| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao Han, Jiayan Huang, Jia Lu, Feng He, Fang Wang, Shuangfeng Li, Hao Zhong, Haiyang Yu, Weiling P. Active compounds and potential targets of Shuganning injection in the treatment of hepatocellular carcinoma by network pharmacology and in vitro validation. Naunyn-Schmiedeberg's archives of pharmacology vol issue 2023 36869905 |
the in vitro test of the effects and mechanism of vanillin and baicalein was elucidated by mtt, western blot, immunofluorescence, and apoptosis analysis. |
2023-03-04 |
2023-03-06 |
Not clear |
| Qing Zhou, Deshui Kong, Wenzhi Li, Zhengzheng Shi, Yao Liu, Rui Sun, Xiaohong Ma, Chunping Qiu, Zhiming Liu, Yixin Hou, Jie Jian. LncRNA HOXB-AS3 binding to PTBP1 protein regulates lipid metabolism by targeting SREBP1 in endometrioid carcinoma. Life sciences vol issue 2023 36858312 |
colony formation assay, mtt assay, flow cytometry and apoptosis assay, and transwell assay were used to verify the role of hoxb-as3 in ec. |
2023-03-01 |
2023-03-06 |
Not clear |
| Saad Alkahtani, Norah S Al-Johani, Saud Alarifi, Mohd Afza. Cytotoxicity Mechanisms of Blue-Light-Activated Curcumin in T98G Cell Line: Inducing Apoptosis through ROS-Dependent Downregulation of MMP Pathways. International journal of molecular sciences vol 24 issue 4 2023 36835252 |
the therapeutic effect of curcumin, in both the absence and presence of blue light, was measured by the mtt assay and apoptosis progression using flow cytometry. |
2023-02-25 |
2023-03-06 |
Not clear |
| L\\xc3\\xbc Guohua, Ren Wu, Bing Wang, Li Lei, Yunchao Li, Xinyi Li, Haoyu He, Xiaoxiao Wang, Kuang Le. SPTLC2 ameliorates chondrocyte dysfunction and extracellular matrix metabolism disturbance in vitro and in vivo in osteoarthritis. Experimental cell research vol issue 2023 36828166 |
cell viability and apoptosis were measured using mtt and flow cytometry analyses; sptlc2 overexpression enhanced the oa chondrocyte viability and decreased apoptotic rate. |
2023-02-24 |
2023-03-06 |
rat |
| Gholam Abbas Ghorbankhani, Ali Mohammadi, Nasrin Kazemipur, Solmaz Morovati, Behrouz Gharesi Fard, Saeed Nazifi Habibabadi, Mahdi Hashempour Sadeghia. Apoptotic activity of Newcastle disease virus in comparison with nisin A in MDA-MB-231 cell line. Veterinary research forum : an international quarterly journal vol 14 issue 1 2023 36816859 |
the oncolytic effects of these treatments were analyzed by different cytotoxic and apoptosis techniques including trypan blue staining, mtt assay, acridine orange (eb/ao) staining, colony assay and flow cytometry over time. |
2023-02-23 |
2023-03-06 |
Not clear |
| Zahra Ghaemi, Seyed Javad Mowla, Bahram Mohammad Soltan. Novel splice variants of LINC00963 suppress colorectal cancer cell proliferation via miR-10a/miR-143/miR-217/miR-512-mediated regulation of PI3K/AKT and Wnt/\\xce\\xb2-catenin signaling pathways. Biochimica et biophysica acta. Gene regulatory mechanisms vol issue 2023 36804476 |
at cellular levels, linc00963-v2/-v3 overexpression suppressed cell proliferation, viability, and migration while increasing the apoptosis of crc cell lines, detected by pi flow cytometry, colony formation, mtt, rt-qpcr, wound-healing, transwell, annexinv-pe/7aad, caspase3/7 activity assays, and hoechst/pi-ao/eb staining. |
2023-02-22 |
2023-03-06 |
Not clear |
