| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junyan Chen, Kaidi Chen, Shuai Xue, Xiao Cheng, Yuwei Qi, Hangjie Wang, Wei Li, Guilin Cheng, Yang Xiong, Chaofeng Mu, Mancang G. Integration of caveolin-mediated cytosolic delivery and enzyme-responsive releasing of squalenoyl nanoparticles enhance the anti-cancer efficacy of chidamide in pancreatic cancer. International journal of pharmaceutics. 2024-04-01. PMID:38561133. |
following intraperitoneal administration to subcutaneous tumor-bearing nude mice, the a-c nps group demonstrated significant anti-pancreatic cancer efficacy, inducing cancer cell apoptosis and inhibiting proliferation in vivo. |
2024-04-01 |
2024-04-04 |
mouse |
| Qianqian Li, Maolin Tang, Shisheng Zhao, Junjie Yang, Yuanlin Meng, Chunmei Meng, Ling Ren, Weimin H. SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation. Discover. Oncology. vol 15. issue 1. 2024-03-06. PMID:38446289. |
saa1-overexpressing or saa1-knockdown escc cells were used to assess the effects of saa1 on the proliferation, migration, apoptosis of cancer cells and the growth of xenograft tumors in nude mice. |
2024-03-06 |
2024-03-08 |
mouse |
| Retraction: miR-34 inhibits growth and promotes apoptosis of osteosarcoma in nude mice through targetly regulating TGIF2 expression. Bioscience reports. vol 44. issue 2. 2024-02-28. PMID:38414402. |
retraction: mir-34 inhibits growth and promotes apoptosis of osteosarcoma in nude mice through targetly regulating tgif2 expression. |
2024-02-28 |
2024-03-01 |
mouse |
| Wang Chen, Pida Hao, Qile Song, Xiaotong Feng, Xuan Zhao, Jincheng Wu, Zixiang Gong, Jinli Zhang, Xiaoyan Fu, Xianjun Wan. Methylseleninic acid inhibits human glioma growth in vitro and in vivo by triggering ROS-dependent oxidative damage and apoptosis. Metabolic brain disease. 2024-02-28. PMID:38416338. |
importantly, mese administration in nude mice significantly inhibited glioma growth in vivo by inducing apoptosis through triggering oxidative damage. |
2024-02-28 |
2024-03-01 |
mouse |
| A A Kozlov, Yu O Sokolova, A L Kovalenko, E D Bazhanov. Effect of Lysine Acridone Acetate on the Level of Apoptosis and Expression of Apoptosis-Associated Proteins during Antioncogenic Therapy in Colorectal Cancer in Mice. Bulletin of experimental biology and medicine. 2024-01-09. PMID:38194065. |
in nude mouse model, the level of apoptosis (tunel) and expression of proteins cd95, p53, bcl-2, histone h3, and ki-67 (immunohistochemistry) were assessed in primary tumor biopsy specimens. |
2024-01-09 |
2024-01-10 |
mouse |
| Laura Soumoy, Aline Genbauffe, Lena Mouchart, Alexandra Sperone, Anne Trelcat, Léa Mukeba-Harchies, Mathilde Wells, Bertrand Blankert, Ahmad Najem, Ghanem Ghanem, Sven Saussez, Fabrice Journ. ATP1A1 is a promising new target for melanoma treatment and can be inhibited by its physiological ligand bufalin to restore targeted therapy efficacy. Cancer cell international. vol 24. issue 1. 2024-01-04. PMID:38178183. |
in vitro, bufalin induced apoptosis in melanoma cell lines by acting on atp1a1 (sirna experiments) and, in vivo, significantly impeded melanoma growth using a nude mouse xenograft model with continuous bufalin delivery via an osmotic pump. |
2024-01-04 |
2024-01-07 |
mouse |
| Chen Wang, Zhao-Yang Cui, Hai-Yan Chang, Chang-Zhen Wu, Zhao-Yan Yu, Xiao-Ting Wang, Yi-Qing Liu, Chang-Le Li, Xiang-Ge Du, Jian-Feng L. 2-Bromopalmitate inhibits malignant behaviors of HPSCC cells by hindering the membrane location of Ras protein. Experimental biology and medicine (Maywood, N.J.). 2023-12-30. PMID:38159074. |
