| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gian D Greenberg, Michael Q Steinman, Ian E Doig, Rebecca Hao, Brian C Traino. Effects of social defeat on dopamine neurons in the ventral tegmental area in male and female California mice. The European journal of neuroscience. vol 42. issue 12. 2016-10-17. PMID:26469289. |
this observation suggests that repeated exposure to aversive contexts is necessary to trigger activation of vta dopamine neurons. |
2016-10-17 |
2023-08-13 |
mouse |
| Gian D Greenberg, Michael Q Steinman, Ian E Doig, Rebecca Hao, Brian C Traino. Effects of social defeat on dopamine neurons in the ventral tegmental area in male and female California mice. The European journal of neuroscience. vol 42. issue 12. 2016-10-17. PMID:26469289. |
our results show that dopamine neurons in the vta are more responsive to social contexts in females and that the ventral vta in particular is sensitive to aversive contexts. |
2016-10-17 |
2023-08-13 |
mouse |
| Elizabeth N Holly, Klaus A Micze. Ventral tegmental area dopamine revisited: effects of acute and repeated stress. Psychopharmacology. vol 233. issue 2. 2016-08-08. PMID:26676983. |
aversive events rapidly and potently excite certain dopamine neurons in the ventral tegmental area (vta), promoting phasic increases in the medial prefrontal cortex and nucleus accumbens. |
2016-08-08 |
2023-08-13 |
Not clear |
| Elizabeth N Holly, Klaus A Micze. Ventral tegmental area dopamine revisited: effects of acute and repeated stress. Psychopharmacology. vol 233. issue 2. 2016-08-08. PMID:26676983. |
this is in apparent contradiction to a wealth of literature demonstrating that most vta dopamine neurons are strongly activated by reward and reward-predictive cues while inhibited by aversive stimuli. |
2016-08-08 |
2023-08-13 |
Not clear |
| Hui-Ling Wang, Jia Qi, Shiliang Zhang, Huikun Wang, Marisela Morale. Rewarding Effects of Optical Stimulation of Ventral Tegmental Area Glutamatergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631475. |
ventral tegmental area (vta) neurons play roles in reward and aversion. |
2016-03-28 |
2023-08-13 |
mouse |
| Heather N Lavezzi, Kenneth P Parsley, Daniel S Zah. Modulation of locomotor activation by the rostromedial tegmental nucleus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 3. 2016-03-15. PMID:25164249. |
the rostromedial tegmental nucleus (rmtg) is a strong inhibitor of dopamine neurons in the ventral tegmental area (vta) reported to influence neurobiological and behavioral responses to reward omission, aversive and fear-eliciting stimuli, and certain drugs of abuse. |
2016-03-15 |
2023-08-13 |
rat |
| Wolfgang M Pauli, Tobias Larsen, Sven Collette, Julian M Tyszka, Ben Seymour, John P O'Dohert. Distinct Contributions of Ventromedial and Dorsolateral Subregions of the Human Substantia Nigra to Appetitive and Aversive Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 42. 2016-01-25. PMID:26490862. |
here we scanned human participants with high-resolution fmri focused on the sn and vta while they participated in a sequential pavlovian conditioning paradigm involving an appetitive outcome (a pleasant juice), as well as an aversive outcome (an unpleasant bitter and salty flavor). |
2016-01-25 |
2023-08-13 |
human |
| Jonathan M Ehrich, Daniel I Messinger, Cerise R Knakal, Jamie R Kuhar, Selena S Schattauer, Michael R Bruchas, Larry S Zweifel, Brigitte L Kieffer, Paul E M Phillips, Charles Chavki. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 37. 2016-01-04. PMID:26377476. |
kappa opioid receptor-induced aversion requires p38 mapk activation in vta dopamine neurons. |
2016-01-04 |
2023-08-13 |
mouse |
| Jonathan M Ehrich, Daniel I Messinger, Cerise R Knakal, Jamie R Kuhar, Selena S Schattauer, Michael R Bruchas, Larry S Zweifel, Brigitte L Kieffer, Paul E M Phillips, Charles Chavki. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 37. 2016-01-04. PMID:26377476. |
in this study, we report that kor activation of p38α mapk in ventral tegmental (vta) dopaminergic neurons was required for conditioned place aversion (cpa) in mice. |
2016-01-04 |
2023-08-13 |
mouse |
| M Minami, S Id. How does pain induce negative emotion? Role of the bed nucleus of the stria terminalis in pain-induced place aversion. Current molecular medicine. vol 15. issue 2. 2015-12-18. PMID:25732152. |
recent optogenetic studies suggest that the suppression of vta daergic neurons is sufficient to induce place aversion. |
2015-12-18 |
2023-08-13 |
Not clear |
| M Minami, S Id. How does pain induce negative emotion? Role of the bed nucleus of the stria terminalis in pain-induced place aversion. Current molecular medicine. vol 15. issue 2. 2015-12-18. PMID:25732152. |
pain-induced place aversion may be due to the suppression of vta daergic neurons via the processing of nociceptive information within the bnst. |
2015-12-18 |
2023-08-13 |
Not clear |
