All Relations between Optic Nerve Injuries and retinal ganglion neuron

Publication Sentence Publish Date Extraction Date Species
Xuan Xiao, Tantai Zhao, Kiyoharu J Miyagishima, Shan Chen, Wei Li, Francisco M Nadal-Nicolá. Establishing the ground squirrel as a superb model for retinal ganglion cell disorders and optic neuropathies. Laboratory investigation; a journal of technical methods and pathology. vol 101. issue 9. 2021-08-27. PMID:34253851. retinal ganglion cell (rgc) death occurs after optic nerve injury due to acute trauma or chronic degenerative conditions such as optic neuropathies (e.g., glaucoma). 2021-08-27 2023-08-13 mouse
Seyedeh-Zahra Seyedrazizadeh, Sara Poosti, Abdoreza Nazari, Mehdi Alikhani, Faezeh Shekari, Farzad Pakdel, Koorosh Shahpasand, Leila Satarian, Hossein Baharvan. Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury. Stem cell research & therapy. vol 11. issue 1. 2021-06-18. PMID:32460894. retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (rgc) degeneration. 2021-06-18 2023-08-13 human
Liu Yun-Jia, Chen Xi, Zhang Jie-Qiong, Zhu Jing-Yi, Lin Sen, Ye Jia. Semaphorin3A increases M1-like microglia and retinal ganglion cell apoptosis after optic nerve injury. Cell & bioscience. vol 11. issue 1. 2021-05-30. PMID:34039431. semaphorin3a increases m1-like microglia and retinal ganglion cell apoptosis after optic nerve injury. 2021-05-30 2023-08-13 Not clear
Liu Yun-Jia, Chen Xi, Zhang Jie-Qiong, Zhu Jing-Yi, Lin Sen, Ye Jia. Semaphorin3A increases M1-like microglia and retinal ganglion cell apoptosis after optic nerve injury. Cell & bioscience. vol 11. issue 1. 2021-05-30. PMID:34039431. the mechanisms leading to retinal ganglion cell (rgc) death after optic nerve injury have not been fully elucidated. 2021-05-30 2023-08-13 Not clear
Yuan-Yuan He, Lu Wang, Tao Zhang, Shi-Jun Weng, Jian Lu, Yong-Mei Zhon. Aerobic exercise delays retinal ganglion cell death after optic nerve injury. Experimental eye research. vol 200. 2021-03-02. PMID:32919994. aerobic exercise delays retinal ganglion cell death after optic nerve injury. 2021-03-02 2023-08-13 rat
Anna Wójcik-Gryciuk, Olga Gajewska-Woźniak, Katarzyna Kordecka, Paweł M Boguszewski, Wioletta Waleszczyk, Małgorzata Sku. Neuroprotection of Retinal Ganglion Cells with AAV2-BDNF Pretreatment Restoring Normal TrkB Receptor Protein Levels in Glaucoma. International journal of molecular sciences. vol 21. issue 17. 2021-02-23. PMID:32872441. intravitreal delivery of brain-derived neurotrophic factor (bdnf) by injection of recombinant protein or by gene therapy can alleviate retinal ganglion cell (rgc) loss after optic nerve injury (oni) or laser-induced ocular hypertension (oht). 2021-02-23 2023-08-13 Not clear
Xin Xia, Caroline Y Yu, Minjuan Bian, Catalina B Sun, Bogdan Tanasa, Kun-Che Chang, Dawn M Bruffett, Hrishikesh Thakur, Sahil H Shah, Cara Knasel, Evan G Cameron, Michael S Kapiloff, Jeffrey L Goldber. MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury. PloS one. vol 15. issue 12. 2021-01-18. PMID:33315889. mef2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury. 2021-01-18 2023-08-13 mouse
Gabriel Nascimento-Dos-Santos, Leandro Coelho Teixeira-Pinheiro, Almir Jordão da Silva-Júnior, Luiza Rachel Pinheiro de Carvalho, Louise Alessandra Mesentier-Louro, William W Hauswirth, Rosalia Mendez-Otero, Marcelo Felippe Santiago, Hilda Petrs-Silv. Effects of a combinatorial treatment with gene and cell therapy on retinal ganglion cell survival and axonal outgrowth after optic nerve injury. Gene therapy. vol 27. issue 1-2. 2021-01-06. PMID:31243393. effects of a combinatorial treatment with gene and cell therapy on retinal ganglion cell survival and axonal outgrowth after optic nerve injury. 2021-01-06 2023-08-13 human
Gabriel Nascimento-Dos-Santos, Leandro Coelho Teixeira-Pinheiro, Almir Jordão da Silva-Júnior, Luiza Rachel Pinheiro de Carvalho, Louise Alessandra Mesentier-Louro, William W Hauswirth, Rosalia Mendez-Otero, Marcelo Felippe Santiago, Hilda Petrs-Silv. Effects of a combinatorial treatment with gene and cell therapy on retinal ganglion cell survival and axonal outgrowth after optic nerve injury. Gene therapy. vol 27. issue 1-2. 2021-01-06. PMID:31243393. in the present work, we evaluated the neuroprotective and neuroregenerative potential of pigment epithelium-derived factor (pedf) gene therapy alone and combined with human mesenchymal stem cell (hmsc) therapy after optic nerve injury by analysis of retinal ganglion cell survival and axonal outgrowth. 2021-01-06 2023-08-13 human
Euido Nishijima, Kazuhiko Namekata, Atsuko Kimura, Xiaoli Guo, Chikako Harada, Takahiko Noro, Tadashi Nakano, Takayuki Harad. Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury. Scientific reports. vol 10. issue 1. 2020-12-18. PMID:32973242. optic nerve injury induces optic nerve degeneration and retinal ganglion cell (rgc) death that lead to visual disturbance. 2020-12-18 2023-08-13 mouse
