| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul D Brown, Vinai Gondi, Stephanie Pugh, Wolfgang A Tome, Jeffrey S Wefel, Terri S Armstrong, Joseph A Bovi, Cliff Robinson, Andre Konski, Deepak Khuntia, David Grosshans, Tammie L S Benzinger, Deborah Bruner, Mark R Gilbert, David Roberge, Vijayananda Kundapur, Kiran Devisetty, Sunjay Shah, Kenneth Usuki, Bethany Marie Anderson, Baldassarre Stea, Harold Yoon, Jing Li, Nadia N Laack, Tim J Kruser, Steven J Chmura, Wenyin Shi, Snehal Deshmukh, Minesh P Mehta, Lisa A Kachni. Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. vol 38. issue 10. 2021-01-25. PMID:32058845. |
hippocampal avoidance (ha) using intensity-modulated radiotherapy during whole-brain radiotherapy (wbrt) is hypothesized to preserve cognition. |
2021-01-25 |
2023-08-13 |
Not clear |
| Joshua Stoker, Sujay Vora, Ameet Patel, David Grosshans, Paul D Brown, Tamara Vern-Gross, Martin Bues, Thomas Daniels, Bryce Allred, Arielle Uejo, Heidi Kosiorek, Marlene Bruso, Sameer Keol. Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy. Physics and imaging in radiation oncology. vol 8. 2021-01-19. PMID:33458413. |
advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy. |
2021-01-19 |
2023-08-13 |
Not clear |
| Joshua Stoker, Sujay Vora, Ameet Patel, David Grosshans, Paul D Brown, Tamara Vern-Gross, Martin Bues, Thomas Daniels, Bryce Allred, Arielle Uejo, Heidi Kosiorek, Marlene Bruso, Sameer Keol. Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy. Physics and imaging in radiation oncology. vol 8. 2021-01-19. PMID:33458413. |
this work compared impt relative to volumetric modulated arc therapy (vmat) during hippocampal avoidance whole brain radiation therapy (ha wbrt). |
2021-01-19 |
2023-08-13 |
Not clear |
| Anca-Ligia Grosu, Lars Frings, Iryna Bentsalo, Oliver Oehlke, Franziska Brenner, Angelika Bilger, Jamina Tara Fennell, Thomas Rothe, Sabine Schneider-Fuchs, Erika Graf, Claudia Schmoor, Jürgen Beck, Gerhild Becker, Michael Bock, Karl Egger, Horst Urbach, Claas Lahmann, Ilinca Pop. Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) - a phase II prospective randomized multicenter trial (NOA-14, ARO 2015-3, DKTK-ROG). BMC cancer. vol 20. issue 1. 2021-01-11. PMID:32513138. |
aim of this trial is to assess the efficacy and safety of a new treatment method, the wbrt with hippocampus avoidance (ha) combined with the simultaneous integrated boost (sib) on metastases/resection cavities (ha-wbrt+sib). |
2021-01-11 |
2023-08-13 |
Not clear |
| Kathleen G Bryant, Jacqueline M Barke. Arbitration of Approach-Avoidance Conflict by Ventral Hippocampus. Frontiers in neuroscience. vol 14. 2021-01-06. PMID:33390895. |
taken together with the extant, classical literature on hippocampal function, we propose that these new findings suggest that vhpc circuits balance behavioral response to conflicting stimuli in a manner that is both state- and context-dependent and, further, that disruption of specific vhpc circuits tips the balance in favor of biased approach or avoidance behavioral strategies. |
2021-01-06 |
2023-08-13 |
Not clear |
| Andressa Radiske, Maria Carolina Gonzalez, Sergio Conde-Ocazionez, Janine I Rossato, Cristiano A Köhler, Martín Cammarot. Cross-Frequency Phase-Amplitude Coupling between Hippocampal Theta and Gamma Oscillations during Recall Destabilizes Memory and Renders It Susceptible to Reconsolidation Disruption. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 33. 2021-01-04. PMID:32661022. |
avoidance memory reactivation at recall triggers theta-gamma hippocampal phase amplitude coupling (hpac) only when it elicits hippocampus-dependent reconsolidation. |
2021-01-04 |
2023-08-13 |
rat |
