| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Sunpil Kim, Jeongyeon Kim, Yongmin Mason Park, Pann-Ghill Suh, C Justin Le. Visuosocial Preference Memory, but Not Avoidance Memory, Requires PLCγ1 in the CA2 Hippocampus. Experimental neurobiology. vol 31. issue 5. 2022-11-09. PMID:36351843. |
visuosocial preference memory, but not avoidance memory, requires plcγ1 in the ca2 hippocampus. |
2022-11-09 |
2023-08-14 |
mouse |
| Jaqueline M Franzen, Isabel Werle, Felipe Vanz, Bruno Biscaia de Oliveira, Laura Maria Martins Nascimento, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT Neuropharmacology. 2022-11-05. PMID:36334768. |
cannabidiol attenuates fear memory expression in female rats via hippocampal 5-ht growing evidence from male rodent and human studies suggests that cannabidiol (cbd) modulates the expression of aversive memories and anxiety-related responses. |
2022-11-05 |
2023-08-14 |
human |
| Emma McKeon, Jennifer Torres, Andrew M Kazama, Jocelyne Bachevalier, Jessica Rape. Differential responses toward conditioned and unconditioned stimuli, but decreased hypothalamic-pituitary-adrenal axis responsiveness in neonatal hippocampal lesioned monkeys. Developmental cognitive neuroscience. vol 58. 2022-10-21. PMID:36270099. |
responses toward social, innate, and learned aversive stimuli, fear potentiated acoustic startle, and pituitary-adrenal function were investigated in 13 adult rhesus monkeys with neonatal hippocampal lesions (neo-hibo=6) and controls (neo-c=7). |
2022-10-21 |
2023-08-14 |
monkey |
| Fengmei Wei, Xiao Deng, Bo Ma, Wenhao Li, Yajie Chen, Long Zhao, Yishu Zhang, Tingjuan Zheng, Donghua Xian, Yunqing He, Lang Zhang, Yuhong Jin. Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR. Cellular and molecular neurobiology. 2022-10-14. PMID:36239833. |
the dorsal hippocampus is involved in behavioral avoidance regulation. |
2022-10-14 |
2023-08-14 |
mouse |
| Fengmei Wei, Xiao Deng, Bo Ma, Wenhao Li, Yajie Chen, Long Zhao, Yishu Zhang, Tingjuan Zheng, Donghua Xian, Yunqing He, Lang Zhang, Yuhong Jin. Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR. Cellular and molecular neurobiology. 2022-10-14. PMID:36239833. |
it is unclear how experiences such as the neonatal stress of maternal deprivation (md) and post-weaning environmental enrichment (ee) affect avoidance behavior and the dorsal hippocampal parameters, including neuronal morphology, corticotrophin-releasing hormone (crh) signaling, and oxytocin receptor (otr) level. |
2022-10-14 |
2023-08-14 |
mouse |
| Fengmei Wei, Xiao Deng, Bo Ma, Wenhao Li, Yajie Chen, Long Zhao, Yishu Zhang, Tingjuan Zheng, Donghua Xian, Yunqing He, Lang Zhang, Yuhong Jin. Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR. Cellular and molecular neurobiology. 2022-10-14. PMID:36239833. |
the study illustrates how md and ee affect avoidance behaviors, hippocampal neuron morphology, and crh and otr levels. |
2022-10-14 |
2023-08-14 |
mouse |
| Ashley J McFalls, Christopher Jenney, Rachel S Stanford, Emma Woodward, Andras Hajnal, Patricia S Grigson, Kent E Vran. Greater Avoidance of a Saccharin Cue Paired with Passive Delivery of Heroin is Associated with a Select Increase in Expression of CRFR2 and CRFbp in the Hippocampus in Rats. Brain research bulletin. 2022-10-13. PMID:36228871. |
greater avoidance of a saccharin cue paired with passive delivery of heroin is associated with a select increase in expression of crfr2 and crfbp in the hippocampus in rats. |
2022-10-13 |
2023-08-14 |
rat |