| Fei Li, Aiqin Niu, Kangjun Zhao, Jianbing Feng, Ying Che. GRIM-19 in asthenozoospermia regulates GC-2 spd cell proliferation, apoptosis and migration. Scientific reports vol 13 issue 1 2023 36813832 |
mtt assays were used to assess cell proliferations, flow cytometry was performed to assess cell apoptosis, wound\xe2\x80\x91healing was performed to measure cell migration. |
2023-02-22 |
2023-03-06 |
Not clear |
| Jinsu Hwang, Jong-Seong Park, Mahesh Ramalingam, Byeong C Kim, Han-Seong Jeong, Sujeong Jan. Neuroprotective Effects of a Wnt Antagonist in Quinolinic Acid-Induced Excitotoxicity in N18D3 Cells. Cellular and molecular biology (Noisy-le-Grand, France) vol 68 issue 8 2023 36800814 |
an mtt assay and dapi staining were used to evaluate cell viability and apoptosis, respectively, demonstrating that box5 protected the cells from apoptotic death. |
2023-02-21 |
2023-03-06 |
Not clear |
| Faranak Gholipour, Mohammad Amini, Behzad Baradaran, Ahad Mokhtarzadeh, Morteza Eskandan. Anticancer properties of curcumin-treated Lactobacillus plantarum against the HT-29 colorectal adenocarcinoma cells. Scientific reports vol 13 issue 1 2023 36801895 |
moreover, flow cytometry analyses of apoptosis and cell cycle confirmed dapi staining and mtt assay results and stipulated the increased occurrence of programmed cell death (apoptosis) in cur-cfs-treated cells (~\xe2\x80\x8957.65%) compared to cfs-treated cells (~\xe2\x80\x8947%). |
2023-02-21 |
2023-03-06 |
Not clear |
| Hongguang Sheng, Jun Xiong, Danying Yan. Protective Effect of Sevoflurane Preconditioning on Cardiomyocytes Against Hypoxia/Reoxygenation Injury by Modulating Iron Homeostasis and Ferroptosis. Cardiovascular toxicology vol issue 2023 36800141 |
mtt was taken to assess the viability of each group of cells, flow cytometry to detect cell apoptosis, and qrt-pcr or western blot to detect the expression of iron metabolism-related proteins and apoptosis-related proteins in the cells. |
2023-02-17 |
2023-03-06 |
rat |
| Mariam Sanjari-Pour, Nassim Faridi, Ping Wang, S Zahra Bathai. Protective effect of saffron carotenoids against amyloid beta-induced neurotoxicity in differentiated PC12 cells via the unfolded protein response and autophagy. Phytotherapy research : PTR vol issue 2023 36794286 |
the mtt assay, flow cytometry, and elevated p-jnk, p-bcl-2, and c-parp indicated the a\xce\xb2os-induced apoptosis in differentiated pc12 cells. |
2023-02-16 |
2023-03-06 |
Not clear |
| Lei Jin, Karrie Mei-Yee Kiang, Stephen Yin Cheng, Gilberto Ka-Kit Leun. Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O Laboratory investigation; a journal of technical methods and pathology vol 102 issue 2 2023 36775408 |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flowcytometry and colony formation assays demonstrated that nct503 worked synergistically with tmz in suppressing gbm cell growth and inducing apoptosis in t98g and u118 cells in vitro. |
2023-02-12 |
2023-03-06 |
Not clear |
| Jing Zhang, Meng Chen, Jie Liu, Dongdong Peng, Zong Dai, Xiaoyong Zou, Zhanchao L. A Knowledge-Graph-Based Multimodal Deep Learning Framework for Identifying Drug-Drug Interactions. Molecules (Basel, Switzerland) vol 28 issue 3 2023 36771157 |
moreover, the identified interactions between topotecan and dantron by kgcn_nfm were validated through mtt assays, apoptosis experiments, cell cycle analysis, and molecular docking. |
2023-02-11 |
2023-03-06 |
Not clear |
