| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Thase, R H Howland, E S Friedma. Treating antidepressant nonresponders with augmentation strategies: an overview. The Journal of clinical psychiatry. vol 59 Suppl 5. 1998-06-24. PMID:9635543. |
when effective, the more widely used augmentation strategies, including lithium salts, thyroid hormones, pindolol, buspirone, and psychostimulants, share two important advantages when compared with "switching" strategies: avoidance of ill effects associated with discontinuing the initial antidepressant and rapidity of onset of action. |
1998-06-24 |
2023-08-12 |
Not clear |
| C López-Rubalcav. Pre- or postsynaptic activity of 5-HT1A compounds in mice depends on the anxiety paradigm. Pharmacology, biochemistry, and behavior. vol 54. issue 4. 1997-01-06. PMID:8853189. |
to this aim, the 5-ht1a ligands buspirone, ipsapirone, indorenate, and 8-oh-dpat were tested in the burying behavior test and the avoidance exploratory behavior paradigm in control, pcpa-treated, and 5,7-dht-lesioned mice, p-cpa and 5,7-dht treatments did not modify the burying behavior per se, while 5-ht1a agonists produced a significant reduction in this behavior in both p-cpa- and 5,7,-dht-lesioned animals. |
1997-01-06 |
2023-08-12 |
mouse |
| C Torres, A Morales, A Cándido, A Maldonad. Differential effect of buspirone and diazepam on negative contrast in one-way avoidance learning. European journal of pharmacology. vol 280. issue 3. 1996-03-07. PMID:8566095. |
the highest dose of buspirone used, however, did interfere with the learning of the avoidance response itself. |
1996-03-07 |
2023-08-12 |
rat |
| K Ensler, C N Ryan, J L Evende. Effects of repeated treatment with 5-HT1A agonists on active avoidance responding in the rat. Psychopharmacology. vol 112. issue 1. 1995-03-29. PMID:7871009. |
buspirone, the 5-ht1a partial agonist/dopamine d2 antagonist, markedly decreased activity, and thus avoidance of the shocks, in a manner similar to the antipsychotic drug, haloperidol. |
1995-03-29 |
2023-08-12 |
rat |
| D Quartermain, J Clemente, A Sheme. The 5-HT1A agonist tandospirone disrupts retention but not acquisition of active avoidance learning. Pharmacology, biochemistry, and behavior. vol 48. issue 3. 1994-11-04. PMID:7938139. |
to determine the effects of the 5-ht1a partial agonist tandospirone on acquisition and retention, mice were trained on a one-way active avoidance task and tested for retention 24 h later. |
1994-11-04 |
2023-08-12 |
mouse |
| D Quartermain, J Clemente, A Sheme. The 5-HT1A agonist tandospirone disrupts retention but not acquisition of active avoidance learning. Pharmacology, biochemistry, and behavior. vol 48. issue 3. 1994-11-04. PMID:7938139. |
results showed that tandospirone did not alter the rate of acquisition of the avoidance response, but retention was significantly disrupted by the 1- and 5-mg/kg doses. |
1994-11-04 |
2023-08-12 |
mouse |
| W K Cullen, M J Rowa. Gepirone and 1-(2-pyrimidinyl)-piperazine-induced reduction of aversively evoked ultrasonic vocalisation in the rat. Pharmacology, biochemistry, and behavior. vol 48. issue 1. 1994-08-10. PMID:7913229. |
performance of a 24 h step-through passive avoidance task was impaired by gepirone only at a dose, 5 mg/kg, which also reduced spontaneous locomotor and rearing activity in the apparatus. |
1994-08-10 |
2023-08-12 |
rat |
| W K Cullen, M J Rowa. Gepirone and 1-(2-pyrimidinyl)-piperazine-induced reduction of aversively evoked ultrasonic vocalisation in the rat. Pharmacology, biochemistry, and behavior. vol 48. issue 1. 1994-08-10. PMID:7913229. |
it would appear that mild foot shock-evoked ultrasonic vocalisation may provide a more sensitive indicator of the effect of gepirone and related drugs on the affective response of rats to aversive stimulation. |
1994-08-10 |
2023-08-12 |
rat |
| A A Alhaider, A M Ageel, O T Ginaw. The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors. Neuropharmacology. vol 32. issue 12. 1994-05-10. PMID:8152532. |
the 5-ht1a agonist, buspirone, significantly decreased acquisition of conditioned avoidance. |
1994-05-10 |
2023-08-12 |
rat |
| S D Mendelson, D Quartermain, T Francisco, A Sheme. 5-HT1A receptor agonists induce anterograde amnesia in mice through a postsynaptic mechanism. European journal of pharmacology. vol 236. issue 2. 1993-08-05. PMID:8319749. |
the effect of the 5-ht1a receptor partial agonist tandospirone on memory was investigated in mice using a single trial, step-through passive avoidance task. |