| Susan Sangha, Maria M Diehl, Hadley C Bergstrom, Michael R Dre. Know safety, no fear. Neuroscience and biobehavioral reviews. vol 108. 2020-12-28. PMID:31738952. |
in this review, we discuss mechanisms of suppressing fear responses during stimulus discrimination, fear extinction, and active avoidance, focusing on the well-studied tripartite circuit consisting of the amygdala, medial prefrontal cortex and hippocampus. |
2020-12-28 |
2023-08-13 |
Not clear |
| Luciano Román-Albasini, Gabriela Díaz-Véliz, Felipe Antonio Olave, Felipe Ignacio Aguayo, Gonzalo García-Rojo, Wladimir Antonio Corrales, Juan Pablo Silva, Ana María Ávalos, Paulina S Rojas, Esteban Aliaga, Jenny Lucy Fiedle. Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically stressed male rats. Neurobiology of stress. vol 13. 2020-12-22. PMID:33344690. |
24 hr after treatments, rats were either evaluated for behavioral tests (active avoidance, anxiety-like behavior and object location) or euthanized for western blot analyses of hippocampal whole extract and synaptoneurosome-enriched fractions. |
2020-12-22 |
2023-08-13 |
rat |
| Joseph P Weine. Neurocognitive Outcomes for Patients With Brain Metastasis in the Modern Era: Benefit of Treatment With Hippocampal Avoidance Whole-Brain Radiotherapy Plus Memantine. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. vol 38. issue 10. 2020-12-14. PMID:32058847. |
neurocognitive outcomes for patients with brain metastasis in the modern era: benefit of treatment with hippocampal avoidance whole-brain radiotherapy plus memantine. |
2020-12-14 |
2023-08-13 |
Not clear |
| Michael Mayinger, Nicolaus Andratschk. [Role of hippocampal avoidance during therapeutic whole-brain radiotherapy]. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. vol 196. issue 9. 2020-12-10. PMID:32519024. |
[role of hippocampal avoidance during therapeutic whole-brain radiotherapy]. |
2020-12-10 |
2023-08-13 |
Not clear |
| Joseph A Bovi, Stephanie L Pugh, David Sabsevitz, Clifford G Robinson, Eric Paulson, Minesh P Mehta, Vinai Gondi, Vijayananda Kundapur, Mark S Shahin, Samuel T Chao, Mitch Machtay, Albert S DeNittis, Nadia N Laack, Jeffrey N Greenspoon, Kathleen N Moore, Jiayi Huang, Michael M Dominello, Lisa A Kachni. Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933. Advances in radiation oncology. vol 4. issue 4. 2020-11-26. PMID:31673651. |
nrg oncology's rtog 0933 demonstrated benefits to memory preservation after hippocampal avoidant whole-brain radiation therapy (ha-wbrt), the avoidance of radiation dose to the hippocampus (using intensity modulated radiation planning and delivery techniques) during wbrt, supporting the hypothesis of hippocampal radiosensitivity and associated memory specificity. |
2020-11-26 |
2023-08-13 |
Not clear |
| Vanise Hallas Uberti, Betânia Souza de Freitas, Patrícia Molz, Elke Bromberg, Nadja Schröde. Iron Overload Impairs Autophagy: Effects of Rapamycin in Ameliorating Iron-Related Memory Deficits. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31664701. |
results showed that iron given in the neonatal period impaired inhibitory avoidance memory and induced a decrease in proteins critically involved in the autophagy pathway, beclin-1 and lc3, in the hippocampus. |
2020-11-25 |
2023-08-13 |
rat |
| James M Taylor, Chad G Rusthoven, Drew Moghanak. Prophylactic cranial irradiation or MRI surveillance for extensive stage small cell lung cancer. Journal of thoracic disease. vol 12. issue 10. 2020-11-20. PMID:33209461. |
recent improvements in systemic disease control with the use of immunotherapy and reductions in the toxicity attributable to pci with hippocampal avoidance and memantine have reignited the discussion. |
2020-11-20 |
2023-08-13 |
Not clear |
