All Relations between apoptosis and hsp27

Publication Sentence Publish Date Extraction Date Species
Jeong Man Cho, Sojung Sun, Eunji Im, Hyunwon Yang, Tag Keun Yo. Triple Silencing of HSP27, cFLIP, and CLU Genes Promotes the Sensitivity of Doxazosin-Induced Apoptosis in PC-3 Prostate Cancer Cells. Medicines (Basel, Switzerland). vol 11. issue 3. 2024-03-27. PMID:38535120. triple silencing of hsp27, cflip, and clu genes promotes the sensitivity of doxazosin-induced apoptosis in pc-3 prostate cancer cells. 2024-03-27 2024-03-29 Not clear
Ismail Koyuncu, Ebru Temiz, Eray Metin Güler, Mustafa Durgun, Ozgür Yuksekdag, Simone Giovannuzzi, Claudiu T Supura. Effective Anticancer Potential of a New Sulfonamide as a Carbonic Anhydrase IX Inhibitor Against Aggressive Tumors. ChemMedChem. 2024-02-27. PMID:38323458. the expression of pro-apoptotic regulatory proteins (bad, bax, bid, bim, cyt-c, fas, fasl, tnf-a, tnf-r1, htra, smac, casp-3, -8, p21, p27, and p53) was increased, while the expression of anti-apoptotic proteins, apoptosis inhibitor proteins (iaps), and heat shock proteins (hsps) (bcl-2, bcl-w, ciap-2, hsp27, hsp60, hsp70, survivin, livin, and xiap) was decreased. 2024-02-27 2024-03-01 Not clear
Hugo Borges Dos Reis, Minos Esperândio Carvalho, Rafael Espigolan, Mirele Daiana Poleti, Dewison Ricardo Ambrizi, Mariana Piatto Berton, José Bento Sterman Ferraz, Elisângela Chicaroni de Mattos Oliveira, Joanir Pereira Ele. Genome-Wide Association (GWAS) Applied to Carcass and Meat Traits of Nellore Cattle. Metabolites. vol 14. issue 1. 2024-01-26. PMID:38276296. enrichment analyses showed the following significant terms (fdr ≤ 0.05) associated with the characteristics under study: for the rea, heat stress disorders and life cycle stages; for sft, insulin and nonesterified fatty acids; for sf7, apoptosis and heat shock proteins (hsp27); and for imf, metalloproteinase 2. 2024-01-26 2024-01-28 cattle
Xiaowen Bi, Miao Zhang, Jinyi Zhou, Xintong Yan, Lixia Cheng, Lan Luo, Chunhong Huang, Zhimin Yi. Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc. Cellular signalling. 2023-10-05. PMID:37797796. we found that overexpression of hsp27 in mcf-7 breast cancer cells reversed dna damage induced by adriamycin, and thereby reduced subsequent cell apoptosis. 2023-10-05 2023-10-07 Not clear
Weichen Hong, Yuhao Liu, Jiatian Liang, Chunyu Jiang, Meijin Yu, Wei Sun, Bin Huang, Na Dong, Lu Kang, You Tan. Molecular Mechanisms of Selenium Mitigating Lead Toxicity in Chickens via Mitochondrial Pathway: Selenoproteins, Oxidative Stress, HSPs, and Apoptosis. Toxics. vol 11. issue 9. 2023-09-27. PMID:37755744. furthermore, we further demonstrated that pb elevated four hsps (hsp27, hsp40, hsp70, and hsp90), as well as hsp70 took part in the molecular mechanism of pb-caused apoptosis. 2023-09-27 2023-10-07 chicken
James Patrick Heiserman, Zenab Minhas, Elahe Nikpayam, Dong-Joo Cheo. Targeting Heat Shock Protein 27 and Fatty Acid Oxidation Augments Cisplatin Treatment in Cisplatin-Resistant Ovarian Cancer Cell Lines. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628819. ros depletion with the compound n-acetyl cysteine (nac) attenuated cisplatin-induced upregulation of hsp27, fao, and markers of apoptosis and ferroptosis in cisplatin-resistant ovarian cancer cell lines. 2023-08-26 2023-09-07 Not clear
