| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhuo Xiang, Lingling Xu, Yizhu Shan, Xi Cui, Bojing Shi, Yuan Xi, Panxing Ren, Xuemei Zheng, Chaochao Zhao, Dan Luo, Zhou L. Tumor microenviroment-responsive self-assembly of barium titanate nanoparticles with enhanced piezoelectric catalysis capabilities for efficient tumor therapy. Bioactive materials. vol 33. 2023-12-07. PMID:38059123. |
tma-bto nps exhibited differential cytotoxicity against tumor cells and normal cells, and the stronger piezoelectric catalysis and mechanical damage induced by the assemblies resulted in significant apoptosis of mouse breast cancer cells (4t1); while there was little damage to mouse embryo osteoblast precursor cells (mc3t3-e1) under the same treatment conditions. |
2023-12-07 |
2023-12-10 |
mouse |
| Shihang Xu, Weicong Luo, Minghui Zhu, Lei Zhao, Lijuan Gao, Hong Liang, Zhenlei Zhang, Feng Yan. Human Serum Albumin-Platinum(II) Agent Nanoparticles Inhibit Tumor Growth Through Multimodal Action Against the Tumor Microenvironment. Molecular pharmaceutics. 2023-11-28. PMID:38015620. |
in addition, the hsa-his242-pt-dp44mt nps were found to kill cancer cells by inducing apoptosis, autophagy, and inhibiting angiogenesis. |
2023-11-28 |
2023-12-07 |
human |
| Siyi Liu, Min Liu, Jingya Xiu, Tian Zhang, Bowen Zhang, Dongyun Cun, Chunrong Yang, Kexin Li, Jiulong Zhang, Xiuli Zha. Celastrol-Loaded Bovine Serum Albumin Nanoparticles Target Inflamed Neutrophils for Improved Rheumatoid Arthritis Therapy. Acta biomaterialia. 2023-11-28. PMID:38013018. |
studies have demonstrated that cbr nps can selectively target circulating ines and induce ines apoptosis. |
2023-11-28 |
2023-11-29 |
mouse |
| Siyi Liu, Min Liu, Jingya Xiu, Tian Zhang, Bowen Zhang, Dongyun Cun, Chunrong Yang, Kexin Li, Jiulong Zhang, Xiuli Zha. Celastrol-Loaded Bovine Serum Albumin Nanoparticles Target Inflamed Neutrophils for Improved Rheumatoid Arthritis Therapy. Acta biomaterialia. 2023-11-28. PMID:38013018. |
cbr nps were prepared for the first time to induce apoptosis of ines; cbr nps could inhibit the release of nets while inducing apoptosis of ines in vivo and vitro cellular experiments; cbr nps had favorable anti-inflammatory effects and low toxicity side-effects in collagen-induced arthritis (cia) mouse models. |
2023-11-28 |
2023-11-29 |
mouse |
| Melayshia McFadden, Santosh Kumar Singh, Briana Kinnel, Sooryanarayana Varambally, Rajesh Sing. The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer. Journal of ovarian research. vol 16. issue 1. 2023-11-22. PMID:37990267. |
the present study shows that targeting folate receptor alpha (frα) through planetary ball milling (pbm) nanoparticles (nps) induces apoptosis in ovca cells. |
2023-11-22 |
2023-11-29 |
Not clear |
| Thangavelu Indumathi, Inbavalli Kumaresan, Jagadeesh Suriyaprakash, Abdullah A Alarfaj, Abdurahman Hajinur Hirad, Ravindran Jaganathan, Maghimaa Mathanmohu. Synthesis and characterization of 4-nitro benzaldehyde with ZnO-based nanoparticles for biomedical applications. Journal of basic microbiology. 2023-11-21. PMID:37988661. |
in addition, the influence of synthesized nps on cell apoptosis, cell viability, mitochondrial membrane potential (mmp), endogenous reactive oxygen species (ros) production, apoptosis, and cell adhesion was also examined. |
2023-11-21 |
2023-11-29 |
Not clear |
| Thangavelu Indumathi, Inbavalli Kumaresan, Jagadeesh Suriyaprakash, Abdullah A Alarfaj, Abdurahman Hajinur Hirad, Ravindran Jaganathan, Maghimaa Mathanmohu. Synthesis and characterization of 4-nitro benzaldehyde with ZnO-based nanoparticles for biomedical applications. Journal of basic microbiology. 2023-11-21. PMID:37988661. |
