| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seyed Reza Mousavi, Amir Hooshang Mohammadpour, Mohammad Moshiri, Javad Feizy, Atena Pourtaji, Sara Samad. A pilot study of neuroprotective effect of granulocyte colony-stimulating factor (G-CSF) in patients with carbon monoxide poisoning: a double-blind, randomized, placebo-controlled trial. Naunyn-Schmiedeberg's archives of pharmacology. 2023-01-30. PMID:36715735. |
the primary endpoint was brain ischemia improvement based on ct findings and the secondary endpoints examined improvements in the modified rankin scale (mrs), national institutes of health stroke scale (nihss), and barthel index as well as s-100β concentrations. |
2023-01-30 |
2023-08-14 |
rat |
| Jui-Sheng Chen, Hao-Kuang Wang, Chien-Yu Hsu, Yu-Ting Su, Jia-Shing Chen, Cheng-Loong Liang, Patrick Ching-Ho Hsieh, Cheng-Chun Wu, Aij-Lie Kwa. HDAC1 deregulation promotes neuronal loss and deficit of motor function in stroke pathogenesis. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:34381129. |
therefore, we investigated the role of hdac1 in stroke by using a rat model of endothelin-1-induced brain ischemia. |
2021-11-12 |
2023-08-13 |
rat |
| Violeta Durán-Laforet, Carolina Peña-Martínez, Alicia García-Culebras, María Isabel Cuartero, Eng H Lo, María Ángeles Moro, Ignacio Lizasoai. Role of TLR4 in Neutrophil Dynamics and Functions: Contribution to Stroke Pathophysiology. Frontiers in immunology. vol 12. 2021-11-10. PMID:34745132. |
it is known that tlr4 is implicated in brain damage and inflammation after stroke and that tlr4 absence induces neutrophil reprogramming toward a protective phenotype in brain ischemia, but the mechanisms remain unknown. |
2021-11-10 |
2023-08-13 |
Not clear |
| Valeria Valsecchi, Giusy Laudati, Ornella Cuomo, Rossana Sirabella, Lucio Annunziato, Giuseppe Pignatar. The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke. Cell death & disease. vol 12. issue 5. 2021-10-05. PMID:33931586. |
overall, mtf-dependent activation of ncx1 and their upregulation elicited by rlip, besides unraveling a new molecular pathway of neuroprotection during brain ischemia, might represent an additional mechanism to intervene in stroke pathophysiology. |
2021-10-05 |
2023-08-13 |
rat |
| Anna Koopman, Frank-Erik de Leeuw, Frederick Meije. CT perfusion hypervolemia: brain ischemia or stroke mimic? Neuroradiology. vol 61. issue 4. 2019-07-23. PMID:30719544. |
ct perfusion hypervolemia: brain ischemia or stroke mimic? |
2019-07-23 |
2023-08-13 |
Not clear |
| Sung-Min Cho, Abhishek Deshpande, Vinay Pasupuleti, Adrian V Hernandez, Ken Uchin. Radiographic and symptomatic brain ischemia in CEA and CAS: A systematic review and meta-analysis. Neurology. vol 89. issue 19. 2017-11-13. PMID:29021357. |
in a systematic review, we compared ratio of new periprocedural radiographic brain ischemia (rbi) to the number of strokes and tias among patients undergoing carotid endarterectomy (cea) and carotid artery stenting (cas). |
2017-11-13 |
2023-08-13 |
Not clear |
| Yvonne Schwammenthal, Rakefet Tsabari, David Orion, Oleg Merzlyak, Salo Haratz, Shlomi Peretz, Natan M Bornstein, Gal Ifergane, Michal Einhorn, Ehud Schwammenthal, Diklah Geva, David Tann. Shifting Perceptions of Risk and Reward: Use of Anticoagulation in Patients With Acute Brain Ischemia and Atrial Fibrillation: Nine-Year Data From a National Acute Stroke Registry (National Acute Stroke Israeli Survey [NASIS]). Stroke. vol 48. issue 4. 2017-06-05. PMID:28258255. |
shifting perceptions of risk and reward: use of anticoagulation in patients with acute brain ischemia and atrial fibrillation: nine-year data from a national acute stroke registry (national acute stroke israeli survey [nasis]). |
2017-06-05 |
2023-08-13 |
Not clear |
| Guo-qian He, Wen-ming Xu, Jin-fang Li, Shuai-shuai Li, Bin Liu, Xiao-dan Tan, Chang-qing L. Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells. Molecular brain. vol 8. 2016-09-26. PMID:26698301. |
brain ischemia induces the expression of gadd45b, which stimulates recovery after stroke and may play a protective role in cerebral ischemia. |
2016-09-26 |
2023-08-13 |
rat |
| Odysseus Zis, Si Zhang, Katerina Dorovini-Zis, Lijuan Wang, Weihong Son. Hypoxia signaling regulates macrophage migration inhibitory factor (MIF) expression in stroke. Molecular neurobiology. vol 51. issue 1. 2015-10-20. PMID:24826917. |
to determine whether the expression of mif in the human brain is altered following ischemia, brain sections from 10 stroke patients were examined with an antibody against mif. |
2015-10-20 |
2023-08-13 |
human |
| Angela M Brennan-Minnella, Seok Joon Won, Raymond A Swanso. NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke. Antioxidants & redox signaling. vol 22. issue 2. 2015-09-14. PMID:24628477. |
neuronal superoxide production contributes to cell death in both glutamate excitotoxicity and brain ischemia (stroke). |
2015-09-14 |
2023-08-12 |
Not clear |
