| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Bálentová, M Adamko. Pathological changes in the central nervous system following exposure to ionizing radiation. Physiological research. vol 69. issue 3. 2021-06-03. PMID:32469226. |
most recent findings in cranial radiotherapy revealed that hippocampal avoidance prevents radiation-induced cognitive impairment of patients with brain primary tumors and metastases. |
2021-06-03 |
2023-08-13 |
Not clear |
| Joyce Mendes-Gomes, Simone Cristina Motta, Ricardo Passoni Bindi, Amanda Ribeiro de Oliveira, Farhad Ullah, Marcus Vinicius C Baldo, Norberto Cysne Coimbra, Newton Sabino Canteras, D Caroline Blanchar. Defensive behaviors and brain regional activation changes in rats confronting a snake. Behavioural brain research. vol 381. 2021-05-26. PMID:31917239. |
in addition, the juxtodorsalmedial region of the lateral hypothalamus showed enhanced fos activation, where inputs from the septo-hippocampal system may suggest the potential involvement of hippocampal boundary cells in the very strong spatial avoidance of the snake and the area it occupied. |
2021-05-26 |
2023-08-13 |
human |
| José S A Belderbos, Dirk K M De Ruysscher, Katrien De Jaeger, Friederike Koppe, Maarten L F Lambrecht, Yolande N Lievens, Edith M T Dieleman, Jaap P M Jaspers, Jan P Van Meerbeeck, Fred Ubbels, Margriet H Kwint, Marianne A Kuenen, Sabine Deprez, Michiel B De Ruiter, Willem Boogerd, Karolina Sikorska, Harm Van Tinteren, Sanne B Schage. Phase 3 Randomized Trial of Prophylactic Cranial Irradiation With or Without Hippocampus Avoidance in SCLC (NCT01780675). Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. vol 16. issue 5. 2021-05-24. PMID:33545387. |
phase 3 randomized trial of prophylactic cranial irradiation with or without hippocampus avoidance in sclc (nct01780675). |
2021-05-24 |
2023-08-13 |
Not clear |
| José S A Belderbos, Dirk K M De Ruysscher, Katrien De Jaeger, Friederike Koppe, Maarten L F Lambrecht, Yolande N Lievens, Edith M T Dieleman, Jaap P M Jaspers, Jan P Van Meerbeeck, Fred Ubbels, Margriet H Kwint, Marianne A Kuenen, Sabine Deprez, Michiel B De Ruiter, Willem Boogerd, Karolina Sikorska, Harm Van Tinteren, Sanne B Schage. Phase 3 Randomized Trial of Prophylactic Cranial Irradiation With or Without Hippocampus Avoidance in SCLC (NCT01780675). Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. vol 16. issue 5. 2021-05-24. PMID:33545387. |
to compare neurocognitive functioning in patients with sclc who received prophylactic cranial irradiation (pci) with or without hippocampus avoidance (ha). |
2021-05-24 |
2023-08-13 |
Not clear |
| Fatemehsadat Seyedaghamiri, Fereshteh Farajdokht, Seyed Mehdi Vatandoust, Javad Mahmoudi, Aytak Khabbaz, Saeed Sadigh-Etegha. Sericin modulates learning and memory behaviors by tuning of antioxidant, inflammatory, and apoptotic markers in the hippocampus of aged mice. Molecular biology reports. vol 48. issue 2. 2021-05-18. PMID:33523373. |
this study aimed to examine the effects of sericin administration on episodic and avoidance memories, social interaction behavior, and molecular mechanisms including oxidative stress, inflammation, and apoptosis in the hippocampus of aged mice. |
2021-05-18 |
2023-08-13 |
mouse |
| Mohammad Abbas Sheikholeslami, Shiva Ghafghazi, Ramin Pouriran, Seyed Erfan Mortazavi, Siavash Parvarde. Attenuating effect of paroxetine on memory impairment following cerebral ischemia-reperfusion injury in rat: The involvement of BDNF and antioxidant capacity. European journal of pharmacology. vol 893. 2021-05-17. PMID:33347827. |
a week after ischemia-reperfusion injury, passive avoidance memory, long-term potentiation (ltp), bdnf levels, total antioxidant capacity, the activity of antioxidant enzymes (including catalase, glutathione peroxidase, and superoxide dismutase), the concentration of malondialdehyde (mda), and nitric oxide (no) were investigated in the hippocampus. |
