| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fazeleh Etebar, Damien G Harkin, Anthony R White, Samantha J Dand. Non-invasive Frontiers in cellular neuroscience. vol 18. 2024-02-13. PMID:38348116. |
in neurodegenerative diseases, microglia undergo functional changes and can have both protective and pathogenic roles. |
2024-02-13 |
2024-02-15 |
Not clear |
| Zezhong Lv, Lixi Chen, Ping Chen, Huipai Peng, Yi Rong, Wei Hong, Qiang Zhou, Nan Li, Boxing Li, Rosa C Paolicelli, Yang Zha. Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective. Neuron. 2024-02-01. PMID:38295790. |
in neurodegenerative diseases, including alzheimer's disease (ad), microglia undergo morphological and functional alterations. |
2024-02-01 |
2024-02-04 |
Not clear |
| Seamus A McRae, Christy M Richards, Dylan E Da Silva, Ishvin Riar, Sijie Shirley Yang, Noah E Zurfluh, Julien Gibon, Andis Klegeri. Pro-neuroinflammatory and neurotoxic potential of extracellular histones H1 and H3. Neuroscience research. 2024-01-26. PMID:38278218. |
inhibition of the damp-like effects of extracellular histones on microglia and their neurotoxic activity represents a potential strategy for combating neurodegenerative diseases that are characterized by the adverse activation of microglia and neuronal death. |
2024-01-26 |
2024-01-29 |
Not clear |
| Ana Beatriz DePaula-Silv. The Contribution of Microglia and Brain-Infiltrating Macrophages to the Pathogenesis of Neuroinflammatory and Neurodegenerative Diseases during TMEV Infection of the Central Nervous System. Viruses. vol 16. issue 1. 2024-01-23. PMID:38257819. |
the contribution of microglia and brain-infiltrating macrophages to the pathogenesis of neuroinflammatory and neurodegenerative diseases during tmev infection of the central nervous system. |
2024-01-23 |
2024-01-25 |
mouse |
| Lionel A Rodriguez, Matthew Nguyen Tran, Renee Garcia-Flores, Seyun Oh, Robert A Phillips, Elizabeth A Pattie, Heena R Divecha, Sun Hong Kim, Joo Heon Shin, Yong Kyu Lee, Carly Montoya, Andrew E Jaffe, Leonardo Collado-Torres, Stephanie C Page, Keri Martinowic. TrkB-dependent regulation of molecular signaling across septal cell types. Translational psychiatry. vol 14. issue 1. 2024-01-23. PMID:38263132. |
upregulated genes are enriched in ls microglia, associated with immune response and inflammation, and linked to both neurodegenerative disease and neuropsychiatric disorders. |
2024-01-23 |
2024-01-26 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
new insight on microglia activation in neurodegenerative diseases and therapeutics. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
microglia are immune cells within the central nervous system (cns) closely linked to brain health and neurodegenerative diseases such as alzheimer's disease and parkinson's disease. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
several factors, example for circadian rhythm disruption and the development of neurodegenerative diseases, influence microglia activation. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
circadian rhythm disruption affects microglia activation and, consequently, neurodegenerative diseases. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
in addition, we found that abnormal microglia activation is a common feature of neurodegenerative diseases and an essential factor of disease development. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
here we highlight the importance of microglia activation in neurodegenerative diseases. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
targeting microglia for neurodegenerative disease treatment is a promising direction. |
2024-01-08 |
2024-01-10 |
Not clear |
| Yucong Xu, Wei Gao, Yingnan Sun, Minghua W. New insight on microglia activation in neurodegenerative diseases and therapeutics. Frontiers in neuroscience. vol 17. 2024-01-08. PMID:38188026. |
