| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.) vol 165 issue 2023 36869551 |
in hypothalamus and hippocampus, clock (bmal1 and clock) and tight junction (ocln and tjp2) genes were improved by prebiotics, and corticotropin-releasing hormone receptor genes, crf1 and crf2, were also significantly regulated for mitigation of depression and anxiety caused by sleep deprivation. |
2023-03-04 |
2023-03-06 |
mouse |
| Shuang Hu, Xuan Liu, Yuefan Wang, Rong Zhang, Shougang We. Melatonin protects against body weight gain induced by sleep deprivation in mice. Physiology & behavior vol issue 2022 36183851 |
meanwhile, the transcription factor ppar\xce\xb3 protein in liver increased, but there were no significant changes in hepatic circadian proteins bmal1 and rev-erb\xce\xb1 after 10 consecutive days of sleep deprivation. |
2022-10-02 |
2023-01-30 |
mouse |
| Peiyuan Qiu, Jian Jiang, Zhen Liu, Yijun Cai, Tao Huang, Yan Wang, Qiming Liu, Yanhong Nie, Fang Liu, Jiumu Cheng, Qing Li, Yun-Chi Tang, Mu-Ming Poo, Qiang Sun, Hung-Chun Chan. BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders. National science review vol 6 issue 1 2021 34691834 |
ablation of bmal1 up-regulated transcriptional programs toward inflammatory and stress responses, with transcription networks associated with human sleep deprivation, major depressive disorders, and aging. |
2021-10-26 |
2023-01-26 |
human |
| Chad Smith, Kyle J Trageser, Henry Wu, Francis J Herman, Umar Haris Iqbal, Maria Sebastian-Valverde, Tal Frolinger, Emma Zeng, Giulio Maria Pasinett. Anxiolytic effects of NLRP3 inflammasome inhibition in a model of chronic sleep deprivation. Translational psychiatry vol 11 issue 1 2021 33446652 |
the study further showed sleep deprivation alters the expression of the circadian gene bmal1, which critically regulated nlrp3 expression and il-1\xce\xb2 production. |
2021-06-18 |
2023-01-26 |
mouse |
| Jiabao Hou, Qianni Shen, Xing Wan, Bo Zhao, Yang Wu, Zhongyuan Xi. REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. Behavioural brain research vol 364 issue 2020 30779975 |
western blot analysis revealed that sleep deprivation inhibited hippocampal bmal1 and egr1 expression for more than 7 days after sevoflurane inhalation. |
2020-03-09 |
2023-01-26 |
rat |
| Beilin Zhang, Yanxia Gao, Yang Li, Jing Yang, Hua Zha. Sleep Deprivation Influences Circadian Gene Expression in the Lateral Habenula. Behavioural neurology vol 2016 issue 2017 27413249 |
and then the changes of clock gene expression (per1, per2, and bmal1) in the lhb after 6 hours of sleep deprivation were detected by using real-time quantitative pcr (qpcr). |
2017-03-01 |
2023-01-25 |
rat |
| Katrin Ackermann, Rosina Plomp, Oscar Lao, Benita Middleton, Victoria L Revell, Debra J Skene, Manfred Kayse. Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans. Chronobiology international vol 30 issue 7 2014 23738906 |
during one night of total sleep deprivation, bmal1 expression was suppressed, the heat shock gene hspa1b expression was induced, and the amplitude of the melatonin rhythm increased, whereas other high-amplitude clock gene rhythms (e.g., per1-3, rev-erb\xce\xb1) remained unaffected. |
2014-02-03 |
2023-01-25 |
human |
| Val\\xc3\\xa9rie Mongrain, Francesco La Spada, Thomas Curie, Paul Franke. Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex. PloS one vol 6 issue 10 2012 22039518 |
here, we investigate a possible mechanism by which sleep deprivation (sd) could alter clock gene expression by quantifying dna-binding of the core-clock transcription factors clock, npas2, and bmal1 to the cis-regulatory sequences of target clock genes in mice. |
2012-02-28 |
2023-01-25 |
mouse |