All Relations between Movement Disorders and substantia nigra compacta

Publication Sentence Publish Date Extraction Date Species
Sarah Hui, Jimmy George, Minesh Kapadia, Hien Chau, Zahn Bariring, Rebecca Earnshaw, Kashfia Shafiq, Lorraine V Kalia, Suneil K Kali. Mitophagy Upregulation Occurs Early in the Neurodegenerative Process Mediated by α-Synuclein. Molecular neurobiology. 2024-04-06. PMID:38581539. parkinson's disease (pd) is a progressive neurogenerative movement disorder characterized by dopaminergic cell death within the substantia nigra pars compacta (snpc) due to the aggregation-prone protein α-synuclein. 2024-04-06 2024-04-10 human
Kandatege Wimalasena, Oluwatosin Adetuyi, Maya Eldan. Metabolic energy decline coupled dysregulation of catecholamine metabolism in physiologically highly active neurons: implications for selective neuronal death in Parkinson's disease. Frontiers in aging neuroscience. vol 16. 2024-03-07. PMID:38450382. parkinson's disease (pd) is an age-related irreversible neurodegenerative disease which is characterized as a progressively worsening involuntary movement disorder caused by the loss of dopaminergic (da) neurons in substantia nigra pars compacta (snpc). 2024-03-07 2024-03-09 Not clear
Line Duborg Skou, Steffi Krudt Johansen, Justyna Okarmus, Morten Meye. Pathogenesis of DJ-1/PARK7-Mediated Parkinson's Disease. Cells. vol 13. issue 4. 2024-02-23. PMID:38391909. parkinson's disease (pd) is a common movement disorder associated with the degeneration of dopaminergic neurons in the substantia nigra pars compacta. 2024-02-23 2024-02-25 Not clear
Shinya Okuda, Norihito Uemura, Masanori Sawamura, Tomoyuki Taguchi, Masashi Ikuno, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahash. Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 19. issue 1. 2024-01-04. PMID:38176797. parkinson's disease (pd), the most common neurodegenerative movement disorder, is characterized by dopaminergic neuron loss in the substantia nigra pars compacta (snpc) and intraneuronal α-synuclein (α-syn) inclusions. 2024-01-04 2024-01-07 mouse
Sandra Moceri, Natascha Bäuerle, Johanna Habermeyer, Veronika Ratz-Wirsching, Julia Harrer, Jörg Distler, Anja Schulze-Krebs, Ivanna K Timotius, Alexandra Bluhm, Maike Hartlage-Rübsamen, Steffen Roßner, Jürgen Winkler, Wei Xiang, Stephan von Hörste. Young human alpha synuclein transgenic (BAC-SNCA) mice display sex- and gene-dose-dependent phenotypic disturbances. Behavioural brain research. 2023-12-03. PMID:38043677. parkinson's disease (pd) is a common neurodegenerative movement disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of aggregated alpha synuclein (asyn). 2023-12-03 2023-12-10 mouse
Jongkyun Kang, Guodong Huang, Long Ma, Youren Tong, Phoenix Chen, Jie She. Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival. bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873418. mutations in leucine-rich repeat kinase 2 (lrrk2) are the most common genetic cause of parkinson's disease (pd), which is the leading neurodegenerative movement disorder characterized by the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc). 2023-10-24 2023-11-08 Not clear
Sheikh Azimullah, Mohamed Fizur Nagoor Meeran, Khatija Ayoob, Seenipandi Arunachalam, Shreesh Ojha, Rami Beira. Tannic Acid Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Inhibiting Inflammation, Oxidative Stress, Apoptosis, and Glutamate Toxicity in Rats. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373023. parkinson's disease (pd), a movement disorder, is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) region of the brain. 2023-06-28 2023-08-14 human
Tahereh Sohrabi, Behnaz Mirzaei-Behbahani, Ramin Zadali, Mitra Pirhaghi, Ludmilla A Morozova-Roche, Ali Akbar Merata. Common Mechanisms Underlying α-Synuclein-Induced Mitochondrial Dysfunction in Parkinson's Disease. Journal of molecular biology. 2023-02-03. PMID:36736886. parkinson's disease (pd) is the most common neurological movement disorder characterized by the selective and irreversible loss of dopaminergic neurons in substantia nigra pars compacta resulting in dopamine deficiency in the striatum. 2023-02-03 2023-08-14 Not clear
Manuj Ahuja, Navneet Ammal Kaidery, Debashis Dutta, Otis C Attucks, Eliot H Kazakov, Irina Gazaryan, Mitsuyo Matsumoto, Kazuhiko Igarashi, Sudarshana M Sharma, Bobby Thoma. Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson's Disease. Antioxidants (Basel, Switzerland). vol 11. issue 9. 2022-09-23. PMID:36139853. parkinson's disease (pd) is the second most common neurodegenerative movement disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. 2022-09-23 2023-08-14 human
Katarzyna Kaczyńska, Magdalena Ewa Orłowska, Kryspin Andrzejewsk. Respiratory Abnormalities in Parkinson's Disease: What Do We Know from Studies in Humans and Animal Models? International journal of molecular sciences. vol 23. issue 7. 2022-04-12. PMID:35408858. parkinson's disease (pd) is the second most common progressive neurodegenerative disease characterized by movement disorders due to the progressive loss of dopaminergic neurons in the ventrolateral region of the substantia nigra pars compacta (snpc). 2022-04-12 2023-08-13 human
