| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Katom. [Inhibition of stress-responsive signaling pathway prevents neural cell death following optic nerve injury]. Nippon Ganka Gakkai zasshi. vol 118. issue 11. 2015-03-03. PMID:25543382. |
optic nerve injury (oni) induces retinal ganglion cell (rgc) death and optic nerve atrophy that lead to visual loss. |
2015-03-03 |
2023-08-13 |
mouse |
| Hani Levkovitch-Verbin, Daria Makarovsky, Shelly Vande. Comparison between axonal and retinal ganglion cell gene expression in various optic nerve injuries including glaucoma. Molecular vision. vol 19. 2014-07-21. PMID:24357921. |
comparison between axonal and retinal ganglion cell gene expression in various optic nerve injuries including glaucoma. |
2014-07-21 |
2023-08-12 |
Not clear |
| Thomas V Johnson, Nicholas W DeKorver, Victoria A Levasseur, Andrew Osborne, Alessia Tassoni, Barbara Lorber, Janosch P Heller, Rafael Villasmil, Natalie D Bull, Keith R Martin, Stanislav I Tomare. Identification of retinal ganglion cell neuroprotection conferred by platelet-derived growth factor through analysis of the mesenchymal stem cell secretome. Brain : a journal of neurology. vol 137. issue Pt 2. 2014-04-11. PMID:24176979. |
intravitreal transplantation of mesenchymal stem cells slows retinal ganglion cell death in models of optic nerve injury, but the mechanism of action remains unclear. |
2014-04-11 |
2023-08-12 |
human |
| Nan Wu, Jia Yu, Shaojun Chen, Jiangning Xu, Xi Ying, Mao Ye, Yiru Li, Yi Wan. α-Crystallin protects RGC survival and inhibits microglial activation after optic nerve crush. Life sciences. vol 94. issue 1. 2014-02-20. PMID:24220677. |
activation of retinal microglial cells (rmcs) is known to contribute to retinal ganglion cell (rgc) death after optic nerve injury. |
2014-02-20 |
2023-08-12 |
rat |
| Heike Diekmann, Marco Leibinger, Dietmar Fische. Do growth-stimulated retinal ganglion cell axons find their central targets after optic nerve injury? New insights by three-dimensional imaging of the visual pathway. Experimental neurology. vol 248. 2013-11-27. PMID:23816572. |
do growth-stimulated retinal ganglion cell axons find their central targets after optic nerve injury? |
2013-11-27 |
2023-08-12 |
mouse |
| Patrick Yu-Wai-Man, Philip G Griffith. Steroids for traumatic optic neuropathy. The Cochrane database of systematic reviews. issue 6. 2013-11-19. PMID:23771729. |
following the initial injury, optic nerve swelling within the optic nerve canal can result in secondary retinal ganglion cell loss. |
2013-11-19 |
2023-08-12 |
Not clear |
| T Katome, K Namekata, X Guo, K Semba, D Kittaka, K Kawamura, A Kimura, C Harada, H Ichijo, Y Mitamura, T Harad. Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury. Cell death and differentiation. vol 20. issue 2. 2013-06-21. PMID:22976835. |
optic nerve injury (oni) induces retinal ganglion cell (rgc) death and optic nerve atrophy that lead to visual loss. |
2013-06-21 |
2023-08-12 |
mouse |
| Panida Chindasub, James D Lindsey, Karen Duong-Polk, Christopher K Leung, Robert N Weinre. Inhibition of histone deacetylases 1 and 3 protects injured retinal ganglion cells. Investigative ophthalmology & visual science. vol 54. issue 1. 2013-03-05. PMID:23197683. |
optic nerve injury triggers reduction of thy-1 promoter activation followed by retinal ganglion cell (rgc) death. |
2013-03-05 |
2023-08-12 |
Not clear |
| Xu Wang, Ying Li, Yan He, Hong-Sheng Liang, En-Zhong Li. A novel animal model of partial optic nerve transection established using an optic nerve quantitative amputator. PloS one. vol 7. issue 9. 2013-01-28. PMID:22973439. |
research into retinal ganglion cell (rgc) degeneration and neuroprotection after optic nerve injury has received considerable attention and the establishment of simple and effective animal models is of critical importance for future progress. |
2013-01-28 |
2023-08-12 |
Not clear |
| Masayoshi Nakatani, Yuko Shinohara, Miki Takii, Hisato Mori, Nobuharu Asai, Shigeru Nishimura, Yoko Furukawa-Hibi, Yoshiaki Miyamoto, Atsumi Nitt. Periocular injection of in situ hydrogels containing Leu-Ile, an inducer for neurotrophic factors, promotes retinal ganglion cell survival after optic nerve injury. Experimental eye research. vol 93. issue 6. 2012-01-17. PMID:22001716. |
periocular injection of in situ hydrogels containing leu-ile, an inducer for neurotrophic factors, promotes retinal ganglion cell survival after optic nerve injury. |
2012-01-17 |
2023-08-12 |
rat |
