All Relations between Narcolepsy and nt1

Publication Sentence Publish Date Extraction Date Species
Takashi Ishikawa, Hiroe Hara, Ayumi Kawano, Haruhide Kimur. Danavorexton, a selective orexin 2 receptor agonist, provides a symptomatic improvement in a narcolepsy mouse model. Pharmacology, biochemistry, and behavior. 2022-09-15. PMID:36108771. narcolepsy type 1 (nt1), caused by loss of orexin neurons, is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, disrupted nighttime sleep, hypnagogic/hypnopompic hallucinations and sleep paralysis, as well as a high risk of obesity. 2022-09-15 2023-08-14 mouse
Silvia Melzi, Vincent Prevot, Christelle Peyro. Precocious puberty in narcolepsy type 1: Orexin loss and/or neuroinflammation, which is to blame? Sleep medicine reviews. 2022-09-12. PMID:36096986. narcolepsy type 1 (nt1) is a rare neurological sleep disorder triggered by postnatal loss of the orexin/hypocretin neuropeptides. 2022-09-12 2023-08-14 Not clear
Rebecca Evans, Haruhide Kimura, Robert Alexander, Ceri H Davies, Hélène Faessel, Deborah S Hartman, Takashi Ishikawa, Emiliangelo Ratti, Kohei Shimizu, Motohisa Suzuki, Shinichiro Tanaka, Hiroshi Yukitake, Yves Dauvilliers, Emmanuel Migno. Orexin 2 receptor-selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 35. 2022-08-22. PMID:35994639. narcolepsy type 1 (nt1) is a sleep disorder caused by a loss of orexinergic neurons. 2022-08-22 2023-08-14 mouse
Guo Luo, Jing Zhang, Ling Lin, Emmanuel Jean-Marie Migno. Characterization of T cell receptors reactive to HCRT Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 32. 2022-08-01. PMID:35914171. characterization of t cell receptors reactive to hcrt narcolepsy type 1 (nt1), a disorder caused by hypocretin/orexin (hcrt) cell loss, is associated with human leukocyte antigen (hla)-dq0602 (98%) and t cell receptor (tcr) polymorphisms. 2022-08-01 2023-08-14 human
Makoto Honda, Yosuke Shigematsu, Mihoko Shimada, Yoshiko Honda, Katsushi Tokunaga, Taku Miyagaw. Low carnitine palmitoyltransferase1 activity is a risk factor for narcolepsy type 1 and other hypersomnia. Sleep. 2022-07-10. PMID:35810398. narcolepsy type 1 (nt1) is associated with metabolic abnormalities but their etiology remains largely unknown. 2022-07-10 2023-08-14 Not clear
Shan Qu, Peipei Wang, Mengmeng Wang, Chenyang Li, Xiaosong Dong, Liyue Xu, Fang Ha. A comparison of mood, quality of life and executive function among narcolepsy type 1 patients with or without ADHD symptoms in China. Sleep medicine. vol 97. 2022-06-19. PMID:35717731. to investigate the prevalence of core attention-deficit/hyperactivity disorder (adhd) symptoms in chinese narcolepsy type 1 (nt1) patients and to explore mood, quality of life, and executive function in narcolepsy patients with or without adhd and the response to methylphenidate hydrochloride extended-release tablets (er-mph) treatment. 2022-06-19 2023-08-14 Not clear
