| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ella Borgenheimer, Katherine Hamel, Carrie Sheeler, Francisco Labrada Moncada, Kaelin Sbrocco, Ying Zhang, Marija Cvetanovi. Single nuclei RNA sequencing investigation of the Purkinje cell and glial changes in the cerebellum of transgenic Spinocerebellar ataxia type 1 mice. Frontiers in cellular neuroscience. vol 16. 2022-12-02. PMID:36457352. |
single nuclei rna sequencing investigation of the purkinje cell and glial changes in the cerebellum of transgenic spinocerebellar ataxia type 1 mice. |
2022-12-02 |
2023-08-14 |
mouse |
| Ella Borgenheimer, Katherine Hamel, Carrie Sheeler, Francisco Labrada Moncada, Kaelin Sbrocco, Ying Zhang, Marija Cvetanovi. Single nuclei RNA sequencing investigation of the Purkinje cell and glial changes in the cerebellum of transgenic Spinocerebellar ataxia type 1 mice. Frontiers in cellular neuroscience. vol 16. 2022-12-02. PMID:36457352. |
spinocerebellar ataxia type 1 (sca1) is a progressive neurodegenerative disease characterized by a severe degeneration of cerebellar purkinje cells (pcs) and cerebellar gliosis. |
2022-12-02 |
2023-08-14 |
mouse |
| Robin Cabeza-Ruiz, Luis Velázquez-Pérez, Roberto Pérez-Rodríguez, Kathrin Reet. ConvNets for automatic detection of polyglutamine SCAs from brain MRIs: state of the art applications. Medical & biological engineering & computing. 2022-11-17. PMID:36385616. |
polyglutamine spinocerebellar ataxias (polyq scas) are a group of neurodegenerative diseases, clinically and genetically heterogeneous, characterized by loss of balance and motor coordination due to dysfunction of the cerebellum and its connections. |
2022-11-17 |
2023-08-14 |
Not clear |
| Catarina Osório, Joshua J White, Heiling Lu, Gerrit C Beekhof, Francesca Romana Fiocchi, Charlotte A Andriessen, Stephanie Dijkhuizen, Laura Post, Martijn Schonewill. Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1. Brain : a journal of neurology. 2022-11-10. PMID:36352508. |
spinocerebellar ataxias are neurodegenerative diseases the hallmark symptom of which is the development of ataxia due to cerebellar dysfunction. |
2022-11-10 |
2023-08-14 |
mouse |
| Catarina Osório, Joshua J White, Heiling Lu, Gerrit C Beekhof, Francesca Romana Fiocchi, Charlotte A Andriessen, Stephanie Dijkhuizen, Laura Post, Martijn Schonewill. Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1. Brain : a journal of neurology. 2022-11-10. PMID:36352508. |
together, our results suggest that abnormal synaptic signalling and intrinsic plasticity during the pre-ataxia stage of spinocerebellar ataxias underlie an aberrant cerebellar circuitry that anticipates the full extent of the disease severity. |
2022-11-10 |
2023-08-14 |
mouse |
| Kavyashree Kulamarva, Umesh Chikkanna, Kishore Kumar Ramakrishna, Hemant Bhargav, Selva Ganapathy Velayutham, Shivarama Varamball. Integrative Approach Improves Fall Risk and Postural Stability in Spinocerebellar Ataxia-2 - A Case Report. International journal of yoga. vol 15. issue 2. 2022-11-04. PMID:36329776. |
spinocerebellar ataxias (scas) comprise a large heterogeneous group of autosomal dominant cerebellar ataxias. |
2022-11-04 |
2023-08-14 |
Not clear |
| Jing Guo, Zhouyu Jiang, Xinyuan Liu, Haoru Li, Bharat B Biswal, Bo Zhou, Wei Sheng, Qing Gao, Hui Chen, Yunshuang Fan, Wenyan Zhu, Jian Wang, Huafu Chen, Chen Li. Cerebello-cerebral resting-state functional connectivity in spinocerebellar ataxia type 3. Human brain mapping. 2022-10-17. PMID:36250694. |
spinocerebellar ataxia type 3 (sca3) is a neurodegenerative disorder characterized by progressive motor and nonmotor deficits concomitant with degenerative pathophysiological changes within the cerebellum. |
2022-10-17 |
2023-08-14 |
Not clear |
| Tatsuaki Kurosaki, Tetsuo Ashizaw. The genetic and molecular features of the intronic pentanucleotide repeat expansion in spinocerebellar ataxia type 10. Frontiers in genetics. vol 13. 2022-10-06. PMID:36199580. |
spinocerebellar ataxia type 10 (sca10) is characterized by progressive cerebellar neurodegeneration and, in many patients, epilepsy. |
2022-10-06 |
2023-08-14 |
Not clear |
| Libera Siciliano, Giusy Olivito, Nicole Urbini, Maria Caterina Silveri, Maria Leggi. " Biomedicines. vol 10. issue 9. 2022-09-23. PMID:36140267. |
accordingly, this study aims to investigate whether motor reserve (mr), likely to be boosted by exercise engagement in a lifetime, affects motor symptom severity, cognitive functioning, and functional brain networks in spinocerebellar ataxia type 2 (sca2)-a cerebellar neurodegenerative disease. |
2022-09-23 |
2023-08-14 |
Not clear |
