| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tianqi Liu, Tianshu Yang, Zhe Xu, Siran Tan, Tingru Pan, Na Wan, Shu L. MicroRNA-193b-3p regulates hepatocyte apoptosis in selenium-deficient broilers by targeting MAML1. Journal of inorganic biochemistry. vol 186. 2019-05-16. PMID:29990747. |
we tested the apoptosis of se-deficient broiler livers and microrna-193b-transfected primary hepatocytes using qpcr, western blot (wb) and flow cytometry. |
2019-05-16 |
2023-08-13 |
Not clear |
| Jing Xu, Jian He, Huang He, Renjun Peng, Jian X. TWEAK-Fn14 Influences Neurogenesis Status via Modulating NF-κB in Mice with Spinal Cord Injury. Molecular neurobiology. vol 54. issue 9. 2019-05-08. PMID:27822714. |
apoptosis status in the injured area was examined via tdt-mediated dutp-biotin nick end-labeling (tunel) staining, the expression of gap-43 in injured spinal cord was quantified by immunohistochemistry and expressions of tweak, fn14, nf-κb, tnf-α, and il-1β were evaluated by either western blot or elisa. |
2019-05-08 |
2023-08-13 |
mouse |
| Ya-Nan Song, Ding Yuan, Chang-Cheng Zhang, Luo-Pei Wang, Yu-Min He, Ting Wang, Zhi-Yong Zho. [Effect of saponins extracted from Panax japonicus on inhibiting cardiomyocyte apoptosis by AMPK/Sirt1/NF-κB signaling pathway in aging rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 23. 2019-05-08. PMID:29376267. |
their myocardial morphology changes were observed by using haematoxylin-eoin(he) staining; cardiomyocyte apoptosis was tested by using tunel assays; and the protein expression levels of bcl-2, bax, il-1β, tnf-α, ampk, p-ampk, sirt1, and ac-nf-κb p65 in myocardial tissues of rats were detected by western blot. |
2019-05-08 |
2023-08-13 |
rat |
| Haibin Yan, Bingyun Zhang, Chongbin Fang, Liqiu Che. miR-340 alleviates chemoresistance of osteosarcoma cells by targeting ZEB1. Anti-cancer drugs. vol 29. issue 5. 2019-05-08. PMID:29494357. |
plasmid construction and transfection, mirna arrays, pcr analyses, and western blot analysis, as well as mtt, apoptosis, and luciferase assays were carried out in mg-63 cells and mg-63/cisplatin (ddp)-resistant cells. |
2019-05-08 |
2023-08-13 |
Not clear |
| Yan Wang, Hui Wang, Hui Ge, Zhuo Yan. AG-1031 induced autophagic cell death and apoptosis in C6 glioma cells associated with Notch-1 signaling pathway. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575026. |
results from hoechst 33342 staining and western blot assay indicated that ag-1031 induced c6 cell apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Rahyza I F Assis, Malgorzata Wiench, Karina G Silvério, Rodrigo A da Silva, Geórgia da Silva Feltran, Enilson A Sallum, Marcio Z Casati, Francisco H Nociti, Denise C Andi. RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation. PloS one. vol 13. issue 12. 2019-05-06. PMID:30507955. |
hbmscs were treated with complete culture medium, 50 μm rg108 and dmso for three days and subjected to viability and apoptosis assays, global and gene-specific methylation/hydroxymethylation, transcript levels' analysis of epigenetic machinery enzymes and multipotency markers, protein activities of dnmts and tets, immunofluorescence staining and western blot analysis for nanog and oct4 and flow cytometry for cd105. |
2019-05-06 |
2023-08-13 |
human |
| Dong Wang, Liang Tang, Huihui Wu, Kai Wang, Dongyun G. MiR-127-3p inhibits cell growth and invasiveness by targeting ITGA6 in human osteosarcoma. IUBMB life. vol 70. issue 5. 2019-05-03. PMID:29573114. |
the expression of apoptosis and migration related were also detected by western blot. |