Zhongxing Zhang, Yves Dauvilliers, Giuseppe Plazzi, Geert Mayer, Gert Jan Lammers, Joan Santamaria, Markku Partinen, Sebastiaan Overeem, Rafael Del Rio Villegas, Karel Sonka, Rosa Peraita-Adrados, Raphaël Heinzer, Aleksandra Wierzbicka, Birgit Högl, Mauro Manconi, Eva Feketeova, Antonio Martins da Silva, Jitka Bušková, Claudio L A Bassetti, Lucie Barateau, Fabio Pizza, Elena Antelmi, Jari K Gool, Rolf Fronczek, Carles Gaig, Ramin Khatam. Idling for Decades: A European Study on Risk Factors Associated with the Delay Before a Narcolepsy Diagnosis. Nature and science of sleep. vol 14. 2022-06-07. PMID:35669411. narcolepsy type-1 (nt1) is a rare chronic neurological sleep disorder with excessive daytime sleepiness (eds) as usual first and cataplexy as pathognomonic symptom. 2022-06-07 2023-08-14 Not clear
Amanda Asp, Frida Lund, Christian Benedict, Pontus Waslin. Impaired procedural memory in narcolepsy type 1. Acta neurologica Scandinavica. 2022-06-02. PMID:35652281. here, we investigated whether sleep-dependent memory consolidation differs between healthy subjects and narcolepsy type 1 (nt1) patients. 2022-06-02 2023-08-14 human
Kunihiro Futenma, Yoshikazu Takaesu, Masaki Nakamura, Kenichi Hayashida, Noboru Takeuchi, Yuichi Inou. Metabolic-Syndrome-Related Comorbidities in Narcolepsy Spectrum Disorders: A Preliminary Cross-Sectional Study in Japan. International journal of environmental research and public health. vol 19. issue 10. 2022-05-28. PMID:35627822. narcolepsy types 1 (nt1) and 2 (nt2) and idiopathic hypersomnia (ih) are thought to be a disease continuum known as narcolepsy spectrum disorders (nsds). 2022-05-28 2023-08-13 Not clear
Adrienne Elisabeth van der Hoeven, Rolf Fronczek, Mink Sebastian Schinkelshoek, Frederik Willem Cornelis Roelandse, Jaap Adriaan Bakker, Sebastiaan Overeem, Denise Bijlenga, Gert Jan Lammer. Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1. Sleep. vol 45. issue 5. 2022-05-13. PMID:35554594. the diagnosis of narcolepsy type 1 (nt1) is based upon the presence of cataplexy and/or a cerebrospinal fluid (csf) hypocretin-1/orexin-a level ≤ 110 pg/ml. 2022-05-13 2023-08-13 Not clear
Adrienne Elisabeth van der Hoeven, Kevin van Waaij, Denise Bijlenga, Frederik Willem Cornelis Roelandse, Sebastiaan Overeem, Jaap Adriaan Bakker, Rolf Fronczek, Gert Jan Lammer. Hypocretin-1 measurements in cerebrospinal fluid using radioimmunoassay: within and between assay reliability and limit of quantification. Sleep. 2022-05-05. PMID:35512685. the most sensitive and specific investigative method for the diagnosis of narcolepsy type 1 (nt1) is the determination of hypocretin-1 (orexin a) deficiency (≤110 pg/ml) in cerebrospinal fluid using a radioimmunoassay (ria). 2022-05-05 2023-08-13 Not clear
Utku Ogan Akyildiz, F Irsel Tezer, Guray Koc, Sevda Ismailogullari, Aylin Bican Demir, Aysin Kisabay Ak, Gulin Sunter, Kezban Aslan Kara, Deniz Tuncel Berktas, Aysenur Sahin, Filiz Azman, Bulent Devrim Akcay, Duygu Kurt Gok, Hikmet Yilmaz, Kadriye Agan, Yavuz Bekmezci, Sinan Yetkin, Murat Aksu, Derya Karadeniz, Gulcin Benbir Sene. The REM-sleep-related characteristics of narcolepsy: a nation-wide multicenter study in Turkey, the REMCON study. Sleep medicine. vol 94. 2022-04-21. PMID:35447401. narcolepsy type 1 (nt1) is caused by hypocretin deficiency, the pathophysiology of narcolepsy type 2 (nt2) has not been delineated. 2022-04-21 2023-08-13 Not clear
Sébastien Arthaud, Manon Villalba, Camille Blondet, Anne-Laure Morel, Christelle Peyro. Effects of sex and estrous cycle on sleep and cataplexy in narcoleptic mice. Sleep. 2022-04-16. PMID:35429396. narcolepsy type 1 (nt1) is a rare neurology disorder caused by the loss of orexin/hypocretin neurons. 2022-04-16 2023-08-13 mouse
