| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaohua Ma, Hao Zhong, Xuemei Liu, Liping Wan. Spatial Distribution of Neurons Expressing Single, Double, and Triple Molecular Characteristics of Glutamatergic, Dopaminergic, or GABAergic Neurons in the Mouse Ventral Tegmental Area. Journal of molecular neuroscience : MN. 2023-05-27. PMID:37243808. |
the ventral tegmental area (vta) is a heterogeneous midbrain area that plays a significant role in diverse neural processes such as reward, aversion, and motivation. |
2023-05-27 |
2023-08-14 |
mouse |
| Emily D Pr Vost, Alysabeth Phillips, Kristoffer Lauridsen, Gunnar Enserro, Bodhi Rubinstein, Daniel Alas, Dillon J McGovern, Annie Ly, Makaila Banks, Connor McNulty, Yoon Seok Kim, Lief E Fenno, Charu Ramakrishnan, Karl Deisseroth, David H Roo. Monosynaptic inputs to ventral tegmental area glutamate and GABA co-transmitting neurons. bioRxiv : the preprint server for biology. 2023-04-17. PMID:37066408. |
a unique population of ventral tegmental area (vta) neurons co-transmits glutamate and gaba as well as functionally signals rewarding and aversive outcomes. |
2023-04-17 |
2023-08-14 |
mouse |
| Emily D Pr Vost, Alysabeth Phillips, Kristoffer Lauridsen, Gunnar Enserro, Bodhi Rubinstein, Daniel Alas, Dillon J McGovern, Annie Ly, Makaila Banks, Connor McNulty, Yoon Seok Kim, Lief E Fenno, Charu Ramakrishnan, Karl Deisseroth, David H Roo. Monosynaptic inputs to ventral tegmental area glutamate and GABA co-transmitting neurons. bioRxiv : the preprint server for biology. 2023-04-17. PMID:37066408. |
for both pathways, behaviors induced by stimulation were uncorrelated with vta vglut2+vgat+ neuron activity, suggesting that vglut2+vgat+ neurons are integrators of signals related to aversive outcomes but not of aversion-induced behavioral kinematics. |
2023-04-17 |
2023-08-14 |
mouse |
| Alina Lakosa, Anaïs Rahimian, Flavio Tomasi, Fabio Marti, Lauren M Reynolds, Léa Tochon, Vincent David, Anne Danckaert, Candice Canonne, Sylvana Tahraoui, Fabrice de Chaumont, Benoît Forget, Uwe Maskos, Morgane Besso. Impact of the gut microbiome on nicotine's motivational effects and glial cells in the ventral tegmental area in male mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-03-18. PMID:36932179. |
we further show that gut microbiota depletion enhances the response to nicotine of dopaminergic neurons of the posterior ventral tegmental area (pvta), and alters nicotine's rewarding and aversive effects in an intra-vta self-administration procedure. |
2023-03-18 |
2023-08-14 |
mouse |
| Yuqi Zhang, Longyu Ma, Xueying Zhang, Lupeng Yue, Jiaxin Wang, Jie Zheng, Shuang Cui, Feng-Yu Liu, Zhiyan Wang, You Wan, Ming Y. Deep brain stimulation in the lateral habenula reverses local neuronal hyperactivity and ameliorates depression-like behaviors in rats. Neurobiology of disease. 2023-03-09. PMID:36893902. |
nevertheless, dbs downregulated local field potential power, reversed the cums-induced increase of lhb burst firing and neuronal hyperactivity to aversive stimuli, and decreased the coherence between lhb and ventral tegmental area (vta). |
2023-03-09 |
2023-08-14 |
rat |
| Quentin Montardy, Zheng Zhou, Zhuogui Lei, Xuemei Liu, Pengyu Zeng, Chen Chen, Yuanming Liu, Paula Sanz-Leon, Kang Huang, Liping Wan. Characterization of glutamatergic VTA neural population responses to aversive and rewarding conditioning in freely-moving mice. Science bulletin. vol 64. issue 16. 2023-01-20. PMID:36659688. |
characterization of glutamatergic vta neural population responses to aversive and rewarding conditioning in freely-moving mice. |
