All Relations between Spinocerebellar Ataxias and cerebellum purkinje cell

Reference Sentence Publish Date Extraction Date Species
Hui Ho Vanessa Chang, Anna A Cook, Alanna J Watt, Kathleen E Culle. Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6). Cells vol 11 issue 17 2022 36078147 loss of flocculus purkinje cell firing precision leads to impaired gaze stabilization in a mouse model of spinocerebellar ataxia type 6 (sca6). 2022-09-09 2022-09-14 Not clear
Sharan R Srinivasan, Haoran Huang, Wei-Chih Chang, Joshua A Nasburg, Hai M Nguyen, Tim Strassmaier, Heike Wulff, Vikram G Shakkotta. Discovery of novel activators of large-conductance calcium-activated potassium channels for the treatment of cerebellar ataxia. Molecular pharmacology vol issue 2022 35489717 impaired cerebellar purkinje neuron firing resulting from reduced expression of large-conductance calcium-activated potassium (bk) channels is a consistent feature in models of inherited neurodegenerative spinocerebellar ataxia (sca). 2022-04-30 2022-05-03 Not clear
Joshua J White, Laurens W J Bosman, Francois G C Blot, Catarina Os\\xc3\\xb3rio, Bram W Kuppens, Wilhelmina H J J Krijnen, Charlotte Andriessen, Chris I De Zeeuw, Dick Jaarsma, Martijn Schonewill. Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1. Brain pathology (Zurich, Switzerland) vol 31 issue 5 2021 33724582 region-specific preservation of purkinje cell morphology and motor behavior in the atxn1[82q] mouse model of spinocerebellar ataxia 1. 2022-02-03 2022-01-13 Not clear
Hanako Aoki, Miwa Higashi, Michi Okita, Noboru Ando, Shigeo Murayama, Kinya Ishikawa, Takanori Yokot. Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA) Cerebellum (London, England) vol issue 2022 35084690 thymidine kinase 2 and mitochondrial protein cox i in the cerebellum of patients with spinocerebellar ataxia type 31 caused by penta-nucleotide repeats (ttcca) spinocerebellar ataxia type 31 (sca31), an autosomal-dominant neurodegenerative disorder characterized by progressive cerebellar ataxia with purkinje cell degeneration, is caused by a heterozygous 2.5-3.8 kilobase penta-nucleotide repeat of (ttcca) 2022-01-27 2022-02-06 Not clear
David D Bushart, Annie J Zalon, Hongjiu Zhang, Logan M Morrison, Yuanfang Guan, Henry L Paulson, Vikram G Shakkottai, Hayley S McLoughli. Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3. Cerebellum (London, England) vol 20 issue 1 2021 32789747 antisense oligonucleotide therapy targeted against atxn3 improves potassium channel-mediated purkinje neuron dysfunction in spinocerebellar ataxia type 3. 2021-10-25 2022-01-13 Not clear
Joshua J White, Laurens W J Bosman, Francois G C Blot, Catarina Os\\xc3\\xb3rio, Bram W Kuppens, Wilhelmina H J J Krijnen, Charlotte Andriessen, Chris I De Zeeuw, Dick Jaarsma, Martijn Schonewill. Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1. Brain pathology (Zurich, Switzerland) vol 31 issue 5 2021 33724582 region-specific preservation of purkinje cell morphology and motor behavior in the atxn1[82q] mouse model of spinocerebellar ataxia 1. 2021-10-13 2022-01-13 Not clear
Ravi Chopra, David D Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang, Hillary P Handler, Luke J Man, Warunee Dansithong, Daniel R Scoles, Stefan M Pulst, Harry T Orr, Vikram G Shakkotta. Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1. Human molecular genetics vol 29 issue 19 2021 32964235 altered capicua expression drives regional purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1. 2021-08-30 2022-01-13 Not clear
Ravi Chopra, David D Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang, Hillary P Handler, Luke J Man, Warunee Dansithong, Daniel R Scoles, Stefan M Pulst, Harry T Orr, Vikram G Shakkotta. Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1. Human molecular genetics vol 29 issue 19 2021 32964235 using the atxn1[82q] model of spinocerebellar ataxia type 1 (sca1), we explored the hypothesis that regional differences in purkinje neuron degeneration could provide novel insights into selective vulnerability. 2021-08-30 2022-01-13 Not clear
Chia-Wei Lin, Chia-Hao Fan, Ya-Chin Chang, Hsiu Mei Hsieh-L. ERK activation precedes Purkinje cell loss in mice with Spinocerebellar ataxia type 17. Neuroscience letters vol 738 issue 2021 32877710 erk activation precedes purkinje cell loss in mice with spinocerebellar ataxia type 17. 2021-04-30 2022-01-13 Not clear
