Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
L Ji, B Fang, N Yen, K Fong, J D Minna, J A Rot. Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression. Cancer research. vol 59. issue 14. 1999-08-12. PMID:10416589. |
we studied the effects of fragile histidine triad (fhit) gene overexpression mediated by an adenoviral vector, ad-fhit, on cell proliferation, apoptosis, and cell cycle kinetics in human cancer cells and on tumorigenicity and tumor growth in nude mice. |
1999-08-12 |
2023-08-12 |
mouse |
S M Janicki, M J Monteir. Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant. The American journal of pathology. vol 155. issue 1. 1999-07-26. PMID:10393846. |
to investigate the mechanism by which presenilin (ps) overexpression induces apoptosis, we studied the effects of these proteins on cell cycle progression. |
1999-07-26 |
2023-08-12 |
Not clear |
L Gollapudi, M M Oblinge. Estrogen and NGF synergistically protect terminally differentiated, ERalpha-transfected PC12 cells from apoptosis. Journal of neuroscience research. vol 56. issue 5. 1999-07-23. PMID:10369214. |
we challenged differentiated pcer and pccon cells with serum-free media and assessed the effects of various treatments on cell survival and apoptosis using trypan blue staining and quantitative tunel staining. |
1999-07-23 |
2023-08-12 |
rat |
M Buemi, A Allegra, M Senatore, D Marino, M A Medici, C Aloisi, G Di Pasquale, F Coric. Pro-apoptotic effect of fluvastatin on human smooth muscle cells. European journal of pharmacology. vol 370. issue 2. 1999-07-16. PMID:10323270. |
we therefore evaluated the effect, in vitro, of the addition of the serum of patients taking fluvastatin on human smooth muscle cells in order to ascertain the effect of the drug on cell proliferation and apoptosis. |
1999-07-16 |
2023-08-12 |
human |
J M Daly, M A Olayioye, A M Wong, R Neve, H A Lane, F G Maurer, N E Hyne. NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: role of PI3 kinase and p38 MAP kinase pathways. Oncogene. vol 18. issue 23. 1999-06-30. PMID:10376522. |
inhibition of erk1/erk2 had no effect on cell cycle progression or apoptosis. |
1999-06-30 |
2023-08-12 |
Not clear |
F Burke, P D Smith, M R Crompton, C Upton, F R Balkwil. Cytotoxic response of ovarian cancer cell lines to IFN-gamma is associated with sustained induction of IRF-1 and p21 mRNA. British journal of cancer. vol 80. issue 8. 1999-06-30. PMID:10376977. |
continuous exposure to ifn-gamma for 2-3 days was necessary for an irreversible effect on cell growth and apoptosis in cells sensitive to growth inhibition. |
1999-06-30 |
2023-08-12 |
human |
C M Lee, E P Redd. The v-myc oncogene. Oncogene. vol 18. issue 19. 1999-06-25. PMID:10378695. |
recent developments on the effects of v-myc on cell growth, transformation, differentiation and apoptosis are discussed in this review. |
1999-06-25 |
2023-08-12 |
Not clear |
M Ono, K Handa, D A Withers, S Hakomor. Motility inhibition and apoptosis are induced by metastasis-suppressing gene product CD82 and its analogue CD9, with concurrent glycosylation. Cancer research. vol 59. issue 10. 1999-06-17. PMID:10344740. |
thus, the malignancy-suppressing effect of cd82 or cd9 is based partially on cell motility inhibition and apoptosis induction promoted by concurrent gm3 synthesis and n-glycosylation. |
1999-06-17 |
2023-08-12 |
human |
B A Narayanan, O Geoffroy, M C Willingham, G G Re, D W Nixo. p53/p21(WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer letters. vol 136. issue 2. 1999-06-17. PMID:10355751. |
the effects of ellagic acid on cell cycle events and apoptosis were studied in cervical carcinoma (caski) cells. |
1999-06-17 |
2023-08-12 |
Not clear |
M Koutsilieris, C Reyes-Moreno, I Choki, A Sourla, C Doillon, N Pavlidi. Chemotherapy cytotoxicity of human MCF-7 and MDA-MB 231 breast cancer cells is altered by osteoblast-derived growth factors. Molecular medicine (Cambridge, Mass.). vol 5. issue 2. 1999-06-11. PMID:10203574. |
therefore, we analyzed the ability of human mg-63 osteoblast-like cells (mg-63 cells), mg-63 conditioned media (mg-63 cm), insulin-like growth factor i (igf-i), and transforming growth factor beta 1 (tgf-beta1) to alter the effects of adriamycin on cell cycle and apoptosis of estrogen receptor negative (er-) mda-mb-231 and positive (er+) mcf-7 breast cancer cells, using cell count, trypan blue exclusion, flow cytometry, detection of dna fragmentation by simple agarose gel, and the terminal deoxynucleotidyl transferase (tdt)-mediated nick end-labeling method for apoptosis (tunel assay). |