Y Hua Wang, D Wu Wang, Z Qin Yi. Synergistic protection of RGCs by olfactory ensheathing cells and alpha-crystallin through regulation of the Akt/BAD Pathway. Journal francais d'ophtalmologie. vol 43. issue 8. 2020-11-03. PMID:32631692. our recent in vivo studies have shown that olfactory ensheathing cells (oecs) and α-crystallin can promote retinal ganglion cell (rgc) survival and axonal regeneration synergistically after optic nerve injury. 2020-11-03 2023-08-13 Not clear
Jia-Xing Zhou, Yun-Jia Liu, Xi Chen, Xi Zhang, Jie Xu, Ke Yang, Dong Wang, Sen Lin, Jian Y. Low-Intensity Pulsed Ultrasound Protects Retinal Ganglion Cell From Optic Nerve Injury Induced Apoptosis via Yes Associated Protein. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:29950973. low-intensity pulsed ultrasound protects retinal ganglion cell from optic nerve injury induced apoptosis via yes associated protein. 2020-09-29 2023-08-13 Not clear
Bei Liu, Yu-Jia Li. Carvedilol Promotes Retinal Ganglion Cell Survival Following Optic Nerve Injury via ASK1-p38 MAPK Pathway. CNS & neurological disorders drug targets. vol 18. issue 9. 2020-09-24. PMID:31577210. carvedilol promotes retinal ganglion cell survival following optic nerve injury via ask1-p38 mapk pathway. 2020-09-24 2023-08-13 Not clear
L Martínez-Alcantar, D K Talavera-Carrillo, J U Pineda-Salazar, M Ávalos-Viveros, G Gutiérrez-Ospina, B V Phillips-Farfán, A L Fuentes-Farías, E Meléndez-Herrer. Anterior chamber associated immune deviation to cytosolic neural antigens avoids self-reactivity after optic nerve injury and polarizes the retinal environment to an anti-inflammatory profile. Journal of neuroimmunology. vol 333. 2020-03-23. PMID:31112803. this work evaluated the effect of acaid induced to three neural tissue-derived extracts (whole extract, cytosolic extract, ce; or organelle-membrane extract) prior to optic nerve injury on retinal ganglion cell (rgc) survival. 2020-03-23 2023-08-13 Not clear
Andrew Osborne, Tasneem Z Khatib, Lalana Songra, Amanda C Barber, Katie Hall, George Y X Kong, Peter S Widdowson, Keith R Marti. Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor/tropomyosin-related kinase receptor-B signaling. Cell death & disease. vol 9. issue 10. 2019-11-13. PMID:30258047. previous studies have demonstrated that intravitreal delivery of brain-derived neurotrophic factor (bdnf) by injection of recombinant protein or by gene therapy can alleviate retinal ganglion cell (rgc) loss after optic nerve injury. 2019-11-13 2023-08-13 mouse
Jeffrey M Harder, Pete A Williams, Ileana Soto, Nicole E Foxworth, Kimberly A Fernandes, Nelson F Freeburg, Richard T Libby, Simon W M Joh. Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice. Cell death & disease. vol 9. issue 6. 2019-11-05. PMID:29899326. jnk2 and jnk3 have been shown to promote retinal ganglion cell (rgc) death after optic nerve injury. 2019-11-05 2023-08-13 mouse
Yuriko Azuchi, Kazuhiko Namekata, Tadayuki Shimada, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Atsuko Saito, Kanato Yamagata, Takayuki Harad. Role of neuritin in retinal ganglion cell death in adult mice following optic nerve injury. Scientific reports. vol 8. issue 1. 2019-10-16. PMID:29973613. role of neuritin in retinal ganglion cell death in adult mice following optic nerve injury. 2019-10-16 2023-08-13 mouse
Heather M Schmitt, Cassandra L Schlamp, Robert W Nickell. Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. vol 34. issue 3. 2019-10-01. PMID:29211617. targeting hdac3 activity with rgfp966 protects against retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury. 2019-10-01 2023-08-13 Not clear
Fang-Yu Liu, Guang-Wu Li, Chang-Hua Sun, Sha Chen, Jun-Fei Cao, Qian-Qian Ma, Sheng-Yun Fan. Effects of bone marrow mesenchymal stem cells transfected with Ang-1 gene on hyperoxia-induced optic nerve injury in neonatal mice. Journal of cellular physiology. vol 233. issue 11. 2019-09-25. PMID:29377123. optic nerve injury triggered retinal ganglion cell (rgc) death and optic nerve atrophy lead to visual loss. 2019-09-25 2023-08-13 mouse
Louise A Mesentier-Louro, Pamela Rosso, Valentina Carito, Rosalia Mendez-Otero, Marcelo F Santiago, Paolo Rama, Alessandro Lambiase, Paola Tirass. Nerve Growth Factor Role on Retinal Ganglion Cell Survival and Axon Regrowth: Effects of Ocular Administration in Experimental Model of Optic Nerve Injury. Molecular neurobiology. vol 56. issue 2. 2019-07-11. PMID:29869196. nerve growth factor role on retinal ganglion cell survival and axon regrowth: effects of ocular administration in experimental model of optic nerve injury. 2019-07-11 2023-08-13 human