All Relations between Epilepsy and Sudden Unexpected Death in Epilepsy

Publication Sentence Publish Date Extraction Date Species
Jo Sourbron, Lieven Laga. Fenfluramine: a plethora of mechanisms? Frontiers in pharmacology. vol 14. 2023-05-30. PMID:37251322. the antiseizure medication (asm) fenfluramine is an effective treatment for reducing seizure frequency, ameliorating comorbidities, and potentially reducing risk of sudden unexpected death in epilepsy (sudep) in patients with dravet syndrome and lennox-gastaut syndrome, among other rare epilepsies. 2023-05-30 2023-08-14 Not clear
Guilherme Loureiro Fialho, Richard L Verrier, Andre D'Avila, Hiago Murilo Melo, Peter Wolf, Roger Walz, Katia Li. Dual assessment of abnormal cardiac electrical dispersion and diastolic dysfunction for early detection of the epileptic heart condition. Journal of electrocardiology. vol 78. 2023-02-22. PMID:36805647. sudden unexpected death in epilepsy (sudep) is among the most important causes of death in these individuals and possibly, sudden cardiac death (scd) in epilepsy is also as important. 2023-02-22 2023-08-14 Not clear
Jennifer Bauer, Orrin Devinsky, Markus Rothermel, Henner Koc. Autonomic dysfunction in epilepsy mouse models with implications for SUDEP research. Frontiers in neurology. vol 13. 2023-01-23. PMID:36686527. sudden unexpected death in epilepsy (sudep) is the leading cause of death in drug-resistant epilepsy and most often results from respiratory and cardiac impairments due to brainstem dysfunction. 2023-01-23 2023-08-14 mouse
Ian C Wenker, Alexis R Boscia, Christine Lewis, Anas Tariq, Raquel Miralles, Jessica C Hanflink, Priyanka Saraf, Manoj K Pate. Forebrain epileptiform activity is not required for seizure-induced apnea in a mouse model of Frontiers in neural circuits. vol 16. 2022-09-26. PMID:36160949. forebrain epileptiform activity is not required for seizure-induced apnea in a mouse model of sudden unexpected death in epilepsy (sudep) accounts for the deaths of 8-17% of patients with epilepsy. 2022-09-26 2023-08-14 mouse
Sneha Kumari, Divyani Garg, Suvasini Sharma, Harish Kumar Pemd. Effect of counselling of parents of children with epilepsy focusing on sudden unexpected death in epilepsy. Epilepsy research. vol 186. 2022-08-15. PMID:35970090. to characterize the effects of sudden unexpected death in epilepsy (sudep) counselling on epilepsy-related childcare behaviour and practices, and emotional distress, measured by the depression, anxiety and stress scale-21 (dass-21), among parents of children with epilepsy (cwe), and to obtain feedback about sudep counselling. 2022-08-15 2023-08-14 Not clear
Dominique F Leitner, Evgeny Kanshin, Manor Askenazi, Arline Faustin, Daniel Friedman, Sasha Devore, Beatrix Ueberheide, Thomas Wisniewski, Orrin Devinsk. Raphe and ventrolateral medulla proteomics in epilepsy and sudden unexpected death in epilepsy. Brain communications. vol 4. issue 4. 2022-08-05. PMID:35928051. to understand the potential role of brainstem nuclei in sudden unexpected death in epilepsy, we evaluated molecular signalling pathways using localized proteomics in microdissected midbrain dorsal raphe and medial medullary raphe serotonergic nuclei, as well as the ventrolateral medulla in brain tissue from epilepsy patients who died of sudden unexpected death in epilepsy and other causes in diverse epilepsy syndromes and non-epilepsy control cases ( 2022-08-05 2023-08-14 Not clear
