| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tanishka S Saraf, Yiming Chen, Richa Tyagi, Clinton E Cana. Altered brain serotonin 5-HT Neuropharmacology. 2023-11-03. PMID:37923121. |
altered brain serotonin 5-ht there are no approved pharmacotherapies for fragile x syndrome (fxs), a monogenic, neurodevelopmental disorder typified by neuropsychiatric symptoms, including intellectual disability and auditory hypersensitivity. |
2023-11-03 |
2023-11-08 |
Not clear |
| Tanishka S Saraf, Ryan P McGlynn, Omkar M Bhatavdekar, Raymond G Booth, Clinton E Cana. FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT ACS chemical neuroscience. vol 13. issue 24. 2022-12-21. PMID:36473166. |
fpt, a 2-aminotetralin, is a potent serotonin 5-ht there are no approved medicines for fragile x syndrome (fxs), a monogenic, neurodevelopmental disorder. |
2022-12-21 |
2023-08-14 |
Not clear |
| Valeria Buzzelli, Emilia Carbone, Antonia Manduca, Sara Schiavi, Alessandro Feo, Julia V Perederiy, Kyle H Ambert, Marvin Hausman, Viviana Trezz. Psilocybin mitigates the cognitive deficits observed in a rat model of Fragile X syndrome. Psychopharmacology. 2022-12-05. PMID:36469097. |
as serotonin is involved in synaptic remodeling and maturation, serotonergic insufficiency during childhood may have a compounding effect on brain patterning in neurodevelopmental disorders, manifesting as behavioral and emotional symptoms. |
2022-12-05 |
2023-08-14 |
rat |
| Hongmei Dai, Yoshikazu Kitami, Yu-Ichi Goto, Masayuki Ito. 5-HT International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430502. |
5-ht rett syndrome (rtt) is an x-linked neurodevelopmental disorder caused by mutations in the gene that encodes methyl cpg-binding protein 2 (mecp2) and is characterized by the loss of acquired motor and language skills, stereotypic movements, respiratory abnormalities and autistic features. |
2022-11-26 |
2023-08-14 |
Not clear |
| Robert D Levitan, Maria Sqapi, Martin Post, Julia A Knight, Stephen J Lye, Stephen G Matthew. Increasing maternal age predicts placental protein expression critical for fetal serotonin metabolism: Potential implications for neurodevelopmental research. Placenta. vol 130. 2022-11-07. PMID:36343528. |
high fetal exposure to serotonin and increasing maternal age both contribute to the risk for neurodevelopmental disorders. |
2022-11-07 |
2023-08-14 |
Not clear |
| The people behind the papers - Roberto De Gregorio and Ji Sze. Development (Cambridge, England). vol 149. issue 21. 2022-10-31. PMID:36314568. |
serotonin uptake receptor (sert) plays an important role in neural circuit development and reduced sert function is associated with neurodevelopmental disorders. |
2022-10-31 |
2023-08-14 |
Not clear |
| Elena M Kondaurova, Irina I Belokopytova, Elisabeth A Kulikova, Nikita V Khotskin, Tatiana V Ilchibaeva, Anton S Tsybko, Nina K Popova, Vladimir S Naumenk. On the role of serotonin 5-HT Behavioural brain research. 2022-10-24. PMID:36280010. |
on the role of serotonin 5-ht autism spectrum disorders (asds) are some of the most common neurodevelopmental disorders; however, the mechanisms underlying asds are still poorly understood. |
2022-10-24 |
2023-08-14 |
Not clear |
| Christopher J O'Connell, Evan L Reeder, Sean M Collins, Kainat Lungani, Sophia V Norman, Matthew J Robso. Mild traumatic brain injury elicits time- and region-specific reductions in serotonin transporter protein expression and uptake capacity. Neuroreport. vol 33. issue 14. 2022-09-05. PMID:36062511. |
the monoamine neurotransmitter serotonin (5-ht) is important for the regulation of behavior, and aberrations in 5-ht signaling are linked to several neuropsychiatric and neurodevelopmental disorders. |
2022-09-05 |
2023-08-14 |
Not clear |
| Min-Jue Xie, Keiko Iwata, Yasuyuki Ishikawa, Yuki Nomura, Tomomi Tani, Koshi Murata, Yugo Fukazawa, Hideo Matsuzak. Autistic-Like Behavior and Impairment of Serotonin Transporter and AMPA Receptor Trafficking in Frontiers in genetics. vol 12. 2021-11-10. PMID:34745222. |
autistic-like behavior and impairment of serotonin transporter and ampa receptor trafficking in autism spectrum disorder (asd), characterized by profound impairment in social interactions and communication skills, is the most common neurodevelopmental disorder. |
2021-11-10 |
2023-08-13 |
Not clear |
| Toni S Pearson, Laura Gilbert, Thomas Opladen, Angeles Garcia-Cazorla, Mario Mastrangelo, Vincenzo Leuzzi, Stacy K H Tay, Jolanta Sykut-Cegielska, Roser Pons, Saadet Mercimek-Andrews, Mitsuhiro Kato, Thomas Lücke, Mari Oppebøen, Manju A Kurian, Dora Steel, Filippo Manti, Kathleen D Meeks, Kathrin Jeltsch, Lisa Flin. AADC deficiency from infancy to adulthood: Symptoms and developmental outcome in an international cohort of 63 patients. Journal of inherited metabolic disease. vol 43. issue 5. 2021-10-05. PMID:32369189. |
aromatic l-amino acid decarboxylase deficiency (aadcd) is a rare, autosomal recessive neurodevelopmental disorder characterized by impaired synthesis of dopamine, noradrenaline, adrenaline and serotonin, leading to a complex syndrome of motor, behavioral, and autonomic symptoms. |