| Shigeki Hirano, Atsuhiko Sugiyama, Kimihito Ara. Noradrenergic Pathway to the Cerebellum: the Study Must Go On. Cerebellum (London, England). 2022-09-23. PMID:36149525. |
cerebellar dysfunction and noradrenergic system may relate to tremor in parkinson disease and essential tremor, motor learning, and the vestibulo-ocular reflex in spinocerebellar ataxias. |
2022-09-23 |
2023-08-14 |
rat |
| Ashley M Paul, Weiyi Mu, Ankur Butala, Kemar E Gree. Pearls & Oy-sters: Deep Phenotyping of Abnormal Eye Movements Advances the Detection of Gerstmann-Sträussler-Scheinker Syndrome. Neurology. 2022-09-20. PMID:36127142. |
she was initially postulated to have spinocerebellar ataxia or atypical parkinsonism with cerebellar features. |
2022-09-20 |
2023-08-14 |
Not clear |
| Anna A Cook, Sriram Jayabal, Jacky Sheng, Eviatar Fields, Tsz Chui Sophia Leung, Sabrina Quilez, Eileen McNicholas, Lois Lau, Shixia Huang, Alanna J Wat. Activation of TrkB-Akt signaling rescues deficits in a mouse model of SCA6. Science advances. vol 8. issue 37. 2022-09-16. PMID:36112675. |
spinocerebellar ataxia type 6 (sca6) is a neurodegenerative disease resulting in motor coordination deficits and cerebellar pathology. |
2022-09-16 |
2023-08-14 |
mouse |
| Satoshi Zeniya, Nobuo Sanjo, Hiroya Kuwahara, Kinya Ishikawa, Miwa Higashi, Akiko Matsunaga, Makoto Yoneda, Hidehiro Mizusawa, Takanori Yokot. Spinocerebellar Ataxia Type 31 Exacerbated by Anti-amino Terminal of Alpha-enolase Autoantibodies. Internal medicine (Tokyo, Japan). vol 61. issue 18. 2022-09-14. PMID:36104177. |
this is the first report of cerebellar ataxia associated with genetic spinocerebellar ataxia with concomitant cerebellar type he. |
2022-09-14 |
2023-08-14 |
Not clear |
| Pallavi Asthana, Gajendra Kumar, Lukasz M Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K Wszolek, Chi Him Eddie M. Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression. NPJ Regenerative medicine. vol 7. issue 1. 2022-09-06. PMID:36064798. |
finally, we found a correlative decrease in human gria1 mrna expression in the cerebellum of patients with ataxia-telangiectasia and spinocerebellar ataxia type 6 patient ipsc-derived purkinje cells, pointing to the clinical relevance of glutamatergic system. |
2022-09-06 |
2023-08-14 |
mouse |
| Szilvia E Mezey, Josef P Kapfhammer, Etsuko Shimobayash. Transcriptome Profile of a New Mouse Model of Spinocerebellar Ataxia Type 14 Implies Changes in Cerebellar Development. Genes. vol 13. issue 8. 2022-08-26. PMID:36011327. |
transcriptome profile of a new mouse model of spinocerebellar ataxia type 14 implies changes in cerebellar development. |
2022-08-26 |
2023-08-14 |
mouse |
| Szilvia E Mezey, Josef P Kapfhammer, Etsuko Shimobayash. Transcriptome Profile of a New Mouse Model of Spinocerebellar Ataxia Type 14 Implies Changes in Cerebellar Development. Genes. vol 13. issue 8. 2022-08-26. PMID:36011327. |
the autosomal dominant inherited spinocerebellar ataxias (scas) are a group of neurodegenerative disorders characterized by cerebellar atrophy and loss of purkinje neurons. |
2022-08-26 |
2023-08-14 |
mouse |
| Qin-Wei Wu, Josef P Kapfhamme. The Emerging Key Role of the mGluR1-PKCγ Signaling Pathway in the Pathogenesis of Spinocerebellar Ataxias: A Neurodevelopmental Viewpoint. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012439. |
spinocerebellar ataxias (scas) are a heterogeneous group of autosomal dominantly inherited progressive disorders with degeneration and dysfunction of the cerebellum. |
2022-08-26 |
2023-08-14 |
Not clear |
| Kimberly Luttik, Leon Tejwani, Hyoungseok Ju, Terri Driessen, Cleo J L M Smeets, Chandrakanth Reddy Edamakanti, Aryaan Khan, Joy Yun, Puneet Opal, Janghoo Li. Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 34. 2022-08-15. PMID:35969780. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including purkinje cells (pcs) in the cerebellum. |
2022-08-15 |
2023-08-14 |
mouse |
| Ilaria Balbo, Francesca Montarolo, Federica Genovese, Filippo Tempia, Eriola Hoxh. Effects of the administration of Elovl5-dependent fatty acids on a spino-cerebellar ataxia 38 mouse model. Behavioral and brain functions : BBF. vol 18. issue 1. 2022-08-06. PMID:35933444. |
spinocerebellar ataxia 38 (sca38) is a rare autosomal neurological disorder characterized by ataxia and cerebellar atrophy. |
2022-08-06 |
2023-08-14 |
mouse |
| Victor Olmos, Neha Gogia, Kimberly Luttik, Fatema Haidery, Janghoo Li. The extra-cerebellar effects of spinocerebellar ataxia type 1 (SCA1): looking beyond the cerebellum. Cellular and molecular life sciences : CMLS. vol 79. issue 8. 2022-07-08. PMID:35802260. |
the extra-cerebellar effects of spinocerebellar ataxia type 1 (sca1): looking beyond the cerebellum. |
2022-07-08 |
2023-08-14 |
mouse |