| C Galindo-Romero, M Avilés-Trigueros, M Jiménez-López, F J Valiente-Soriano, M Salinas-Navarro, F Nadal-Nicolás, M P Villegas-Pérez, M Vidal-Sanz, M Agudo-Barrius. Axotomy-induced retinal ganglion cell death in adult mice: quantitative and topographic time course analyses. Experimental eye research. vol 92. issue 5. 2011-07-14. PMID:21354138. |
the fate of retinal ganglion cells after optic nerve injury has been thoroughly described in rat, but not in mice, despite the fact that this species is amply used as a model to study different experimental paradigms that affect retinal ganglion cell population. |
2011-07-14 |
2023-08-12 |
mouse |
| Patrick Yu-Wai-Man, Philip G Griffith. Steroids for traumatic optic neuropathy. The Cochrane database of systematic reviews. issue 1. 2011-02-28. PMID:21249673. |
following the initial injury, optic nerve swelling within the optic nerve canal can result in secondary retinal ganglion cell loss. |
2011-02-28 |
2023-08-12 |
Not clear |
| Akiyasu Kanamori, Maria-Magdalena Catrinescu, Noriko Kanamori, Katrina A Mears, Rachel Beaubien, Leonard A Levi. Superoxide is an associated signal for apoptosis in axonal injury. Brain : a journal of neurology. vol 133. issue 9. 2010-09-20. PMID:20495185. |
together, these results are consistent with superoxide being an upstream signal for retinal ganglion cell apoptosis after optic nerve injury. |
2010-09-20 |
2023-08-12 |
rat |
| Jian-Min Luo, Yi-Qun Geng, Ye Zhi, Ming-Zhi Zhang, Nico van Rooijen, Qi Cu. Increased intrinsic neuronal vulnerability and decreased beneficial reaction of macrophages on axonal regeneration in aged rats. Neurobiology of aging. vol 31. issue 6. 2010-07-13. PMID:18755527. |
previously we showed that macrophage activation in the eye by intravitreal application of zymosan increased retinal ganglion cell (rgc) survival and axonal regeneration after optic nerve injury. |
2010-07-13 |
2023-08-12 |
rat |
| Yoshiki Koriyama, Mamoru Ohno, Takahiro Kimura, Satoru Kat. Neuroprotective effects of 5-S-GAD against oxidative stress-induced apoptosis in RGC-5 cells. Brain research. vol 1296. 2009-12-29. PMID:19686711. |
in a previous paper, we reported a novel neuroprotective action of 5-s-gad on rat retinal ganglion cell apoptosis induced by optic nerve injury and intraocular n-methyl-d-aspartate treatment in vivo. |
2009-12-29 |
2023-08-12 |
rat |
| Ryosuke Kashimoto, Takuji Kurimoto, Tomomitsu Miyoshi, Norio Okamoto, Yuichi Tagami, Shinichirou Oono, Yoshimasa Ito, Osamu Mimur. Cilostazol promotes survival of axotomized retinal ganglion cells in adult rats. Neuroscience letters. vol 436. issue 2. 2008-08-13. PMID:18395344. |
optic nerve injury leads to retinal ganglion cell (rgc) death possibly from a deprivation of neurotrophic factors and/or the down-regulation of intracellular camp. |
2008-08-13 |
2023-08-12 |
rat |
| Yasunari Munemasa, Yasushi Kitaoka, Yasuhiro Hayashi, Hiroyuki Takeda, Hiromi Fujino, Ritsuko Ohtani-Kaneko, Kazuaki Hirata, Satoki Uen. Effects of unoprostone on phosphorylated extracellular signal-regulated kinase expression in endothelin-1-induced retinal and optic nerve damage. Visual neuroscience. vol 25. issue 2. 2008-05-19. PMID:18442442. |
we investigated the effects of unoprostone on extracellular signal-regulated kinase (erk) in et-1-induced retinal ganglion cell (rgc) death and optic nerve injury. |
2008-05-19 |
2023-08-12 |
Not clear |
| P Yu-Wai-Man, P G Griffith. Steroids for traumatic optic neuropathy. The Cochrane database of systematic reviews. issue 4. 2008-01-17. PMID:17943877. |
following the initial injury, optic nerve swelling within the optic nerve canal can result in secondary retinal ganglion cell loss. |
2008-01-17 |
2023-08-12 |
Not clear |
| Sarah A Dunlop, Lisa B G Tee, Michel A L Goossens, R Victoria Stirling, Livia Hool, Jenny Rodger, L D Beazle. Regenerating optic axons restore topography after incomplete optic nerve injury. The Journal of comparative neurology. vol 505. issue 1. 2008-01-09. PMID:17729282. |
following complete optic nerve injury in a lizard, ctenophorus ornatus, retinal ganglion cell (rgc) axons regenerate but fail to restore retinotectal topography unless animals are trained on a visual task (beazley et al. |
2008-01-09 |
2023-08-12 |
Not clear |
| Li-quan Lü, Yi-cheng L. [Myelin associated inhibitors and regeneration of optic nerve]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. vol 42. issue 9. 2007-03-20. PMID:17173755. |
blocking the inhibitors and their receptors or changing the intrinsic state of the neuron to overcome the inhibition may promote retinal ganglion cell axonal regeneration after optic nerve injury, which bring a hope to solve the problem of repair of injured optic nerve. |
2007-03-20 |
2023-08-12 |
Not clear |