| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huifang Zhang, Yudan Zhang, Kaixuan Xu, Lawen Wang, Xin Zhou, Mingge Yang, Jiangli Xie, Hui L. Inhibition of FLT1 Attenuates Neurodevelopmental Abnormalities and Cognitive Impairment in Offspring Caused by Maternal Prenatal Stress. Applied biochemistry and biotechnology. 2023-11-18. PMID:37979086. |
the apoptosis level of hippocampal neurons and the expression of nmdars were detected by mtt assay, tunel assay, and western blot. |
2023-11-18 |
2023-11-20 |
rat |
| Ji He, Piyush Bugde, Jiawei Li, Riya Biswas, Siting Li, Xuewei Yang, Fang Tian, Zimei Wu, Yan L. Multidrug resistance protein 5 affects cell proliferation, migration and gemcitabine sensitivity in pancreatic cancer MIA Paca‑2 and PANC‑1 cells. Oncology reports. vol 51. issue 1. 2023-11-17. PMID:37975256. |
mrp5‑regulated gemcitabine sensitivity was assessed by mtt, prestoblue and apoptosis assays. |
2023-11-17 |
2023-11-20 |
human |
| Ying-Jie Zhu, Hu-Lin Chen, Xin-Jie Cai, Bang-le Zhan, Xiao-Ming Li. Naringin acts as a TRPV1 antagonist to attenuate UVB-induced senescence and damage in HaCaT cells. Chemical biology & drug design. 2023-11-09. PMID:37945519. |
analysis was performed using the mtt assay to assess cell viability, flow cytometry to measure the apoptosis level, sa-β-gal staining to observe cellular senescence, and western blot to assess protein levels of trpv1, p16, p53, p21, matrix metalloproteinase (mmp)-1, and mmp-9. |
2023-11-09 |
2023-11-20 |
human |
| Yiyang Li, Nyuk Ling Ma, Huiling Chen, Jiateng Zhong, Dangquan Zhang, Wanxi Peng, Su Shiung Lam, Yafeng Yang, Xiaochen Yue, Lijun Yan, Ting Wang, Bjarne Styrishave, Tomasz Maciej Ciesielski, Christian Sonn. High-throughput screening of ancient forest plant extracts shows cytotoxicity towards triple-negative breast cancer. Environment international. vol 181. 2023-11-04. PMID:37924601. |
first, to study the effects on viability of the plant extracts, we used a mtt and cck-8 cytotoxicity assay employing triple-negative breast cancer (tnbc) mda-mb-231 and normal epithelial mcf-10a cell lines and cell cycle arrest to estimate apoptosis using flow cytometry for the most potent three speices. |
2023-11-04 |
2023-11-08 |
Not clear |
| Zhen Liu, Hong Zhang, Xiaoxia H. Analysis of the expression and mechanism of follistatin‑like protein 1 in cervical cancer. Oncology reports. vol 50. issue 6. 2023-10-27. PMID:37888756. |
the effects of abnormal expression of fstl1 on cervical cancer cells were assessed using colony formation, mtt, wound‑healing, transwell, apoptosis, and nude mouse tumorigenicity assays. |
2023-10-27 |
2023-11-08 |
mouse |
| Albert Armoo, Tanner Diemer, Abigail Donkor, Jerrod Fedorchik, Severine Van Slambrouck, Rachel Willand-Charnley, Brian A Logu. Methimazole, an Effective Neutralizing Agent of the Sulfur Mustard Derivative 2-Chloroethyl Ethyl Sulfide. ACS bio & med chem Au. vol 3. issue 5. 2023-10-26. PMID:37876493. |
cell viability, relative loss of extracellular matrix adhesions, and apoptosis caused by cees were measured via mtt, cell-matrix adhesion (cma), and apoptosis protein marker assays, respectively. |
2023-10-26 |
2023-11-08 |
human |
| Chuntang Qin, Shuyan Liu, Weibin Chen, Dan Xue, Tianli Guo, Baojiang W. HuR-induced circ_0082319 contributes to hepatocellular carcinoma by elevating PTK2 through miR-505-3p. Naunyn-Schmiedeberg's archives of pharmacology. 2023-10-25. PMID:37878047. |
cell viability, proliferation, apoptosis, invasion, and angiogenesis were measured using (4-5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) assay, 5-ethynyl-2'-deoxyuridine (edu), flow cytometry, transwell, and tube formation assays. |
2023-10-25 |
2023-11-08 |
human |
| Xinchan Jiang, Xiaobo Che. Endometrial cell‑derived exosomes facilitate the development of adenomyosis via the IL‑6/JAK2/STAT3 pathway. Experimental and therapeutic medicine. vol 26. issue 5. 2023-10-24. PMID:37869633. |
mtt, flow cytometry and wound-healing assays were performed to examine am cell proliferation, apoptosis, cell cycle distribution and migration. |
2023-10-24 |
2023-11-08 |
Not clear |
| Zhigang Yang, Liguo Yang, Jun Zhang, Chenzeyue Qian, Yi Zha. AS602801 treatment suppresses breast cancer metastasis to the brain by interfering with gap-junction communication by regulating Cx43 expression. Drug development research. 2023-10-20. PMID:37859299. |
mtt (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay and flow cytometry were performed to evaluate the proliferation and apoptosis of breast cancer cells co-cultivated with astrocytes. |
2023-10-20 |
2023-11-08 |
mouse |
| Stephanie Verbeke, Aurelien Bourdon, Jean-Philippe Guégan, Laura Leroy, Vanessa Chaire, Elodie Richard, Alban Bessede, Antoine Italian. Antitumor effects of PRMT5 inhibition in sarcomas. Cancer research communications. 2023-10-20. PMID:37861293. |