2023-01-20 |
2023-08-14 |
mouse |
| Quentin Montardy, Zheng Zhou, Zhuogui Lei, Xuemei Liu, Pengyu Zeng, Chen Chen, Yuanming Liu, Paula Sanz-Leon, Kang Huang, Liping Wan. Characterization of glutamatergic VTA neural population responses to aversive and rewarding conditioning in freely-moving mice. Science bulletin. vol 64. issue 16. 2023-01-20. PMID:36659688. |
the ventral tegmental area (vta) is a midbrain structure known to integrate aversive and rewarding stimuli, but little is known about the role of vta glutamatergic (vglut2) neurons in these functions. |
2023-01-20 |
2023-08-14 |
mouse |
| Susanna Molas, Rubing Zhao-Shea, Timothy G Freels, Andrew R Tappe. Viral tracing confirms paranigral ventral tegmental area dopaminergic inputs to the interpeduncular nucleus where dopamine release encodes motivated exploration. eNeuro. 2023-01-04. PMID:36599671. |
however, recent data indicate vta daergic neurons are functionally heterogeneous with emerging roles in aversive signaling, salience, and novelty, based in part on anatomical location and projection, highlighting a need to functionally characterize the repertoire of vta daergic efferents in motivated behavior. |
2023-01-04 |
2023-08-14 |
mouse |
| Susanna Molas, Rubing Zhao-Shea, Timothy G Freels, Andrew R Tappe. Viral tracing confirms paranigral ventral tegmental area dopaminergic inputs to the interpeduncular nucleus where dopamine release encodes motivated exploration. eNeuro. 2023-01-04. PMID:36599671. |
previous work identifying a mesointerpeduncular circuit consisting of vta daergic neurons projecting to the interpeduncular nucleus (ipn), a midbrain area implicated in aversion, anxiety-like behavior, and familiarity, has recently come into question. |
2023-01-04 |
2023-08-14 |
mouse |
| Xiaoyan Ding, Mengdie Yang, Ning Wu, Jin Li, Rui Son. Blockade of dopamine D3 receptor in ventral tegmental area attenuating contextual fear memory. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592493. |
then, we identified that microinjection of yqa14 (1 μg/0.2 μl/side) in vta before the aversive stimuli in the training session or during days subsequent to the shock significantly meliorated the freezing behaviors in the inescapable electric foot-shock model. |
2023-01-02 |
2023-08-14 |
Not clear |
| Dillon J McGovern, Annie Ly, Koy L Ecton, David T Huynh, Emily D Prévost, Shamira C Gonzalez, Connor J McNulty, Andrew R Rau, Shane T Hentges, Tanya L Daigle, Bosiljka Tasic, Michael V Baratta, David H Roo. Ventral tegmental area glutamate neurons mediate nonassociative consequences of stress. Molecular psychiatry. 2022-11-27. PMID:36437312. |
recent data demonstrate that ventral tegmental area (vta) neurons expressing the vesicular glutamate transporter 2 (vglut2) signal and causally contribute to behaviors that involve aversive or threatening stimuli. |
2022-11-27 |
2023-08-14 |
mouse |
| Dillon J McGovern, Annie Ly, Koy L Ecton, David T Huynh, Emily D Prévost, Shamira C Gonzalez, Connor J McNulty, Andrew R Rau, Shane T Hentges, Tanya L Daigle, Bosiljka Tasic, Michael V Baratta, David H Roo. Ventral tegmental area glutamate neurons mediate nonassociative consequences of stress. Molecular psychiatry. 2022-11-27. PMID:36437312. |
our results provide causal evidence that mice can be used for identifying stressor controllability circuitry and that vta vglut2 neurons contribute to transsituational stressor outcomes, such as social avoidance, exaggerated fear, or anxiety-like behavior that are observed within trauma-related disorders. |