Dominique F Leitner, Evgeny Kanshin, Manor Askenazi, Arline Faustin, Daniel Friedman, Sasha Devore, Beatrix Ueberheide, Thomas Wisniewski, Orrin Devinsk. Raphe and ventrolateral medulla proteomics in epilepsy and sudden unexpected death in epilepsy. Brain communications. vol 4. issue 4. 2022-08-05. PMID:35928051. raphe and ventrolateral medulla proteomics in epilepsy and sudden unexpected death in epilepsy. 2022-08-05 2023-08-14 Not clear
Alexandre Bacq, Delphine Roussel, Thomas Bonduelle, Sara Zagaglia, Marina Maletic, Théo Ribierre, Homa Adle-Biassette, Cécile Marchal, Mélanie Jennesson, Isabelle An, Fabienne Picard, Vincent Navarro, Sanjay M Sisodiya, Stéphanie Baula. Cardiac Investigations in Sudden Unexpected Death in DEPDC5-Related Epilepsy. Annals of neurology. 2021-11-16. PMID:34693554. germline loss-of-function mutations in depdc5, and in its binding partners (nprl2/3) of the mammalian target of rapamycin (mtor) repressor gator1 complex, cause focal epilepsies and increase the risk of sudden unexpected death in epilepsy (sudep). 2021-11-16 2023-08-13 Not clear
Kanitpong Phabphal, Prut Koonalintip, Pasiri Sithinamsuwan, Krongthong Wongsritrang, Thanyalak Amornpojnimman, Nichanan Ekpitakdamrong, Alan F Geate. Obstructive sleep apnea and sudden unexpected death in epilepsy in unselected patients with epilepsy: are they associated? Sleep & breathing = Schlaf & Atmung. vol 25. issue 4. 2021-11-15. PMID:33580841. we aimed to determine (1) the frequency of high-risk sudden unexpected death in epilepsy (sudep) in patients with epilepsy who have had obstructive sleep apnea (osa) in different stages of sleep using the revised sudep risk inventory (rsudep-7) score instrument and (2) the factors associated with high risk sudep in patients with epilepsy who have had osa. 2021-11-15 2023-08-13 Not clear
Megan S Crotts, YuJaung Kim, Eduardo Bravo, George B Richerson, Frida A Tera. A ketogenic diet protects DBA/1 and Scn1a Epilepsy & behavior : E&B. vol 124. 2021-11-15. PMID:34600281. a ketogenic diet protects dba/1 and scn1a patients with uncontrolled epilepsy have a high risk of sudden unexpected death in epilepsy (sudep). 2021-11-15 2023-08-13 Not clear
Jana Velíšková, Christopher Marra, Yue Liu, Akshay Shekhar, David S Park, Vasilisa Iatckova, Ying Xie, Glenn I Fishman, Libor Velíšek, Mitchell Goldfar. Early onset epilepsy and sudden unexpected death in epilepsy with cardiac arrhythmia in mice carrying the early infantile epileptic encephalopathy 47 gain-of-function FHF1(FGF12) missense mutation. Epilepsia. vol 62. issue 7. 2021-10-15. PMID:33982289. early onset epilepsy and sudden unexpected death in epilepsy with cardiac arrhythmia in mice carrying the early infantile epileptic encephalopathy 47 gain-of-function fhf1(fgf12) missense mutation. 2021-10-15 2023-08-13 mouse
Vicenta Salanova, Michael R Sperling, Robert E Gross, Chris P Irwin, Jim A Vollhaber, Jonathon E Giftakis, Robert S Fishe. The SANTÉ study at 10 years of follow-up: Effectiveness, safety, and sudden unexpected death in epilepsy. Epilepsia. vol 62. issue 6. 2021-10-08. PMID:33830503. we evaluated the efficacy and safety of deep brain anterior thalamus stimulation after 7 and 10 years, and report the incidence of sudden unexpected death in epilepsy (sudep) and overall mortality in adults in the stimulation of the anterior nucleus of the thalamus for epilepsy (santÉ) study. 2021-10-08 2023-08-13 Not clear
Jocelyn Y Chen. Risk of sudden unexpected death in people with epilepsy and obstructive sleep apnea. Epilepsy research. vol 176. 2021-09-20. PMID:34352639. this study aimed to determine whether severity of newly diagnosed obstructive sleep apnea (osa) in people with epilepsy is associated with elevated sudden unexpected death in epilepsy (sudep) risk as calculated by the revised sudep-7 inventory (rsudep-7). 2021-09-20 2023-08-13 human