we then used the potent and selective gsk3326595 (gsk595) compound to investigate the antitumor effect of the pharmacological inhibition of prmt5 in vitro via mtt, apoptosis, cell cycle, clonogenicity and proliferation assays. |
2023-10-20 |
2023-11-08 |
Not clear |
| Shahbaz Ahmed, Masood Nadeem, Irfan Hussain, Sana Fatima, Saleha Anwar, Moshahid Alam Rizvi, Md Imtaiyaz Hassan, Mohammad Tabis. Preparation of nanoformulation of 5-fluorouracil to improve anticancer efficacy: integrated spectroscopic, docking, and MD simulation approaches. Journal of biomolecular structure & dynamics. 2023-10-18. PMID:37850451. |
the cytotoxicity and apoptosis profiles confirmed that n5-fu enhanced the anticancer effect of the pure drug in hct-116 cells, as evident from mtt assay, fluorescence microscopy, and facs analysis. |
2023-10-18 |
2023-11-08 |
Not clear |
| Sara Cheleschi, Nicola Veronese, Serafino Carta, Giulia Collodel, Maria Bottaro, Elena Moretti, Roberta Corsaro, Marcella Barbarino, Antonella Fioravant. MicroRNA as Possible Mediators of the Synergistic Effect of Celecoxib and Glucosamine Sulfate in Human Osteoarthritic Chondrocyte Exposed to IL-1β. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834442. |
cell viability was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, apoptosis and reactive oxygen species (ros) by cytometry, nitric oxide (no) by griess method. |
2023-10-14 |
2023-10-15 |
human |
| Su-Ji Jeon, Eun-Young Choi, Eun-Ji Han, Sang-Woo Lee, Jun-Mo Moon, Soo-Hyun Jung, Ji-Youn Jun. Piperlongumine induces apoptosis via the MAPK pathway and ERK‑mediated autophagy in human melanoma cells. International journal of molecular medicine. vol 52. issue 6. 2023-10-13. PMID:37830157. |
when pl was applied following treatment with autophagy inhibitors 3‑methyladenine and hydroxychloroquine, autophagy exhibited a cytoprotective effect against apoptosis in mtt assay. |
2023-10-13 |
2023-10-15 |
human |
| Zheng Li, Weiwei Zhang, Ji Xu, Xiaoye M. Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation. Journal of molecular histology. 2023-10-13. PMID:37831422. |
cell proliferation and apoptosis were determined using mtt assay, tunel staining, and flow cytometry. |
2023-10-13 |
2023-10-15 |
mouse |
| Sheng Hu, Qiang Zhou, Qiang Lu, Xi Guo, Yong Wang, Yi-Xing Dua. miR-199a/214 cluster enhances prostate cancer sensitiveness to nimotuzumab via targeting TBL1XR1. The Kaohsiung journal of medical sciences. 2023-09-29. PMID:37772770. |
in this study, we conducted an mtt assay to assess cell proliferation and utilized flow cytometry to evaluate cell apoptosis and cell cycle arrest. |
2023-09-29 |
2023-10-07 |
human |
| Negin Riazi-Tabrizi, Mohammad Khalaj-Kondori, Sahar Safaei, Mohammad Amini, Hamidreza Hassanian, Mohadeseh Maghsoudi, Shima Hasani, Behzad Baradara. NRF2 Suppression Enhances the Susceptibility of Pancreatic Cancer Cells, Miapaca-2 to Paclitaxel. Molecular biotechnology. 2023-09-23. PMID:37740817. |
after that, cell viability was measured by mtt assay and apoptosis induction by annexin v-fitc/pi staining test. |
2023-09-23 |
2023-10-07 |
Not clear |
| Shengyou Ge, Kexin Wang, Yuxiang Meng, Zongxuan He, Xiaochen Yang, Wei Shang, Lin Wan. Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway. Medical oncology (Northwood, London, England). vol 40. issue 10. 2023-09-21. PMID:37733085. |
cell proliferation, apoptosis and migration were detected by colony formation, mtt, flow cytometry, wound healing and transwell. |
2023-09-21 |
2023-10-07 |
Not clear |
| Guangkui Bu, Gang Chen, Juan Li, Dan Wu, Jiangtao Lia. EXPRESS: Bifidobacterium bifidum BGN4 fractions ameliorate palmitic acid-induced hepatocyte ferroptosis by inhibiting SREBP1-CYP2E1 pathway. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2023-09-19. PMID:37723650. |
lo2 cell proliferation was examined using mtt and edu assays, while its apoptosis was evaluated by flow cytometry. |
2023-09-19 |
2023-10-07 |
Not clear |
| Huibo Li, Jinxiao Hou, Yueyue Fu, Yanqiu Zhao, Jie Liu, Dan Guo, Ruiqi Lei, Yiting Wu, Linqing Tang, Shengjin Fa. miR-603 promotes cell proliferation and differentiation by targeting TrkB in acute promyelocytic leukemia. Annals of hematology. 2023-09-19. PMID:37726492. |
proliferation was measured using an mtt assay, while apoptosis, cell cycle and cd11b expression were analyzed using flow cytometry. |
2023-09-19 |
2023-10-07 |
Not clear |
| Qipu Yin, Hongxia Yang, Lun Fang, Qi Wu, Shan Gao, Yadi Wu, Lu Zho. Fibroblast growth factor 23 regulates hypoxia‑induced osteoblast apoptosis through the autophagy‑signaling pathway. Molecular medicine reports. vol 28. issue 5. 2023-09-15. PMID:37711045. |
apoptosis was analyzed by mtt assay, fluorescein diacetate and ethidium bromide staining, flow cytometry and rt‑qpcr and western blotting were used to verify the mrna and protein levels of apoptosis‑ and autophagy‑related gene mrna. |
2023-09-15 |
2023-10-07 |
Not clear |