All Relations between Sleep Apnea Syndromes and hmgcr
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Wei Tan, Xiujuan Deng, Xiaoning Tan, Guangbo Ta. Assessing the effects of HMGCR, LPL, and PCSK9 inhibition on sleep apnea: Mendelian randomization analysis of drug targets. Medicine. vol 103. issue 43. 2024-10-29. PMID:39470521. |
according to our dmr analysis, hmgcr and pcsk9, which act by lowering serum ldl-c levels, were inversely associated with the risk of sleep apnea syndrome (or = 0.627; 95% ci = 0.511-0.767; p = 6.30e-06) (or = 0.775; 95% ci = 0.677-0.888; p = .0002). |
2024-10-29 |
2024-10-31 |
Not clear |
Wei Tan, Xiujuan Deng, Xiaoning Tan, Guangbo Ta. Assessing the effects of HMGCR, LPL, and PCSK9 inhibition on sleep apnea: Mendelian randomization analysis of drug targets. Medicine. vol 103. issue 43. 2024-10-29. PMID:39470521. |
the dmr results suggested that the use of hmgcr lipid-lowering drugs (such as statins) and pcsk9 inhibitors has a protective effect against sleep apnea syndrome. |
2024-10-29 |
2024-10-31 |
Not clear |