| Patricia B de la Tremblaye, Julie Raymond, Marc R Milot, Zul Merali, Hélène Plamondo. Evidence of lasting dysregulation of neuroendocrine and HPA axis function following global cerebral ischemia in male rats and the effect of Antalarmin on plasma corticosterone level. Hormones and behavior. vol 65. issue 3. 2014-12-23. PMID:24444675. |
these findings support persistent neuroendocrine dysfunctions following brain ischemia likely to contribute to emotional and cognitive impairments observed in survivors of cardiac arrest and stroke. |
2014-12-23 |
2023-08-12 |
rat |
| Valérie Petegnief, Anna M Plana. SIRT1 regulation modulates stroke outcome. Translational stroke research. vol 4. issue 6. 2014-09-15. PMID:24323420. |
its role in acute nervous system injury, such as brain ischemia, is emerging, but whether sirt1 activation improves stroke outcome is still a matter of controversy. |
2014-09-15 |
2023-08-12 |
human |
| Valérie Petegnief, Anna M Plana. SIRT1 regulation modulates stroke outcome. Translational stroke research. vol 4. issue 6. 2014-09-15. PMID:24323420. |
in the present review, we will document present knowledge about the contribution of sirt1 in death/survival in cell and animal models of brain ischemia and discuss whether sirt1 could be a valuable target for therapeutic intervention in human stroke. |
2014-09-15 |
2023-08-12 |
human |
| Thanh G Phan, Andrew Demchuk, Velandai Srikanth, Brian Silver, Suresh C Patel, Philip A Barber, Steven R Levine, Michael D Hil. Proof of concept study: relating infarct location to stroke disability in the NINDS rt-PA trial. Cerebrovascular diseases (Basel, Switzerland). vol 35. issue 6. 2014-03-27. PMID:23838753. |
the summed alberta stroke program early ct score (aspects) for noncontrast head ct scan represents the extent of early brain ischemia and has been shown to be useful for predicting stroke outcome. |
2014-03-27 |
2023-08-12 |
Not clear |
| Dustin J Hines, Philip G Haydo. Inhibition of a SNARE-sensitive pathway in astrocytes attenuates damage following stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 10. 2013-04-26. PMID:23467341. |
a strong body of research has defined the role of excitotoxic glutamate in animal models of brain ischemia and stroke; however, clinical trials of glutamate receptor antagonists have demonstrated their limited capacity to prevent brain damage following ischemia. |
2013-04-26 |
2023-08-12 |
mouse |
| Katrina Foo, Laura Blumenthal, Heng-Ye Ma. Regulation of neuronal bioenergy homeostasis by glutamate. Neurochemistry international. vol 61. issue 3. 2013-01-22. PMID:22709672. |
most of the energy cost is attributable to the glutamatergic system; under pathological conditions such as stroke and brain ischemia, neural energy depletion is accompanied by a massive release of glutamate. |
2013-01-22 |
2023-08-12 |
Not clear |
| Zheng Ke, Shea Ping Yip, Le Li, Xiao-Xiang Zheng, Kai-Yu Ton. The effects of voluntary, involuntary, and forced exercises on brain-derived neurotrophic factor and motor function recovery: a rat brain ischemia model. PloS one. vol 6. issue 2. 2012-04-02. PMID:21347437. |
stroke rehabilitation with different exercise paradigms has been investigated, but which one is more effective in facilitating motor recovery and up-regulating brain neurotrophic factor (bdnf) after brain ischemia would be interesting to clinicians and patients. |
2012-04-02 |
2023-08-12 |
rat |
| Shuang-Shuang Dai, Yuan-Guo Zho. Adenosine 2A receptor: a crucial neuromodulator with bidirectional effect in neuroinflammation and brain injury. Reviews in the neurosciences. vol 22. issue 2. 2011-08-23. PMID:21476942. |
this review summarizes recent developments that have contributed to our understanding of how adenosine 2a receptors (a2ars) modulate brain damage in various animal models of acute neurological injuries, including brain ischemia, traumatic brain injury, spinal cord injury and hemorrhage stroke. |
2011-08-23 |
2023-08-12 |
Not clear |
| Anna Morancho, Anna Rosell, Lidia García-Bonilla, Joan Montane. Metalloproteinase and stroke infarct size: role for anti-inflammatory treatment? Annals of the New York Academy of Sciences. vol 1207. 2010-11-09. PMID:20955435. |
synthesized mmp inhibitors and several compounds used for stroke secondary prevention, such as anti-inflammatory drugs, might decrease mmps and improve the acute treatment of human brain ischemia without compromising the beneficial effects of matrix plasticity during stroke recovery. |
2010-11-09 |
2023-08-12 |
human |
| A-S Knoepfli, L Sekoranja, C Bonvin, J Delavelle, Z Kulcsar, D Rüfenacht, H Yilmaz, R Sztajzel, S Altrichter, K-O Lövbla. Evaluation of perfusion CT and TIBI grade in acute stroke for predicting thrombolysis benefit and clinical outcome. Journal of neuroradiology = Journal de neuroradiologie. vol 36. issue 3. 2009-10-08. PMID:19062093. |
to evaluate the prognostic accuracy of combining perfusion ct (pct) and thrombolysis in brain ischemia (tibi) ultrasonographic grade in the triage of stroke patients who will benefit from thrombolysis and in predicting the clinical outcome. |
2009-10-08 |
2023-08-12 |
Not clear |