2019-05-03 |
2023-08-13 |
human |
| Xiaoxiao Gao, Li Han, Nan Ding, Yu Mu, Peipei Guan, Caijuan Hu, Xueshi Huan. Bafilomycin C1 induces G0/G1 cell-cycle arrest and mitochondrial-mediated apoptosis in human hepatocellular cancer SMMC7721 cells. The Journal of antibiotics. vol 71. issue 9. 2019-05-03. PMID:29752478. |
cell-cycle arrest and induced apoptosis in tumor tissues in a mouse model treated with bafilomycin c1 were demonstrated by histological analyses, western blot and tunel. |
2019-05-03 |
2023-08-13 |
mouse |
| Jindao Wu, Xiongxiong Pan, Heling Fu, Yuan Zheng, Youjin Dai, Yuan Yin, Qin Chen, Qingting Hao, Dan Bao, Daorong Ho. Effect of curcumin on glycerol-induced acute kidney injury in rats. Scientific reports. vol 7. issue 1. 2019-05-01. PMID:28860665. |
finally, cell apoptosis in renal tissue was detected using in situ tunel apoptosis fluorescence staining and expression of proteins associated with apoptotic, oxidative stress and lipid oxidative related signaling pathways were detected using immunohistochemical staining and western blot. |
2019-05-01 |
2023-08-13 |
rat |
| C Wang, Z P Mao, L Wang, F H Zhang, G H Wu, D Y Wang, J L Sh. Cordycepin inhibits cell growth and induces apoptosis in human cholangiocarcinoma. Neoplasma. vol 64. issue 6. 2019-04-29. PMID:28895407. |
in the present study, colony formation assay, cell-counting kit-8 (cck-8) assay and tumor xenograft experiment were performed to evaluate the effect of cordycepin on human cca cell growth in vitro and in vivo; flow cytometric analysis was performed to evaluate the effect of cordycepin on cell apoptosis; quantitative real-time reverse transcription pcr (qrt-pcr) and western blot assays were performed to evaluate the expression levels of caspase-3, bcl-2 and bax. |
2019-04-29 |
2023-08-13 |
human |
| C Wang, Z P Mao, L Wang, F H Zhang, G H Wu, D Y Wang, J L Sh. Cordycepin inhibits cell growth and induces apoptosis in human cholangiocarcinoma. Neoplasma. vol 64. issue 6. 2019-04-29. PMID:28895407. |
furthermore, the flow cytometric analysis, qrt-pcr and western blot assays showed that cordycepin could trigger qbc939 and rbe cells apoptosis by regulating the expression levels of caspase-3, bcl-2 and bax. |
2019-04-29 |
2023-08-13 |
human |
| Wen-Ying Wei, Zhen-Guo Ma, Ning Zhang, Si-Chi Xu, Yu-Pei Yuan, Xiao-Feng Zeng, Qi-Zhu Tan. Overexpression of CTRP3 protects against sepsis-induced myocardial dysfunction in mice. Molecular and cellular endocrinology. vol 476. 2019-04-29. PMID:29655602. |
additionally, ctrp3 suppressed cardiac apoptosis induced by lps in mice as indicated by terminal deoxynucleotidyl transferase nick-end labeling (tunel) staining and western blot for cleaved-caspase3, bax and bcl-2. |
2019-04-29 |
2023-08-13 |
mouse |
| Lulu Liu, Yun Huang, Xiangling Feng, Jihua Chen, Yanying Dua. Overexpressed Hsp70 alleviated formaldehyde-induced apoptosis partly via PI3K/Akt signaling pathway in human bronchial epithelial cells. Environmental toxicology. vol 34. issue 4. 2019-04-22. PMID:30600586. |
apoptosis and the expression levels of pi3k, akt, p-akt, mek, p-mek, and gli2 were detected by annexin-apc/7aad double-labeled flow cytometry and western blot. |
2019-04-22 |
2023-08-13 |
human |
| Yuqian Wang, Hong Zhao, Dezhou Wang, Miao Hao, Chenfei Kong, Xiaoming Zhao, Yiyao Gao, Jing Li, Baocai Liu, Bai Yang, Hao Zhang, Jinlan Jian. Inhibition of Autophagy Promoted Apoptosis and Suppressed Growth of Hepatocellular Carcinoma Upon Photothermal Exposure. Journal of biomedical nanotechnology. vol 15. issue 4. 2019-04-22. PMID:30841973. |