Xinyue Zhang, Li Cui, Weihong Li. Cardiac Arrest in Frontal Lobe Epilepsy: A Potential Cause of Sudden Unexpected Death in Epilepsy. Neurology India. vol 69. issue 3. 2021-06-28. PMID:34169879. cardiac arrest in frontal lobe epilepsy: a potential cause of sudden unexpected death in epilepsy. 2021-06-28 2023-08-13 Not clear
Yukun Yuan, Heather A O'Malley, Melissa A Smaldino, Alexandra A Bouza, Jacob M Hull, Lori L Iso. Delayed maturation of GABAergic signaling in the Scn1a and Scn1b mouse models of Dravet Syndrome. Scientific reports. vol 9. issue 1. 2020-11-03. PMID:30996233. dravet syndrome (ds) is a catastrophic developmental and epileptic encephalopathy characterized by severe, pharmacoresistant seizures and the highest risk of sudden unexpected death in epilepsy (sudep) of all epilepsy syndromes. 2020-11-03 2023-08-13 mouse
Fu-Shan Kuo, Colin M Cleary, Joseph J LoTurco, Xinnian Chen, Daniel K Mulke. Disordered breathing in a mouse model of Dravet syndrome. eLife. vol 8. 2020-02-24. PMID:31025941. dravet syndrome (ds) is a form of epilepsy with a high incidence of sudden unexpected death in epilepsy (sudep). 2020-02-24 2023-08-13 mouse
Inge C M Loonen, Nico A Jansen, Stuart M Cain, Maarten Schenke, Rob A Voskuyl, Andrew C Yung, Barry Bohnet, Piotr Kozlowski, Roland D Thijs, Michel D Ferrari, Terrance P Snutch, Arn M J M van den Maagdenberg, Else A Tolne. Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice. Brain : a journal of neurology. vol 142. issue 2. 2019-09-19. PMID:30649209. sudden unexpected death in epilepsy (sudep) is a fatal complication of epilepsy in which brainstem spreading depolarization may play a pivotal role, as suggested by animal studies. 2019-09-19 2023-08-13 mouse
Stephanie L Vanhoof-Villalba, Nicole M Gautier, Vikas Mishra, Edward Glasscoc. Pharmacogenetics of KCNQ channel activation in 2 potassium channelopathy mouse models of epilepsy. Epilepsia. vol 59. issue 2. 2018-10-26. PMID:29265344. here, we examined the therapeutic efficacy of kcnq channel activation by retigabine in preventing seizures and neurocardiac dysfunction in 2 potassium channelopathy mouse models of epilepsy with differing severity that have been associated with increased risk of sudden unexpected death in epilepsy (sudep): the kcna1 2018-10-26 2023-08-13 mouse
Barbara Mostacci, Francesca Bisulli, Luca Vignatelli, Laura Licchetta, Lidia Di Vito, Claudia Rinaldi, Irene Trippi, Lorenzo Ferri, Giuseppe Plazzi, Federica Provini, Paolo Tinupe. Incidence of sudden unexpected death in epilepsy in sleep-related hypermotor epilepsy, formerly named nocturnal frontal lobe epilepsy. Sleep medicine. vol 29. 2018-09-04. PMID:27915205. incidence of sudden unexpected death in epilepsy in sleep-related hypermotor epilepsy, formerly named nocturnal frontal lobe epilepsy. 2018-09-04 2023-08-13 Not clear
Adam Strzelczyk, Gerda Zschebek, Sebastian Bauer, Christoph Baumgartner, Martin Grond, Anke Hermsen, Matthias Kieslich, Günter Krämer, Gerhard Kurlemann, Theodor W May, Thomas Mayer, Bernd A Neubauer, Margarete Pfäfflin, Barbara Plecko, Philippe Ryvlin, Susanne Schubert-Bast, Hermann Stefan, Eugen Trinka, Susanne Knake, Carola Seifart, Felix Roseno. Predictors of and attitudes toward counseling about SUDEP and other epilepsy risk factors among Austrian, German, and Swiss neurologists and neuropediatricians. Epilepsia. vol 57. issue 4. 2016-08-18. PMID:26899504. to examine the attitudes toward counseling about sudden unexpected death in epilepsy (sudep) and other epilepsy risk factors among austrian, german, and swiss neurologists and neuropediatricians, and to determine factors associated with not discussing sudep. 2016-08-18 2023-08-13 Not clear