Dilay Karademir, Aykut Özgü. Small molecule heat shock protein 27 inhibitor J2 decreases ovarian cancer cell proliferation via induction of apoptotic pathways. Medical oncology (Northwood, London, England). vol 40. issue 9. 2023-07-26. PMID:37493998. here, we investigated the apoptosis inducer role of the j2 compound (hsp27 inhibitor) in human ovarian cancer cell lines (skov3 and ovcar-3). 2023-07-26 2023-08-14 human
Yahiya Ibrahim Yahiya, Najah Rayish Hadi, Ahmed Abu Raghif, Noor Ghaffar Said Al Haboob. Protective effect of IAXO-102 on renal ischemia-reperfusion injury in rats. Journal of medicine and life. vol 16. issue 4. 2023-06-12. PMID:37305825. iaxo-102 also decreased apoptosis by reducing pro-apoptotic bax and increasing anti-apoptotic bcl-2 without impacting hsp27. 2023-06-12 2023-08-14 rat
Yifei Zou, Henghe Shi, Ning Liu, He Wang, Xianjing Song, Bin Li. Mechanistic insights into heat shock protein 27, a potential therapeutic target for cardiovascular diseases. Frontiers in cardiovascular medicine. vol 10. 2023-05-30. PMID:37252119. herein, we comprehensively and systematically summarize the involvement of hsp27 and its phosphorylated form in pathophysiological processes, including oxidative stress, inflammatory responses, and apoptosis, and further explore the potential mechanisms and possible roles of hsp27 in the diagnosis and treatment of cardiovascular diseases. 2023-05-30 2023-08-14 Not clear
Haibo Gong, Chengmei Zhang, Wei Cao, Shanshan Yao, Xin Chang, Zhiying Miao, Ye Qian, Haijing Den. [Expression of HSP27 and BAX/BCL-2 apoptosis factor in silicosis rat model of fibrosis]. Wei sheng yan jiu = Journal of hygiene research. vol 52. issue 2. 2023-04-16. PMID:37062688. [expression of hsp27 and bax/bcl-2 apoptosis factor in silicosis rat model of fibrosis]. 2023-04-16 2023-08-14 rat
Haibo Gong, Chengmei Zhang, Wei Cao, Shanshan Yao, Xin Chang, Zhiying Miao, Ye Qian, Haijing Den. [Expression of HSP27 and BAX/BCL-2 apoptosis factor in silicosis rat model of fibrosis]. Wei sheng yan jiu = Journal of hygiene research. vol 52. issue 2. 2023-04-16. PMID:37062688. to study the expression of heat shock protein 27(hsp27), bax and bcl-2 apoptosis in silicosis rat model, and to explore the correlation between hsp27 and bax and bcl-2 apoptosis. 2023-04-16 2023-08-14 rat
Suroor Fatima Rizvi, Adria Hasan, Sana Parveen, Snober S Mi. Untangling the complexity of heat shock protein 27 in cancer and metastasis. Archives of biochemistry and biophysics. 2023-02-04. PMID:36738981. hsp27 influences various cellular pathways associated with cancer cell survival and growth such as apoptosis, autophagy, metastasis, angiogenesis, epithelial to mesenchymal transition, etc. 2023-02-04 2023-08-14 Not clear
Junichi Okada, Eijiro Yamada, Tsugumichi Saito, Kazuya Okada, Masanobu Yamada, Kihachi Ohshima, Shuichi Okad. FAM83G-based peptide induces apoptosis on cultured liver cancer cell. Protein and peptide letters. 2022-09-29. PMID:36173053. background previously, af-956, which contains s356 of fam83g and an n-terminal antenna peptide for entry into colon cancer cells, is markedly antiproliferative compared to a control peptide (af-859), which lacks the n-terminal antenna peptide, by inducing apoptosis via the inhibition of hsp27 phosphorylation at residues s15 and s82. 2022-09-29 2023-08-14 Not clear
Debora Singer, Verena Ressel, Matthias B Stope, Sander Bekeschu. Heat Shock Protein 27 Affects Myeloid Cell Activation and Interaction with Prostate Cancer Cells. Biomedicines. vol 10. issue 9. 2022-09-23. PMID:36140293. the small heat shock protein 27 (hsp27) is highly expressed under oxidative stress conditions, mediating anti-oxidative effects and blocking apoptosis. 2022-09-23 2023-08-14 human