we introduce the progress of methods targeting microglia for the treatment of neurodegenerative diseases and summarize the progress of drugs developed with microglia as targets, hoping to provide new ideas for treating neurodegenerative diseases. |
2024-01-08 |
2024-01-10 |
Not clear |
| Ali Tawbeh, Quentin Raas, Mounia Tahri-Joutey, Céline Keime, Romain Kaiser, Doriane Trompier, Boubker Nasser, Emma Bellanger, Marie Dessard, Yannick Hamon, Alexandre Benani, Francesca Di Cara, Tânia Cunha Alves, Johannes Berger, Isabelle Weinhofer, Stéphane Mandard, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Catherine Gondcaille, Stéphane Savar. Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation. Frontiers in molecular neuroscience. vol 16. 2024-01-02. PMID:38164407. |
microglia are crucial for brain homeostasis, and dysfunction of these cells is a key driver in most neurodegenerative diseases, including peroxisomal leukodystrophies. |
2024-01-02 |
2024-01-05 |
Not clear |
| Erica Tagliatti, Genni Desiato, Sara Mancinelli, Matteo Bizzotto, Maria C Gagliani, Elisa Faggiani, Rebeca Hernández-Soto, Andrea Cugurra, Paola Poliseno, Matteo Miotto, Rafael J Argüello, Fabia Filipello, Katia Cortese, Raffaella Morini, Simona Lodato, Michela Matteol. Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development. Immunity. 2023-12-30. PMID:38159572. |
triggering receptor expressed on myeloid cells 2 (trem2) is a myeloid cell-specific gene expressed in brain microglia, with variants that are associated with neurodegenerative diseases, including alzheimer's disease. |
2023-12-30 |
2024-01-05 |
Not clear |
| Chaoyi Li, Huakun Wang, Yu Tang, Junjiao W. Characterization of the circRNA Landscape in Interleukin-4 Induced Anti-Inflammatory Microglia. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137460. |
microglia are resident innate immune cells that play an essential role in the development and surveillance of the central nervous system as well as the shared pathogenesis of neurodegenerative diseases. |
2023-12-23 |
2023-12-25 |
Not clear |
| Anjila Dongol, Xi Chen, Peng Zheng, Zehra Boz Seyhan, Xu-Feng Huan. Quinolinic acid impairs mitophagy promoting microglia senescence and poor healthspan in C. elegans: a mechanism of impaired aging process. Biology direct. vol 18. issue 1. 2023-12-21. PMID:38124116. |
senescent microglia are a distinct microglial phenotype present in aging brain that have been implicated in the progression of aging and age-related neurodegenerative diseases. |
2023-12-21 |
2023-12-23 |
caenorhabditis_elegans |
| Justin L Bollinger, Matthew J Horchar, Eric S Wohle. Repeated activation of pyramidal neurons in the prefrontal cortex alters microglial phenotype in male mice. The Journal of pharmacology and experimental therapeutics. 2023-12-21. PMID:38129124. |
aberrant neuronal activity in the cortex alters microglia phenotype and function in several contexts, including chronic psychological stress and neurodegenerative disease. |
2023-12-21 |
2023-12-24 |
mouse |
| Yan Wang, Limei Cui, He Zhao, Huhuifen He, Liang Chen, Xicheng Song, Dawei Liu, Jingjing Qiu, Yan Su. Exploring the Connectivity of Neurodegenerative Diseases: Microglia as the Center. Journal of inflammation research. vol 16. 2023-12-19. PMID:38107384. |
exploring the connectivity of neurodegenerative diseases: microglia as the center. |
2023-12-19 |
2023-12-21 |
Not clear |
| Yan Wang, Limei Cui, He Zhao, Huhuifen He, Liang Chen, Xicheng Song, Dawei Liu, Jingjing Qiu, Yan Su. Exploring the Connectivity of Neurodegenerative Diseases: Microglia as the Center. Journal of inflammation research. vol 16. 2023-12-19. PMID:38107384. |
this review discussed the specific mechanisms underlying microglia in neurodegenerative diseases, age-related hearing loss, alzheimer's disease, parkinson's disease, and peripheral nervous system (pns) degenerative diseases. |
2023-12-19 |
2023-12-21 |
Not clear |