Sally El Sammak, Veronica Cipriani, Ashima Sahni, Hrayr Attaria. Narcolepsy type 1 comorbid with Myasthenia Gravis: possible immunological link. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2022-04-08. PMID:35393935. narcolepsy type 1 (nt1) has a probable autoimmune pathophysiology. 2022-04-08 2023-08-13 Not clear
Pablo Medrano-Martínez, Ángela Gómez-Sacristan, Rosa Peraita-Adrado. Is memory impaired in narcolepsy type 1? Journal of sleep research. 2022-04-07. PMID:35388527. memory deficits in narcolepsy with cataplexy type 1 (nt1) have been poorly studied, and the results are controversial. 2022-04-07 2023-08-13 human
Ye Zhang, Rong Ren, Linghui Yang, Haipeng Zhang, Yuan Shi, Michael V Vitiello, Xiangdong Tang, Larry D Sanfor. Comparative polysomnography parameters between narcolepsy type 1/type 2 and idiopathic hypersomnia: A systematic review and meta-analysis. Sleep medicine reviews. vol 63. 2022-03-12. PMID:35278894. a meta-analysis exploring polysomnography (psg) differences between narcolepsy type 1 (nt1)/type 2 (nt2) and idiopathic hypersomnia (ih), particularly one that stratifies the analysis by ih with and without long sleep time (lst), could provide information useful for appropriately re-classifying the central disorders of hypersomnolence. 2022-03-12 2023-08-13 Not clear
Lucie Barateau, Régis Lopez, Sofiene Chenini, Anna Laura Rassu, Lytissia Mouhli, Cloé Dhalluin, Isabelle Jaussent, Yves Dauvillier. Linking clinical complaints and objective measures of Disrupted Nighttime Sleep in Narcolepsy type 1. Sleep. 2022-03-11. PMID:35275598. despite its high frequency in narcolepsy type 1(nt1), disrupted nocturnal sleep (dns) remains understudied, and its determinants have been poorly assessed. 2022-03-11 2023-08-13 Not clear
Louise Piilgaard, Laura Rose, Camille Gylling Hviid, Kristi A Kohlmeier, Birgitte Rahbek Kornu. Sex-related differences within sleep-wake dynamics, cataplexy, and EEG fast-delta power in a narcolepsy mouse model. Sleep. 2022-03-10. PMID:35266540. narcolepsy type 1 (nt1) is a sleep-wake disorder caused by selective loss of hypocretin (hcrt, also called orexin) neurons. 2022-03-10 2023-08-13 mouse
Adrienne Elisabeth van der Hoeven, Rolf Fronczek, Mink Sebastian Schinkelshoek, Frederik Willem Cornelis Roelandse, Jaap Adriaan Bakker, Sebastiaan Overeem, Denise Bijlenga, Gert Jan Lammer. Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1. Sleep. 2022-03-07. PMID:35255144. the diagnosis of narcolepsy type 1 (nt1) is based upon the presence of cataplexy and/or a cerebrospinal fluid (csf) hypocretin-1/orexin-a level ≤110 pg/ml. 2022-03-07 2023-08-13 Not clear
Yu Sun, Ryan Tisdale, Sunmee Park, Shun-Chieh Ma, Jasmine Heu, Meghan Haire, Giancarlo Allocca, Akihiro Yamanaka, Stephen R Morairty, Thomas S Kilduf. The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female Orexin/tTA; TetO-DTA Mice. Sleep. 2022-02-19. PMID:35182424. narcolepsy type 1 (nt1), a sleep disorder with similar prevalence in both sexes, is thought to be due to loss of the hypocretin/orexin (hcrt) neurons. 2022-02-19 2023-08-13 mouse