the cell adhesion test revealed that 4nbzno nps reduced cell adhesion and may promote apoptosis of cancer cells because of enhanced ros levels. |
2023-11-21 |
2023-11-29 |
Not clear |
| Jing-Qing Le, Xun-Huan Song, Ling-Wu Tong, Ying-Qi Lin, Ke-Ke Feng, Yi-Fan Tu, Yong-Shan Hu, Jing-Wei Sha. Dual-drug controllable co-assembly nanosystem for targeted and synergistic treatment of hepatocellular carcinoma. Journal of colloid and interface science. vol 656. 2023-11-21. PMID:37989051. |
furthermore, these nps caused more significant mitochondrial membrane potential reduction and cell apoptosis. |
2023-11-21 |
2023-11-29 |
mouse |
| Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Son. Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment international. vol 181. 2023-11-02. PMID:37918063. |
mechanically, zno nps triggered fatty acid accumulation in gc-1 cells through protein kinase b (akt)/mammalian target of rapamycin (mtor) signaling and peroxisome proliferator-activated receptor alpha (pparα)/acyl-coa oxidase 1 (acox1) axis, contributing to cell apoptosis. |
2023-11-02 |
2023-11-08 |
rat |
| Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Son. Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment international. vol 181. 2023-11-02. PMID:37918063. |
in vitro and in vivo experiments verified that zno nps disrupted blood-testis barrier formation and growth factors synthesis, which subsequently inhibited the proliferation and induced the apoptosis of spermatogonia. |
2023-11-02 |
2023-11-08 |
rat |
| Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Son. Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment international. vol 181. 2023-11-02. PMID:37918063. |
as for the macrophages, zno nps activated oxidative stress of raw264.7 cells through nuclear factor erythroid 2-related factor 2 (nrf2)/heme oxygenase-1 (ho-1) pathway and promoted cell apoptosis through extracellular signal-regulated kinase (erk) 1/2 pathway. |
2023-11-02 |
2023-11-08 |
rat |
| Rohan Ghadi, Pawan Kumar Pandey, Akash Gabhale, Aaradhya Wadikar, M Dharshini, Kaushik Kuche, Tushar Date, Sanyog Jai. Genipin-Crosslinked Albumin Nanoparticles Containing Neratinib and Silibinin: A Dual-Death Therapy for Triple Negative Breast Cancer. International journal of pharmaceutics. 2023-11-02. PMID:37918494. |
a combined therapy using neratinib (ntb; ferroptosis inducer) and silibinin (slb; apoptosis inducer) via albumin-based nanocarriers (n-s alb nps) was explored to target tnbc. |
2023-11-02 |
2023-11-08 |
Not clear |
| Yu-Chen Lo, Wen-Jen Li. Improve BBB Penetration and Cytotoxicity of Palbociclib in U87-MG Glioblastoma Cells Delivered by Dual Peptide Functionalized Nanoparticles. Pharmaceutics. vol 15. issue 10. 2023-10-30. PMID:37896189. |
moreover, pbc@nps significantly enhanced u87-mg glioma cell apoptosis by 2.3-6.5 folds relative to pbc, where the dual-peptide modified nps was the most effective one. |
2023-10-30 |
2023-11-08 |
Not clear |
| Miaomiao Yuan, Tong Chen, Lu Jin, Peng Zhang, Luoyijun Xie, Shuyi Zhou, Lianfeng Fan, Li Wang, Cai Zhang, Ning Tang, LiHao Guo, Chengmei Xie, Yanhong Duo, Ling Li, Leilei Sh. A carrier-free supramolecular nano-twin-drug for overcoming irinotecan-resistance and enhancing efficacy against colorectal cancer. Journal of nanobiotechnology. vol 21. issue 1. 2023-10-30. PMID:37898773. |