2021-05-17 |
2023-08-13 |
rat |
| Mohammad Abbas Sheikholeslami, Shiva Ghafghazi, Ramin Pouriran, Seyed Erfan Mortazavi, Siavash Parvarde. Attenuating effect of paroxetine on memory impairment following cerebral ischemia-reperfusion injury in rat: The involvement of BDNF and antioxidant capacity. European journal of pharmacology. vol 893. 2021-05-17. PMID:33347827. |
this affirmative function of paroxetine on the passive avoidance memory was accompanied by the improvement of hippocampal ltp and an obvious augmentation in the bdnf contents. |
2021-05-17 |
2023-08-13 |
rat |
| Mohammad Abbas Sheikholeslami, Shiva Ghafghazi, Ramin Pouriran, Seyed Erfan Mortazavi, Siavash Parvarde. Attenuating effect of paroxetine on memory impairment following cerebral ischemia-reperfusion injury in rat: The involvement of BDNF and antioxidant capacity. European journal of pharmacology. vol 893. 2021-05-17. PMID:33347827. |
it was ultimately attained that paroxetine attenuates cerebral ischemia-induced passive avoidance memory dysfunction in rats by the enhancement of hippocampal synaptic plasticity and bdnf content together with the suppression of oxidative/nitrosative stress. |
2021-05-17 |
2023-08-13 |
rat |
| Manuela Simonetti, Eszter Paldy, Christian Njoo, Kiran Kumar Bali, Thomas Worzfeld, Claudia Pitzer, Thomas Kuner, Stefan Offermanns, Daniela Mauceri, Rohini Kune. The impact of Semaphorin 4C/Plexin-B2 signaling on fear memory via remodeling of neuronal and synaptic morphology. Molecular psychiatry. vol 26. issue 4. 2021-05-14. PMID:31444474. |
we observed that plexin-b2 and sema4c are expressed in forebrain areas related to fear memory, such as the anterior cingulate cortex, amygdala and the hippocampus, and their expression is regulated by aversive stimuli that induce fear memory. |
2021-05-14 |
2023-08-13 |
mouse |
| Evan Porter, Patricia Fuentes, Zaid Siddiqui, Andrew Thompson, Ronald Levitin, David Solis, Nick Myziuk, Thomas Guerrer. Hippocampus segmentation on noncontrast CT using deep learning. Medical physics. vol 47. issue 7. 2021-05-14. PMID:32065401. |
accurate segmentation of the hippocampus for hippocampal avoidance whole-brain radiotherapy currently requires high-resolution magnetic resonance imaging (mri) in addition to neuroanatomic expertise for manual segmentation. |
2021-05-14 |
2023-08-13 |
Not clear |
| Paw-Min-Thein-Oo, Yuya Sakimoto, Hiroyuki Kida, Dai Mitsushim. Proximodistal Heterogeneity in Learning-promoted Pathway-specific Plasticity at Dorsal CA1 Synapses. Neuroscience. vol 437. 2021-05-14. PMID:32360699. |
we subjected male rats to an inhibitory avoidance task and prepared acute hippocampal slices for whole-cell patch clamp experiments, where we stimulated eciii-ca1 or ca3-ca1 input fibers to analyze evoked excitatory postsynaptic currents (epscs). |
2021-05-14 |
2023-08-13 |
rat |
| Nae Saito, Kazuki Tainaka, Tom Macpherson, Takatoshi Hikida, Shun Yamaguchi, Toshikuni Sasaok. Neurotransmission through dopamine D1 receptors is required for aversive memory formation and Arc activation in the cerebral cortex. Neuroscience research. vol 156. 2021-05-14. PMID:32380131. |
we also performed whole-brain imaging after aversive footshock stimulation in activity-regulated cytoskeleton protein (arc)-dvenus d1rkd mice, which were crossbred from arc-dvenus transgenic mice and d1rkd mice, to examine the distribution of arc-controlled dvenus expression in the hippocampus and cerebral cortex during aversive memory formation. |
2021-05-14 |
2023-08-13 |
mouse |
