All Relations between Neurodegenerative Diseases and substantia nigra compacta

Publication Sentence Publish Date Extraction Date Species
Zhihui Wan, Junxuan Xu, Yunpeng Huang, Yanhong Zhai, Zhijun Ma, Bing Zhou, Zheng Ca. Elevating bioavailable iron levels in mitochondria suppresses the defective phenotypes caused by PINK1 loss-of-function in Drosophila melanogaster. Biochemical and biophysical research communications. vol 532. issue 2. 2021-03-18. PMID:32873392. parkinson's disease (pd) is the second most common progressive neurodegenerative disease, which is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2021-03-18 2023-08-13 drosophila_melanogaster
Richard L Jayaraj, Rami Beiram, Sheikh Azimullah, Nagoor Meeran Mf, Shreesh K Ojha, Abdu Adem, Fakhreya Yousuf Jala. Valeric Acid Protects Dopaminergic Neurons by Suppressing Oxidative Stress, Neuroinflammation and Modulating Autophagy Pathways. International journal of molecular sciences. vol 21. issue 20. 2021-02-25. PMID:33081327. parkinson's disease, the second common neurodegenerative disease is clinically characterized by degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) with upregulation of neuroinflammatory markers and oxidative stress. 2021-02-25 2023-08-13 rat
Dominika Fričová, Jennifer A Korchak, Abba C Zubai. Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson's disease. NPJ Regenerative medicine. vol 5. issue 1. 2021-02-13. PMID:33298940. parkinson's disease (pd) is the second most common neurodegenerative disease characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta and the presence of lewy bodies, which gives rise to motor and non-motor symptoms. 2021-02-13 2023-08-13 Not clear
Alexandre Vallée, Yves Lecarpentier, Rémy Guillevin, Jean-Noël Vallé. Circadian rhythms, Neuroinflammation and Oxidative Stress in the Story of Parkinson's Disease. Cells. vol 9. issue 2. 2021-02-12. PMID:32012898. parkinson's disease (pd) is one of the main neurodegenerative disease characterized by a progressive degeneration of neurons constituted by dopamine in the substantia nigra pars compacta. 2021-02-12 2023-08-13 Not clear
Mohammad Najim Uddin, Mohammad Injamul Hoq, Israt Jahan, Shafayet Ahmed Siddiqui, Chayan Dhar Clinton, Mohammed Ibrahim, Mohammad Safiqul Islam, Md Jakari. The mechanistic role of thymoquinone in Parkinson's disease: focus on neuroprotection in pre-clinical studies. Current molecular pharmacology. 2021-01-06. PMID:33402092. parkinson's disease (pd) is a long-term neurodegenerative disease with movement difficulties, and the common feature of neurodegeneration in pd patients is caused by dopaminergic neural damage in the substantia nigra pars compacta. 2021-01-06 2023-08-13 Not clear
Claudio Giuliano, Francesca Siani, Liudmila Mus, Cristina Ghezzi, Silvia Cerri, Barbara Pacchetti, Chiara Bigogno, Fabio Blandin. Neuroprotective effects of lignan 7-hydroxymatairesinol (HMR/lignan) in a rodent model of Parkinson's disease. Nutrition (Burbank, Los Angeles County, Calif.). vol 69. 2020-12-23. PMID:31586482. parkinson's disease (pd) is a neurodegenerative disease characterized by loss of dopaminergic neurons in the substantia nigra pars compacta (snc). 2020-12-23 2023-08-13 rat
Irving Parra, Isabel Martínez, Gabriel Ramírez-García, Yousef Tizabi, Liliana Mendiet. Differential Effects of LPS and 6-OHDA on Microglia's Morphology in Rats: Implications for Inflammatory Model of Parkinson's Disease. Neurotoxicity research. vol 37. issue 1. 2020-12-21. PMID:31478124. parkinson's disease (pd) is an idiopathic and progressive neurodegenerative disease characterized by the loss of ~ 80% of dopaminergic neurons in substantia nigra pars compacta (snpc). 2020-12-21 2023-08-13 rat
Tsu-Kung Lin, Kai-Jung Lin, Kai-Lieh Lin, Chia-Wei Liou, Shang-Der Chen, Yao-Chung Chuang, Pei-Wen Wang, Jiin-Haur Chuang, Tzu-Jou Wan. When Friendship Turns Sour: Effective Communication Between Mitochondria and Intracellular Organelles in Parkinson's Disease. Frontiers in cell and developmental biology. vol 8. 2020-12-18. PMID:33330511. parkinson's disease (pd) is a complex neurodegenerative disease with pathological hallmarks including progressive neuronal loss from the substantia nigra pars compacta and α-synuclein intraneuronal inclusions, known as lewy bodies. 2020-12-18 2023-08-13 human
Ji Wang, Fushun Wang, Dongmei Mai, Shaogang Q. Molecular Mechanisms of Glutamate Toxicity in Parkinson's Disease. Frontiers in neuroscience. vol 14. 2020-12-17. PMID:33324150. parkinson's disease (pd) is a common neurodegenerative disease, the pathological features of which include the presence of lewy bodies and the neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta. 2020-12-17 2023-08-13 Not clear