subsequently, we investigated the effect of 2-bromopalmitate (2bp), a small-molecular inhibitor of protein palmitoylation, on the behavior of fadu cells in vitro (50 μm) and in nude mouse xenograft models (50 μmol/kg), and found that 2bp suppressed the proliferation, invasion, and migration of fadu cells without increasing cell apoptosis. |
2023-12-30 |
2024-01-05 |
mouse |
| Li Liu, Ke Gu, Dong Hu. HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1α/VEGF signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-11-28. PMID:38015530. |
in vivo, we found that hdac1 silence hindered tumor growth and cell proliferation and promoted tumor cell apoptosis in nude mice after radiotherapy. |
2023-11-28 |
2023-11-29 |
mouse |
| Luting Yu, Yihan Zhou, Shaozheng Sun, Runlin Wang, Weihong Yu, Hanyu Xiao, Zhuxi Yu, Chen Lu. Tumor-suppressive effect of Reg3A in COAD is mediated by T cell activation in nude mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 169. 2023-11-27. PMID:38011786. |
in the xenograft nude mice, reg3a overexpression offered a tumor-suppressive effect by inhibiting cell proliferation and promoting apoptosis. |
2023-11-27 |
2023-11-29 |
mouse |
| Wen Sun, Xiaoyu Ma, Yunxia Wang, Guosheng Yang, Jiping Liao, Yuan Cheng, Guangfa Wan. Light dose effect of photodynamic therapy on growth inhibition and apoptosis induction in non-small cell lung cancer: a study in nude mouse model. Photodiagnosis and photodynamic therapy. 2023-11-10. PMID:37949389. |
light dose effect of photodynamic therapy on growth inhibition and apoptosis induction in non-small cell lung cancer: a study in nude mouse model. |
2023-11-10 |
2023-11-20 |
mouse |
| Zhen Liu, Hong Zhang, Xiaoxia H. Analysis of the expression and mechanism of follistatin‑like protein 1 in cervical cancer. Oncology reports. vol 50. issue 6. 2023-10-27. PMID:37888756. |
the effects of abnormal expression of fstl1 on cervical cancer cells were assessed using colony formation, mtt, wound‑healing, transwell, apoptosis, and nude mouse tumorigenicity assays. |
2023-10-27 |
2023-11-08 |
mouse |
| Tong Wu, Qi Tian, Ruiji Liu, Ke Xu, Shanshan Shi, Xiudi Zhang, Liming Gao, Xiaobo Yin, Shufeng Xu, Ping Wan. Inhibitory role of bone marrow mesenchymal stem cells-derived exosome in non-small-cell lung cancer: microRNA-30b-5p, EZH2 and PI3K/AKT pathway. Journal of cellular and molecular medicine. 2023-09-12. PMID:37698037. |
animal experiments validated that bmsc-exo-mir-30b-5p promoted nsclc cell apoptosis and prevented tumorigenesis in nude mice via ezh2/pi3k/akt axis. |
2023-09-12 |
2023-10-07 |
mouse |
| Wangjian Li, Dongzhang Li, Quan Ma, Yongliang Chen, Zujian Hu, Yongheng Bai, Liping Xi. Targeted inhibition of mTOR by BML-275 induces mitochondrial-mediated apoptosis and autophagy in prostate cancer. European journal of pharmacology. 2023-09-01. PMID:37657741. |
nude mouse tumorigenic experiments also confirmed that bml-275 inhibited pca growth, induced pca cell apoptosis and autophagy. |
2023-09-01 |
2023-09-07 |
mouse |
| Huiping Chen, Yamei Li, Yixian Liu, Ying Zhao, Fang Xu, Shuangshuang Yang, Mengdan Yu, Min Zou, Jintao Zhan. Epinodosin suppresses the proliferation, invasion, and migration of esophageal squamous cell carcinoma by mediating miRNA-143-3p/Bcl-2 axis. Phytotherapy research : PTR. 2023-08-17. PMID:37589332. |
