-13 |
Not clear |
| Xi Lu, Min Yang, Yong Yang, Xue-Feng Wan. Atlastin-1 modulates seizure activity and neuronal excitability. CNS neuroscience & therapeutics. vol 26. issue 3. 2021-06-30. PMID:31729196. |
here, we reported that the expression level of atlastin-1 protein was reduced in the temporal neocortex of patients with temporal lobe epilepsy and in the hippocampus and adjacent cortex of a pentylenetetrazol-kindled epileptic mouse model. |
2021-06-30 |
2023-08-13 |
mouse |
| Diana Organista-Juárez, Adriana Jiménez, Luisa Rocha, Mario Alonso-Vanegas, Rosalinda Guevara-Guzmá. Differential expression of miR-34a, 451, 1260, 1275 and 1298 in the neocortex of patients with mesial temporal lobe epilepsy. Epilepsy research. vol 157. 2020-07-23. PMID:31470144. |
differential expression of mir-34a, 451, 1260, 1275 and 1298 in the neocortex of patients with mesial temporal lobe epilepsy. |
2020-07-23 |
2023-08-13 |
Not clear |
| José Luis Castañeda-Cabral, Carlos Beas-Zárate, Luisa L Rocha-Arrieta, Sandra A Orozco-Suárez, Mario Alonso-Vanegas, Rosalinda Guevara-Guzmán, Mónica E Ureña-Guerrer. Increased protein expression of VEGF-A, VEGF-B, VEGF-C and their receptors in the temporal neocortex of pharmacoresistant temporal lobe epilepsy patients. Journal of neuroimmunology. vol 328. 2019-11-29. PMID:30597392. |
increased protein expression of vegf-a, vegf-b, vegf-c and their receptors in the temporal neocortex of pharmacoresistant temporal lobe epilepsy patients. |
2019-11-29 |
2023-08-13 |
human |
| Fady Girgis, Madeline E Greil, Philip S Fastenau, Jennifer Sweet, Hans Lüders, Jonathan P Mille. Resection of Temporal Neocortex During Multiple Hippocampal Transections for Mesial Temporal Lobe Epilepsy Does not Affect Seizure or Memory Outcome. Operative neurosurgery (Hagerstown, Md.). vol 13. issue 6. 2019-07-10. PMID:29186594. |
resection of temporal neocortex during multiple hippocampal transections for mesial temporal lobe epilepsy does not affect seizure or memory outcome. |
2019-07-10 |
2023-08-13 |
Not clear |
| Joey S J Smeets, Astrid M H Horstman, Olaf E M G Schijns, Jim T A Dings, Govert Hoogland, Annemie P Gijsen, Joy P B Goessens, Freek G Bouwman, Will K W H Wodzig, Edwin C Mariman, Luc J C van Loo. Brain tissue plasticity: protein synthesis rates of the human brain. Brain : a journal of neurology. vol 141. issue 4. 2019-06-28. PMID:29432531. |
here, we applied stable isotope methodology to directly assess protein synthesis rates in neocortex and hippocampus tissue of six patients undergoing temporal lobectomy for drug-resistant temporal lobe epilepsy (clinical trial registration: ntr5147). |
2019-06-28 |
2023-08-13 |
human |
| Adam R Neumann, Robrecht Raedt, Hendrik W Steenland, Mathieu Sprengers, Katarzyna Bzymek, Zaneta Navratilova, Lilia Mesina, Jeanne Xie, Valerie Lapointe, Fabian Kloosterman, Kristl Vonck, Paul A J M Boon, Ivan Soltesz, Bruce L McNaughton, Artur Lucza. Involvement of fast-spiking cells in ictal sequences during spontaneous seizures in rats with chronic temporal lobe epilepsy. Brain : a journal of neurology. vol 140. issue 9. 2017-10-30. PMID:29050390. |
we used simultaneous recordings from multiple neurons in the hippocampus and neocortex of rats with chronic temporal lobe epilepsy to demonstrate that subsets of cells discharge in a highly stereotypical sequential pattern during ictal events, and that these stereotypical patterns were reproducible across consecutive seizures. |
2017-10-30 |
2023-08-13 |
rat |
| Yunyi Huang, Xuling Wu, Jing Guo, Jinxian Yua. Myocyte-specific enhancer binding factor 2A expression is downregulated during temporal lobe epilepsy. The International journal of neuroscience. vol 126. issue 9. 2017-04-28. PMID:26439092. |
mef2a expression was detected in 20 temporal neocortex tissue samples from patients with temporal lobe epilepsy (tle) and 20 samples from trauma patients without epilepsy by real-time quantitative polymerase chain reaction, immunohistochemistry, double-label immunofluorescent staining, and western blot analysis. |
2017-04-28 |
2023-08-13 |
rat |
| Ivette Bañuelos-Cabrera, Manola Cuéllar-Herrera, Ana Luisa Velasco, Francisco Velasco, Mario Alonso-Vanegas, Francia Carmona, Rosalinda Guevara, José-Antonio Arias-Montaño, Luisa Roch. Pharmacoresistant temporal lobe epilepsy modifies histamine turnover and H3 receptor function in the human hippocampus and temporal neocortex. Epilepsia. vol 57. issue 4. 2016-08-18. PMID:26915454. |
pharmacoresistant temporal lobe epilepsy modifies histamine turnover and h3 receptor function in the human hippocampus and temporal neocortex. |
2016-08-18 |
2023-08-13 |
human |
| Ivette Bañuelos-Cabrera, Manola Cuéllar-Herrera, Ana Luisa Velasco, Francisco Velasco, Mario Alonso-Vanegas, Francia Carmona, Rosalinda Guevara, José-Antonio Arias-Montaño, Luisa Roch. Pharmacoresistant temporal lobe epilepsy modifies histamine turnover and H3 receptor function in the human hippocampus and temporal neocortex. Epilepsia. vol 57. issue 4. 2016-08-18. PMID:26915454. |
experiments were designed to evaluate the tissue content of tele-methylhistamine (t-meha) and histamine as well as h3 receptor (h3 rs) binding and activation of the heterotrimeric guanine nucleotide binding αi/o proteins (gαi/o) coupled to these receptors in the hippocampus and temporal neocortex of patients (n = 10) with pharmacoresistant mesial temporal lobe epilepsy (mtle). |
2016-08-18 |
2023-08-13 |
human |
| Takehiro Uda, Michiharu Morino, Noriaki Minami, Takahiro Matsumoto, Tatsuya Uchida, Takamasa Kame. Abnormal discharges from the temporal neocortex after selective amygdalohippocampectomy and seizure outcomes. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 22. issue 11. 2016-07-04. PMID:26256064. |
the present study examined the relationship between residual discharges from the temporal neocortex postoperatively and seizure outcomes, in mesial temporal lobe epilepsy (mtle) patients with hippocampal sclerosis (hs) who were treated with selective amygdalohippocampectomy (selah). |
2016-07-04 |
2023-08-13 |
Not clear |
| B O Estupiñán-Díaz, L M Morales-Chacón, I García-Maeso, L Lorigados-Pedre, M Báez-Martín, M E García-Navarro, O Trápaga-Quincoses, N Quintanal-Cordero, J Prince-López, J E Bender-del Bust. Corpora amylacea in the neocortex in patients with temporal lobe epilepsy and focal cortical dysplasia. Neurologia (Barcelona, Spain). vol 30. issue 2. 2016-02-29. PMID:25440067. |
corpora amylacea in the neocortex in patients with temporal lobe epilepsy and focal cortical dysplasia. |
2016-02-29 |
2023-08-13 |
Not clear |