| Nae Saito, Kazuki Tainaka, Tom Macpherson, Takatoshi Hikida, Shun Yamaguchi, Toshikuni Sasaok. Neurotransmission through dopamine D1 receptors is required for aversive memory formation and Arc activation in the cerebral cortex. Neuroscience research. vol 156. 2021-05-14. PMID:32380131. |
knockdown of d1r expression following dox treatment resulted in impaired performance in the passive avoidance test and was associated with a decrease in dvenus expression in the cerebral cortex (visual, somatosensory, and motor cortices), but not the hippocampus, compared with control mice without dox treatment. |
2021-05-14 |
2023-08-13 |
mouse |
| Julia C Bartsch, Monique von Cramon, David Gruber, Uwe Heinemann, Joachim Beh. Stress-Induced Enhanced Long-Term Potentiation and Reduced Threshold for N-Methyl-D-Aspartate Receptor- and β-Adrenergic Receptor-Mediated Synaptic Plasticity in Rodent Ventral Subiculum. Frontiers in molecular neuroscience. vol 14. 2021-05-13. PMID:33967694. |
therefore, we investigated the impact of a single exposure to an inherently stressful two-way active avoidance conditioning on the induction of long-term potentiation (ltp) at ca1-subiculum synapses in ventral hippocampal slices from young adult rats 1 day after stressor exposure. |
2021-05-13 |
2023-08-13 |
rat |
| Brendan Seng Hup Chia, Jing Yun Leong, Ashley Li Kuan Ong, Cindy Lim, Shi Hui Poon, Melvin Lee Kiang Chua, Kevin Lee Min Chua, Grace Kusumawidjaja, Eu Tiong Chua, Fuh Yong Wong, Tih Shih Le. Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol. BMC cancer. vol 20. issue 1. 2021-05-10. PMID:33126867. |
randomised prospective phase ii trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: ha-sib-wbrt study protocol. |
2021-05-10 |
2023-08-13 |
Not clear |
| Brendan Seng Hup Chia, Jing Yun Leong, Ashley Li Kuan Ong, Cindy Lim, Shi Hui Poon, Melvin Lee Kiang Chua, Kevin Lee Min Chua, Grace Kusumawidjaja, Eu Tiong Chua, Fuh Yong Wong, Tih Shih Le. Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol. BMC cancer. vol 20. issue 1. 2021-05-10. PMID:33126867. |
recent evidence supports hippocampal avoidance with whole brain radiotherapy (ha-wbrt) as the recommended treatment option in patients with good prognosis and multiple brain metastases as this results in better neurocognitive preservation compared to whole brain radiotherapy. |
2021-05-10 |
2023-08-13 |
Not clear |
| Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. |
the facilitating effect of mk-801 on inhibitory avoidance memory via mtor signaling in the mouse hippocampus. |
2021-05-06 |
2023-08-13 |
mouse |
| Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. |
in this study, we investigated the effect of mk-801 on multiple memory stages of the inhibitory avoidance task, as well as its underlying signaling mechanism in the mouse hippocampus. |
2021-05-06 |
2023-08-13 |
mouse |
| Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. |
these results indicate that hippocampal mtor signaling mediates the facilitating effect of mk-801 on memory consolidation of the inhibitory avoidance task. |
2021-05-06 |
2023-08-13 |
mouse |
| Kenneth D Westover, J Travis Mendel, Tu Dan, Kiran Kumar, Ang Gao, Suprabha Pulipparacharuv, Puneeth Iyengar, Lucien Nedzi, Raquibul Hannan, John Anderson, Kevin S Choe, Wen Jiang, Ramzi Abdulrahman, Asal Rahimi, Michael Folkert, Aaron Laine, Chase Presley, C Munro Cullum, Hak Choy, Chul Ahn, Robert Timmerma. Phase II trial of hippocampal-sparing whole brain irradiation with simultaneous integrated boost for metastatic cancer. Neuro-oncology. vol 22. issue 12. 2021-04-28. PMID:32347302. |
advanced radiotherapeutic treatment techniques limit the cognitive morbidity associated with whole-brain radiotherapy (wbrt) for brain metastasis through avoidance of hippocampal structures. |
2021-04-28 |
2023-08-13 |
Not clear |