apoptosis was evaluated based on flow cytometry, western blot analysis of apoptosis related proteins (bax, bcl2, caspase 3), hoechst staining, and tunel staining. |
2019-04-22 |
2023-08-13 |
Not clear |
| Jing-Kui Wu, Qiao Yang, Yang-Yang Li, Dong-Jie Xi. [Effect of leech on VSMCs in early atherosclerosis rats via p38MAPK signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 16. 2019-04-19. PMID:29171240. |
immunological histological chemistry (ihc) was taken to measure the expression levels of proliferating cell nucleus antigen(pcna) and cell apoptosis proteinase-3(caspase-3), while the protein expression levels of mkk3, p38 and c-myc were detected by western blot. |
2019-04-19 |
2023-08-13 |
rat |
| Zhiyu He, Haoyu Tang, Xinru You, Keqing Huang, Arvind Dhinakar, Yang Kang, Qiaoli Yu, Jun W. BAPTA-AM Nanoparticle for the Curing of Acute Kidney Injury Induced by Ischemia/Reperfusion. Journal of biomedical nanotechnology. vol 14. issue 5. 2019-04-19. PMID:29883558. |
the assays of histological examination, elisa, immunohistochemistry, western blot, tunel and rt-pcr were utilized for the detection of apoptosis. |
2019-04-19 |
2023-08-13 |
rat |
| Hong Yao, Feijie Xu, Guangyu Wang, Shaowen Xie, Wenlong Li, Hequan Yao, Cong Ma, Zheying Zhu, Jinyi Xu, Shengtao X. Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors. European journal of medicinal chemistry. vol 167. 2019-04-18. PMID:30784881. |
flow cytometry and western blot analyses confirmed that compound 21c caused apoptosis of mcf-7 cells. |
2019-04-18 |
2023-08-13 |
human |
| Ya-Wei Li, Wei Zhang, Na Xu, Yan Li, Hong Zhang, Shi-Jie Lv, Wen-He Zh. [Dihydroartemisinin inhibits proliferation of pancreatic cancer JF-305 cells by regulating expression of apoptosis related proteins and production of reactive oxygen species]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 15. 2019-04-16. PMID:29139274. |
western blot was used to detect the protein expression changes of bax, bcl-2, cleaved caspase-3, cleaved caspase-9 and cyto c. as compared with the control group, the jf-305 cells proliferation was inhibited significantly(p<0.05) after treatment with different concentrations of dihydroartemisimin for 48 h; cell cycle was blocked in the g2/m phase; apoptotic morphology of nuclear condensation, aggregation, and fragmentation was found, and the apoptosis ratio was increased(p<0.05). |
2019-04-16 |
2023-08-13 |
human |
| Weijie Liang, Taibing Fan, Lin Liu, Lianzhong Zhan. Knockdown of growth-arrest specific transcript 5 restores oxidized low-density lipoprotein-induced impaired autophagy flux via upregulating miR-26a in human endothelial cells. European journal of pharmacology. vol 843. 2019-04-15. PMID:30468731. |
the effects of ox-ldl, gas5 or combined with mir-26a on apoptosis and autophagy were evaluated by flow cytometry analysis and western blot, respectively. |
2019-04-15 |
2023-08-13 |
human |
| Jinxin Wang, Ruilin Li, Zhiyuan Deng, Zuoyan Sun, Lijuan Chai, Hong Guo, Hong Wang, Lu Chen, Limin Hu, Shaoxia Wan. Xueshuantong for Injection Ameliorates Diabetic Nephropathy in a Rat Model of Streptozotocin-Induced Diabetes. The Chinese journal of physiology. vol 61. issue 6. 2019-04-15. PMID:30580505. |
apoptosis related factors such as cleaved caspase-3, bcl-2, bax and inflammationrelated factors, including tumor necrosis factor-α (tnf-α), interleukin 6 (il-6), il-1β, induciblenitric oxide synthase (inos) and intercellular adhesion molecule-1 (icam-1) were detected by pcror western blot. |
2019-04-15 |
2023-08-13 |
rat |