All Relations between Sleep Apnea Syndromes and hmgcr

Publication Sentence Publish Date Extraction Date Species
Wei Tan, Xiujuan Deng, Xiaoning Tan, Guangbo Ta. Assessing the effects of HMGCR, LPL, and PCSK9 inhibition on sleep apnea: Mendelian randomization analysis of drug targets. Medicine. vol 103. issue 43. 2024-10-29. PMID:39470521. according to our dmr analysis, hmgcr and pcsk9, which act by lowering serum ldl-c levels, were inversely associated with the risk of sleep apnea syndrome (or = 0.627; 95% ci = 0.511-0.767; p = 6.30e-06) (or = 0.775; 95% ci = 0.677-0.888; p = .0002). 2024-10-29 2024-10-31 Not clear
Wei Tan, Xiujuan Deng, Xiaoning Tan, Guangbo Ta. Assessing the effects of HMGCR, LPL, and PCSK9 inhibition on sleep apnea: Mendelian randomization analysis of drug targets. Medicine. vol 103. issue 43. 2024-10-29. PMID:39470521. the dmr results suggested that the use of hmgcr lipid-lowering drugs (such as statins) and pcsk9 inhibitors has a protective effect against sleep apnea syndrome. 2024-10-29 2024-10-31 Not clear