| Nao Matsushita, Yoshikage Muroi, Ken-ichi Kinoshita, Toshiaki Ishi. Comparison of c-Fos expression in brain regions involved in maternal behavior of virgin and lactating female mice. Neuroscience letters. vol 590. 2015-09-14. PMID:25660234. |
the bed nucleus of striaterminalis (bnst), which innervates vta neurons to regulate both aversive and rewarding responses, showed increased number of c-fos-positive cells following pup presentation in virgin females, butnotin lactating females. |
2015-09-14 |
2023-08-13 |
mouse |
| Paweł Matulewicz, Jolanta Orzeł-Gryglewska, Łukasz Braszka, Piotr Zawistowski, Edyta Jurkowlanie. Hippocampal theta rhythm after local administration of procaine or amphetamine into the ventral tegmental area in fear conditioned rats. Neuroscience letters. vol 589. 2015-08-27. PMID:25617477. |
our results indicate that temporal inactivation of neuronal activity in the vta affects hippocampal theta rhythm linked with attentional immobility and suppresses avoidance response in fear conditioned animals. |
2015-08-27 |
2023-08-13 |
rat |
| A N Serkov, V I Maioro. [Δ-, θ-Modulation of the Ventral Tegmental Area Fast-Gamma Activity in the Course of Performance of Conditioned Avoidance Reflex in Rat]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 65. issue 3. 2015-08-27. PMID:26281234. |
[Δ-, θ-modulation of the ventral tegmental area fast-gamma activity in the course of performance of conditioned avoidance reflex in rat]. |
2015-08-27 |
2023-08-13 |
rat |
| A N Serkov, V I Maioro. [Δ-, θ-Modulation of the Ventral Tegmental Area Fast-Gamma Activity in the Course of Performance of Conditioned Avoidance Reflex in Rat]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 65. issue 3. 2015-08-27. PMID:26281234. |
the prestimulus expectation period of conditioned avoidance reflex features synchronized Δ-rhythm (1-4 hz) in the medial prefrontal cortex and the ventral tegmental area (vta), and synchronized θ-rhythm (6-8 hz) in the above-mentioned structures and the hippocampus. |
2015-08-27 |
2023-08-13 |
rat |
| Caitlin E Johnston, Daniel J Herschel, Amy W Lasek, Ronald P Hammer, Ella M Nikulin. Knockdown of ventral tegmental area mu-opioid receptors in rats prevents effects of social defeat stress: implications for amphetamine cross-sensitization, social avoidance, weight regulation and expression of brain-derived neurotrophic factor. Neuropharmacology. vol 89. 2015-07-15. PMID:25446676. |
knockdown of ventral tegmental area mu-opioid receptors in rats prevents effects of social defeat stress: implications for amphetamine cross-sensitization, social avoidance, weight regulation and expression of brain-derived neurotrophic factor. |
2015-07-15 |
2023-08-13 |
rat |
| Caitlin E Johnston, Daniel J Herschel, Amy W Lasek, Ronald P Hammer, Ella M Nikulin. Knockdown of ventral tegmental area mu-opioid receptors in rats prevents effects of social defeat stress: implications for amphetamine cross-sensitization, social avoidance, weight regulation and expression of brain-derived neurotrophic factor. Neuropharmacology. vol 89. 2015-07-15. PMID:25446676. |
social defeat stress causes social avoidance and long-lasting cross-sensitization to psychostimulants, both of which are associated with increased brain-derived neurotrophic factor (bdnf) expression in the ventral tegmental area (vta). |
2015-07-15 |
2023-08-13 |
rat |
| Caitlin E Johnston, Daniel J Herschel, Amy W Lasek, Ronald P Hammer, Ella M Nikulin. Knockdown of ventral tegmental area mu-opioid receptors in rats prevents effects of social defeat stress: implications for amphetamine cross-sensitization, social avoidance, weight regulation and expression of brain-derived neurotrophic factor. Neuropharmacology. vol 89. 2015-07-15. PMID:25446676. |
social stress exposure induced social avoidance and attenuated weight gain in animals with non-manipulated vta mors, but both these effects were prevented by vta mor knockdown. |
2015-07-15 |
2023-08-13 |
rat |
| Ninglei Sun, Steven R Laviolett. Dopamine receptor blockade modulates the rewarding and aversive properties of nicotine via dissociable neuronal activity patterns in the nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24896614. |
the mesolimbic pathway comprising the ventral tegmental area (vta) and projection terminals in the nucleus accumbens (nac) has been identified as a critical neural system involved in processing both the rewarding and aversive behavioral effects of nicotine. |
2015-07-10 |
2023-08-13 |
Not clear |
| David H Root, Alexander F Hoffman, Cameron H Good, Shiliang Zhang, Eduardo Gigante, Carl R Lupica, Marisela Morale. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 8. 2015-06-29. PMID:25716845. |
the lateral habenula (lhb) is involved in reward and aversion and is reciprocally connected with dopamine (da)-containing brain regions, including the ventral tegmental area (vta). |
2015-06-29 |
2023-08-13 |
rat |