Debora Singer, Verena Ressel, Matthias B Stope, Sander Bekeschu. Heat Shock Protein 27 Affects Myeloid Cell Activation and Interaction with Prostate Cancer Cells. Biomedicines. vol 10. issue 9. 2022-09-23. PMID:36140293. since medical gas plasma treatment subjects cancer cells to a multitude of reactive oxygen species (ros), inducing apoptosis and immunomodulation, probable effects of hsp27 should be investigated. 2022-09-23 2023-08-14 human
Nina Aghazadeh, Elmira Aboutalebi Vand Beilankouhi, Farima Fakhri, Morad Kohandel Gargari, Parisa Bahari, Aliasghar Moghadami, Zhila Khodabandeh, Mohammad Valil. Involvement of heat shock proteins and parkin/α-synuclein axis in Parkinson's disease. Molecular biology reports. 2022-09-12. PMID:36097120. recent findings have shown that hsps, especially hsp27 and hsp70, play a pivotal role in regulating apoptosis by influencing the factors involved in the apoptosis pathway. 2022-09-12 2023-08-14 Not clear
Haruna Isiyaku Umar, Adeola Temitayo Ajayi, Nobendu Mukerjee, Abdullahi Tunde Aborode, Mohammad Mehedi Hasan, Swastika Maitra, Ridwan O Bello, Hafsat O Alabere, Afees A Sanusi, Olamide O Awolaja, Mohammed M Alshehri, Prosper O Chukwuemeka, Nada H Aljarba, Saad Alkahtani, Sumira Malik, Athanasios Alexiou, Arabinda Ghosh, Md Habibur Rahma. Discovery of Novel HSP27 Inhibitors as Prospective Anti-Cancer Agents Utilizing Computer-Assisted Therapeutic Discovery Approaches. Cells. vol 11. issue 15. 2022-08-12. PMID:35954254. hsp27 suppresses apoptosis and cytoskeletal reorganization. 2022-08-12 2023-08-14 human
Sara Mirzaei, Milad Iranshahy, Hamid Gholamhosseinian, Maryam M Matin, Fatemeh B Rassoul. Urolithins increased anticancer effects of chemical drugs, ionizing radiation and hyperthermia on human esophageal carcinoma cells in vitro. Tissue & cell. vol 77. 2022-06-09. PMID:35679683. to further elucidate the effects of ua, we used flow cytometry for investigation of induced apoptosis, and qrt-pcr for evaluating changes in the expression of hsp27, ccnd1 and bcl2. 2022-06-09 2023-08-14 human
Xiao-Yan Zhou, Jing-Yi Sun, Wei-Qi Wang, Shu-Xian Li, Han-Xia Li, Hui-Juan Yang, Ming-Feng Yang, Hui Yuan, Zong-Yong Zhang, Bao-Liang Sun, Jin-Xiang Ha. TAT-HSP27 Peptide Improves Neurologic Deficits Frontiers in cellular neuroscience. vol 16. 2022-05-16. PMID:35573833. in rat sah model, hsp27 of csf is first increased and then obviously declined; overexpression of hsp27, not knockdown of hsp27, attenuates sah-induced neurological deficit and cell apoptosis in the basal cortex; and overexpression of hsp27 effectively suppresses sah-elevated activation of mitogen-activated protein kinase kinase 4 (mkk4), the c-jun n-terminal kinase (jnk), c-jun, and caspase-3. 2022-05-16 2023-08-13 rat
Marios Lampros, Nikolaos Vlachos, Spyridon Voulgaris, George A Alexio. The Role of Hsp27 in Chemotherapy Resistance. Biomedicines. vol 10. issue 4. 2022-04-23. PMID:35453647. despite its protective role in normal cell physiology, hsp27 overexpression in various cancer cell lines is implicated in tumor initiation, progression, and metastasis through various mechanisms, including modulation of the swh pathway, inhibition of apoptosis, promotion of emt, adaptation of cscs in the tumor microenvironment and induction of angiogenesis. 2022-04-23 2023-08-13 Not clear