in conclusion, epinodosin suppresses cell viability/invasion/migration, while induces escc cell apoptosis by mediating mirna-143-3p and bcl-2, and can markedly attenuate the growth of escc tumors in nude mice. |
2023-08-17 |
2023-09-07 |
mouse |
| Jiayang Yin, Feng Zhang, Jiamin Cao, Zhaochangci Chen, Wei Xion. Gentiopicroside inhibits retinoblastoma cell proliferation, invasion, and tumorigenesis in nude mice by suppressing the PI3K/AKT pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2023-08-09. PMID:37555853. |
this study sought to determine the effect of gps on retinoblastoma cell proliferation, apoptosis, invasion, and epithelial-mesenchymal transition (emt), and tumorigenesis in nude mice. |
2023-08-09 |
2023-08-16 |
mouse |
| Xiao-Cui Chen, Li-Feng Huang, Ji-Xin Tang, Dan Wu, Ning An, Zhen-Nan Ye, Hui-Yao Lan, Hua-Feng Liu, Chen Yan. Asiatic acid alleviates cisplatin-induced renal fibrosis in tumor-bearing mice by improving the TFEB-mediated autophagy-lysosome pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-07-06. PMID:37413899. |
in addition, aa treatment did not weaken, but actually enhanced the anti-tumor effect of cisplatin, as evidenced by the promoted tumor apoptosis and inhibited proliferation in nude mice. |
2023-07-06 |
2023-08-14 |
mouse |
| Yudi Ma, Xiaohui Lai, Zhongling Wen, Ziling Zhou, Minkai Yang, Qingqing Chen, Xuan Wang, Feng Mei, Liu Yang, Tongming Yin, Shucun Sun, Guihua Lu, Jinliang Qi, Hongyan Lin, Hongwei Han, Yonghua Yan. Design, synthesis and biological evaluation of novel modified dual-target shikonin derivatives for colorectal cancer treatment. Bioorganic chemistry. vol 139. 2023-07-03. PMID:37399615. |
finally, the in vivo anti-tumor activity of z10 was evaluated in a colorectal cancer cell xenograft model in nude mice and the results demonstrated that z10 induced tumor cell apoptosis and inhibited tumor cell proliferation with lower toxicity than shikonin. |
2023-07-03 |
2023-08-14 |
mouse |
| Yun Zhou, Tongyu Liu, Qiaoling Wu, Huihui Wang, Yang Su. Baohuoside I inhibits resistance to cisplatin in ovarian cancer cells by suppressing autophagy via downregulating HIF-1α/ATG5 axis. Molecular carcinogenesis. 2023-06-07. PMID:37283234. |
additionally, evaluation of baohuoside i's role in ovarian cancer was performed using a nude mouse xenograft model. baohuoside i decreased the viability and proliferation and triggered the apoptosis of both a2780 and a2780/ddp cells in a concentration-dependent manner. |
2023-06-07 |
2023-08-14 |
mouse |
| Cheng Huang, Zi-Jun Lin, Jui-Chieh Chen, Hao-Jun Zheng, Yu-Heng Lai, Hsiu-Chen Huan. α-Viniferin-Induced Apoptosis through Downregulation of SIRT1 in Non-Small Cell Lung Cancer Cells. Pharmaceuticals (Basel, Switzerland). vol 16. issue 5. 2023-05-27. PMID:37242510. |
as demonstrated by the tunel assay results, α-viniferin promoted apoptosis in nci-h460 cells in nude mice. |
2023-05-27 |
2023-08-14 |
mouse |
| Guang Yang, Yunbiao He, Yingxing Chen, Zhihan Huang, Jieqiong Huang, Xinyi Ren, Shihai Xu, Ping L. Antitumor activity of galaxamide involved in cell apoptosis and stemness by inhibiting Wnt/β-catenin pathway in cervical cancer. Drug development research. 2023-05-08. PMID:37154105. |
galaxamide treatment was also accompanied by the induction of apoptosis in hela cells, which was consistent with the results in balb/c nude mice. |
2023-05-08 |
2023-08-14 |
mouse |