2021-10-05 |
2023-08-13 |
human |
| Jennifer L Ames, Christine Ladd-Acosta, M Daniele Fallin, Yinge Qian, Laura A Schieve, Carolyn DiGuiseppi, Li-Ching Lee, Eric P Kasten, Guoli Zhou, Jennifer Pinto-Martin, Ellen M Howerton, Christopher L Eaton, Lisa A Croe. Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders. Biological psychiatry. vol 90. issue 4. 2021-08-10. PMID:34116791. |
maternal psychiatric conditions, treatment with selective serotonin reuptake inhibitors, and neurodevelopmental disorders. |
2021-08-10 |
2023-08-13 |
Not clear |
| Jennifer L Ames, Christine Ladd-Acosta, M Daniele Fallin, Yinge Qian, Laura A Schieve, Carolyn DiGuiseppi, Li-Ching Lee, Eric P Kasten, Guoli Zhou, Jennifer Pinto-Martin, Ellen M Howerton, Christopher L Eaton, Lisa A Croe. Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders. Biological psychiatry. vol 90. issue 4. 2021-08-10. PMID:34116791. |
this study aims to clarify relationships of maternal psychiatric conditions and selective serotonin reuptake inhibitor (ssri) use during preconception and pregnancy with risk of neurodevelopmental disorders in offspring. |
2021-08-10 |
2023-08-13 |
Not clear |
| Jieon Lee, Diana Avramets, Byungsun Jeon, Hyunah Cho. Modulation of Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor. Molecules (Basel, Switzerland). vol 26. issue 11. 2021-07-12. PMID:34199418. |
modulation of serotonin receptors in neurodevelopmental disorders: focus on 5-ht7 receptor. |
2021-07-12 |
2023-08-13 |
Not clear |
| Andrea Forero, Hsing-Ping Ku, Ana Belén Malpartida, Sina Wäldchen, Judit Alhama-Riba, Christina Kulka, Benjamin Aboagye, William H J Norton, Andrew M J Young, Yu-Qiang Ding, Robert Blum, Markus Sauer, Olga Rivero, Klaus-Peter Lesc. Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Neuropharmacology. vol 168. 2021-05-27. PMID:32113967. |
our findings further support the critical role of cdh13 in the development of dorsal raphe 5-ht circuitries, a mechanism that may underlie specific clinical features observed in neurodevelopmental disorders. |
2021-05-27 |
2023-08-13 |
mouse |
| Tingting Xi, Jinlin W. A Review on the Mechanism Between Different Factors and the Occurrence of Autism and ADHD. Psychology research and behavior management. vol 14. 2021-04-17. PMID:33859505. |
in addition, other neurotransmitter such as norepinephrine (ne) and serotonin (5-ht) signaling factors coming down to these two neurodevelopmental disorders and how their abnormal concentration present in the blood as well as the completely opposite results among experimental groups and control group will be elaborated. |
2021-04-17 |
2023-08-13 |
Not clear |
| Angel Carvajal-Oliveros, Jorge M Campusan. Studying the Contribution of Serotonin to Neurodevelopmental Disorders. Can This Fly? Frontiers in behavioral neuroscience. vol 14. 2021-01-30. PMID:33510625. |
studying the contribution of serotonin to neurodevelopmental disorders. |
2021-01-30 |
2023-08-13 |
Not clear |
| Gang-Bin Tang, Ting-Wei Mi, Man-Lian Sun, Ya-Jie Xu, Shu-Guang Yang, Hong-Zhen Du, Saijilafu, Zhao-Qian Teng, Jun Gao, Chang-Mei Li. Overexpression of serotonin receptor 5b expression rescues neuronal and behavioral deficits in a mouse model of Kabuki syndrome. IBRO reports. vol 9. 2020-09-28. PMID:32775759. |
5-hydroxytryptamine receptor 5b (5-ht5b) is a gene coding for a g protein-coupled receptor (gpcr) that plays key roles in several neurodevelopmental disorders. |
2020-09-28 |
2023-08-13 |
mouse |
| Rachel M Rahn, Susan E Maloney, Lindsey M Brier, Joseph D Dougherty, Joseph P Culve. Maternal Fluoxetine Exposure Alters Cortical Hemodynamic and Calcium Response of Offspring to Somatosensory Stimuli. eNeuro. vol 6. issue 6. 2020-09-07. PMID:31843753. |
epidemiological studies have found an increased incidence of neurodevelopmental disorders in populations prenatally exposed to selective serotonin reuptake inhibitors (ssris). |
2020-09-07 |
2023-08-13 |
mouse |
| Marta Pratelli, Massimo Pasqualett. Serotonergic neurotransmission manipulation for the understanding of brain development and function: Learning from Tph2 genetic models. Biochimie. vol 161. 2019-07-08. PMID:30513372. |
in addition, cumulating evidences have linked alteration in 5-ht neurotransmission with the onset of psychiatric and neurodevelopmental disorders, such as depression, autisms and schizophrenia. |
2019-07-08 |
2023-08-13 |
human |
| Susan E Maloney, Shyam Akula, Michael A Rieger, Katherine B McCullough, Krystal Chandler, Adrian M Corbett, Audrey E McGowin, Joseph D Doughert. Examining the Reversibility of Long-Term Behavioral Disruptions in Progeny of Maternal SSRI Exposure. eNeuro. vol 5. issue 4. 2019-02-27. PMID:30073191. |
serotonin plays widespread trophic roles during neurodevelopment; thus perturbations to this system during development may increase risk for neurodevelopmental disorders. |
2019-02-27 |
2023-08-13 |
Not clear |