| Rodríguez de Dios N, Martínez Moñino A, Cristina Liu, Rafael Jiménez, Núria Antón, Miguel Prieto, Francesco Amorelli, Palmira Foro, Manuel Algara, Xavier Sanz, Ismael Membrive, Ana Reig, Jaume Quera, Enric Fernández-Velilla, Oscar Per. Machine learning-based automated planning for hippocampal avoidance prophylactic cranial irradiation. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2022-10-04. PMID:36194382. |
machine learning-based automated planning for hippocampal avoidance prophylactic cranial irradiation. |
2022-10-04 |
2023-08-14 |
Not clear |
| Rodríguez de Dios N, Martínez Moñino A, Cristina Liu, Rafael Jiménez, Núria Antón, Miguel Prieto, Francesco Amorelli, Palmira Foro, Manuel Algara, Xavier Sanz, Ismael Membrive, Ana Reig, Jaume Quera, Enric Fernández-Velilla, Oscar Per. Machine learning-based automated planning for hippocampal avoidance prophylactic cranial irradiation. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2022-10-04. PMID:36194382. |
design and evaluate a knowledge-based model using commercially available artificial intelligence tools for automated treatment planning to efficiently generate clinically acceptable hippocampal avoidance prophylactic cranial irradiation (ha-pci) plans in patients with small-cell lung cancer. |
2022-10-04 |
2023-08-14 |
Not clear |
| Jessica Rosa, Jociane de Carvalho Myskiw, Natalia Gindri Fiorenza, Cristiane Regina Guerino Furini, Gerson Guilherme Sapiras, Ivan Izquierd. Hippocampal cholinergic receptors and the mTOR participation in fear-motivated inhibitory avoidance extinction memory. Behavioural brain research. 2022-09-30. PMID:36179804. |
hippocampal cholinergic receptors and the mtor participation in fear-motivated inhibitory avoidance extinction memory. |
2022-09-30 |
2023-08-14 |
rat |
| Jessica Rosa, Jociane de Carvalho Myskiw, Natalia Gindri Fiorenza, Cristiane Regina Guerino Furini, Gerson Guilherme Sapiras, Ivan Izquierd. Hippocampal cholinergic receptors and the mTOR participation in fear-motivated inhibitory avoidance extinction memory. Behavioural brain research. 2022-09-30. PMID:36179804. |
evidence has demonstrated the hippocampal cholinergic system and the mammalian target of rapamycin (mtor) participation during the memory formation of aversive events. |
2022-09-30 |
2023-08-14 |
rat |
| Jessica Rosa, Jociane de Carvalho Myskiw, Natalia Gindri Fiorenza, Cristiane Regina Guerino Furini, Gerson Guilherme Sapiras, Ivan Izquierd. Hippocampal cholinergic receptors and the mTOR participation in fear-motivated inhibitory avoidance extinction memory. Behavioural brain research. 2022-09-30. PMID:36179804. |
this study assessed the role of these systems in the hippocampus for the extinction memory process by submitting male wistar rats to fear-motivated step-down inhibitory avoidance (ia). |
2022-09-30 |
2023-08-14 |
rat |
| Yan Chen, Chen-Yao Wang, Gui-Ying Zan, Song-Yu Yao, Ying-Zhi Deng, Xue-Lian Shu, Wei-Wei Wu, Yan Ma, Yu-Jun Wang, Chang-Xi Yu, Jing-Gen Li. Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion. Acta pharmacologica Sinica. 2022-09-20. PMID:36127507. |
upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion. |
2022-09-20 |
2023-08-14 |
mouse |
| Yan Chen, Chen-Yao Wang, Gui-Ying Zan, Song-Yu Yao, Ying-Zhi Deng, Xue-Lian Shu, Wei-Wei Wu, Yan Ma, Yu-Jun Wang, Chang-Xi Yu, Jing-Gen Li. Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion. Acta pharmacologica Sinica. 2022-09-20. PMID:36127507. |
this study demonstrates that upregulation of dynorphin/kor system in the dorsal hippocampus plays a critical role in the formation of aversive emotion associated with morphine withdrawal, suggesting that kor antagonists may have therapeutic value for the treatment of opioid withdrawal-induced mood-related disorders. |