the ir and nir self-assembled nano-twin-drug of (nir-ir nps) could enhance the therapeutic effect on crc by synergistically inhibiting the dna damage repair pathway and activating the tumor cell apoptosis process without obvious toxicity. |
2023-10-30 |
2023-11-08 |
Not clear |
| Xu-Wang Pan, Jin-Song Huang, Shou-Rong Liu, Yi-Dan Shao, Jian-Jun Xi, Ruo-Yu He, Ting-Ting Shi, Rang-Xiao Zhuang, Jian-Feng Ba. Evaluation of the liver targeting and anti‑liver cancer activity of artesunate‑loaded and glycyrrhetinic acid‑coated nanoparticles. Experimental and therapeutic medicine. vol 26. issue 5. 2023-10-20. PMID:37854499. |
additionally, art/ga-peg-plga nps induced internal apoptosis pathways by upregulating the activity of cleaved caspase-3/7 and expression of cleaved poly (adp-ribose)-polymerase and phos-p38 mitogen-activated protein kinase in hepg2 cells. |
2023-10-20 |
2023-11-08 |
Not clear |
| Sanjib Das, Moumita Saha, Lokesh Chandra Mahata, Arya China, Niloy Chatterjee, Krishna Das Sah. Quercetin and 5-Fu Loaded Chitosan Nanoparticles Trigger Cell-Cycle Arrest and Induce Apoptosis in HCT116 Cells via Modulation of the p53/p21 Axis. ACS omega. vol 8. issue 40. 2023-10-16. PMID:37841142. |
cells were treated with cs-5-fu-qct nps and incubated for 12, 24, and 36 h, and apoptosis analysis (using annexin v/fitc), cell-cycle analysis, western blotting, and confocal microscopic analysis were performed. |
2023-10-16 |
2023-11-08 |
Not clear |
| Domenica Giannandrea, Marco Parolini, Valentina Citro, Beatrice De Felice, Alex Pezzotta, Nazanin Abazari, Natalia Platonova, Michela Sugni, Martina Chiu, Alessandro Villa, Elena Lesma, Raffaella Chiaramonte, Lavinia Casat. Nanoplastic impact on bone microenvironment: A snapshot from murine bone cells. Journal of hazardous materials. vol 462. 2023-10-11. PMID:37820528. |
nps affect cell viability and induce ros production and apoptosis (by caspase 3/7 activation) in pre-osteoblasts, osteocytes, and pre-osteoclasts. |
2023-10-11 |
2023-10-15 |
human |
| Sarvenaz Kashefi, Samira Mohammadi-Yeganeh, Fatemeh Ghorbani-Bidkorpeh, Mahdi Shabani, Ameneh Koochaki, Mehrnoush Safarzadeh, Mostafa Haji Molla Hosein. Anti-cancer effects of a chitosan based nanoformulation expressing miR-340 on 4T1 breast cancer cells. Journal of pharmaceutical sciences. 2023-10-08. PMID:37806438. |
furthermore, nps demonstrated appropriate transfection efficiency and could induce apoptosis, so had toxicity in 4t1 bc cells. |
2023-10-08 |
2023-10-15 |
Not clear |
| Shushan Zhang, Yongquan Huang, Songying Pi, Hui Chen, Feile Ye, Chaoqun Wu, Liujun Li, Qing Ye, Yuhong Lin, Zhongzhen S. Autophagy-amplifying nanoparticles evoke immunogenic cell death combined with anti-PD-1/PD-L1 for residual tumors immunotherapy after RFA. Journal of nanobiotechnology. vol 21. issue 1. 2023-10-03. PMID:37789342. |
we found that szp nps inhibited proliferation and stimulated apoptosis of residual tumor cells exposed to sublethal heat stress in an autophagy-dependent manner. |
2023-10-03 |
2023-10-07 |
Not clear |
| Heping Qiu, Jianwu Wang, Yi Zhi, Benhuang Yan, Yuandi Huang, Jinjin Li, Chongxing Shen, Linyong Dai, Qiang Fang, Chunmeng Shi, Weibing L. Hyaluronic Acid-Conjugated Fluorescent Probe-Shielded Polydopamine Nanomedicines for Targeted Imaging and Chemotherapy of Bladder Cancer. ACS applied materials & interfaces. 2023-09-28. PMID:37769147. |
encouragingly, intravesical instillation of hr-pdd nps improved drug retention in the bladder and promoted its accumulation in tumor tissue, resulting in better tumor proliferation inhibition and apoptosis in an orthotopic bladder cancer model in rats. |
2023-09-28 |
2023-10-07 |
rat |