Shinya Okuda, Norihito Uemura, Masanori Sawamura, Tomoyuki Taguchi, Masashi Ikuno, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahash. Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2021-12-22. PMID:34935120. parkinson's disease (pd), the most common neurodegenerative movement disorder, is characterized by dopaminergic neuron loss in the substantia nigra pars compacta (snpc) and intraneuronal α-synuclein (α-syn) inclusions. 2021-12-22 2023-08-13 mouse
Sanghyun Park, Jeong-Eun Yoo, Gyu-Bum Yeon, Jin Hee Kim, Jae Souk Lee, Sung Kyoung Choi, Young-Gi Hwang, Chan Wook Park, Myung Soo Cho, Jongwan Kim, Dokyun Na, Hyung Wook Kim, Dae-Sung Kim, Dong-Wook Ki. Trophoblast glycoprotein is a new candidate gene for Parkinson's disease. NPJ Parkinson's disease. vol 7. issue 1. 2021-12-08. PMID:34876581. parkinson's disease (pd) is a movement disorder caused by progressive degeneration of the midbrain dopaminergic (mda) neurons in the substantia nigra pars compacta (snc). 2021-12-08 2023-08-13 mouse
Daniel A Xu, Timothy P DeYoung, Nicholas P Kondoleon, Roderic G Eckenhoff, Maryellen F Eckenhof. Anesthetic Effects on the Progression of Parkinson Disease in the Rat DJ-1 Model. Anesthesia and analgesia. vol 133. issue 5. 2021-11-22. PMID:34673725. parkinson disease is a chronic and progressive movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2021-11-22 2023-08-13 rat
Bárbara Mendes-Pinheiro, Carina Soares-Cunha, Ana Marote, Eduardo Loureiro-Campos, Jonas Campos, Sandra Barata-Antunes, Daniela Monteiro-Fernandes, Diogo Santos, Sara Duarte-Silva, Luísa Pinto, António José Salgad. Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response. International journal of molecular sciences. vol 22. issue 21. 2021-11-18. PMID:34768962. parkinson's disease (pd) is a prevalent movement disorder characterized by the progressive loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2021-11-18 2023-08-13 mouse
Isaac Deng, Frances Corrigan, Guangxi Zhai, Xin-Fu Zhou, Larisa Bobrovskay. Lipopolysaccharide animal models of Parkinson's disease: Recent progress and relevance to clinical disease. Brain, behavior, & immunity - health. vol 4. 2021-10-01. PMID:34589845. parkinson's disease (pd) is one of the most common neurodegenerative movement disorders which is characterised neuropathologically by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and the presence of lewy bodies (made predominately of α-synuclein) in the surviving neurons. 2021-10-01 2023-08-13 human
Albert Frank Magnusen, Shelby Loraine Hatton, Reena Rani, Manoj Kumar Pande. Genetic Defects and Pro-inflammatory Cytokines in Parkinson's Disease. Frontiers in neurology. vol 12. 2021-07-10. PMID:34239490. parkinson's disease (pd) is a movement disorder attributed to the loss of dopaminergic (da) neurons mainly in the substantia nigra pars compacta. 2021-07-10 2023-08-13 Not clear
Haigang Ren, Wanqing Zhai, Xiaojun Lu, Guanghui Wan. The Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson's Disease. Frontiers in aging neuroscience. vol 13. 2021-06-26. PMID:34168552. parkinson's disease (pd) is the most common neurodegenerative movement disorder, and it is characterized by the selective loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc), as well as the presence of intracellular inclusions with α-synuclein as the main component in surviving da neurons. 2021-06-26 2023-08-13 Not clear
Bianca Marchett. Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's disease. Redox biology. vol 36. 2021-06-18. PMID:32863224. oxidative stress and inflammation have long been recognized to contribute to parkinson's disease (pd), a common movement disorder characterized by the selective loss of midbrain dopaminergic neurons (mdan) of the substantia nigra pars compacta (snpc). 2021-06-18 2023-08-13 mouse
Inma Castilla-Cortázar, Gabriel A Aguirre, Giovana Femat-Roldán, Irene Martín-Estal, Luis Espinos. Is insulin-like growth factor-1 involved in Parkinson's disease development? Journal of translational medicine. vol 18. issue 1. 2021-05-14. PMID:32046737. parkinson's disease (pd) is a neurodegenerative disorder that results in the death of dopaminergic neurons within the substantia nigra pars compacta and the reduction in dopaminergic control over striatal output neurons, leading to a movement disorder most commonly characterized by akinesia or bradykinesia, rigidity and tremor. 2021-05-14 2023-08-13 Not clear
Nadine J Ortne. Voltage-Gated Ca Frontiers in synaptic neuroscience. vol 13. 2021-03-16. PMID:33716705. voltage-gated ca the loss of dopamine (da)-producing neurons in the substantia nigra pars compacta (sn) underlies the core motor symptoms of the progressive movement disorder parkinson's disease (pd). 2021-03-16 2023-08-13 Not clear