| Sahaja Acharya, Shengjie Wu, Jason M Ashford, Christopher L Tinkle, John T Lucas, Ibrahim Qaddoumi, Amar Gajjar, Matthew J Krasin, Heather M Conklin, Thomas E Merchan. Association between hippocampal dose and memory in survivors of childhood or adolescent low-grade glioma: a 10-year neurocognitive longitudinal study. Neuro-oncology. vol 21. issue 9. 2020-11-10. PMID:30977510. |
hippocampal avoidance has been suggested as a strategy to reduce short-term memory decline in adults receiving whole-brain radiation therapy (rt). |
2020-11-10 |
2023-08-13 |
Not clear |
| Roshan Sethi, Shannon MacDonal. Hippocampus avoidance in pediatric patients. Neuro-oncology. vol 21. issue 9. 2020-10-30. PMID:31237952. |
hippocampus avoidance in pediatric patients. |
2020-10-30 |
2023-08-13 |
Not clear |
| Jiayi Zhao, Wei Bi, Shu Xiao, Xin Lan, Xiaofeng Cheng, Jiawei Zhang, Daxiang Lu, Wei Wei, Yanping Wang, Hongmei Li, Yongmei Fu, Lihong Zh. Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice. Scientific reports. vol 9. issue 1. 2020-10-06. PMID:30962497. |
we found that lps treatment leads to sickness behavior and cognitive impairment in mice as shown in the morris water maze and passive avoidance test, and these effects were accompanied by microglia activation (labeled by ionized calcium binding adaptor molecule-1, iba-1) and neuronal cell loss (labeled by microtubule-associated protein 2, map-2) in the hippocampus. |
2020-10-06 |
2023-08-13 |
mouse |
| Jarid Goodman, Christa K McIntyr. Impaired Spatial Memory and Enhanced Habit Memory in a Rat Model of Post-traumatic Stress Disorder. Frontiers in pharmacology. vol 8. 2020-10-01. PMID:29018340. |
the influence of sps on hippocampal spatial memory and dls habit memory observed in the present study may be relevant to understanding some common features of ptsd, including hippocampal memory deficits, habit-like avoidance responses to trauma-related stimuli, and greater likelihood of developing drug addiction and alcoholism. |
2020-10-01 |
2023-08-13 |
rat |
| Marta Balietti, Giorgia Fattorini, Arianna Pugliese, Daniele Marcotulli, Luca Bragina, Fiorenzo Cont. Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins. Frontiers in aging neuroscience. vol 10. 2020-10-01. PMID:29670520. |
analysis of syt1 levels in the whole hippocampus of rats selected by the morris water maze (mwm) test only failed to highlight a difference, whereas analysis of syt1 levels in the whole hippocampus of rats categorized by both the mwm and the step-through passive avoidance (stpa) tests demonstrated a significant increase of syt1 level in impaired rats. |
2020-10-01 |
2023-08-13 |
rat |
| Rana Malekiyan, Alireza Abdanipour, Davood Sohrabi, Iraj Jafari Anarkool. Antioxidant and neuroprotective effects of lycopene and insulin in the hippocampus of streptozotocin-induced diabetic rats. Biomedical reports. vol 10. issue 1. 2020-10-01. PMID:30588303. |
in the present study the antioxidant and neuroprotective effects of insulin and lycopene on passive avoidance memory, total antioxidant capacity (tac), malondialdehyde activity (mda) and prevention of apoptosis in the hippocampus streptozotocin-induced diabetic rats were examined. |
2020-10-01 |
2023-08-13 |
rat |
| Teresa Joy, Muddanna S Rao, Sampath Madhyastha, Keshav Pa. Effect of N-Acetyl Cysteine on Intracerebroventricular Colchicine Induced Cognitive Deficits, Beta Amyloid Pathology, and Glial Cells. Neuroscience journal. vol 2019. 2020-10-01. PMID:31139638. |
cognitive function was evaluated in active avoidance test; beta amyloid protein, beta amyloid plaques, astrocytes, and microglia cells were quantified using immunohistochemistry in hippocampal and prefrontal cortices. |
2020-10-01 |
2023-08-13 |
human |