2022-09-20 |
2023-08-14 |
mouse |
| Martin G Codagnone, Nirit Kara, Anna Ratsika, Brunno Rocha Levone, Marcel van de Wouw, Laura A Tan, Jacobi I Cunningham, Connie Sanchez, John F Cryan, Olivia F O'Lear. Inhibition of FKBP51 induces stress resilience and alters hippocampal neurogenesis. Molecular psychiatry. 2022-09-14. PMID:36104438. |
in vivo, chronic safit2 administration prevented stress-induced social avoidance, decreased anxiety in the novelty-induced hypophagia test, and prevented stress-induced anxiety in the open field but did not alter adult hippocampal neurogenesis in stressed animals. |
2022-09-14 |
2023-08-14 |
mouse |
| Polymnia Georgiou, Panos Zanos, Ta-Chung M Mou, Xiaoxian An, Danielle M Gerhard, Dilyan I Dryanovski, Liam E Potter, Jaclyn N Highland, Carleigh E Jenne, Brent W Stewart, Katherine J Pultorak, Peixiong Yuan, Chris F Powels, Jacqueline Lovett, Edna F R Pereira, Sarah M Clark, Leonardo H Tonelli, Ruin Moaddel, Carlos A Zarate, Ronald S Duman, Scott M Thompson, Todd D Goul. Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nature neuroscience. 2022-08-30. PMID:36042309. |
this human-male-scent-induced aversion and stress susceptibility was mediated by the activation of corticotropin-releasing factor (crf) neurons in the entorhinal cortex that project to hippocampal area ca1. |
2022-08-30 |
2023-08-14 |
mouse |
| Keerti Gupta, Jitendra Vishwakarma, Asmita Garg, Rukmani Pandey, Veena Jain, Raksha Gupta, Uttara Das, Somendu Roy, Sanghamitra Bandyopadhya. Arsenic Induces GSK3β-dependent p-tau, neuronal apoptosis and cognitive impairment via an interdependent hippocampal ERα and IL-1/IL-1R1 mechanism in female rats. Toxicological sciences : an official journal of the Society of Toxicology. 2022-08-22. PMID:35993674. |
we observed that ppt, il-1ra and the gsk3β inhibitor, licl, reduced hippocampal neuronal cleaved caspase-3 and tunel+ve apoptotic count, and decreased the number of errors during learning and increased the saving-memory for y-maze test and retention performance for passive avoidance test in arsenic-treated rats. |
2022-08-22 |
2023-08-14 |
rat |
| S Mokarrami, M Jahanshahi, L Elyasi, H Badelisarkala, M Khalil. Naringin prevents the reduction of the number of neurons and the volume of CA1 in a Scopolamine-Induced animal model of Alzheimer's disease (AD): A stereological study. The International journal of neuroscience. 2022-07-21. PMID:35861379. |
naringin administration at doses of 50, 100, and 200 mg/kg for 14 consecutive days, increased neuron density and the total number of neurons in the hippocampal ca1 area.we concluded that naringin could be effective in improving scopolamine-induced inhibitory passive avoidance memory deficits and that it appeared to increase the volume and density as well as the total number of neurons in the ca1 area of the alzheimer's rat hippocampus. |
2022-07-21 |
2023-08-14 |
rat |
| Sang-Seo Park, Seong-Hyun Kim, Chang-Ju Kim, Mal-Soon Shin, Yun-Jin Park, Tae-Woon Ki. Effects of exercise and microbiota transplant on the memory of obesity-induced mice. Journal of exercise rehabilitation. vol 18. issue 3. 2022-07-18. PMID:35846232. |
the short-term memory and spatial learning memory were determined by step-down avoidance test and morris water maze task, immunohistochemistry for glial fibrillary acidic protein, western blot analysis for brain-derived neurotrophic factor and tropomyosin receptor kinase b were performed in the hippocampus. |
2022-07-18 |
2023-08-14 |
mouse |