| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mihika Gangolli, Sinisa Pajevic, Joong Hee Kim, Elizabeth B Hutchinson, Dan Benjamini, Peter J Basse. Correspondence of mean apparent propagator MRI metrics with phosphorylated tau and astrogliosis in chronic traumatic encephalopathy. Brain communications. vol 5. issue 5. 2023-10-30. PMID:37901038. |
chronic traumatic encephalopathy is a neurodegenerative disease that is diagnosed and staged based on the localization and extent of phosphorylated tau pathology. |
2023-10-30 |
2023-11-08 |
Not clear |
| Terjahna Richards, Jeanette C Perron, Ketan Patel, John Wurpel, Sandra E Reznik, Francis Schann. Therapeutic Intervention of Neuroinflammatory Alzheimer Disease Model by Inhibition of Classical Complement Pathway with the Use of Anti-C1r Loaded Exosomes. Research square. 2023-10-27. PMID:37886595. |
alzheimer's disease (ad) is a complex neurodegenerative disease associated with memory decline, cognitive impairment, amyloid plaque formation and tau tangles. |
2023-10-27 |
2023-11-08 |
Not clear |
| Dong-Hwi Kim, Da-Yoon Kim, Kyu-Sung Kim, Sang-Hoon Han, Hyeon-Jeong Go, Jae-Hyeong Kim, Kyu-Beom Lim, Dong-Hun Lee, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, Yang-Kyu Choi, Yeun-Kyung Shin, Oh-Kyu Kwon, Do-Geun Kim, In-Soo Cho. Neurologic Effects of SARS-CoV-2 Transmitted among Dogs. Emerging infectious diseases. vol 29. issue 11. 2023-10-26. PMID:37877548. |
furthermore, we detected phosphorylated tau, a marker of neurodegenerative disease, indicating a potential link between sars-cov-2-associated small vessel disease and neurodegeneration. |
2023-10-26 |
2023-11-08 |
dog |
| Abigail R Esquivel, Shannon E Hill, Laura J Blai. DnaJs are enriched in tau regulators. International journal of biological macromolecules. vol 253. issue Pt 7. 2023-10-26. PMID:37852393. |
the aberrant accumulation of tau protein is implicated as a pathogenic factor in many neurodegenerative diseases. |
2023-10-26 |
2023-11-08 |
Not clear |
| Ester Piovesana, Claudia Magrin, Matteo Ciccaldo, Martina Sola, Manolo Bellotto, Maurizio Molinari, Stéphanie Papin, Paolo Paganett. Tau accumulation in degradative organelles is associated to lysosomal stress. Scientific reports. vol 13. issue 1. 2023-10-21. PMID:37865674. |
considering the presence of tau lesions in parkinson's disease as well as in multiple neurodegenerative disorders including alzheimer's disease, our data call for further studies on strategies to alleviate alp dysfunction as new therapeutic opportunity for neurodegenerative diseases and lsd. |
2023-10-21 |
2023-11-08 |
human |
| Matthew J Benskey, Spencer Panoushek, Takashi Saito, Takaomi C Saido, Tessa Grabinski, Nicholas M Kanaa. Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse. Frontiers in aging neuroscience. vol 15. 2023-10-16. PMID:37842124. |
tau is a microtubule-associated protein with a diverse functional repertoire linked to neurodegenerative disease. |
2023-10-16 |
2023-11-08 |
mouse |
| Mingyue Jin, Shengming Wang, Xiaodie Gao, Zhenyou Zou, Shinji Hirotsune, Liyuan Su. Pathological and physiological functional cross-talks of α-synuclein and tau in the central nervous system. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843221. |
in this review, we provide a summary of the recent findings on the functional roles of α-synuclein and tau in the physiological conditions and pathogenesis of neurodegenerative diseases. |
2023-10-16 |
2023-11-08 |
mouse |
| Mingyue Jin, Shengming Wang, Xiaodie Gao, Zhenyou Zou, Shinji Hirotsune, Liyuan Su. Pathological and physiological functional cross-talks of α-synuclein and tau in the central nervous system. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843221. |
a deep understanding of the interplay between α-synuclein and tau in physiological and pathological conditions might provide novel targets for clinical diagnosis and therapeutic strategies to treat neurodegenerative diseases. |
2023-10-16 |
2023-11-08 |
mouse |
| Jiaxin Hu, Wenchi Sha, Shuangshuang Yuan, Jiarui Wu, Yunpeng Huan. Aggregation, Transmission, and Toxicity of the Microtubule-Associated Protein Tau: A Complex Comprehension. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834471. |
tau protein aggregates can be found in a number of devastating neurodegenerative diseases known as "tauopathies", such as alzheimer's disease (ad), frontotemporal dementia (ftd), corticobasal degeneration (cbd), etc. |
2023-10-14 |
2023-10-15 |
Not clear |
| Syed Jawad Ali Shah, Qianqian Zhang, Jingjing Guo, Hongli Liu, Huanxiang Liu, Jordi Villà-Freix. Identification of Aggregation Mechanism of Acetylated PHF6* and PHF6 Tau Peptides Based on Molecular Dynamics Simulations and Markov State Modeling. ACS chemical neuroscience. 2023-10-13. PMID:37830541. |
however, tau's dysfunction and accumulation in the human brain can lead to several neurodegenerative diseases, such as alzheimer's disease, down's syndrome, and frontotemporal dementia. |