2022-11-27 |
2023-08-14 |
mouse |
| Wanqi Che. Neural circuits provide insights into reward and aversion. Frontiers in neural circuits. vol 16. 2022-11-17. PMID:36389177. |
the aim of this paper is to summarize the latest findings on the mechanisms of the neural circuits associated with reward and aversion in a review of previous studies with a focus on the ventral tegmental area (vta), nucleus accumbens (nac), and basal forebrain (bf). |
2022-11-17 |
2023-08-14 |
Not clear |
| Xinjian Zhang, Daisuke Tsuboi, Yasuhiro Funahashi, Yukie Yamahashi, Kozo Kaibuchi, Taku Naga. Phosphorylation Signals Downstream of Dopamine Receptors in Emotional Behaviors: Association with Preference and Avoidance. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232945. |
dopamine regulates emotional behaviors, including rewarding and aversive behaviors, through the mesolimbic dopaminergic pathway, which projects dopamine neurons from the ventral tegmental area to the nucleus accumbens (nac). |
2022-10-14 |
2023-08-14 |
Not clear |
| Antony D Abraham, Sanne M Casello, Benjamin B Land, Charles Chavki. Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. Addiction neuroscience. vol 1. 2022-09-30. PMID:36176476. |
transient optogenetic inhibition of vta dopamine neurons with aav5-dio-swichr was acutely aversive in a real time place preference assay and blunted cocaine cpp when inhibition was administered concurrently with cocaine conditioning. |
2022-09-30 |
2023-08-14 |
mouse |
| Loïc Broussot, Thomas Contesse, Renan Costa-Campos, Christelle Glangetas, Léa Royon, Hugo Fofo, Thomas Lorivel, François Georges, Sebastian P Fernandez, Jacques Bari. A non-canonical GABAergic pathway to the VTA promotes unconditioned freezing. Molecular psychiatry. 2022-09-20. PMID:36127430. |
notably, this aversive information is subsequently conveyed from the vta to the amygdala via a discrete gabaergic pathway. |
2022-09-20 |
2023-08-14 |
Not clear |
| Christine Liu, Amanda J Tose, Jeroen P H Verharen, Yichen Zhu, Lilly W Tang, Johannes W de Jong, Jessica X Du, Kevin T Beier, Stephan Lamme. An inhibitory brainstem input to dopamine neurons encodes nicotine aversion. Neuron. 2022-08-03. PMID:35921846. |
finally, inhibition of ldt gaba terminals in vta prevents nicotine aversion. |
2022-08-03 |
2023-08-14 |
mouse |
| Marta E Soden, Joshua X Yee, Beatriz Cuevas, Ariana Rastani, Jordan Elum, Larry S Zweife. Distinct Encoding of Reward and Aversion by Peptidergic BNST Inputs to the VTA. Frontiers in neural circuits. vol 16. 2022-07-21. PMID:35860212. |
distinct encoding of reward and aversion by peptidergic bnst inputs to the vta. |
2022-07-21 |
2023-08-14 |
Not clear |
| Fernando Castillo Díaz, Juliana F Dalto, Magdalena Pereyra, Jorge H Medin. Dopamine neurotransmission in the VTA regulates aversive memory formation and persistence. Physiology & behavior. 2022-05-24. PMID:35609721. |
dopamine (da) neurons in the ventral tegmental area (vta) innervating several limbic and neocortical regions of the mammalian brain have long been implicated in motivation, rewarding and aversive behaviors, and memory processing. |
2022-05-24 |
2023-08-13 |
Not clear |
| Fernando Castillo Díaz, Juliana F Dalto, Magdalena Pereyra, Jorge H Medin. Dopamine neurotransmission in the VTA regulates aversive memory formation and persistence. Physiology & behavior. 2022-05-24. PMID:35609721. |
however, less is known about the impact of da neurotransmission in the vta on aversive ltm. |
2022-05-24 |
2023-08-13 |
Not clear |