| Chenxi Wang, Chenyang Huang, Jiali Wang, Jianfeng Ye, Zhiqiang Xue, Jian Zhang, Yuke Re. Ginsenoside Rg5 attenuates hypoxia-induced cardiomyocyte apoptosis via regulating theAkt pathway. Chemical biology & drug design vol issue 2023 36762503 |
in this study, following isolation and culture of ventricular myocardial cells from neonatal rats, the appropriate concentration of rg5 was determined using the mtt assay, the effect of rg5 on apoptosis was assessed employing tunel staining and flow cytometry assays. |
2023-02-10 |
2023-03-06 |
rat |
| Wang Yiou, Wang Zhihong, Zhu Shibai, Li Shanni, Qian Wenwe. MiR-326 regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis. Human cell vol issue 2023 36749538 |
mtt assay and flow cytometry were conducted to explore the biological function of mir-326.\xc2\xa0our data\xc2\xa0revealed that the upregulation of mir-326\xc2\xa0suppressed cell proliferation and induced apoptosis in ra-fls. |
2023-02-07 |
2023-03-06 |
mouse |
| Shurong Zheng, Weida Fu, Qidi Huang, Jieyu Zhou, Kangkang Lu, Junwei Gu, Ruimin Ma, Guilong Gu. LncRNA PRKCQ-AS1 regulates paclitaxel resistance in triple-negative breast cancer cells through miR-361-5p/PIK3C3 mediated autophagy. Clinical and experimental pharmacology & physiology vol issue 2023 36732923 |
cell viability, apoptosis, migration, and invasion were assessed by performing mtt, flow cytometry assay, and transwell assay. |
2023-02-03 |
2023-03-06 |
Not clear |
| Xiujuan Deng, Haigen Wu, Liping Xiong, Mouxi Wu, Jinfu Cao, Jing Liu, Wenyang Xi. MiR-92a regulates PTEN/Akt signaling axis to promote paclitaxel resistance in ovarian cancer cells. Acta biochimica Polonica vol issue 2023 36735765 |
the cell viability and apoptosis were detected by mtt, colony formation and flow cytometry assay, respectively. |
2023-02-03 |
2023-03-06 |
Not clear |
| Siyuan Chen, Huili Ma, Mintao Li, Zhuting Jia, Xi Chen, Naitong B. Long Noncoding RNA NORAD Promotes Fracture Healing through Interacting with Osteoblast Differentiation via Targeting miR-26a. BioMed research international vol 2023 issue 2023 36726840 |
the proliferation, differentiation, and apoptosis of osteoblasts were analyzed by mtt assay, elisa, and flow cytometry. |
2023-02-02 |
2023-03-06 |
Not clear |
| Cheng-Hsun Lin, Kuang-Hsuan Lin, Hsiang-Ju Ku, Kun-Ching Lee, Song-Shei Lin, Fei-Ting Hs. Amentoflavone induces caspase-dependent/-independent apoptosis and dysregulates cyclin-dependent kinase-mediated cell cycle in colorectal cancer in vitro and in vivo. Environmental toxicology vol issue 2023 36727907 |
we identified the cytotoxicity, apoptosis effect, cell cycle alteration, dna damage induction and tumor progression inhibition of amentoflavone in ht-29 model by using mtt assay, flow cytometry, immunofluorescence (if) staining, western blotting and animal experiments. |
2023-02-02 |
2023-03-06 |
Not clear |
| Jie Feng, Wei He, Jian Xia, Qing Huang, Jie Yang, Wen-Ping Gu, Ning Zhang, Yun-Hai Li. Human umbilical cord mesenchymal stem cells-derived exosomal circDLGAP4 promotes angiogenesis after cerebral ischemia-reperfusion injury by regulating miR-320/KLF5 axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 37 issue 3 2023 36723877 |
then, cell viability, migration, apoptosis, and tube formation were measured by mtt, flow cytometry, transwell, and tube formation assays. |
2023-02-01 |
2023-03-06 |
rat |