2023-10-13 |
2023-10-15 |
human |
| Delsuz Rezaee, Fatemeh Saadatpour, Nayyereh Akbari, Anahita Zoghi, Sajad Najafi, Parisa Beiranvand, Fahimeh Zamani-Rarani, Mohammad Amin Rashidi, Saeid Bagheri-Mohammadi, Mohammad Bakhtiar. The role of microRNAs in the pathophysiology of human central nervous system: A focus on neurodegenerative diseases. Ageing research reviews. 2023-10-13. PMID:37832609. |
they are particularly known to affect the amyloid β (aβ) cleavage and accumulation, tau protein homeostasis, and expression of alpha-synuclein (α-syn), parkin, pink1, and brain-derived neurotrophic factor (bdnf) that play pivotal roles in the pathogenesis of neurodegenerative diseases. |
2023-10-13 |
2023-10-15 |
human |
| Benjamin C Creekmore, Ryohei Watanabe, Edward B Le. Neurodegenerative Disease Tauopathies. Annual review of pathology. 2023-10-13. PMID:37832941. |
tauopathies are a diverse group of progressive and fatal neurodegenerative diseases characterized by aberrant tau inclusions in the central nervous system. |
2023-10-13 |
2023-10-15 |
Not clear |
| Kyu Won Oh, Dong-Kyu Kim, Ao-Lin Hsu, Seung-Jae Le. Distinct sets of lysosomal genes define synucleinopathy and tauopathy. BMB reports. 2023-10-11. PMID:37817435. |
neurodegenerative diseases are characterized by distinct protein aggregates, such as those of α-synuclein and tau. |
2023-10-11 |
2023-10-15 |
caenorhabditis_elegans |
| Alejandra Del Carmen Alonso, Abdeslem El Idrissi, Robert Candia, Viktoriya Morozova, Frida Esther Kleima. Tau: More than a microtubule-binding protein in neurons. Cytoskeleton (Hoboken, N.J.). 2023-10-11. PMID:37819542. |
even with tau's rise to stardom as a central player in neurodegenerative disease, therapeutic efforts have largely been targeted toward cytoskeletal changes. |
2023-10-11 |
2023-10-15 |
Not clear |
| Oscar B Akide Ndunge, Henry J Shikani, Minxian Dai, Brandi D Freeman, Mahalia S Desruisseau. Effects of anti-tau immunotherapy on reactive microgliosis, cerebral endotheliopathy, and cognitive function in an experimental model of cerebral malaria. Journal of neurochemistry. 2023-10-10. PMID:37814468. |
abnormal regulation of tau, an axonal protein pathologically associated with the formation of neurofibrillary lesions in neurodegenerative diseases, has been linked to inflammation and cerebral microvascular compromise and has been reported in human and experimental cm (ecm). |
2023-10-10 |
2023-10-15 |
mouse |
| Oscar B Akide Ndunge, Henry J Shikani, Minxian Dai, Brandi D Freeman, Mahalia S Desruisseau. Effects of anti-tau immunotherapy on reactive microgliosis, cerebral endotheliopathy, and cognitive function in an experimental model of cerebral malaria. Journal of neurochemistry. 2023-10-10. PMID:37814468. |
immunotherapy with a monoclonal antibody to pathological tau (phf-1 mab) in experimental models of neurodegenerative diseases has been reported to mitigate cognitive decline. |
2023-10-10 |
2023-10-15 |
mouse |
| Ngoc-Han Thi Nguyen, Ji Hun Kim, Su-Min Lee, Byung-Kwan Cho, Yang-Hoon Kim, Jiho Mi. Inhibition of Tau Phosphorylation and Aβ Accumulation by S. cerevisiae-derived Vacuoles in LPS-Induced SH-SY5Y Cells. Journal of biotechnology. 2023-09-30. PMID:37777088. |
neurodegenerative diseases, such as alzheimer's disease (ad), are characterized by the accumulation of intracellular tau and amyloid beta (aβ) proteins, which lead to neuroinflammation and neuronal apoptosis. |
2023-09-30 |
2023-10-07 |
Not clear |
| Patrick W Cullinane, Sarah Wrigley, Teisha Y Bradshaw, Karen Shaw, Samuel Shribman, Eduardo de Pablo Fernandez, Thomas T Warner, Zane Jaunmuktan. Late Presentation of Chronic Traumatic Encephalopathy in a Former Association Football Player. Movement disorders clinical practice. vol 10. issue 9. 2023-09-29. PMID:37772307. |
chronic traumatic encephalopathy (cte) is a neurodegenerative disease characterized by widespread accumulation of hyperphosphorylated tau that typically occurs in people who have suffered repetitive head impacts. |
2023-09-29 |
2023-10-07 |
Not clear |
| Laura Vidal-Palencia, Cristina Font, Agustín Rebollada-Merino, Gabriel Santpere, Pol Andrés-Benito, Isidro Ferrer, Martí Pumarol. Primary Feline Tauopathy: Clinical, Morphological, Immunohistochemical, and Genetic Studies. Animals : an open access journal from MDPI. vol 13. issue 18. 2023-09-28. PMID:37760385. |
tauopathies are a group of neurodegenerative diseases characterized by the pathological aggregation of hyperphosphorylated tau in neurons and glia. |
2023-09-28 |
2023-10-07 |
cat |
| Giavanna Paterno, Jose Torrellas, Brach M Bell, Kimberly-Marie M Gorion, Stephan S Quintin, Gabriela P Hery, Stefan Prokop, Benoit I Giasso. Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37761979. |
tau proteins within the adult central nervous system (cns) are found to be abnormally aggregated into heterogeneous filaments in neurodegenerative diseases, termed tauopathies. |
2023-09-28 |
2023-10-07 |
Not clear |