Yan Yang, Fancong Kong, Qingqing Ding, Ying Cai, Yanlei Hao, Beisha Tan. Bruceine D elevates Nrf2 activation to restrain Parkinson's disease in mice through suppressing oxidative stress and inflammatory response. Biochemical and biophysical research communications. vol 526. issue 4. 2020-11-25. PMID:32321640. parkinson's disease (pd) is neurodegenerative disease, featured by a loss of dopaminergic neurons in the substantia nigra pars compacta (snpc), characteristic motor symptoms and cognitive impairment. 2020-11-25 2023-08-13 mouse
Shulei Lei, Robert Power. NMR Metabolomics Analysis of Parkinson's Disease. Current Metabolomics. vol 1. issue 3. 2020-09-30. PMID:26078917. parkinson's disease (pd) is a neurodegenerative disease, which is characterized by progressive death of dopaminergic neurons in the substantia nigra pars compacta. 2020-09-30 2023-08-13 Not clear
Xian-Si Zeng, Wen-Shuo Geng, Jin-Jing Jia, Lei Chen, Peng-Peng Zhan. Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29719505. the disease is the second most common neurodegenerative disease characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. 2020-09-30 2023-08-13 Not clear
Bing Wang, Cun-Jin Su, Teng-Teng Liu, Yan Zhou, Yu Feng, Ya Huang, Xu Liu, Zhi-Hong Wang, Li-Hua Chen, Wei-Feng Luo, Tong Li. The Neuroprotection of Low-Dose Morphine in Cellular and Animal Models of Parkinson's Disease Through Ameliorating Endoplasmic Reticulum (ER) Stress and Activating Autophagy. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:29731707. parkinson's disease (pd) is a common neurodegenerative disease characterized the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snc). 2020-09-30 2023-08-13 Not clear
Jin-Sun Park, Yea-Hyun Leem, Jung-Eun Park, Do-Yeon Kim, Hee-Sun Ki. Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson's Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways. Biomolecules & therapeutics. vol 27. issue 2. 2020-09-30. PMID:30739428. parkinson's disease is a neurodegenerative disease characterized by the progressive loss of dopaminergic neurons within the substantia nigra pars compacta. 2020-09-30 2023-08-13 mouse
Sabyasachi Chakraborty, Satyabrata Aich, Hee-Cheol Ki. Detection of Parkinson's Disease from 3T T1 Weighted MRI Scans Using 3D Convolutional Neural Network. Diagnostics (Basel, Switzerland). vol 10. issue 6. 2020-09-28. PMID:32545609. parkinson's disease is a neurodegenerative disease that affects the aging population and is caused by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snc). 2020-09-28 2023-08-13 human
Yanjun Huang, Lirong Sun, Shuzhen Zhu, Liu Xu, Shuhu Liu, Chunhua Yuan, Yanwu Guo, Xuemin Wan. Neuroprotection Against Parkinson's Disease Through the Activation of Akt/GSK3β Signaling Pathway by Tovophyllin A. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32742256. neuroprotection against parkinson's disease through the activation of akt/gsk3β signaling pathway by tovophyllin a. parkinson's disease (pd) is one of the most prevalent and life-threatening neurodegenerative disease and mainly characterized by lack of sufficient dopaminergic neurons in the substantia nigra pars compacta (snc). 2020-09-28 2023-08-13 Not clear
Mustafa T Ardah, Madiha Mohieldin Merghani, M Emdadul Haqu. Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates α-synuclein aggregation in vitro. Neurochemistry international. vol 128. 2020-04-24. PMID:31028778. parkinson's disease (pd) is a common neurodegenerative disease characterized by progressive dopaminergic neurodegeneration with a concomitant increase in oxidative stress and neuroinflammation in the substantia nigra pars compacta (snc). 2020-04-24 2023-08-13 mouse
Swetha Pavani Rao, Neelam Sharma, Shasi V Kalivend. Embelin averts MPTP-induced dysfunction in mitochondrial bioenergetics and biogenesis via activation of SIRT1. Biochimica et biophysica acta. Bioenergetics. vol 1861. issue 3. 2020-04-06. PMID:31987812. parkinson's disease (pd) is a chronic neurodegenerative disease characterized by the death of dopamine neurons of substantia nigra pars compacta (snpc) leading to motor deficits. 2020-04-06 2023-08-13 Not clear
Laís M Cabral, Thiago S Moreira, Ana C Takakura, Bárbara Falquett. Attenuated baroreflex in a Parkinson's disease animal model coincides with impaired activation of non-C1 neurons. Autonomic neuroscience : basic & clinical. vol 225. 2020-03-24. PMID:32092676. orthostatic hypotension is one of the most common symptoms observed in parkinson's disease (pd), a neurodegenerative disease caused by death of dopaminergic neurons in the substantia nigra pars compacta (snc), and it is associated with denervation of the heart and impairment of the baroreflex. 2020-03-24 2023-08-13 rat
Himadri Shekhaar Baul, Ceera Manikandan, Dwaipayan Se. Cannabinoid receptor as a potential therapeutic target for Parkinson's Disease. Brain research bulletin. vol 146. 2020-03-10. PMID:30664919. parkinson's disease (pd) is the second most prevalent neurodegenerative disease, characterized by the loss of dopaminergic neurons from substantia nigra pars compacta of basal ganglia caused due to gene mutation, misfolded protein aggregation, reactive oxygen species generation and inflammatory stress. 2020-03-10 2023-08-13 Not clear