1993-08-05 |
2023-08-12 |
mouse |
| B Costall, A M Domeney, A J Farre, M E Kelly, L Martinez, R J Naylo. Profile of action of a novel 5-hydroxytryptamine1A receptor ligand E-4424 to inhibit aversive behavior in the mouse, rat and marmoset. The Journal of pharmacology and experimental therapeutics. vol 262. issue 1. 1992-08-11. PMID:1352556. |
e-4424 was compared to diazepam, buspirone and ipsapirone to inhibit the behavioral response to an aversive situation in the mouse black and white test box, the rat social interaction test and a marmoset human threat test. |
1992-08-11 |
2023-08-11 |
mouse |
| T Wada, N Fukud. Effect of a new anxiolytic, DN-2327, on learning and memory in rats. Pharmacology, biochemistry, and behavior. vol 41. issue 3. 1992-06-18. PMID:1350101. |
the effects of a new anxiolytic, (2-(7-chloro-1,8-naphthyridin-2-yl)-3- [(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-carbonylmethyl] isoindolin-1-one (dn-2327), on the execution of step-through passive avoidance and delayed spontaneous alternation tasks were assessed and compared with those of diazepam (dzp) and buspirone. |
1992-06-18 |
2023-08-11 |
rat |
| T Wada, N Fukud. Effect of a new anxiolytic, DN-2327, on learning and memory in rats. Pharmacology, biochemistry, and behavior. vol 41. issue 3. 1992-06-18. PMID:1350101. |
dn-2327 and buspirone (both 10 and 20 mg/kg, po) impaired performance in the 48-h passive avoidance recall test when given prior to the test session, but not when given before the training trial. |
1992-06-18 |
2023-08-11 |
rat |
| N M Barnes, B Costall, A M Domeney, P A Gerrard, M E Kelly, H Krähling, R J Naylor, D M Tomkins, T J William. The effects of umespirone as a potential anxiolytic and antipsychotic agent. Pharmacology, biochemistry, and behavior. vol 40. issue 1. 1992-03-10. PMID:1685786. |
in the mouse black and white test box, umespirone was considerably more potent than diazepam or buspirone to reduce aversive responding, tolerance to its effects was not observed and sedation was absent, a chronic treatment and withdrawal was not associated with an anxiogenic profile, and umespirone prevented the behavioural consequences of withdrawal from diazepam. |
1992-03-10 |
2023-08-11 |
mouse |
| D Treit, K C Berridg. A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm. Pharmacology, biochemistry, and behavior. vol 37. issue 3. 1991-05-23. PMID:1982355. |
the putative 5-ht1a agonists, buspirone and gepirone, had a general inhibitory action on both positive and aversive palatability reactions. |
1991-05-23 |
2023-08-11 |
rat |
| M Galizio, J W Journey, S A Royal, J A Welke. Variable-interval schedules of timeout from avoidance: effects of anxiolytic and antipsychotic drugs in rats. Pharmacology, biochemistry, and behavior. vol 37. issue 2. 1991-04-26. PMID:1981935. |
like chlorpromazine, buspirone decreased both avoidance and timeout responding. |
1991-04-26 |
2023-08-11 |
rat |
| J L Neisewander, S A McDougall, S L Bowling, M T Bard. Conditioned taste aversion and place preference with buspirone and gepirone. Psychopharmacology. vol 100. issue 4. 1990-04-30. PMID:2320709. |
conditioned taste aversion and place preference with buspirone and gepirone. |
1990-04-30 |
2023-08-11 |
Not clear |
| J L Neisewander, S A McDougall, S L Bowling, M T Bard. Conditioned taste aversion and place preference with buspirone and gepirone. Psychopharmacology. vol 100. issue 4. 1990-04-30. PMID:2320709. |
the effects of the nonbenzodiazepine anxiolytics buspirone and gepirone were compared to diazepam at 1, 3, and 10 mg/kg using the conditioned taste aversion (cta) paradigm. |
1990-04-30 |
2023-08-11 |
Not clear |
| J L Neisewander, S A McDougall, S L Bowling, M T Bard. Conditioned taste aversion and place preference with buspirone and gepirone. Psychopharmacology. vol 100. issue 4. 1990-04-30. PMID:2320709. |
buspirone and gepirone produced stronger cta than diazepam (3 and 10 mg/kg) across repeated conditioning trials, indicating that these nonbenzodiazepine anxiolytics may have stronger aversive properties than diazepam. |
1990-04-30 |
2023-08-11 |
Not clear |
| M J Rowan, W K Cullen, B Moulto. Buspirone impairment of performance of passive avoidance and spatial learning tasks in the rat. Psychopharmacology. vol 100. issue 3. 1990-04-17. PMID:2315436. |
buspirone impairment of performance of passive avoidance and spatial learning tasks in the rat. |
1990-04-17 |
2023-08-11 |
rat |