1999-06-11 |
2023-08-12 |
human |
G S Wang, L C Eriksson, L Xia, J Olsson, P Stå. Dietary iron overload inhibits carbon tetrachloride-induced promotion in chemical hepatocarcinogenesis: effects on cell proliferation, apoptosis, and antioxidation. Journal of hepatology. vol 30. issue 4. 1999-06-07. PMID:10207812. |
dietary iron overload inhibits carbon tetrachloride-induced promotion in chemical hepatocarcinogenesis: effects on cell proliferation, apoptosis, and antioxidation. |
1999-06-07 |
2023-08-12 |
Not clear |
B Li, M Setoguchi, X Wang, A M Andreoli, A Leri, A Malhotra, J Kajstura, P Anvers. Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circulation research. vol 84. issue 9. 1999-06-03. PMID:10325238. |
constitutive overexpression of igf-1 attenuates myocyte necrosis and tissue injury, having no effect on cell apoptosis. |
1999-06-03 |
2023-08-12 |
mouse |
C Fiorentini, M Gauthier, G Donelli, P Boque. Bacterial toxins and the Rho GTP-binding protein: what microbes teach us about cell regulation. Cell death and differentiation. vol 5. issue 9. 1999-05-28. PMID:10200530. |
c3 and cnf1 have opposite effects on rho thus representing useful tools for studies on cell division, cell differentiation and apoptosis. |
1999-05-28 |
2023-08-12 |
Not clear |
C Fimognari, M Nüsse, P Hreli. Flow cytometric analysis of genetic damage, effect on cell cycle progression, and apoptosis by thiophanate-methyl in human lymphocytes. Environmental and molecular mutagenesis. vol 33. issue 2. 1999-05-06. PMID:10217072. |
flow cytometric analysis of genetic damage, effect on cell cycle progression, and apoptosis by thiophanate-methyl in human lymphocytes. |
1999-05-06 |
2023-08-12 |
human |
C Fimognari, M Nüsse, P Hreli. Flow cytometric analysis of genetic damage, effect on cell cycle progression, and apoptosis by thiophanate-methyl in human lymphocytes. Environmental and molecular mutagenesis. vol 33. issue 2. 1999-05-06. PMID:10217072. |
flow cytometric technique was used to study the effects of the fungicide thiophanate-methyl on cell proliferation, micronucleus induction, and apoptosis in human peripheral blood lymphocytes treated in vitro. |
1999-05-06 |
2023-08-12 |
human |
S Teramoto, T Tomita, H Matsui, E Ohga, T Matsuse, Y Ouch. Hydrogen peroxide-induced apoptosis and necrosis in human lung fibroblasts: protective roles of glutathione. Japanese journal of pharmacology. vol 79. issue 1. 1999-05-04. PMID:10082315. |
we therefore examined the effects of hydrogen peroxide (h2o2) on cell growth kinetics in human lung fibroblasts (hfl-1 cells) and tested the roles of antioxidants on the h2o2-induced cell death (i.e., necrosis and apoptosis) in hfl-1 cells. |
1999-05-04 |
2023-08-12 |
human |
S T Huang, J A Cidlowsk. Glucocorticoids inhibit serum depletion-induced apoptosis in T lymphocytes expressing Bcl-2. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 3. 1999-04-07. PMID:10064613. |
bcl-2 expression abrogated the repressive effect of glucocorticoids on apoptosis but not on cell growth. |
1999-04-07 |
2023-08-12 |
Not clear |
C D Albright, A Y Tsai, C B Friedrich, M H Mar, S H Zeise. Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain research. Developmental brain research. vol 113. issue 1-2. 1999-04-07. PMID:10064869. |
in the present study, the effects of dietary choline on cell proliferation, migration, and apoptosis in neuronal progenitor cells in the hippocampus and septum were analyzed in fetal brains at different stages of embryonic development. |
1999-04-07 |
2023-08-12 |
rat |
R Linden, S K Rehen, L B Chiarin. Apoptosis in developing retinal tissue. Progress in retinal and eye research. vol 18. issue 2. 1999-03-22. PMID:9932281. |
we found that various characteristics of apoptosis are selectively associated with retinal cell death depending on cell type, stage of maturation, and means of induction of apoptosis. |
1999-03-22 |
2023-08-12 |
Not clear |
A Håkansson, J Andréasson, B Zhivotovsky, D Karpman, S Orrenius, C Svanbor. Multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei. Experimental cell research. vol 246. issue 2. 1999-03-15. PMID:9925761. |
multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei. |
1999-03-15 |
2023-08-12 |
human |