Kazuhiko Namikawa, Alessandro Dorigo, Marta Zagrebelsky, Giulio Russo, Toni Kirmann, Wieland Fahr, Stefan D\\xc3\\xbcbel, Martin Korte, Reinhard W K\\xc3\\xb6ste. Modeling Neurodegenerative Spinocerebellar Ataxia Type 13 in Zebrafish Using a Purkinje Neuron Specific Tunable Coexpression System. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 39 issue 20 2020 30862666 modeling neurodegenerative spinocerebellar ataxia type 13 in zebrafish using a purkinje neuron specific tunable coexpression system. 2020-06-15 2022-01-13 Not clear
Rogier van der Stijl, Sebo Withoff, Dineke S Verbee. Corrigendum to \"Spinocerebellar ataxia: miRNAs expose biological pathways underlying pervasive Purkinje cell degeneration\" [Neurobiol. Dis. 2017 Dec 108 148-158]. Neurobiology of disease vol 116 issue 2019 29198496 corrigendum to "spinocerebellar ataxia: mirnas expose biological pathways underlying pervasive purkinje cell degeneration" [neurobiol. 2019-11-20 2022-01-13 Not clear
David D Bushart, Ravi Chopra, Vikrant Singh, Geoffrey G Murphy, Heike Wulff, Vikram G Shakkotta. Targeting potassium channels to treat cerebellar ataxia. Annals of clinical and translational neurology vol 5 issue 3 2019 29560375 in a mouse model of spinocerebellar ataxia type 1 (sca1), reduced potassium channel function contributes to altered membrane excitability resulting in impaired purkinje neuron spiking. 2019-11-20 2022-01-13 Not clear
Michela Ripolone, Valeria Lucchini, Dario Ronchi, Gigliola Fagiolari, Andreina Bordoni, Francesco Fortunato, Stefania Mondello, Sara Bonato, Mirella Meregalli, Yvan Torrente, Stefania Corti, Giacomo P Comi, Maurizio Moggio, Monica Sciacc. Purkinje cell COX deficiency and mtDNA depletion in an animal model of spinocerebellar ataxia type 1. Journal of neuroscience research vol 96 issue 9 2019 30113722 purkinje cell cox deficiency and mtdna depletion in an animal model of spinocerebellar ataxia type 1. 2019-11-11 2022-01-13 Not clear
Jakub Trzesniewski, Sandrine Altmann, Levy J\\xc3\\xa4ger, Josef P Kapfhamme. Reduced Purkinje cell size is compatible with near normal morphology and function of the cerebellar cortex in a mouse model of spinocerebellar ataxia. Experimental neurology vol 311 issue 2019 30312605 reduced purkinje cell size is compatible with near normal morphology and function of the cerebellar cortex in a mouse model of spinocerebellar ataxia. 2019-04-10 2022-01-13 Not clear
Miaozhen Huang, Dineke S Verbee. Why do so many genetic insults lead to Purkinje Cell degeneration and spinocerebellar ataxia? Neuroscience letters vol 688 issue 2019 29421540 why do so many genetic insults lead to purkinje cell degeneration and spinocerebellar ataxia? 2019-02-18 2022-01-13 Not clear
Miaozhen Huang, Dineke S Verbee. Why do so many genetic insults lead to Purkinje Cell degeneration and spinocerebellar ataxia? Neuroscience letters vol 688 issue 2019 29421540 the main question that remains yet unsolved is why do some many genetic insults lead to purkinje cell degeneration and spinocerebellar ataxia? 2019-02-18 2022-01-13 Not clear
Miaozhen Huang, Dineke S Verbee. Why do so many genetic insults lead to Purkinje Cell degeneration and spinocerebellar ataxia? Neuroscience letters vol 688 issue 2019 29421540 in this review, we discuss the current consensus on shared mechanisms underlying the pervasive purkinje cell loss in spinocerebellar ataxia. 2019-02-18 2022-01-13 Not clear
Rogier van der Stijl, Sebo Withoff, Dineke S Verbee. Spinocerebellar ataxia: miRNAs expose biological pathways underlying pervasive Purkinje cell degeneration. Neurobiology of disease vol 108 issue 2018 28823930 spinocerebellar ataxia: mirnas expose biological pathways underlying pervasive purkinje cell degeneration. 2018-07-23 2022-01-13 Not clear
James M Dell'Orco, Stefan M Pulst, Vikram G Shakkotta. Potassium channel dysfunction underlies Purkinje neuron spiking abnormalities in spinocerebellar ataxia type 2. Human molecular genetics vol 26 issue 20 2018 29016852 potassium channel dysfunction underlies purkinje neuron spiking abnormalities in spinocerebellar ataxia type 2. 2018-03-05 2022-01-13 Not clear
James M Dell'Orco, Stefan M Pulst, Vikram G Shakkotta. Potassium channel dysfunction underlies Purkinje neuron spiking abnormalities in spinocerebellar ataxia type 2. Human molecular genetics vol 26 issue 20 2018 29016852 in a mouse model of spinocerebellar ataxia type 2 (sca2), a progressive reduction in purkinje neuron firing frequency accompanies cell atrophy. 2018-03-05 2022-01-13 Not clear
Page: 
1   2   3